
Lissandra vs Syndra is a decisive matchup in LoL patch 26.17. Lissandra wins with a 58.7% win rate (+17.4%) over Syndra based on 46 games. Syndra wins the early laning phase while Lissandra scales better into the late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Syndra matchup.
Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

The Lissandra vs Syndra matchup is a decisive matchup in League of Legends ranked play. Based on 46 recent matches analyzed, Lissandra wins with a 58.7% win rate compared to Syndra's 41.3%, giving Lissandra a 17.4 percentage point advantage. Game phase dynamics play a critical role here: Syndra controls the early laning stage, but Lissandra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Syndra needs to press advantages before Lissandra reaches their power spikes, while Lissandra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Lissandra leads by 173 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra players can confidently pick into Syndra and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Syndra away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Syndra is favored during the laning phase against Lissandra, winning 3 out of 5 key stat categories. Syndra holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Spellslinger's Shoes is the optimal boots choice against Syndra, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Syndra are Shadowflame, Zhonya's Hourglass and Malignance. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 62.5% win rate across 8 games — well above average and making it the top item path against Syndra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Syndra matchup.
Syndra dominates the early game (first 15 minutes) with a commanding 57.1% win rate — a 14.3 percentage point lead over Lissandra. This lopsided early game means Syndra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Lissandra is far superior in the late game (25+ minutes), boasting a 65.6% win rate — 31.2 points above Syndra. Extended games heavily favor Lissandra, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Syndra must aggressively press their early advantage and close out the game before Lissandra reaches their scaling breakpoints. If Lissandra survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Running Domination primary with Sorcery secondary allows Lissandra to press their advantage against Syndra, amplifying the strengths that make this a favorable matchup.
Lissandra matchup data for League of Legends patch 26.17. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 55.88% | 102 | 7.0 | 798 | 11,971 | 65.1% | 49.1% | |
| 56.96% | 79 | 6.5 | 751 | 11,101 | 61.8% | 53.3% | |
| 49.32% | 73 | 6.5 | 819 | 10,748 | 51.1% | 46.4% | |
| 45.71% | 70 | 6.9 | 872 | 11,662 | 51.6% | 41.0% | |
| 41.27% | 63 | 6.8 | 854 | 12,057 | 40.7% | 41.7% | |
| 55.00% | 60 | 6.9 | 789 | 11,049 | 60.0% | 50.0% | |
| 40.68% | 59 | 6.2 | 855 | 12,445 | 39.1% | 41.7% | |
| 42.86% | 56 | 6.9 | 739 | 12,172 | 44.0% | 41.9% | |
| 57.45% | 47 | 6.8 | 854 | 11,928 | 65.4% | 47.6% | |
| 58.70% | 46 | 6.6 | 790 | 12,519 | 42.9% | 65.6% | |
| 51.11% | 45 | 6.3 | 731 | 11,146 | 45.8% | 57.1% | |
| 61.90% | 42 | 6.9 | 852 | 11,328 | 61.9% | 61.9% | |
| 51.43% | 35 | 6.8 | 843 | 11,171 | 47.1% | 55.6% | |
| 56.25% | 32 | 6.4 | 888 | 12,382 | 53.9% | 57.9% | |
| 35.48% | 31 | 7.0 | 939 | 10,577 | 38.9% | 30.8% | |
| 46.67% | 30 | 5.8 | 674 | 11,082 | 30.8% | 58.8% | |
| 48.00% | 25 | 6.7 | 700 | 10,532 | 50.0% | 46.1% | |
| 40.00% | 25 | 7.2 | 977 | 12,869 | 53.9% | 25.0% | |
| 43.48% | 23 | 6.7 | 833 | 11,128 | 55.6% | 35.7% | |
| 40.91% | 22 | 5.7 | 767 | 11,268 | 11.1% | 61.5% | |
| 45.45% | 22 | 6.0 | 762 | 11,492 | 50.0% | 42.9% | |
| 40.91% | 22 | 6.8 | 627 | 10,026 | 28.6% | 62.5% | |
| 52.38% | 21 | 6.8 | 839 | 11,737 | 63.6% | 40.0% | |
| 57.89% | 19 | 6.8 | 907 | 11,403 | 50.0% | 71.4% | |
| 38.89% | 18 | 6.7 | 790 | 10,534 | 55.6% | 22.2% | |
| 55.56% | 18 | 6.2 | 749 | 11,881 | 60.0% | 53.9% | |
| 38.89% | 18 | 5.9 | 672 | 10,544 | 57.1% | 27.3% | |
| 58.82% | 17 | 6.7 | 924 | 11,796 | 57.1% | 60.0% | |
| 35.29% | 17 | 6.8 | 738 | 12,554 | 50.0% | 22.2% | |
| 37.50% | 16 | 6.5 | 846 | 13,110 | 33.3% | 38.5% | |
| 50.00% | 16 | 7.5 | 907 | 12,182 | 42.9% | 55.6% | |
| 46.67% | 15 | 7.0 | 741 | 11,896 | 42.9% | 50.0% | |
| 57.14% | 14 | 6.4 | 890 | 10,658 | 83.3% | 37.5% | |
| 50.00% | 14 | 7.3 | 965 | 11,590 | 28.6% | 71.4% | |
| 42.86% | 14 | 6.9 | 768 | 10,082 | 42.9% | 42.9% | |
| 15.38% | 13 | 6.7 | 783 | 10,753 | 14.3% | 16.7% | |
| 30.77% | 13 | 6.8 | 721 | 12,091 | 33.3% | 28.6% | |
| 58.33% | 12 | 6.8 | 921 | 12,104 | 50.0% | 66.7% | |
| 75.00% | 12 | 5.1 | 713 | 10,438 | 100.0% | 57.1% | |
| 66.67% | 12 | 6.8 | 915 | 11,417 | 66.7% | 66.7% | |
| 55.56% | 9 | 5.4 | 627 | 10,783 | 66.7% | 50.0% | |
| 44.44% | 9 | 6.2 | 886 | 13,608 | 66.7% | 33.3% | |
| 55.56% | 9 | 7.3 | 1,124 | 11,481 | 100.0% | 33.3% | |
| 50.00% | 8 | 2.6 | 538 | 9,215 | 50.0% | 50.0% | |
| 50.00% | 8 | 5.6 | 813 | 9,888 | 0.0% | 80.0% | |
| 50.00% | 8 | 7.2 | 1,152 | 14,851 | 100.0% | 33.3% | |
| 57.14% | 7 | 6.8 | 901 | 11,368 | 25.0% | 100.0% | |
| 71.43% | 7 | 7.2 | 812 | 11,583 | 66.7% | 75.0% | |
| 85.71% | 7 | 7.1 | 810 | 10,313 | 100.0% | 75.0% | |
| 0.00% | 6 | 6.8 | 823 | 14,254 | 0.0% | 0.0% | |
| 50.00% | 6 | 7.1 | 758 | 10,339 | 100.0% | 25.0% | |
| 100.00% | 6 | 2.6 | 476 | 8,460 | 100.0% | 100.0% | |
| 50.00% | 6 | 7.3 | 914 | 11,858 | 25.0% | 100.0% | |
| 80.00% | 5 | 7.0 | 885 | 11,410 | 100.0% | 50.0% | |
| 40.00% | 5 | 6.6 | 821 | 9,552 | 33.3% | 50.0% | |
| 60.00% | 5 | 6.6 | 809 | 10,846 | 50.0% | 66.7% | |
| 60.00% | 5 | 4.3 | 1,128 | 12,522 | 100.0% | 50.0% | |
| 80.00% | 5 | 6.9 | 791 | 11,366 | 66.7% | 100.0% | |
| 0.00% | 5 | 5.7 | 709 | 10,157 | 0.0% | 0.0% | |
| 60.00% | 5 | 5.8 | 1,050 | 11,540 | 50.0% | 66.7% | |
| 60.00% | 5 | 7.7 | 1,114 | 15,005 | 100.0% | 50.0% | |
| 60.00% | 5 | 6.7 | 765 | 12,180 | 66.7% | 50.0% | |
| 60.00% | 5 | 7.9 | 747 | 12,400 | 100.0% | 0.0% | |
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Lissandra wins the Lissandra vs Syndra matchup with a 58.7% win rate compared to Syndra's 41.3%, a 17.4 percentage point difference. This data is based on 46 recent ranked games in patch 26.17.
In the early game, Syndra has the advantage against Lissandra with a 57.1% win rate versus 42.9%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
In the late game, Lissandra takes over the Lissandra vs Syndra matchup with a 65.6% win rate compared to 34.4%. Lissandra scales better into team fights and objective contests after 25 minutes.
Lissandra wins the matchup against Syndra with a 58.7% win rate in League of Legends patch 26.17. The 17.4 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 46 games analyzed.
The best Lissandra build against Syndra includes Shadowflame, Zhonya's Hourglass, Malignance with Spellslinger's Shoes. This build achieves a 62.5% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
The best Lissandra runes against Syndra use the Domination primary tree with Sorcery secondary. This rune setup achieves a 65.0% win rate in the Lissandra vs Syndra matchup. See the full rune breakdown in the matchup comparison above.
Yes, Lissandra has a favorable matchup against Syndra with a 58.7% win rate. Lissandra strongly counters Syndra in lane based on current patch 26.17 data.
When playing Lissandra against Syndra, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Syndra. Build the recommended items and runes for this specific matchup for the best results.
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