
Karthusvs Kha'Zix
Karthus vs Kha'Zix is a moderate matchup in LoL patch 26.19. Kha'Zix wins with a 52.2% win rate (+4.3%) over Karthus based on 23 games. Karthus wins the early laning phase while Kha'Zix scales better into the late game. Below you'll find the best Karthus build, runes, laning stats, and strategies for the Karthus vs Kha'Zix matchup.
Karthus Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Karthus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.


Who wins Karthus vs Kha'Zix?
Karthus wins 52.9% of these games. With this many games the true rate is most likely between 36.7% and 68.5% (95% range).
- Expected
- 50.1% From both champions' overall Jungle win rates
- Matchup effect
- +2.9 pts Observed minus expected
- Sample
- 34 games Lane: Jungle
- vs patch 26.18
- — Not enough games on both patches
Lane: Jungle · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.19 · Sep 24 – Sep 28
Key takeaways
- Current data slightly favors Karthus, but the sample is too limited for a strong conclusion: Karthus wins 52.9% of 34 games (95% range 36.7–68.5%).
- Both champions' overall Jungle win rates predict 50.1% for Karthus; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
- Neither side reliably wins the lane: the average gold difference at 15 minutes is 235, within the margin of error (32 games).
- Karthus players pick Ability Haste (offense) far more often against Kha'Zix: 5.6% of their other Jungle games, 20.6% here.
How we calculate this
Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.
A game only counts when Karthus and Kha'Zix played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.
The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.
Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.
"What changes" compares Karthus's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).
Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.
Karthus vs Kha'Zix Laning Stats
At 15 minutes
Whole-game averages
Karthus vs Kha'Zix Win Rate by Game Length
Karthus's win rate against Kha'Zix by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.
No game length stands out: Karthus's results against Kha'Zix in short and long games are within the margin of error of each other.
Karthus vs Kha'Zix Power Spikes
Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.
- Lane (15 min)EvenKarthus gold at 15: −235
- First itemInsufficient data
- Games under 20 minInsufficient data
- 20–30 min gamesInsufficient data
- 30+ min gamesInsufficient data
What Karthus Changes Against Kha'Zix
Choices Karthus players make noticeably more or less often in this matchup than in their other Jungle games.
Ability Haste (offense)Stat shardUsually5.6%vs Kha'Zix20.6%+15.0 pts
Adaptive Force (offense)Stat shardUsually93.5%vs Kha'Zix79.4%−14.1 pts51.9% WR here
DominationSecondary treeUsually3.0%vs Kha'Zix11.8%+8.7 pts
Legend: HasteRuneUsually1.2%vs Kha'Zix8.8%+7.7 pts
CryptbloomItemUsually1.3%vs Kha'Zix5.9%+4.6 pts
Best Karthus Build vs Kha'Zix
Usual Karthus build (Jungle)
71.1% win rate · 38 games
Against Kha'Zix
Not enough matchup-specific build data: only 2 of 23 Karthus games against Kha'Zix carried a complete build, which is too few to recommend an item path from. Use Karthus's standard build instead.
- Karthus usually completes Scorchclaw Pup first, at 0.2 min (median of 25 games).
- Skill priority: Q > E > W — the same as usual.
Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.
Best Karthus Runes vs Kha'Zix
Plan your Karthus draft in Draft Lab
Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.
- Full 5v5 draft board
- Lane matchup win rates
- Pick and ban suggestions

Karthus matchup data for League of Legends patch 26.19. The table below shows Karthus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karthus build, runes, laning stats, and early vs late game analysis for that specific matchup.
Other Karthus Matchups
Hardest for Karthus
Easiest for Karthus
Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Karthus vs Kha'Zix FAQ - Patch 26.19
Who wins Karthus vs Kha'Zix?
Current data slightly favors Karthus, but the sample is too limited for a strong conclusion: Karthus wins 52.9% of 34 games (95% range 36.7–68.5%).
What is Karthus's win rate against Kha'Zix?
Karthus wins 52.9% of 34 Jungle games against Kha'Zix on patch 26.19 (95% range 36.7–68.5%). Based on both champions' overall Jungle win rates, 50.1% would be expected.
Does Karthus counter Kha'Zix?
Not clearly. Karthus wins 52.9% of 34 games against Kha'Zix, and the 95% range (36.7–68.5%) includes 50%, so neither champion reliably counters the other on current data.
Who wins lane, Karthus or Kha'Zix?
Neither side reliably wins the lane: the average gold difference at 15 minutes is 235, within the margin of error (32 games).
Does Karthus outscale Kha'Zix?
There are too few games of each length to tell yet.
When is Kha'Zix strongest against Karthus?
On current data there is no stage of the game where Kha'Zix is ahead of Karthus beyond the margin of error.
What should Karthus build against Kha'Zix?
There are not enough games for a matchup-specific core, so use Karthus's usual Jungle core: Liandry's Torment, Stormsurge, Shadowflame. The biggest change against Kha'Zix: Cryptbloom (1.3% usually, 5.9% here).
What runes should Karthus use against Kha'Zix?
Use Karthus's usual Deathfire Touch page (Sorcery + Precision); there are too few games for a matchup-specific page. The biggest change against Kha'Zix: Ability Haste (offense) (5.6% usually, 20.6% here).
