Lissandra - League of Legends Champion
Win Rate
48.5%
Pick Rate
2.0%

Lissandravs Syndra

FMage
Patch26.13
Matches9,048,502
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 15, 2026
MethodologyData Methodology

Lissandra vs Syndra is a decisive matchup in LoL patch 26.13. Syndra wins with a 56.3% win rate (+12.5%) over Lissandra based on 16 games. Syndra wins the early laning phase while Lissandra scales better into the late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Syndra matchup.

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Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lissandra - 43.8% win rate in this matchup
Lissandra
43.8% WR
VS
Syndra vs Lissandra matchup - 56.3% win rate
Syndra
56.3% WR

Who Wins the Lissandra vs Syndra Matchup?

Syndra wins the Lissandra vs Syndra matchup
Winner
Syndra
Matches: 16
43.8%
Win Rate
56.3%
6.3
CS / min
6.9
661
DMG / min
1,004
11,043
Gold / game
13,509
135
Heal / min
70
403
DMG Mitigated / min
330
1.3
CC / min
1.4
37.5%
Early Game WR
62.5%
50.0%
Late Game WR
50.0%

Lissandra vs Syndra Matchup Summary

The Lissandra vs Syndra matchup is a decisive matchup in League of Legends ranked play. Based on 16 recent matches analyzed, Syndra wins with a 56.3% win rate compared to Lissandra's 43.8%, giving Syndra a 12.5 percentage point advantage. Game phase dynamics play a critical role here: Syndra controls the early laning stage, but Lissandra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Syndra needs to press advantages before Lissandra reaches their power spikes, while Lissandra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in damage output, where Syndra leads by 343 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra has a strong advantage in this matchup. Lissandra players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Syndra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Syndra Laning Phase Breakdown

Syndra wins the laning phase against Lissandra in League of Legends

Syndra is favored during the laning phase against Lissandra, winning 4 out of 5 key stat categories. Syndra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
6.3Lissandra
6.9Syndra
Syndra edges out Lissandra by 0.5 CS per minute — a moderate farming advantage that adds up to roughly 8 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Syndra.
Damage
661Lissandra
1,004Syndra
Syndra heavily out-damages Lissandra by 343 DMG/min, dominating both short trades and all-in fights. Lissandra should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Syndra's sustained damage advantage take over.
Economy
11,043Lissandra
13,509Syndra
Syndra generates a commanding 2,466 more gold per game than Lissandra. This substantial economic advantage means Syndra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Lissandra should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.3Lissandra
1.4Syndra
Both Lissandra and Syndra provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
539Lissandra
400Syndra
Lissandra heals and mitigates 139 more damage per minute than Syndra, providing moderate extra durability. This sustain edge allows Lissandra to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Syndra.

Best Lissandra Build Against Syndra

Chainlaced Crushers is the optimal boots choice against Syndra, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Syndra are Shadowflame, Zhonya's Hourglass and Malignance. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Syndra matchup.

Early Game vs Late Game

Early Game
Syndra
62.5%
+25.0% advantage
Lissandra early game win rateLissandra37.5%
Syndra early game win rateSyndra62.5%
Late Game
Lissandra
50.0%
+0.0% advantage
Lissandra late game win rateLissandra50.0%
Syndra late game win rateSyndra50.0%

Syndra dominates the early game (first 15 minutes) with a commanding 62.5% win rate — a 25.0 percentage point lead over Lissandra. This lopsided early game means Syndra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Lissandra at 50.0% win rate — only 0.0 points ahead of Syndra. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

The power dynamics shift as the game progresses — Syndra has the edge early, but Lissandra gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Lissandra Runes Against Syndra

Domination rune tree - Lissandra primary runes vs SyndraDomination
Electrocute - best Lissandra rune vs SyndraCheap Shot - best Lissandra rune vs SyndraGrisly Mementos - best Lissandra rune vs SyndraUltimate Hunter - best Lissandra rune vs Syndra
Sorcery rune tree - Lissandra secondary runes vs SyndraSorcery
Manaflow Band - best Lissandra rune vs SyndraScorch - best Lissandra rune vs Syndra
100.0% WR

The Domination and Sorcery rune setup gives Lissandra the best tools to compete against Syndra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Lissandra matchup data for League of Legends patch 26.13. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.13
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
62.50%1046.287011,65362.8%62.3%
52.27%446.691712,49561.1%46.1%
58.14%437.082910,86958.6%57.1%
65.79%386.789712,41276.9%60.0%
43.33%306.975712,69758.3%33.3%
41.38%296.767811,09846.1%37.5%
37.04%276.594612,36850.0%26.7%
60.00%256.486410,78360.0%60.0%
59.09%226.282611,82060.0%58.3%
72.73%226.791113,21566.7%76.9%
60.00%206.892911,05960.0%60.0%
36.84%195.66708,44541.7%28.6%
58.82%176.372011,82066.7%54.5%
43.75%166.366111,04337.5%50.0%
68.75%165.875610,74862.5%75.0%
37.50%166.989311,18642.9%33.3%
43.75%165.875610,75314.3%66.7%
33.33%156.466010,85128.6%37.5%
66.67%157.186211,10287.5%42.9%
53.33%157.089611,55537.5%71.4%
61.54%135.478012,570100.0%50.0%
66.67%126.091911,53550.0%83.3%
33.33%126.370010,67528.6%40.0%
40.00%107.087111,36840.0%40.0%
60.00%105.775212,2450.0%66.7%
60.00%106.987410,44650.0%75.0%
0.00%106.584210,4170.0%0.0%
55.56%96.681910,51740.0%75.0%
77.78%96.192011,05260.0%100.0%
37.50%87.385812,88350.0%33.3%
37.50%85.164810,4930.0%75.0%
42.86%74.863811,84733.3%50.0%
85.71%76.191115,773100.0%83.3%
42.86%75.889612,99050.0%40.0%
42.86%77.493311,80066.7%25.0%
42.86%77.297313,29450.0%40.0%
33.33%62.36469,85933.3%33.3%
16.67%67.459211,22733.3%0.0%
20.00%52.66667,50025.0%0.0%
20.00%54.893311,8550.0%33.3%
60.00%57.181411,48166.7%50.0%
40.00%57.081211,2710.0%100.0%
60.00%57.372411,814100.0%33.3%
80.00%57.178312,25466.7%100.0%
20.00%57.01,07212,6230.0%33.3%
60.00%55.971211,78866.7%50.0%
20.00%57.086212,46533.3%0.0%

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Lissandra vs Syndra - Frequently Asked Questions

How does Lissandra do against Syndra in League of Legends?

Syndra wins the Lissandra vs Syndra matchup with a 56.3% win rate compared to Lissandra's 43.8%, a 12.5 percentage point difference. This data is based on 16 recent ranked games in patch 26.13.

How does Lissandra do against Syndra in the early game?

In the early game, Syndra has the advantage against Lissandra with a 62.5% win rate versus 37.5%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Syndra in the late game?

In the late game, Lissandra takes over the Lissandra vs Syndra matchup with a 50.0% win rate compared to 50.0%. Lissandra scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Syndra matchup?

Syndra wins the matchup against Lissandra with a 56.3% win rate in League of Legends patch 26.13. The 12.5 percentage point advantage means Syndra is significantly favored in this lane matchup based on 16 games analyzed.

What is the best Lissandra build against Syndra?

The best Lissandra build against Syndra includes Shadowflame, Zhonya's Hourglass, Malignance with Chainlaced Crushers. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Syndra?

The best Lissandra runes against Syndra use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Lissandra vs Syndra matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Syndra?

No, Lissandra struggles against Syndra with only a 43.8% win rate. Syndra has the advantage in this matchup. Lissandra players should focus on safe farming and avoiding extended trades to minimize Syndra's lead.

How do I play Lissandra against Syndra?

When playing Lissandra against Syndra, play cautiously and avoid Syndra's power spikes. Focus on safe farming — you outscale Syndra in the late game. Use the matchup-specific build and runes above to optimize your chances.