Kha'Zix, League of Legends champion
Win Rate
48.2%
Pick Rate
2.8%
Ban Rate
2.5%

Kha'Zixvs Karthus

Kha'Zix F TierAssassin
Patch26.19
Games2,519
LaneAll Lanes
TierAll Tiers
Last UpdatedOct 3, 2026 UTC
MethodologyData Methodology

Kha'Zix vs Karthus is a moderate matchup in LoL patch 26.19. Kha'Zix wins with a 52.2% win rate (+4.3%) over Karthus based on 23 games. Kha'Zix holds the advantage in both the early and late game. Below you'll find the best Kha'Zix build, runes, laning stats, and strategies for the Kha'Zix vs Karthus matchup.

Kha'Zix Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Kha'Zix performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Kha'Zix
Kha'Zix
47.1%
VS
Karthus
52.9%
Karthus

Who wins Kha'Zix vs Karthus?

Slight Karthus edgeLow confidence

Kha'Zix wins 47.1% of these games. With this many games the true rate is most likely between 31.5% and 63.3% (95% range).

Expected
49.9%
From both champions' overall Jungle win rates
Matchup effect
−2.9 pts
Observed minus expected
Sample
34 games
Lane: Jungle
vs patch 26.18
—
Not enough games on both patches

Lane: Jungle · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.19 · Sep 24 – Sep 28

Key takeaways

  • Current data slightly favors Karthus, but the sample is too limited for a strong conclusion: Kha'Zix wins 47.1% of 34 games (95% range 31.5–63.3%).
  • Both champions' overall Jungle win rates predict 49.9% for Kha'Zix; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
  • Neither side reliably wins the lane: the average gold difference at 15 minutes is 235, within the margin of error (32 games).
  • Kha'Zix players pick Voltaic Cyclosword much less often against Karthus: 72.4% of their other Jungle games, 52.9% here.
How we calculate this

Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.

A game only counts when Kha'Zix and Karthus played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.

The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.

Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.

"What changes" compares Kha'Zix's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).

Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.

Kha'Zix vs Karthus Laning Stats

Kha'ZixKarthus

At 15 minutes

Gold difference
+235
Within the margin of error
95% range −224 to +694
XP difference
−363
Within the margin of error
95% range −822 to +96
CS difference
−13.8
Karthus ahead
95% range −19.9 to −7.6
4.28
Kills before 15 min
2.69
2.22
Deaths before 15 min
2.84
1.00
Solo kills before 15 min
0.32
5.9%
First blood
2.9%

Whole-game averages

0.8
CS / min
1.4
698
DMG / min
1,136
13,778
Gold / game
13,912
443
Heal / min
286
632
DMG Mitigated / min
458
0.3
CC / min
0.5

Kha'Zix vs Karthus Win Rate by Game Length

Kha'Zix's win rate against Karthus by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.

Too few games
Under 20 min
4 games
Too few games
20–25 min
3 games
Too few games
25–30 min
8 games
Too few games
30–35 min
9 games
Too few games
35+ min
10 games
Kha'Zix vs Karthus95% rangeKha'Zix usual (Jungle)

No game length stands out: Kha'Zix's results against Karthus in short and long games are within the margin of error of each other.

Kha'Zix vs Karthus Power Spikes

Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.

  1. Lane (15 min)EvenKha'Zix gold at 15: +235
  2. First itemInsufficient data
  3. Games under 20 minInsufficient data
  4. 20–30 min gamesInsufficient data
  5. 30+ min gamesInsufficient data

What Kha'Zix Changes Against Karthus

Choices Kha'Zix players make noticeably more or less often in this matchup than in their other Jungle games.

Best Kha'Zix Build vs Karthus

Usual Kha'Zix build (Jungle)

74.1% win rate · 27 games

Against Karthus

Not enough matchup-specific build data: only 4 of 24 Kha'Zix games against Karthus carried a complete build, which is too few to recommend an item path from. Use Kha'Zix's standard build instead.

  • Karthus usually completes Scorchclaw Pup first, at 0.2 min (median of 25 games).
  • Skill priority: Q > W > E — the same as usual.

Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.

Best Kha'Zix Runes vs Karthus

Usual Kha'Zix runes (Jungle)

First StrikeFirst Strike
Inspiration
Cash BackTriple TonicCosmic Insight
Domination
Sudden ImpactTreasure Hunter
Adaptive Force (offense)Adaptive Force (flex)Health Scaling (defense)

50.3% win rate · 1,787 games

Against Karthus

Too few games for a matchup-specific rune page yet — use the usual page.

MetaBot Desktop

Plan your Kha'Zix draft in Draft Lab

Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.

  • Full 5v5 draft board
  • Lane matchup win rates
  • Pick and ban suggestions
Draft Lab in MetaBot Desktop

Kha'Zix matchup data for League of Legends patch 26.19. The table below shows Kha'Zix's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Kha'Zix build, runes, laning stats, and early vs late game analysis for that specific matchup.

Other Kha'Zix Matchups

Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.

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Kha'Zix vs Karthus FAQ - Patch 26.19

Who wins Kha'Zix vs Karthus?

Current data slightly favors Karthus, but the sample is too limited for a strong conclusion: Kha'Zix wins 47.1% of 34 games (95% range 31.5–63.3%).

What is Kha'Zix's win rate against Karthus?

Kha'Zix wins 47.1% of 34 Jungle games against Karthus on patch 26.19 (95% range 31.5–63.3%). Based on both champions' overall Jungle win rates, 49.9% would be expected.

Does Kha'Zix counter Karthus?

Not clearly. Kha'Zix wins 47.1% of 34 games against Karthus, and the 95% range (31.5–63.3%) includes 50%, so neither champion reliably counters the other on current data.

Who wins lane, Kha'Zix or Karthus?

Neither side reliably wins the lane: the average gold difference at 15 minutes is 235, within the margin of error (32 games).

Does Kha'Zix outscale Karthus?

There are too few games of each length to tell yet.

When is Karthus strongest against Kha'Zix?

On current data there is no stage of the game where Karthus is ahead of Kha'Zix beyond the margin of error.

What should Kha'Zix build against Karthus?

There are not enough games for a matchup-specific core, so use Kha'Zix's usual Jungle core: Serpent's Fang, Serylda's Grudge, Edge of Night. The biggest change against Karthus: Voltaic Cyclosword (72.4% usually, 52.9% here).

What runes should Kha'Zix use against Karthus?

Use Kha'Zix's usual First Strike page (Inspiration + Domination); there are too few games for a matchup-specific page. The biggest change against Karthus: Celerity (2.0% usually, 11.8% here).