Lissandra - League of Legends Champion
Win Rate
51.6%
Pick Rate
1.7%

Lissandravs Neeko

SMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 10, 2026
MethodologyData Methodology

Lissandra vs Neeko is a decisive matchup in LoL patch 26.11. Lissandra wins with a 55.6% win rate (+11.1%) over Neeko based on 9 games. Lissandra holds the advantage in both the early and late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Neeko matchup.

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Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lissandra - 55.6% win rate in this matchup
Lissandra
55.6% WR
VS
Neeko vs Lissandra matchup - 44.4% win rate
Neeko
44.4% WR

Who Wins the Lissandra vs Neeko Matchup?

Lissandra wins the Lissandra vs Neeko matchup
Winner
Lissandra
Matches: 9
55.6%
Win Rate
44.4%
6.2
CS / min
5.7
814
DMG / min
772
11,096
Gold / game
10,607
141
Heal / min
89
384
DMG Mitigated / min
376
1.6
CC / min
1.5
50.0%
Early Game WR
50.0%
66.7%
Late Game WR
33.3%

Lissandra vs Neeko Matchup Summary

The Lissandra vs Neeko matchup is a decisive matchup in League of Legends ranked play. Based on 9 recent matches analyzed, Lissandra wins with a 55.6% win rate compared to Neeko's 44.4%, giving Lissandra a 11.1 percentage point advantage. Lissandra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Neeko players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Lissandra leads by 60 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra players can confidently pick into Neeko and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Neeko away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Neeko Laning Phase Breakdown

Lissandra wins the laning phase against Neeko in League of Legends

Lissandra is favored during the laning phase against Neeko, winning 5 out of 5 key stat categories. Lissandra holds advantages in farming, damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.2Lissandra
5.7Neeko
Lissandra edges out Neeko by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 7 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Lissandra.
Damage
814Lissandra
772Neeko
Lissandra deals 42 more champion damage per minute than Neeko. While noticeable in extended trades, this gap can be offset by Neeko choosing favorable fight windows, such as engaging when Lissandra's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
11,096Lissandra
10,607Neeko
Lissandra earns 488 more gold per game than Neeko, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Lissandra slightly faster item completions.
Utility
1.6Lissandra
1.5Neeko
Both Lissandra and Neeko provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
525Lissandra
465Neeko
Lissandra heals and mitigates 60 more damage per minute than Neeko, providing moderate extra durability. This sustain edge allows Lissandra to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Neeko.

Best Lissandra Build Against Neeko

Mercury's Treads is the optimal boots choice against Neeko, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Neeko are Imperial Mandate, Malignance and Zeke's Convergence. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Neeko. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Neeko matchup.

Early Game vs Late Game

Early Game
Lissandra
50.0%
+0.0% advantage
Lissandra early game win rateLissandra50.0%
Neeko early game win rateNeeko50.0%
Late Game
Lissandra
66.7%
+33.3% advantage
Lissandra late game win rateLissandra66.7%
Neeko late game win rateNeeko33.3%

The early game (first 15 minutes) is a toss-up between Lissandra and Neeko, with Lissandra holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Lissandra is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Neeko. Extended games heavily favor Lissandra, whose kit and scaling make them a dominant force in team fights and objective control.

Lissandra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Neeko players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Lissandra Runes Against Neeko

Domination rune tree - Lissandra primary runes vs NeekoDomination
Electrocute - best Lissandra rune vs NeekoCheap Shot - best Lissandra rune vs NeekoGrisly Mementos - best Lissandra rune vs NeekoUltimate Hunter - best Lissandra rune vs Neeko
Inspiration rune tree - Lissandra secondary runes vs NeekoInspiration
Biscuit Delivery - best Lissandra rune vs NeekoCosmic Insight - best Lissandra rune vs Neeko
100.0% WR

Running Domination primary with Inspiration secondary allows Lissandra to press their advantage against Neeko, amplifying the strengths that make this a favorable matchup.


Lissandra matchup data for League of Legends patch 26.11. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
58.02%1316.885811,86355.0%60.6%
61.60%1256.791812,36268.6%56.8%
54.47%1236.988112,08353.1%55.4%
54.95%1116.874811,41055.8%54.2%
51.52%996.684011,78453.5%50.0%
50.00%986.985712,17845.0%53.5%
55.56%816.992811,72160.5%51.2%
44.74%766.878111,74844.1%45.2%
57.53%736.785911,06161.5%52.9%
52.86%706.487411,10854.3%51.4%
48.53%687.090811,10755.0%39.3%
53.73%676.178010,94653.1%54.3%
48.28%586.778112,35453.9%43.8%
41.07%566.774210,62436.7%46.1%
58.93%566.573210,32060.6%56.5%
53.70%546.488811,71551.9%55.6%
52.08%486.888112,08468.2%38.5%
55.32%476.384311,46055.6%55.2%
51.16%436.883412,58750.0%51.9%
43.59%396.482510,76435.0%52.6%
46.15%396.577310,88341.2%50.0%
39.47%386.680212,13937.5%40.9%
56.76%376.374210,61842.1%72.2%
56.76%376.878712,41658.8%55.0%
56.76%376.880811,53576.9%45.8%
32.43%377.080410,61129.4%35.0%
48.65%377.083812,68066.7%40.0%
33.33%336.992311,15131.3%35.3%
66.67%306.784412,08075.0%61.1%
65.52%296.986511,46770.6%58.3%
53.57%286.785811,89133.3%63.2%
61.54%267.193811,18175.0%40.0%
37.50%246.470111,94744.4%33.3%
58.33%247.382212,59060.0%57.1%
50.00%227.076411,84454.5%45.5%
54.55%226.61,01413,02066.7%50.0%
31.82%226.768410,84522.2%38.5%
33.33%216.874611,90044.4%25.0%
57.14%215.782310,46554.5%60.0%
73.68%196.980510,70775.0%72.7%
57.89%196.985412,58375.0%45.5%
61.11%187.488713,06550.0%70.0%
38.89%187.294812,87866.7%25.0%
58.82%176.51,06612,41342.9%70.0%
62.50%166.268611,07572.7%40.0%
56.25%166.892312,01450.0%57.1%
66.67%156.984213,080100.0%54.5%
64.29%146.190813,43275.0%60.0%
50.00%144.254910,94350.0%50.0%
64.29%146.779211,67883.3%50.0%
57.14%147.01,08911,13070.0%25.0%
53.85%136.693411,37550.0%57.1%
58.33%127.51,05412,44966.7%50.0%
63.64%116.090612,08133.3%100.0%
45.45%115.590412,09425.0%57.1%
63.64%112.682511,48750.0%71.4%
30.00%105.47418,70242.9%0.0%
70.00%107.194411,75183.3%50.0%
70.00%106.21,13613,233100.0%50.0%
50.00%106.889914,6330.0%62.5%
70.00%106.481112,0790.0%87.5%
55.56%96.281411,09650.0%66.7%
33.33%96.885511,75450.0%20.0%
66.67%96.578212,16033.3%83.3%
22.22%92.55189,7830.0%40.0%
85.71%77.71,15311,498100.0%66.7%
71.43%76.482813,449100.0%66.7%
57.14%77.384211,22350.0%66.7%
100.00%78.28329,161100.0%100.0%
57.14%72.986810,35560.0%50.0%
42.86%77.48559,99550.0%33.3%
57.14%77.080513,44150.0%66.7%
50.00%66.469210,47333.3%66.7%
33.33%66.78659,25050.0%0.0%
50.00%65.784212,7490.0%50.0%
80.00%56.88199,894100.0%66.7%
60.00%57.671711,88250.0%66.7%
60.00%57.593814,8270.0%75.0%
40.00%52.155411,1230.0%40.0%
60.00%56.576611,909100.0%50.0%
40.00%56.95498,21433.3%50.0%
80.00%53.669512,683100.0%50.0%
60.00%52.24318,35366.7%50.0%
60.00%57.51,17014,036100.0%33.3%
40.00%55.596514,4230.0%40.0%
80.00%57.31,24116,644100.0%75.0%
80.00%56.388712,12650.0%100.0%
60.00%56.074710,44750.0%100.0%
20.00%56.67479,3500.0%33.3%

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Lissandra vs Neeko - Frequently Asked Questions

How does Lissandra do against Neeko in League of Legends?

Lissandra wins the Lissandra vs Neeko matchup with a 55.6% win rate compared to Neeko's 44.4%, a 11.1 percentage point difference. This data is based on 9 recent ranked games in patch 26.11.

How does Lissandra do against Neeko in the early game?

In the early game, Lissandra has the advantage against Neeko with a 50.0% win rate versus 50.0%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Neeko in the late game?

In the late game, Lissandra takes over the Lissandra vs Neeko matchup with a 66.7% win rate compared to 33.3%. Lissandra scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Neeko matchup?

Lissandra wins the matchup against Neeko with a 55.6% win rate in League of Legends patch 26.11. The 11.1 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 9 games analyzed.

What is the best Lissandra build against Neeko?

The best Lissandra build against Neeko includes Imperial Mandate, Malignance, Zeke's Convergence with Mercury's Treads. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Neeko?

The best Lissandra runes against Neeko use the Domination primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Lissandra vs Neeko matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Neeko?

Yes, Lissandra has a favorable matchup against Neeko with a 55.6% win rate. Lissandra strongly counters Neeko in lane based on current patch 26.11 data.

How do I play Lissandra against Neeko?

When playing Lissandra against Neeko, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.