Lissandra, League of Legends champion
Win Rate
50.5%
Pick Rate
2.0%
Ban Rate
2.2%

Lissandra vs Syndra

Lissandra C TierMage
Patch
26.20
Games
2,656
Lane
All Lanes
Tier
All Tiers
Last Updated
Oct 13, 2026 UTC
Methodology
Data Methodology

Lissandra vs Syndra is a decisive matchup in LoL patch 26.20. Lissandra wins with a 56.0% win rate (+12.0%) over Syndra based on 50 games. Syndra wins the early laning phase while Lissandra scales better into the late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Syndra matchup.

Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lissandra
Lissandra
56.3%
VS
Syndra
43.8%
Syndra

Who wins Lissandra vs Syndra?

Slight Lissandra edgeLow confidence

Lissandra wins 56.3% of these games. With this many games the true rate is most likely between 42.3% and 69.3% (95% range).

Expected
51.0%
From both champions' overall Mid win rates
Matchup effect
+5.2 pts
Observed minus expected
Sample
48 games
Lane: Mid
vs patch 26.19
—
Not enough games on both patches

Lane: Mid · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.20 · Oct 10 – Oct 11

Key takeaways

  • Current data slightly favors Lissandra, but the sample is too limited for a strong conclusion: Lissandra wins 56.3% of 48 games (95% range 42.3–69.3%).
  • Both champions' overall Mid win rates predict 51.0% for Lissandra; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
  • Neither side reliably wins the lane: the average gold difference at 15 minutes is 126, within the margin of error (48 games).
  • Lissandra players pick Arcane Comet far more often against Syndra: 36.7% of their other Mid games, 58.3% here.
How we calculate this

Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.

A game only counts when Lissandra and Syndra played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.

The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.

Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.

"What changes" compares Lissandra's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).

Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.

Lissandra vs Syndra Laning Stats

LissandraSyndra

At 15 minutes

Gold difference
−126
Within the margin of error
95% range −486 to +233
XP difference
−21
Within the margin of error
95% range −331 to +289
CS difference
−4.0
Within the margin of error
95% range −8.7 to +0.8
2.02
Kills before 15 min
2.06
1.98
Deaths before 15 min
2.40
0.71
Solo kills before 15 min
0.73
4.2%
First blood
4.2%

Whole-game averages

6.6
CS / min
6.7
868
DMG / min
979
12,940
Gold / game
13,431
171
Heal / min
76
393
DMG Mitigated / min
322
1.5
CC / min
1.3

Lissandra vs Syndra Win Rate by Game Length

Lissandra's win rate against Syndra by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.

Too few games
Under 20 min
2 games
Too few games
20–25 min
4 games
Too few games
25–30 min
13 games
Too few games
30–35 min
16 games
Too few games
35+ min
13 games
Lissandra vs Syndra95% rangeLissandra usual (Mid)

No game length stands out: Lissandra's results against Syndra in short and long games are within the margin of error of each other.

Lissandra vs Syndra Power Spikes

Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.

  1. Lane (15 min)EvenLissandra gold at 15: −126
  2. First itemLissandraLissandra: 10.4 min · Syndra: 10.9 min
  3. Games under 20 minInsufficient data
  4. 20–30 min gamesInsufficient data
  5. 30+ min gamesInsufficient data

What Lissandra Changes Against Syndra

Choices Lissandra players make noticeably more or less often in this matchup than in their other Mid games.

  • Arcane Comet
    Arcane CometKeystone
    Usually
    36.7%
    vs Syndra
    58.3%
    +21.6 pts50.0% WR here
  • Domination
    DominationSecondary tree
    Usually
    33.8%
    vs Syndra
    54.2%
    +20.4 pts50.0% WR here
  • Scorch
    ScorchRune
    Usually
    41.8%
    vs Syndra
    58.3%
    +16.6 pts53.6% WR here
  • Grisly Mementos
    Usually
    53.5%
    vs Syndra
    37.5%
    −16.0 pts
  • Electrocute
    ElectrocuteKeystone
    Usually
    57.3%
    vs Syndra
    41.7%
    −15.7 pts65.0% WR here
  • Doran's RingHealth PotionHealth PotionStealth WardOracle Lens
    Doran's Ring + Health Potion + Health Potion + Stealth Ward + Oracle LensStarting items
    Usually
    0.7%
    vs Syndra
    4.2%
    +3.5 pts

Best Lissandra Build vs Syndra

Usual Lissandra build (Mid)

83.3% win rate · 12 games

Against Syndra

Not enough matchup-specific build data: only 10 of 30 Lissandra games against Syndra carried a complete build, which is too few to recommend an item path from. Use Lissandra's standard build instead.

  • Lissandra usually completes Malignance first, at 10.4 min (median of 31 games).
  • Syndra usually completes Luden's Echo first, at 10.9 min (median of 34 games).
  • Skill priority: Q > W > E — the same as usual.

Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.

Best Lissandra Runes vs Syndra

Usual Lissandra runes (Mid)

Arcane CometArcane Comet
Sorcery
Manaflow BandTranscendenceScorch
Resolve
Bone PlatingOvergrowth
Attack Speed (offense)Adaptive Force (flex)Health (defense)

86.7% win rate · 15 games

Against Syndra

Arcane CometArcane Comet
Sorcery
Manaflow BandTranscendenceScorch
Domination
Cheap ShotUltimate Hunter
Adaptive Force (offense)Adaptive Force (flex)Health Scaling (defense)

52.4% win rate · 21 games

MetaBot Desktop

Plan your Lissandra draft in Draft Lab

Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.

  • Full 5v5 draft board
  • Lane matchup win rates
  • Pick and ban suggestions
Draft Lab in MetaBot Desktop

Lissandra matchup data for League of Legends patch 26.20. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Other Lissandra Matchups

Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.

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Lissandra vs Syndra FAQ - Patch 26.20

Who wins Lissandra vs Syndra?

Current data slightly favors Lissandra, but the sample is too limited for a strong conclusion: Lissandra wins 56.3% of 48 games (95% range 42.3–69.3%).

What is Lissandra's win rate against Syndra?

Lissandra wins 56.3% of 48 Mid games against Syndra on patch 26.20 (95% range 42.3–69.3%). Based on both champions' overall Mid win rates, 51.0% would be expected.

Does Lissandra counter Syndra?

Not clearly. Lissandra wins 56.3% of 48 games against Syndra, and the 95% range (42.3–69.3%) includes 50%, so neither champion reliably counters the other on current data.

Who wins lane, Lissandra or Syndra?

Neither side reliably wins the lane: the average gold difference at 15 minutes is 126, within the margin of error (48 games).

Does Lissandra outscale Syndra?

There are too few games of each length to tell yet.

When is Syndra strongest against Lissandra?

On current data there is no stage of the game where Syndra is ahead of Lissandra beyond the margin of error.

What should Lissandra build against Syndra?

There are not enough games for a matchup-specific core, so use Lissandra's usual Mid core: Shadowflame, Zhonya's Hourglass, Hextech Rocketbelt. The biggest change against Syndra: Doran's Ring + Health Potion + Health Potion + Stealth Ward + Oracle Lens (0.7% usually, 4.2% here).

What runes should Lissandra use against Syndra?

Arcane Comet with Sorcery and Domination — 52.4% over 21 games against Syndra. The biggest change against Syndra: Arcane Comet (36.7% usually, 58.3% here).