Lissandra - League of Legends Champion
Win Rate
51.4%
Pick Rate
2.2%

Lissandravs Syndra

AMage
Patch26.7
Matches508,082
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 14, 2026
MethodologyData Methodology

Lissandra vs Syndra is a decisive matchup in LoL patch 26.7. Syndra wins with a 60.0% win rate (+20.0%) over Lissandra based on 25 games. Lissandra wins the early laning phase while Syndra scales better into the late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Syndra matchup.

Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Syndra - 40.0% win rateSyndra(40.0%)
Lissandra - 40.0% win rate in this matchup
Lissandra
40.0% WR
VS
Syndra vs Lissandra matchup - 60.0% win rate
Syndra
60.0% WR

Who Wins the Lissandra vs Syndra Matchup?

Syndra wins the Lissandra vs Syndra matchup
Winner
Syndra
Matches: 25
40.0%
Win Rate
60.0%
7.2
CS / min
7.1
767
DMG / min
877
11,828
Gold / game
12,746
140
Heal / min
78
423
DMG Mitigated / min
310
1.5
CC / min
1.4
54.5%
Early Game WR
45.5%
28.6%
Late Game WR
71.4%

Lissandra vs Syndra Matchup Summary

The Lissandra vs Syndra matchup is a decisive matchup in League of Legends ranked play. Based on 25 recent matches analyzed, Syndra wins with a 60.0% win rate compared to Lissandra's 40.0%, giving Syndra a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Lissandra controls the early laning stage, but Syndra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Lissandra needs to press advantages before Syndra reaches their power spikes, while Syndra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Lissandra leads by 174 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra has a strong advantage in this matchup. Lissandra players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Syndra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Syndra Laning Phase Breakdown

Lissandra wins the laning phase against Syndra in League of Legends

Lissandra is favored during the laning phase against Syndra, winning 3 out of 5 key stat categories. Lissandra holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.

Farming
7.2Lissandra
7.1Syndra
Lissandra and Syndra farm at nearly identical rates in this matchup, with only a 0.2 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
767Lissandra
877Syndra
Syndra heavily out-damages Lissandra by 110 DMG/min, dominating both short trades and all-in fights. Lissandra should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Syndra's sustained damage advantage take over.
Economy
11,828Lissandra
12,746Syndra
Syndra generates a commanding 919 more gold per game than Lissandra. This substantial economic advantage means Syndra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Lissandra should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.5Lissandra
1.4Syndra
Both Lissandra and Syndra provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
562Lissandra
388Syndra
Lissandra vastly out-sustains Syndra, healing and mitigating 174 more damage per minute. This massive durability gap means Lissandra can absorb significant punishment and remain in lane while Syndra is forced to recall. Building grievous wounds early is essential for Syndra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Lissandra Build Against Syndra

Spellslinger's Shoes is the optimal boots choice against Syndra, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Syndra are Shadowflame, Zhonya's Hourglass and Malignance. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. This build has a 20.0% win rate across 5 games. While the overall matchup may be difficult, this item path gives Lissandra the best chance to compete against Syndra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Syndra matchup.

Early Game vs Late Game

Early Game
Lissandra
54.5%
+9.1% advantage
Lissandra early game win rateLissandra54.5%
Syndra early game win rateSyndra45.5%
Late Game
Syndra
71.4%
+42.9% advantage
Lissandra late game win rateLissandra28.6%
Syndra late game win rateSyndra71.4%

Lissandra dominates the early game (first 15 minutes) with a commanding 54.5% win rate — a 9.1 percentage point lead over Syndra. This lopsided early game means Lissandra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Syndra is far superior in the late game (25+ minutes), boasting a 71.4% win rate — 42.9 points above Lissandra. Extended games heavily favor Syndra, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Lissandra must aggressively press their early advantage and close out the game before Syndra reaches their scaling breakpoints. If Syndra survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Lissandra Runes Against Syndra

Domination rune tree - Lissandra primary runes vs SyndraDomination
Electrocute - best Lissandra rune vs SyndraCheap Shot - best Lissandra rune vs SyndraGrisly Mementos - best Lissandra rune vs SyndraUltimate Hunter - best Lissandra rune vs Syndra
Sorcery rune tree - Lissandra secondary runes vs SyndraSorcery
Manaflow Band - best Lissandra rune vs SyndraTranscendence - best Lissandra rune vs Syndra
62.5% WR

The Domination and Sorcery rune setup gives Lissandra the best tools to compete against Syndra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Lissandra matchup data for League of Legends patch 26.7. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
60.00%1306.883712,37853.6%64.9%
57.52%1136.882011,83565.2%52.2%
50.00%766.890711,85747.2%52.5%
45.95%746.778211,93537.5%52.4%
47.95%736.982512,39648.3%47.7%
52.11%717.081212,61135.7%62.8%
53.62%696.788911,32658.1%50.0%
54.55%666.798912,99555.2%54.0%
50.00%626.990112,04736.7%62.5%
54.10%616.687711,06545.5%64.3%
57.38%616.276711,40053.6%60.6%
34.48%586.766810,83031.4%39.1%
40.00%556.372811,33333.3%45.2%
46.94%496.975711,65340.0%51.7%
50.00%486.776511,97850.0%50.0%
50.00%406.476411,31941.2%56.5%
65.00%407.283311,56863.6%66.7%
56.41%397.084511,79244.4%66.7%
60.00%356.876110,99150.0%70.6%
48.57%356.881511,55440.0%55.0%
36.36%336.784111,39846.7%27.8%
21.21%336.478711,43923.1%20.0%
63.33%307.380811,58476.5%46.1%
62.07%297.188313,06883.3%47.1%
58.62%296.596211,72763.6%55.6%
53.57%286.983410,91262.5%41.7%
46.43%286.68679,78147.1%45.5%
53.57%286.881411,53950.0%56.3%
59.26%277.079712,15157.1%61.5%
69.23%266.586913,22971.4%68.4%
57.69%266.679612,06775.0%42.9%
40.00%257.276711,82854.5%28.6%
64.00%256.680511,12450.0%73.3%
41.67%246.992712,63340.0%42.9%
66.67%247.178811,24454.5%76.9%
73.68%197.196712,77550.0%90.9%
44.44%187.31,06512,47460.0%25.0%
64.71%177.290311,48980.0%42.9%
33.33%156.473710,70622.2%50.0%
57.14%146.289412,26342.9%71.4%
42.86%147.375110,43150.0%25.0%
76.92%136.783113,11175.0%77.8%
38.46%136.082212,47860.0%25.0%
30.77%136.896711,40720.0%37.5%
15.38%136.584811,09216.7%14.3%
45.45%116.480812,11440.0%50.0%
27.27%116.792811,21620.0%33.3%
54.55%116.888611,95450.0%57.1%
40.00%106.882512,83166.7%28.6%
50.00%106.452910,44128.6%100.0%
55.56%96.295114,28150.0%57.1%
88.89%97.280612,70675.0%100.0%
55.56%97.288211,46775.0%40.0%
55.56%95.672312,03950.0%60.0%
55.56%97.786112,78766.7%50.0%
75.00%87.487510,71080.0%66.7%
57.14%77.387510,78575.0%33.3%
42.86%75.873510,32566.7%25.0%
85.71%77.087111,26283.3%100.0%
71.43%76.173511,33280.0%50.0%
50.00%61.761410,6240.0%60.0%
83.33%67.91,14313,99850.0%100.0%
33.33%67.796512,2420.0%66.7%
33.33%66.686711,32825.0%50.0%
50.00%62.45439,94466.7%33.3%
83.33%67.183312,020100.0%80.0%
16.67%67.26078,27816.7%0.0%
60.00%56.01,16411,19766.7%50.0%
40.00%53.07276,78640.0%0.0%
20.00%57.793410,62525.0%0.0%
20.00%55.05978,21425.0%0.0%
40.00%53.45178,76125.0%100.0%
80.00%55.064712,91850.0%100.0%
40.00%56.783411,7270.0%66.7%
60.00%56.077611,837100.0%33.3%
40.00%56.374111,1560.0%50.0%
60.00%56.897912,10050.0%66.7%
80.00%56.51,08510,600100.0%66.7%

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Lissandra vs Syndra - Frequently Asked Questions

How does Lissandra do against Syndra in League of Legends?

Syndra wins the Lissandra vs Syndra matchup with a 60.0% win rate compared to Lissandra's 40.0%, a 20.0 percentage point difference. This data is based on 25 recent ranked games in patch 26.7.

How does Lissandra do against Syndra in the early game?

In the early game, Lissandra has the advantage against Syndra with a 54.5% win rate versus 45.5%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Syndra in the late game?

In the late game, Syndra takes over the Lissandra vs Syndra matchup with a 71.4% win rate compared to 28.6%. Syndra scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Syndra matchup?

Syndra wins the matchup against Lissandra with a 60.0% win rate in League of Legends patch 26.7. The 20.0 percentage point advantage means Syndra is significantly favored in this lane matchup based on 25 games analyzed.

What is the best Lissandra build against Syndra?

The best Lissandra build against Syndra includes Shadowflame, Zhonya's Hourglass, Malignance with Spellslinger's Shoes. This build achieves a 20.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Syndra?

The best Lissandra runes against Syndra use the Domination primary tree with Sorcery secondary. This rune setup achieves a 62.5% win rate in the Lissandra vs Syndra matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Syndra?

No, Lissandra struggles against Syndra with only a 40.0% win rate. Syndra has the advantage in this matchup. Lissandra players should focus on safe farming and avoiding extended trades to minimize Syndra's lead.

How do I play Lissandra against Syndra?

When playing Lissandra against Syndra, play cautiously and avoid Syndra's power spikes. Look for jungle assistance and team-dependent plays since Syndra has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.