Lissandra - League of Legends Champion
Win Rate
51.3%
Pick Rate
2.2%

Lissandravs Neeko

AMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 20, 2026
MethodologyData Methodology

Lissandra vs Neeko is a decisive matchup in LoL patch 26.7. Lissandra wins with a 55.6% win rate (+11.1%) over Neeko based on 9 games. Lissandra holds the advantage in both the early and late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Neeko matchup.

Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Neeko - 55.6% win rateNeeko(55.6%)
Lissandra - 55.6% win rate in this matchup
Lissandra
55.6% WR
VS
Neeko vs Lissandra matchup - 44.4% win rate
Neeko
44.4% WR

Who Wins the Lissandra vs Neeko Matchup?

Lissandra wins the Lissandra vs Neeko matchup
Winner
Lissandra
Matches: 9
55.6%
Win Rate
44.4%
6.2
CS / min
5.5
951
DMG / min
1,040
14,281
Gold / game
14,114
184
Heal / min
87
583
DMG Mitigated / min
503
2.1
CC / min
1.7
50.0%
Early Game WR
50.0%
57.1%
Late Game WR
42.9%

Lissandra vs Neeko Matchup Summary

The Lissandra vs Neeko matchup is a decisive matchup in League of Legends ranked play. Based on 9 recent matches analyzed, Lissandra wins with a 55.6% win rate compared to Neeko's 44.4%, giving Lissandra a 11.1 percentage point advantage. Lissandra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Neeko players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Lissandra leads by 178 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra players can confidently pick into Neeko and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Neeko away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Neeko Laning Phase Breakdown

Lissandra wins the laning phase against Neeko in League of Legends

Lissandra is favored during the laning phase against Neeko, winning 4 out of 5 key stat categories. Lissandra holds advantages in farming, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.2Lissandra
5.5Neeko
Lissandra edges out Neeko by 0.8 CS per minute — a moderate farming advantage that adds up to roughly 12 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Lissandra.
Damage
951Lissandra
1,040Neeko
Neeko heavily out-damages Lissandra by 89 DMG/min, dominating both short trades and all-in fights. Lissandra should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Neeko's sustained damage advantage take over.
Economy
14,281Lissandra
14,114Neeko
Lissandra and Neeko generate nearly equal gold per game, with just a 167 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
2.1Lissandra
1.7Neeko
Lissandra provides 0.4 seconds more crowd control per minute than Neeko, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Lissandra coordinate with their jungler and control the pace of skirmishes.
Sustain
768Lissandra
590Neeko
Lissandra vastly out-sustains Neeko, healing and mitigating 178 more damage per minute. This massive durability gap means Lissandra can absorb significant punishment and remain in lane while Neeko is forced to recall. Building grievous wounds early is essential for Neeko, and focusing on burst trade patterns rather than sustained fights is critical.

Best Lissandra Build Against Neeko

Spellslinger's Shoes is the optimal boots choice against Neeko, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Neeko are Shadowflame, Zhonya's Hourglass and Malignance. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 66.7% win rate across 3 games — well above average and making it the top item path against Neeko. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Neeko matchup.

Early Game vs Late Game

Early Game
Lissandra
50.0%
+0.0% advantage
Lissandra early game win rateLissandra50.0%
Neeko early game win rateNeeko50.0%
Late Game
Lissandra
57.1%
+14.3% advantage
Lissandra late game win rateLissandra57.1%
Neeko late game win rateNeeko42.9%

The early game (first 15 minutes) is a toss-up between Lissandra and Neeko, with Lissandra holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Lissandra is far superior in the late game (25+ minutes), boasting a 57.1% win rate — 14.3 points above Neeko. Extended games heavily favor Lissandra, whose kit and scaling make them a dominant force in team fights and objective control.

Lissandra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Neeko players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Lissandra Runes Against Neeko

Sorcery rune tree - Lissandra primary runes vs NeekoSorcery
Arcane Comet - best Lissandra rune vs NeekoManaflow Band - best Lissandra rune vs NeekoTranscendence - best Lissandra rune vs NeekoScorch - best Lissandra rune vs Neeko
Resolve rune tree - Lissandra secondary runes vs NeekoResolve
Font of Life - best Lissandra rune vs NeekoBone Plating - best Lissandra rune vs Neeko
100.0% WR

Running Sorcery primary with Resolve secondary allows Lissandra to press their advantage against Neeko, amplifying the strengths that make this a favorable matchup.


Lissandra matchup data for League of Legends patch 26.7. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
60.00%1306.883712,37853.6%64.9%
57.52%1136.882011,83565.2%52.2%
50.00%766.890711,85747.2%52.5%
45.95%746.778211,93537.5%52.4%
47.95%736.982512,39648.3%47.7%
52.11%717.081212,61135.7%62.8%
53.62%696.788911,32658.1%50.0%
54.55%666.798912,99555.2%54.0%
50.00%626.990112,04736.7%62.5%
54.10%616.687711,06545.5%64.3%
57.38%616.276711,40053.6%60.6%
34.48%586.766810,83031.4%39.1%
40.00%556.372811,33333.3%45.2%
46.94%496.975711,65340.0%51.7%
50.00%486.776511,97850.0%50.0%
50.00%406.476411,31941.2%56.5%
65.00%407.283311,56863.6%66.7%
56.41%397.084511,79244.4%66.7%
60.00%356.876110,99150.0%70.6%
48.57%356.881511,55440.0%55.0%
36.36%336.784111,39846.7%27.8%
21.21%336.478711,43923.1%20.0%
63.33%307.380811,58476.5%46.1%
62.07%297.188313,06883.3%47.1%
58.62%296.596211,72763.6%55.6%
53.57%286.983410,91262.5%41.7%
46.43%286.68679,78147.1%45.5%
53.57%286.881411,53950.0%56.3%
59.26%277.079712,15157.1%61.5%
69.23%266.586913,22971.4%68.4%
57.69%266.679612,06775.0%42.9%
40.00%257.276711,82854.5%28.6%
64.00%256.680511,12450.0%73.3%
41.67%246.992712,63340.0%42.9%
66.67%247.178811,24454.5%76.9%
73.68%197.196712,77550.0%90.9%
44.44%187.31,06512,47460.0%25.0%
64.71%177.290311,48980.0%42.9%
33.33%156.473710,70622.2%50.0%
57.14%146.289412,26342.9%71.4%
42.86%147.375110,43150.0%25.0%
76.92%136.783113,11175.0%77.8%
38.46%136.082212,47860.0%25.0%
30.77%136.896711,40720.0%37.5%
15.38%136.584811,09216.7%14.3%
45.45%116.480812,11440.0%50.0%
27.27%116.792811,21620.0%33.3%
54.55%116.888611,95450.0%57.1%
40.00%106.882512,83166.7%28.6%
50.00%106.452910,44128.6%100.0%
55.56%96.295114,28150.0%57.1%
88.89%97.280612,70675.0%100.0%
55.56%97.288211,46775.0%40.0%
55.56%95.672312,03950.0%60.0%
55.56%97.786112,78766.7%50.0%
75.00%87.487510,71080.0%66.7%
57.14%77.387510,78575.0%33.3%
42.86%75.873510,32566.7%25.0%
85.71%77.087111,26283.3%100.0%
71.43%76.173511,33280.0%50.0%
50.00%61.761410,6240.0%60.0%
83.33%67.91,14313,99850.0%100.0%
33.33%67.796512,2420.0%66.7%
33.33%66.686711,32825.0%50.0%
50.00%62.45439,94466.7%33.3%
83.33%67.183312,020100.0%80.0%
16.67%67.26078,27816.7%0.0%
60.00%56.01,16411,19766.7%50.0%
40.00%53.07276,78640.0%0.0%
20.00%57.793410,62525.0%0.0%
20.00%55.05978,21425.0%0.0%
40.00%53.45178,76125.0%100.0%
80.00%55.064712,91850.0%100.0%
40.00%56.783411,7270.0%66.7%
60.00%56.077611,837100.0%33.3%
40.00%56.374111,1560.0%50.0%
60.00%56.897912,10050.0%66.7%
80.00%56.51,08510,600100.0%66.7%

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Lissandra vs Neeko - Frequently Asked Questions

How does Lissandra do against Neeko in League of Legends?

Lissandra wins the Lissandra vs Neeko matchup with a 55.6% win rate compared to Neeko's 44.4%, a 11.1 percentage point difference. This data is based on 9 recent ranked games in patch 26.7.

How does Lissandra do against Neeko in the early game?

In the early game, Lissandra has the advantage against Neeko with a 50.0% win rate versus 50.0%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Neeko in the late game?

In the late game, Lissandra takes over the Lissandra vs Neeko matchup with a 57.1% win rate compared to 42.9%. Lissandra scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Neeko matchup?

Lissandra wins the matchup against Neeko with a 55.6% win rate in League of Legends patch 26.7. The 11.1 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 9 games analyzed.

What is the best Lissandra build against Neeko?

The best Lissandra build against Neeko includes Shadowflame, Zhonya's Hourglass, Malignance with Spellslinger's Shoes. This build achieves a 66.7% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Neeko?

The best Lissandra runes against Neeko use the Sorcery primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Lissandra vs Neeko matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Neeko?

Yes, Lissandra has a favorable matchup against Neeko with a 55.6% win rate. Lissandra strongly counters Neeko in lane based on current patch 26.7 data.

How do I play Lissandra against Neeko?

When playing Lissandra against Neeko, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.