Lillia - League of Legends Champion
Win Rate
50.9%
Pick Rate
1.7%

Lilliavs Karthus

AFighterMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 7, 2026
MethodologyData Methodology

Lillia vs Karthus is a decisive matchup in LoL patch 26.11. Karthus wins with a 72.7% win rate (+45.5%) over Lillia based on 11 games. Karthus holds the advantage in both the early and late game. Below you'll find the best Lillia build, runes, laning stats, and strategies for the Lillia vs Karthus matchup.

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Lillia Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lillia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lillia - 27.3% win rate in this matchup
Lillia
27.3% WR
VS
Karthus vs Lillia matchup - 72.7% win rate
Karthus
72.7% WR

Who Wins the Lillia vs Karthus Matchup?

Karthus wins the Lillia vs Karthus matchup
Winner
Karthus
Matches: 11
27.3%
Win Rate
72.7%
1.5
CS / min
1.6
727
DMG / min
1,027
12,300
Gold / game
12,997
622
Heal / min
302
684
DMG Mitigated / min
427
0.8
CC / min
0.6
0.0%
Early Game WR
100.0%
42.9%
Late Game WR
57.1%

Lillia vs Karthus Matchup Summary

The Lillia vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 11 recent matches analyzed, Karthus wins with a 72.7% win rate compared to Lillia's 27.3%, giving Karthus a 45.5 percentage point advantage. Karthus dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Lillia players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Lillia leads by 577 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Karthus has a strong advantage in this matchup. Lillia players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Karthus overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lillia vs Karthus Laning Phase Breakdown

Karthus wins the laning phase against Lillia in League of Legends

Karthus is favored during the laning phase against Lillia, winning 3 out of 5 key stat categories. Karthus holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
1.5Lillia
1.6Karthus
Lillia and Karthus farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
727Lillia
1,027Karthus
Karthus heavily out-damages Lillia by 300 DMG/min, dominating both short trades and all-in fights. Lillia should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
12,300Lillia
12,997Karthus
Karthus earns 697 more gold per game than Lillia, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Karthus slightly faster item completions.
Utility
0.8Lillia
0.6Karthus
Both Lillia and Karthus provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
1,305Lillia
728Karthus
Lillia vastly out-sustains Karthus, healing and mitigating 577 more damage per minute. This massive durability gap means Lillia can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Lillia Build Against Karthus

Sorcerer's Shoes is the optimal boots choice against Karthus, providing the mobility and stats Lillia needs most in this matchup. The top-performing core items for Lillia against Karthus are Liandry's Torment, Riftmaker and Zhonya's Hourglass. This combination gives Lillia an effective balance of damage, survivability, and utility for the matchup. This build has a 25.0% win rate across 4 games. While the overall matchup may be difficult, this item path gives Lillia the best chance to compete against Karthus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lillia vs Karthus matchup.

Early Game vs Late Game

Early Game
Karthus
100.0%
+100.0% advantage
Lillia early game win rateLillia0.0%
Karthus early game win rateKarthus100.0%
Late Game
Karthus
57.1%
+14.3% advantage
Lillia late game win rateLillia42.9%
Karthus late game win rateKarthus57.1%

Karthus dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Lillia. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Karthus is far superior in the late game (25+ minutes), boasting a 57.1% win rate — 14.3 points above Lillia. Extended games heavily favor Karthus, whose kit and scaling make them a dominant force in team fights and objective control.

Karthus holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Lillia players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Lillia Runes Against Karthus

Precision rune tree - Lillia primary runes vs KarthusPrecision
Conqueror - best Lillia rune vs KarthusTriumph - best Lillia rune vs KarthusLegend: Haste - best Lillia rune vs KarthusCoup de Grace - best Lillia rune vs Karthus
Inspiration rune tree - Lillia secondary runes vs KarthusInspiration
Magical Footwear - best Lillia rune vs KarthusCosmic Insight - best Lillia rune vs Karthus
50.0% WR

The Precision and Inspiration rune setup gives Lillia the best tools to compete against Karthus in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Lillia matchup data for League of Legends patch 26.11. The table below shows Lillia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lillia build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lillia matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.17%1201.274712,69051.1%48.0%
39.66%1161.175712,65425.0%47.4%
38.68%1061.485512,71233.3%42.2%
50.52%971.383312,99758.8%46.0%
52.58%971.284512,82359.5%47.3%
57.78%901.267412,14960.9%54.5%
44.32%881.267211,91747.6%41.3%
46.15%781.478712,82960.0%34.9%
48.05%771.273512,45648.6%47.5%
52.86%701.178313,04960.0%48.9%
59.09%661.384613,23855.2%62.2%
44.44%631.477612,42844.0%44.7%
60.66%611.186712,23866.7%53.6%
53.45%581.483612,24559.3%48.4%
51.85%541.076013,08441.2%56.8%
44.00%501.578812,27043.5%44.4%
53.06%491.590113,07141.7%64.0%
48.94%471.469811,34343.5%54.2%
53.19%471.072311,18050.0%56.5%
46.81%471.387012,72250.0%44.0%
48.94%471.168912,29255.0%44.4%
52.27%441.169912,74860.0%48.3%
47.73%441.577013,86338.5%51.6%
65.00%401.471510,60065.2%64.7%
51.28%391.376913,29250.0%52.6%
55.56%361.173712,33957.9%52.9%
57.58%331.194612,07438.5%70.0%
54.55%331.177411,99841.2%68.8%
56.67%301.393814,50037.5%63.6%
43.33%301.279212,22640.0%46.7%
46.67%301.367511,55633.3%60.0%
34.48%291.276413,57718.2%44.4%
50.00%261.376612,14258.3%42.9%
52.00%251.467113,05937.5%58.8%
62.50%241.063411,19452.9%85.7%
52.63%191.277912,72855.6%50.0%
63.16%192.51,05012,38055.6%70.0%
83.33%181.080912,66577.8%88.9%
47.06%172.285811,45255.6%37.5%
68.75%161.991413,59085.7%55.6%
68.75%161.575614,38142.9%88.9%
53.33%151.264611,67857.1%50.0%
53.33%151.784512,67825.0%63.6%
57.14%141.685912,92983.3%37.5%
50.00%141.570211,83137.5%66.7%
46.15%131.472513,41260.0%37.5%
46.15%131.06638,37242.9%50.0%
46.15%132.976811,02833.3%57.1%
58.33%122.397313,70825.0%75.0%
63.64%111.087412,22385.7%25.0%
27.27%111.572712,3000.0%42.9%
27.27%112.369912,14020.0%33.3%
60.00%102.891813,68266.7%57.1%
20.00%102.485511,14833.3%14.3%
50.00%102.172411,27350.0%50.0%
30.00%101.166612,55240.0%20.0%
22.22%94.87539,09316.7%33.3%
25.00%81.996814,5190.0%28.6%
50.00%81.482012,71725.0%75.0%
42.86%71.271012,06433.3%50.0%
57.14%71.61,00916,388100.0%50.0%
57.14%72.11,00812,92350.0%66.7%
57.14%72.063413,43533.3%75.0%
50.00%61.890015,7930.0%60.0%
66.67%65.863911,39266.7%66.7%
16.67%61.965511,6320.0%50.0%
40.00%54.51,16414,7510.0%50.0%
40.00%50.990111,70933.3%50.0%
20.00%51.479311,7960.0%25.0%
80.00%56.189512,2450.0%100.0%
40.00%55.68699,1480.0%66.7%

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Lillia vs Karthus - Frequently Asked Questions

How does Lillia do against Karthus in League of Legends?

Karthus wins the Lillia vs Karthus matchup with a 72.7% win rate compared to Lillia's 27.3%, a 45.5 percentage point difference. This data is based on 11 recent ranked games in patch 26.11.

How does Lillia do against Karthus in the early game?

In the early game, Karthus has the advantage against Lillia with a 100.0% win rate versus 0.0%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lillia do against Karthus in the late game?

In the late game, Karthus takes over the Lillia vs Karthus matchup with a 57.1% win rate compared to 42.9%. Karthus scales better into team fights and objective contests after 25 minutes.

Who wins the Lillia vs Karthus matchup?

Karthus wins the matchup against Lillia with a 72.7% win rate in League of Legends patch 26.11. The 45.5 percentage point advantage means Karthus is significantly favored in this lane matchup based on 11 games analyzed.

What is the best Lillia build against Karthus?

The best Lillia build against Karthus includes Liandry's Torment, Riftmaker, Zhonya's Hourglass with Sorcerer's Shoes. This build achieves a 25.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Lillia runes against Karthus?

The best Lillia runes against Karthus use the Precision primary tree with Inspiration secondary. This rune setup achieves a 50.0% win rate in the Lillia vs Karthus matchup. See the full rune breakdown in the matchup comparison above.

Does Lillia counter Karthus?

No, Lillia struggles against Karthus with only a 27.3% win rate. Karthus has the advantage in this matchup. Lillia players should focus on safe farming and avoiding extended trades to minimize Karthus's lead.

How do I play Lillia against Karthus?

When playing Lillia against Karthus, play cautiously and avoid Karthus's power spikes. Look for jungle assistance and team-dependent plays since Karthus has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.