Kai'Sa - League of Legends Champion
Win Rate
47.7%
Pick Rate
4.7%

Kai'Savs Cassiopeia

FMarksmanMage
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Kai'Sa vs Cassiopeia is a decisive matchup in LoL patch 26.14. Kai'Sa wins with a 66.7% win rate (+33.3%) over Cassiopeia based on 6 games. Kai'Sa holds the advantage in both the early and late game. Below you'll find the best Kai'Sa build, runes, laning stats, and strategies for the Kai'Sa vs Cassiopeia matchup.

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Kai'Sa Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Kai'Sa performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Kai'Sa - 66.7% win rate in this matchup
Kai'Sa
66.7% WR
VS
Cassiopeia vs Kai'Sa matchup - 33.3% win rate
Cassiopeia
33.3% WR

Who Wins the Kai'Sa vs Cassiopeia Matchup?

Kai'Sa wins the Kai'Sa vs Cassiopeia matchup
Winner
Kai'Sa
Matches: 6
66.7%
Win Rate
33.3%
6.3
CS / min
6.3
594
DMG / min
598
10,135
Gold / game
8,920
157
Heal / min
137
391
DMG Mitigated / min
367
0.1
CC / min
1.1
75.0%
Early Game WR
25.0%
50.0%
Late Game WR
50.0%

Kai'Sa vs Cassiopeia Matchup Summary

The Kai'Sa vs Cassiopeia matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Kai'Sa wins with a 66.7% win rate compared to Cassiopeia's 33.3%, giving Kai'Sa a 33.3 percentage point advantage. Kai'Sa dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Cassiopeia players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Cassiopeia leads by 1.0s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Kai'Sa players can confidently pick into Cassiopeia and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Cassiopeia away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Kai'Sa vs Cassiopeia Laning Phase Breakdown

Kai'Sa wins the laning phase against Cassiopeia in League of Legends

Kai'Sa is favored during the laning phase against Cassiopeia, winning 3 out of 5 key stat categories. Kai'Sa holds advantages in farming, gold income and sustain, making them the stronger laner in this matchup.

Farming
6.3Kai'Sa
6.3Cassiopeia
Kai'Sa and Cassiopeia farm at nearly identical rates in this matchup, with only a 0.0 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
594Kai'Sa
598Cassiopeia
Damage output is virtually even between Kai'Sa and Cassiopeia, with only 4 DMG/min separating them. Fights in this matchup are decided more by ability timing and positioning than raw damage numbers, making mechanical skill the deciding factor in trades.
Economy
10,135Kai'Sa
8,920Cassiopeia
Kai'Sa generates a commanding 1,215 more gold per game than Cassiopeia. This substantial economic advantage means Kai'Sa consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Cassiopeia should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.1Kai'Sa
1.1Cassiopeia
Cassiopeia brings significantly more crowd control than Kai'Sa, with 1.0 more seconds of CC per minute. This large utility gap makes Cassiopeia far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Kai'Sa should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
547Kai'Sa
504Cassiopeia
Kai'Sa and Cassiopeia have comparable sustain profiles, with only 43 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Early Game vs Late Game

Early Game
Kai'Sa
75.0%
+50.0% advantage
Kai'Sa early game win rateKai'Sa75.0%
Cassiopeia early game win rateCassiopeia25.0%
Late Game
Kai'Sa
50.0%
+0.0% advantage
Kai'Sa late game win rateKai'Sa50.0%
Cassiopeia late game win rateCassiopeia50.0%

Kai'Sa dominates the early game (first 15 minutes) with a commanding 75.0% win rate — a 50.0 percentage point lead over Cassiopeia. This lopsided early game means Kai'Sa can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Kai'Sa at 50.0% win rate — only 0.0 points ahead of Cassiopeia. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

Kai'Sa holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Cassiopeia players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Kai'Sa Runes Against Cassiopeia

Precision rune tree - Kai'Sa primary runes vs CassiopeiaPrecision
Lethal Tempo - best Kai'Sa rune vs CassiopeiaPresence of Mind - best Kai'Sa rune vs CassiopeiaLegend: Bloodline - best Kai'Sa rune vs CassiopeiaCoup de Grace - best Kai'Sa rune vs Cassiopeia
Inspiration rune tree - Kai'Sa secondary runes vs CassiopeiaInspiration
Magical Footwear - best Kai'Sa rune vs CassiopeiaBiscuit Delivery - best Kai'Sa rune vs Cassiopeia
100.0% WR

Running Precision primary with Inspiration secondary allows Kai'Sa to press their advantage against Cassiopeia, amplifying the strengths that make this a favorable matchup.


Kai'Sa matchup data for League of Legends patch 26.14. The table below shows Kai'Sa's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Kai'Sa build, runes, laning stats, and early vs late game analysis for that specific matchup.

Kai'Sa matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.16%4756.585713,43449.5%45.5%
41.26%4126.882212,78645.6%37.7%
49.87%3856.690113,90248.2%50.8%
45.58%2946.887112,82243.5%47.6%
50.20%2556.684313,05457.7%44.4%
56.85%2416.995214,01260.4%54.7%
46.92%2116.889913,09557.0%39.0%
49.46%1847.088013,02152.8%46.2%
48.24%1706.885713,03653.7%44.7%
46.97%1326.688513,82941.7%50.0%
49.62%1316.583714,12855.6%45.5%
52.68%1127.11,00314,86653.5%52.2%
51.35%1116.795314,01969.6%38.5%
48.04%1026.985312,30550.0%46.1%
39.02%826.992513,15027.8%47.8%
53.09%816.893713,70567.7%42.5%
50.65%777.281613,54851.5%50.0%
47.83%697.187813,74550.0%46.0%
62.12%666.888713,85770.4%56.4%
38.46%656.275411,51131.0%44.4%
44.62%656.786413,52639.4%50.0%
43.86%576.491313,32127.3%54.3%
45.61%576.585614,00739.1%50.0%
43.40%537.487513,29942.9%43.8%
50.00%446.576710,37757.7%38.9%
31.71%416.877013,05435.7%29.6%
51.28%397.087412,81042.1%60.0%
44.44%366.593513,40230.8%52.2%
62.86%357.087113,64650.0%71.4%
50.00%326.696913,12550.0%50.0%
48.39%316.999213,02740.0%56.3%
53.57%286.880111,95355.6%50.0%
34.62%267.077513,07720.0%43.8%
41.67%246.586514,32536.4%46.1%
50.00%226.892014,64066.7%43.8%
33.33%216.890613,95825.0%38.5%
55.56%187.180412,56544.4%66.7%
40.00%157.389813,65850.0%28.6%
38.46%136.31,21614,54716.7%57.1%
58.33%126.298212,19175.0%25.0%
50.00%127.184213,01850.0%50.0%
63.64%117.492513,84140.0%83.3%
50.00%107.31,15215,78533.3%57.1%
60.00%107.191815,02350.0%66.7%
40.00%107.188213,95950.0%33.3%
22.22%97.087713,9130.0%33.3%
66.67%97.397913,774100.0%40.0%
62.50%87.31,00712,98875.0%50.0%
28.57%76.11,04816,3150.0%28.6%
50.00%66.41,09715,68550.0%50.0%
33.33%67.176110,36950.0%0.0%
66.67%66.359410,13575.0%50.0%
0.00%55.782713,5760.0%0.0%
40.00%57.493414,15733.3%50.0%
20.00%56.77769,14025.0%0.0%
20.00%56.576110,35425.0%0.0%
40.00%54.996414,5760.0%66.7%

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Kai'Sa vs Cassiopeia - Frequently Asked Questions

How does Kai'Sa do against Cassiopeia in League of Legends?

Kai'Sa wins the Kai'Sa vs Cassiopeia matchup with a 66.7% win rate compared to Cassiopeia's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.14.

How does Kai'Sa do against Cassiopeia in the early game?

In the early game, Kai'Sa has the advantage against Cassiopeia with a 75.0% win rate versus 25.0%. Kai'Sa players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Kai'Sa do against Cassiopeia in the late game?

In the late game, Kai'Sa takes over the Kai'Sa vs Cassiopeia matchup with a 50.0% win rate compared to 50.0%. Kai'Sa scales better into team fights and objective contests after 25 minutes.

Who wins the Kai'Sa vs Cassiopeia matchup?

Kai'Sa wins the matchup against Cassiopeia with a 66.7% win rate in League of Legends patch 26.14. The 33.3 percentage point advantage means Kai'Sa is significantly favored in this lane matchup based on 6 games analyzed.

What is the best Kai'Sa build against Cassiopeia?

The best Kai'Sa build against Cassiopeia includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Kai'Sa runes against Cassiopeia?

The best Kai'Sa runes against Cassiopeia use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Kai'Sa vs Cassiopeia matchup. See the full rune breakdown in the matchup comparison above.

Does Kai'Sa counter Cassiopeia?

Yes, Kai'Sa has a favorable matchup against Cassiopeia with a 66.7% win rate. Kai'Sa strongly counters Cassiopeia in lane based on current patch 26.14 data.

How do I play Kai'Sa against Cassiopeia?

When playing Kai'Sa against Cassiopeia, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.