Kai'Sa - League of Legends Champion
Win Rate
47.7%
Pick Rate
3.8%

Kai'Savs Cassiopeia

FMarksmanMage
Patch26.10
Matches2,379,056
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 25, 2026
MethodologyData Methodology

Kai'Sa vs Cassiopeia is a very close matchup in LoL patch 26.10. Kai'Sa wins with a 50.0% win rate (+0.0%) over Cassiopeia based on 8 games. Kai'Sa holds the advantage in both the early and late game. Below you'll find the best Kai'Sa build, runes, laning stats, and strategies for the Kai'Sa vs Cassiopeia matchup.

Kai'Sa Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Kai'Sa performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Cassiopeia - 50.0% win rateCassiopeia(50.0%)
Kai'Sa - 50.0% win rate in this matchup
Kai'Sa
50.0% WR
VS
Cassiopeia vs Kai'Sa matchup - 50.0% win rate
Cassiopeia
50.0% WR

Who Wins the Kai'Sa vs Cassiopeia Matchup?

Kai'Sa wins the Kai'Sa vs Cassiopeia matchup
Winner
Kai'Sa
Matches: 8
50.0%
Win Rate
50.0%
6.9
CS / min
7.6
744
DMG / min
936
13,834
Gold / game
13,631
124
Heal / min
313
413
DMG Mitigated / min
550
0.0
CC / min
1.1
50.0%
Early Game WR
50.0%
50.0%
Late Game WR
50.0%

Kai'Sa vs Cassiopeia Matchup Summary

The Kai'Sa vs Cassiopeia matchup is essentially a coin-flip matchup in League of Legends ranked play. Based on 8 recent matches analyzed, Kai'Sa wins with a 50.0% win rate compared to Cassiopeia's 50.0%, giving Kai'Sa a 0.0 percentage point advantage. Kai'Sa holds a slight edge in both the early and late game, but the margins are thin enough that individual skill and jungle attention will often determine the outcome. Cassiopeia can still find windows through outplays and team coordination. The most significant statistical gap is in crowd control, where Cassiopeia leads by 1.1s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Kai'Sa has a statistical edge, but the margin is close enough that respecting Cassiopeia's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Kai'Sa vs Cassiopeia Laning Phase Breakdown

Cassiopeia wins the laning phase against Kai'Sa in League of Legends

Cassiopeia is favored during the laning phase against Kai'Sa, winning 4 out of 5 key stat categories. Cassiopeia holds advantages in farming, damage, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.9Kai'Sa
7.6Cassiopeia
Cassiopeia edges out Kai'Sa by 0.7 CS per minute — a moderate farming advantage that adds up to roughly 10 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Cassiopeia.
Damage
744Kai'Sa
936Cassiopeia
Cassiopeia heavily out-damages Kai'Sa by 192 DMG/min, dominating both short trades and all-in fights. Kai'Sa should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Cassiopeia's sustained damage advantage take over.
Economy
13,834Kai'Sa
13,631Cassiopeia
Kai'Sa and Cassiopeia generate nearly equal gold per game, with just a 203 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
0.0Kai'Sa
1.1Cassiopeia
Cassiopeia brings significantly more crowd control than Kai'Sa, with 1.1 more seconds of CC per minute. This large utility gap makes Cassiopeia far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Kai'Sa should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
538Kai'Sa
863Cassiopeia
Cassiopeia vastly out-sustains Kai'Sa, healing and mitigating 325 more damage per minute. This massive durability gap means Cassiopeia can absorb significant punishment and remain in lane while Kai'Sa is forced to recall. Building grievous wounds early is essential for Kai'Sa, and focusing on burst trade patterns rather than sustained fights is critical.

Best Kai'Sa Build Against Cassiopeia

Gunmetal Greaves is the optimal boots choice against Cassiopeia, providing the mobility and stats Kai'Sa needs most in this matchup. The top-performing core items for Kai'Sa against Cassiopeia are Zhonya's Hourglass, Guinsoo's Rageblade and Statikk Shiv. This combination gives Kai'Sa an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Cassiopeia. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Kai'Sa vs Cassiopeia matchup.

Early Game vs Late Game

Early Game
Kai'Sa
50.0%
+0.0% advantage
Kai'Sa early game win rateKai'Sa50.0%
Cassiopeia early game win rateCassiopeia50.0%
Late Game
Kai'Sa
50.0%
+0.0% advantage
Kai'Sa late game win rateKai'Sa50.0%
Cassiopeia late game win rateCassiopeia50.0%

The early game (first 15 minutes) is a toss-up between Kai'Sa and Cassiopeia, with Kai'Sa holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Late game (25+ minutes) is equally balanced, with Kai'Sa at 50.0% win rate — only 0.0 points ahead of Cassiopeia. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

This matchup is remarkably even at every stage of the game. Neither Kai'Sa nor Cassiopeia has a phase-specific advantage, making this a pure skill matchup where individual mechanics, decision-making, and team coordination determine the outcome.

Best Kai'Sa Runes Against Cassiopeia

Precision rune tree - Kai'Sa primary runes vs CassiopeiaPrecision
Lethal Tempo - best Kai'Sa rune vs CassiopeiaTriumph - best Kai'Sa rune vs CassiopeiaLegend: Bloodline - best Kai'Sa rune vs CassiopeiaCut Down - best Kai'Sa rune vs Cassiopeia
Inspiration rune tree - Kai'Sa secondary runes vs CassiopeiaInspiration
Cash Back - best Kai'Sa rune vs CassiopeiaTriple Tonic - best Kai'Sa rune vs Cassiopeia
100.0% WR

The Precision primary with Inspiration secondary combination helps Kai'Sa maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Cassiopeia.


Kai'Sa matchup data for League of Legends patch 26.10. The table below shows Kai'Sa's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Kai'Sa build, runes, laning stats, and early vs late game analysis for that specific matchup.

Kai'Sa matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
44.26%8886.989614,15245.5%43.4%
44.65%6366.882113,64743.9%45.2%
45.28%6256.782213,49440.1%49.7%
45.69%4996.681613,51544.1%46.9%
47.98%4966.984713,35846.0%49.6%
50.83%4807.092014,38150.5%51.1%
50.63%4806.885614,19252.8%49.1%
49.02%3066.889313,65353.9%44.8%
44.05%2276.888413,24038.7%50.5%
47.91%2156.985013,29646.1%49.6%
48.00%2006.987213,75645.6%50.0%
47.40%1926.786313,76753.7%42.7%
48.39%1866.779113,15854.6%43.0%
44.93%1386.882813,45048.5%41.4%
43.28%1347.092813,99147.6%39.4%
54.14%1336.586213,85949.2%58.3%
49.23%1306.883113,61963.0%39.5%
46.34%1236.686314,34847.1%45.8%
47.54%1226.786014,17146.0%48.6%
48.74%1196.984013,56854.4%43.5%
51.82%1107.187114,38458.0%46.7%
43.33%606.795915,09531.6%48.8%
45.76%596.688412,60752.9%36.0%
45.76%596.973512,28743.3%48.3%
48.28%586.895014,78138.1%54.0%
49.09%556.888814,69840.9%54.5%
46.94%497.093514,04442.1%50.0%
52.27%446.984115,60450.0%53.1%
39.02%416.984413,28330.4%50.0%
59.38%326.780814,98844.4%65.2%
36.67%306.381713,90227.3%42.1%
50.00%307.274813,63953.9%47.1%
58.62%296.583213,64371.4%46.7%
44.44%276.477613,45840.0%47.1%
34.62%266.51,01212,35041.7%28.6%
50.00%266.084712,87860.0%43.8%
40.00%256.482013,87816.7%47.4%
37.50%246.689816,32533.3%40.0%
54.17%247.094115,49133.3%61.1%
31.82%227.11,03114,21418.2%45.5%
35.29%177.083713,44514.3%50.0%
47.06%177.176412,87144.4%50.0%
50.00%166.287512,64740.0%54.5%
46.67%157.090412,00541.7%66.7%
21.43%146.878212,54933.3%12.5%
28.57%146.773612,00316.7%37.5%
38.46%136.91,09414,71628.6%50.0%
27.27%115.973413,73633.3%25.0%
45.45%117.297615,11666.7%37.5%
80.00%106.692514,575100.0%66.7%
50.00%106.999314,64050.0%50.0%
50.00%106.982612,10037.5%100.0%
30.00%106.964613,48725.0%33.3%
55.56%96.195411,07583.3%0.0%
55.56%96.390815,07375.0%40.0%
33.33%96.987712,91725.0%40.0%
44.44%96.584213,88833.3%50.0%
55.56%97.090413,57566.7%50.0%
37.50%86.583014,0920.0%42.9%
50.00%86.974413,83450.0%50.0%
42.86%76.984714,6260.0%60.0%
57.14%73.867014,30033.3%75.0%
14.29%75.772210,4840.0%33.3%
42.86%76.291712,80466.7%25.0%
0.00%66.562310,5340.0%0.0%
66.67%67.398514,73433.3%100.0%
50.00%67.194212,20733.3%66.7%
50.00%67.01,02513,8440.0%100.0%
0.00%66.583811,7180.0%0.0%
50.00%64.982312,7330.0%75.0%
50.00%66.382410,72333.3%66.7%
66.67%66.881912,88450.0%75.0%
40.00%56.590414,6450.0%50.0%
40.00%56.41,12816,631100.0%25.0%
20.00%56.997914,5780.0%20.0%
60.00%57.269414,25666.7%50.0%
60.00%56.668212,47350.0%66.7%
40.00%55.491014,61450.0%33.3%
80.00%55.91,14417,0910.0%80.0%
0.00%57.483512,6680.0%0.0%
60.00%56.01,08015,410100.0%50.0%
40.00%57.91,14213,26850.0%33.3%

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Kai'Sa vs Cassiopeia - Frequently Asked Questions

How does Kai'Sa do against Cassiopeia in League of Legends?

Kai'Sa wins the Kai'Sa vs Cassiopeia matchup with a 50.0% win rate compared to Cassiopeia's 50.0%, a 0.0 percentage point difference. This data is based on 8 recent ranked games in patch 26.10.

How does Kai'Sa do against Cassiopeia in the early game?

In the early game, Kai'Sa has the advantage against Cassiopeia with a 50.0% win rate versus 50.0%. Kai'Sa players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Kai'Sa do against Cassiopeia in the late game?

In the late game, Kai'Sa takes over the Kai'Sa vs Cassiopeia matchup with a 50.0% win rate compared to 50.0%. Kai'Sa scales better into team fights and objective contests after 25 minutes.

Who wins the Kai'Sa vs Cassiopeia matchup?

Kai'Sa wins the matchup against Cassiopeia with a 50.0% win rate in League of Legends patch 26.10. The 0.0 percentage point advantage means Kai'Sa is slightly favored in this lane matchup based on 8 games analyzed.

What is the best Kai'Sa build against Cassiopeia?

The best Kai'Sa build against Cassiopeia includes Zhonya's Hourglass, Guinsoo's Rageblade, Statikk Shiv with Gunmetal Greaves. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Kai'Sa runes against Cassiopeia?

The best Kai'Sa runes against Cassiopeia use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Kai'Sa vs Cassiopeia matchup. See the full rune breakdown in the matchup comparison above.

Does Kai'Sa counter Cassiopeia?

Yes, Kai'Sa has a favorable matchup against Cassiopeia with a 50.0% win rate. Kai'Sa slightly edges out Cassiopeia in lane based on current patch 26.10 data.

How do I play Kai'Sa against Cassiopeia?

When playing Kai'Sa against Cassiopeia, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.