Lillia - League of Legends Champion
Win Rate
50.3%
Pick Rate
1.5%

Lilliavs Karthus

BFighterMage
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 22, 2026
MethodologyData Methodology

Lillia vs Karthus is a decisive matchup in LoL patch 26.14. Lillia wins with a 54.5% win rate (+9.1%) over Karthus based on 11 games. Karthus wins the early laning phase while Lillia scales better into the late game. Below you'll find the best Lillia build, runes, laning stats, and strategies for the Lillia vs Karthus matchup.

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Lillia Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lillia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lillia - 54.5% win rate in this matchup
Lillia
54.5% WR
VS
Karthus vs Lillia matchup - 45.5% win rate
Karthus
45.5% WR

Who Wins the Lillia vs Karthus Matchup?

Lillia wins the Lillia vs Karthus matchup
Winner
Lillia
Matches: 11
54.5%
Win Rate
45.5%
1.2
CS / min
1.3
875
DMG / min
1,270
13,216
Gold / game
13,006
782
Heal / min
272
904
DMG Mitigated / min
461
0.9
CC / min
0.7
33.3%
Early Game WR
66.7%
62.5%
Late Game WR
37.5%

Lillia vs Karthus Matchup Summary

The Lillia vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 11 recent matches analyzed, Lillia wins with a 54.5% win rate compared to Karthus's 45.5%, giving Lillia a 9.1 percentage point advantage. Game phase dynamics play a critical role here: Karthus controls the early laning stage, but Lillia outscales as the game goes longer. The matchup shifts dramatically depending on game length — Karthus needs to press advantages before Lillia reaches their power spikes, while Lillia should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Lillia leads by 953 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Lillia players can confidently pick into Karthus and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Karthus away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lillia vs Karthus Laning Phase Breakdown

Lillia wins the laning phase against Karthus in League of Legends

Lillia is favored during the laning phase against Karthus, winning 3 out of 5 key stat categories. Lillia holds advantages in gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
1.2Lillia
1.3Karthus
Lillia and Karthus farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
875Lillia
1,270Karthus
Karthus heavily out-damages Lillia by 395 DMG/min, dominating both short trades and all-in fights. Lillia should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
13,216Lillia
13,006Karthus
Lillia and Karthus generate nearly equal gold per game, with just a 210 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
0.9Lillia
0.7Karthus
Both Lillia and Karthus provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
1,686Lillia
733Karthus
Lillia vastly out-sustains Karthus, healing and mitigating 953 more damage per minute. This massive durability gap means Lillia can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Lillia Build Against Karthus

Sorcerer's Shoes is the optimal boots choice against Karthus, providing the mobility and stats Lillia needs most in this matchup. The top-performing core items for Lillia against Karthus are Liandry's Torment, Riftmaker and Zhonya's Hourglass. This combination gives Lillia an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 66.7% win rate across 3 games — well above average and making it the top item path against Karthus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lillia vs Karthus matchup.

Early Game vs Late Game

Early Game
Karthus
66.7%
+33.3% advantage
Lillia early game win rateLillia33.3%
Karthus early game win rateKarthus66.7%
Late Game
Lillia
62.5%
+25.0% advantage
Lillia late game win rateLillia62.5%
Karthus late game win rateKarthus37.5%

Karthus dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Lillia. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Lillia is far superior in the late game (25+ minutes), boasting a 62.5% win rate — 25.0 points above Karthus. Extended games heavily favor Lillia, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Karthus must aggressively press their early advantage and close out the game before Lillia reaches their scaling breakpoints. If Lillia survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Lillia Runes Against Karthus

Precision rune tree - Lillia primary runes vs KarthusPrecision
Conqueror - best Lillia rune vs KarthusTriumph - best Lillia rune vs KarthusLegend: Haste - best Lillia rune vs KarthusCoup de Grace - best Lillia rune vs Karthus
Inspiration rune tree - Lillia secondary runes vs KarthusInspiration
Cosmic Insight - best Lillia rune vs KarthusMagical Footwear - best Lillia rune vs Karthus
40.0% WR

Running Precision primary with Inspiration secondary allows Lillia to press their advantage against Karthus, amplifying the strengths that make this a favorable matchup.


Lillia matchup data for League of Legends patch 26.14. The table below shows Lillia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lillia build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lillia matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.41%851.274511,74253.3%47.3%
46.77%621.278612,49430.0%54.8%
46.67%601.470311,86538.5%52.9%
40.68%591.476513,43928.6%44.4%
47.37%571.167911,59247.6%47.2%
62.26%531.375412,07963.6%61.3%
40.82%491.280512,91044.4%38.7%
55.56%451.286312,95241.2%64.3%
53.33%451.265112,58254.5%52.9%
58.54%411.267111,65142.1%72.7%
43.59%391.172611,40335.3%50.0%
55.26%381.066511,06738.9%70.0%
66.67%361.380812,91875.0%62.5%
57.14%351.275811,42562.5%52.6%
56.25%321.485411,97864.3%50.0%
51.61%310.977713,26853.9%50.0%
51.61%311.289413,21333.3%56.0%
56.67%302.078612,17554.5%57.9%
46.43%281.387111,52633.3%56.3%
57.14%281.487112,37063.6%52.9%
52.00%251.51,00213,90487.5%35.3%
40.00%251.280912,35712.5%52.9%
41.67%241.180712,50342.9%41.2%
54.17%241.374610,99754.5%53.9%
65.22%231.069310,66653.3%87.5%
52.17%231.263612,87344.4%57.1%
65.00%201.273012,37466.7%64.3%
63.16%191.288812,22975.0%54.5%
55.56%181.380813,186100.0%38.5%
41.18%171.271312,34450.0%36.4%
64.71%171.286412,53237.5%88.9%
35.29%171.372712,42742.9%30.0%
66.67%152.485814,06180.0%60.0%
40.00%151.183312,78728.6%50.0%
60.00%151.71,17713,95680.0%50.0%
50.00%140.970510,06571.4%28.6%
71.43%141.373112,54340.0%88.9%
45.45%111.281812,9620.0%55.6%
45.45%111.577411,59420.0%66.7%
18.18%111.16439,69133.3%0.0%
54.55%111.287513,21633.3%62.5%
50.00%101.373310,52960.0%40.0%
70.00%101.287112,21340.0%100.0%
20.00%101.31,02611,4280.0%33.3%
10.00%103.375210,98925.0%0.0%
40.00%101.279910,21750.0%33.3%
62.50%81.91,09212,01966.7%60.0%
62.50%81.684914,31450.0%66.7%
37.50%82.085611,94650.0%33.3%
50.00%81.192914,23366.7%40.0%
37.50%81.14669,90442.9%0.0%
28.57%71.681613,469100.0%16.7%
42.86%72.472810,57666.7%25.0%
85.71%71.396812,560100.0%75.0%
14.29%71.976814,2790.0%20.0%
66.67%61.278313,671100.0%60.0%
66.67%61.357611,267100.0%33.3%
50.00%62.896712,08966.7%33.3%
80.00%52.994213,181100.0%75.0%
60.00%51.84135,97833.3%100.0%
0.00%50.946710,1370.0%0.0%
60.00%50.95008,09675.0%0.0%

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Lillia vs Karthus - Frequently Asked Questions

How does Lillia do against Karthus in League of Legends?

Lillia wins the Lillia vs Karthus matchup with a 54.5% win rate compared to Karthus's 45.5%, a 9.1 percentage point difference. This data is based on 11 recent ranked games in patch 26.14.

How does Lillia do against Karthus in the early game?

In the early game, Karthus has the advantage against Lillia with a 66.7% win rate versus 33.3%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lillia do against Karthus in the late game?

In the late game, Lillia takes over the Lillia vs Karthus matchup with a 62.5% win rate compared to 37.5%. Lillia scales better into team fights and objective contests after 25 minutes.

Who wins the Lillia vs Karthus matchup?

Lillia wins the matchup against Karthus with a 54.5% win rate in League of Legends patch 26.14. The 9.1 percentage point advantage means Lillia is significantly favored in this lane matchup based on 11 games analyzed.

What is the best Lillia build against Karthus?

The best Lillia build against Karthus includes Liandry's Torment, Riftmaker, Zhonya's Hourglass with Sorcerer's Shoes. This build achieves a 66.7% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Lillia runes against Karthus?

The best Lillia runes against Karthus use the Precision primary tree with Inspiration secondary. This rune setup achieves a 40.0% win rate in the Lillia vs Karthus matchup. See the full rune breakdown in the matchup comparison above.

Does Lillia counter Karthus?

Yes, Lillia has a favorable matchup against Karthus with a 54.5% win rate. Lillia strongly counters Karthus in lane based on current patch 26.14 data.

How do I play Lillia against Karthus?

When playing Lillia against Karthus, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Karthus. Build the recommended items and runes for this specific matchup for the best results.