Lillia - League of Legends Champion
Win Rate
50.3%
Pick Rate
1.6%

Lilliavs Karthus

BFighterMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 22, 2026
MethodologyData Methodology

Lillia vs Karthus is a decisive matchup in LoL patch 26.7. Lillia wins with a 72.7% win rate (+45.5%) over Karthus based on 11 games. Lillia holds the advantage in both the early and late game. Below you'll find the best Lillia build, runes, laning stats, and strategies for the Lillia vs Karthus matchup.

Lillia Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lillia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karthus - 72.7% win rateKarthus(72.7%)
Lillia - 72.7% win rate in this matchup
Lillia
72.7% WR
VS
Karthus vs Lillia matchup - 27.3% win rate
Karthus
27.3% WR

Who Wins the Lillia vs Karthus Matchup?

Lillia wins the Lillia vs Karthus matchup
Winner
Lillia
Matches: 11
72.7%
Win Rate
27.3%
1.2
CS / min
1.3
818
DMG / min
1,125
12,425
Gold / game
12,250
724
Heal / min
296
721
DMG Mitigated / min
507
0.9
CC / min
0.7
80.0%
Early Game WR
20.0%
66.7%
Late Game WR
33.3%

Lillia vs Karthus Matchup Summary

The Lillia vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 11 recent matches analyzed, Lillia wins with a 72.7% win rate compared to Karthus's 27.3%, giving Lillia a 45.5 percentage point advantage. Lillia dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Karthus players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Lillia leads by 643 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Lillia players can confidently pick into Karthus and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Karthus away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lillia vs Karthus Laning Phase Breakdown

Lillia wins the laning phase against Karthus in League of Legends

Lillia is favored during the laning phase against Karthus, winning 3 out of 5 key stat categories. Lillia holds advantages in gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
1.2Lillia
1.3Karthus
Lillia and Karthus farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
818Lillia
1,125Karthus
Karthus heavily out-damages Lillia by 307 DMG/min, dominating both short trades and all-in fights. Lillia should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
12,425Lillia
12,250Karthus
Lillia and Karthus generate nearly equal gold per game, with just a 175 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
0.9Lillia
0.7Karthus
Both Lillia and Karthus provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
1,445Lillia
803Karthus
Lillia vastly out-sustains Karthus, healing and mitigating 643 more damage per minute. This massive durability gap means Lillia can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Lillia Build Against Karthus

Ionian Boots of Lucidity is the optimal boots choice against Karthus, providing the mobility and stats Lillia needs most in this matchup. The top-performing core items for Lillia against Karthus are Liandry's Torment, Riftmaker and Zhonya's Hourglass. This combination gives Lillia an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 66.7% win rate across 3 games — well above average and making it the top item path against Karthus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lillia vs Karthus matchup.

Early Game vs Late Game

Early Game
Lillia
80.0%
+60.0% advantage
Lillia early game win rateLillia80.0%
Karthus early game win rateKarthus20.0%
Late Game
Lillia
66.7%
+33.3% advantage
Lillia late game win rateLillia66.7%
Karthus late game win rateKarthus33.3%

Lillia dominates the early game (first 15 minutes) with a commanding 80.0% win rate — a 60.0 percentage point lead over Karthus. This lopsided early game means Lillia can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Lillia is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Karthus. Extended games heavily favor Lillia, whose kit and scaling make them a dominant force in team fights and objective control.

Lillia holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Karthus players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Lillia Runes Against Karthus

Precision rune tree - Lillia primary runes vs KarthusPrecision
Conqueror - best Lillia rune vs KarthusTriumph - best Lillia rune vs KarthusLegend: Haste - best Lillia rune vs KarthusCoup de Grace - best Lillia rune vs Karthus
Sorcery rune tree - Lillia secondary runes vs KarthusSorcery
Celerity - best Lillia rune vs KarthusWaterwalking - best Lillia rune vs Karthus
100.0% WR

Running Precision primary with Sorcery secondary allows Lillia to press their advantage against Karthus, amplifying the strengths that make this a favorable matchup.


Lillia matchup data for League of Legends patch 26.7. The table below shows Lillia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lillia build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lillia matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
42.86%981.280312,56646.0%41.0%
40.96%831.270512,65840.0%41.7%
42.50%801.276313,27055.9%32.6%
55.84%771.378412,28660.5%51.3%
50.70%711.278312,29745.0%58.1%
47.14%701.381813,11046.9%47.4%
48.28%581.375113,17647.8%48.6%
36.96%461.387113,60553.3%29.0%
42.22%451.076211,85533.3%52.4%
72.73%441.290213,79777.8%69.2%
58.14%431.280212,87850.0%65.2%
58.97%391.484412,91352.9%63.6%
55.26%381.41,03812,01752.4%58.8%
48.48%331.372712,24835.3%62.5%
44.83%291.386214,49033.3%50.0%
62.07%291.277812,12253.3%71.4%
44.83%291.378112,78827.3%55.6%
65.52%291.075711,47563.2%70.0%
53.57%281.279813,49850.0%55.6%
42.86%281.275512,88140.0%44.4%
22.22%271.164511,86527.3%18.8%
34.62%261.066610,86335.7%33.3%
69.23%261.895312,99054.5%80.0%
61.54%261.576412,64050.0%71.4%
34.62%261.381612,76758.3%14.3%
66.67%241.377615,04360.0%68.4%
28.57%211.390213,46814.3%35.7%
60.00%201.294513,75850.0%66.7%
55.00%201.075711,98560.0%50.0%
47.37%191.580111,97337.5%54.5%
42.11%191.179412,53837.5%45.5%
33.33%181.278612,29745.5%14.3%
41.18%171.388613,32428.6%50.0%
35.29%171.271712,18566.7%18.2%
56.25%161.092111,62950.0%62.5%
43.75%161.394813,98040.0%45.5%
60.00%151.975911,05450.0%71.4%
61.54%131.366711,22133.3%85.7%
46.15%131.38129,97471.4%16.7%
61.54%131.383712,16050.0%80.0%
38.46%131.155911,84916.7%57.1%
23.08%132.467410,7090.0%42.9%
66.67%124.480211,26183.3%50.0%
50.00%121.370412,71375.0%37.5%
54.55%111.584214,1910.0%60.0%
54.55%110.77879,97842.9%75.0%
36.36%111.974012,15940.0%33.3%
72.73%111.281812,42580.0%66.7%
60.00%102.376010,16466.7%50.0%
70.00%101.893413,97860.0%80.0%
50.00%101.594113,29375.0%33.3%
70.00%102.490113,78275.0%66.7%
66.67%91.075613,51275.0%60.0%
50.00%81.387813,603100.0%33.3%
62.50%81.45699,38466.7%50.0%
71.43%73.11,34215,91650.0%80.0%
50.00%63.990112,66566.7%33.3%
66.67%61.276612,05966.7%66.7%
66.67%64.71,31215,18450.0%75.0%
83.33%61.097312,78366.7%100.0%
60.00%54.480112,90250.0%66.7%
20.00%51.062711,2350.0%33.3%
60.00%51.268111,98075.0%0.0%

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Lillia vs Karthus - Frequently Asked Questions

How does Lillia do against Karthus in League of Legends?

Lillia wins the Lillia vs Karthus matchup with a 72.7% win rate compared to Karthus's 27.3%, a 45.5 percentage point difference. This data is based on 11 recent ranked games in patch 26.7.

How does Lillia do against Karthus in the early game?

In the early game, Lillia has the advantage against Karthus with a 80.0% win rate versus 20.0%. Lillia players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lillia do against Karthus in the late game?

In the late game, Lillia takes over the Lillia vs Karthus matchup with a 66.7% win rate compared to 33.3%. Lillia scales better into team fights and objective contests after 25 minutes.

Who wins the Lillia vs Karthus matchup?

Lillia wins the matchup against Karthus with a 72.7% win rate in League of Legends patch 26.7. The 45.5 percentage point advantage means Lillia is significantly favored in this lane matchup based on 11 games analyzed.

What is the best Lillia build against Karthus?

The best Lillia build against Karthus includes Liandry's Torment, Riftmaker, Zhonya's Hourglass with Ionian Boots of Lucidity. This build achieves a 66.7% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Lillia runes against Karthus?

The best Lillia runes against Karthus use the Precision primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Lillia vs Karthus matchup. See the full rune breakdown in the matchup comparison above.

Does Lillia counter Karthus?

Yes, Lillia has a favorable matchup against Karthus with a 72.7% win rate. Lillia strongly counters Karthus in lane based on current patch 26.7 data.

How do I play Lillia against Karthus?

When playing Lillia against Karthus, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.