Karthusvs Miss Fortune
Karthus vs Miss Fortune is a decisive matchup in LoL patch 26.11. Karthus wins with a 55.2% win rate (+10.3%) over Miss Fortune based on 29 games. Karthus wins the early laning phase while Miss Fortune scales better into the late game. Below you'll find the best Karthus build, runes, laning stats, and strategies for the Karthus vs Miss Fortune matchup.
Karthus Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Karthus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Karthus vs Miss Fortune Matchup?
Karthus vs Miss Fortune Matchup Summary
The Karthus vs Miss Fortune matchup is a decisive matchup in League of Legends ranked play. Based on 29 recent matches analyzed, Karthus wins with a 55.2% win rate compared to Miss Fortune's 44.8%, giving Karthus a 10.3 percentage point advantage. Game phase dynamics play a critical role here: Karthus controls the early laning stage, but Miss Fortune outscales as the game goes longer. The matchup shifts dramatically depending on game length — Karthus needs to press advantages before Miss Fortune reaches their power spikes, while Miss Fortune should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Karthus leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Karthus players can confidently pick into Miss Fortune and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Miss Fortune away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Karthus vs Miss Fortune Laning Phase Breakdown
Miss Fortune is favored during the laning phase against Karthus, winning 3 out of 5 key stat categories. Miss Fortune holds advantages in farming, gold income and sustain, making them the stronger laner in this matchup.
Early Game vs Late Game
Karthus66.7%
Miss Fortune33.3%Karthus42.9%Miss Fortune57.1%Karthus dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Miss Fortune. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Miss Fortune is far superior in the late game (25+ minutes), boasting a 57.1% win rate — 14.3 points above Karthus. Extended games heavily favor Miss Fortune, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Karthus must aggressively press their early advantage and close out the game before Miss Fortune reaches their scaling breakpoints. If Miss Fortune survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Karthus Runes Against Miss Fortune
Domination
Precision
Running Domination primary with Precision secondary allows Karthus to press their advantage against Miss Fortune, amplifying the strengths that make this a favorable matchup.
Karthus matchup data for League of Legends patch 26.11. The table below shows Karthus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karthus build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 49.09% | 55 | 1.4 | 1,030 | 12,957 | 47.8% | 50.0% | |
| 43.64% | 55 | 1.7 | 1,170 | 13,037 | 40.0% | 46.7% | |
| 45.10% | 51 | 1.6 | 1,057 | 13,346 | 31.8% | 55.2% | |
| 59.18% | 49 | 6.3 | 1,291 | 13,609 | 50.0% | 65.5% | |
| 52.08% | 48 | 1.5 | 1,259 | 14,655 | 47.1% | 54.8% | |
| 42.22% | 45 | 1.5 | 1,017 | 13,071 | 43.8% | 41.4% | |
| 37.78% | 45 | 1.3 | 1,027 | 12,768 | 40.9% | 34.8% | |
| 64.44% | 45 | 6.5 | 1,326 | 16,022 | 86.7% | 53.3% | |
| 50.00% | 42 | 6.6 | 1,197 | 13,070 | 66.7% | 33.3% | |
| 43.59% | 39 | 6.3 | 1,215 | 13,238 | 50.0% | 36.8% | |
| 57.89% | 38 | 1.4 | 1,263 | 13,760 | 53.3% | 60.9% | |
| 47.37% | 38 | 1.5 | 1,144 | 13,402 | 37.5% | 54.5% | |
| 34.21% | 38 | 1.9 | 1,067 | 12,867 | 40.0% | 30.4% | |
| 43.24% | 37 | 1.8 | 1,212 | 13,463 | 57.1% | 34.8% | |
| 38.24% | 34 | 7.0 | 1,247 | 13,842 | 33.3% | 42.1% | |
| 46.88% | 32 | 1.8 | 1,146 | 12,845 | 38.5% | 52.6% | |
| 43.33% | 30 | 1.8 | 1,294 | 14,569 | 58.3% | 33.3% | |
| 55.17% | 29 | 6.1 | 1,203 | 12,390 | 66.7% | 42.9% | |
| 46.43% | 28 | 1.4 | 1,030 | 12,474 | 53.3% | 38.5% | |
| 57.14% | 28 | 6.6 | 1,423 | 15,214 | 50.0% | 62.5% | |
| 40.74% | 27 | 1.3 | 1,335 | 15,992 | 16.7% | 47.6% | |
| 28.00% | 25 | 1.8 | 1,163 | 13,295 | 30.0% | 26.7% | |
| 66.67% | 24 | 1.6 | 1,146 | 14,337 | 75.0% | 58.3% | |
| 45.45% | 22 | 1.5 | 1,307 | 14,905 | 50.0% | 44.4% | |
| 66.67% | 21 | 2.2 | 1,201 | 13,572 | 77.8% | 58.3% | |
| 55.00% | 20 | 1.6 | 1,267 | 13,968 | 60.0% | 50.0% | |
| 68.42% | 19 | 5.6 | 1,496 | 16,092 | 100.0% | 60.0% | |
| 63.16% | 19 | 1.3 | 1,116 | 14,409 | 62.5% | 63.6% | |
| 38.89% | 18 | 1.5 | 1,448 | 14,535 | 42.9% | 36.4% | |
| 55.56% | 18 | 6.4 | 1,276 | 13,454 | 66.7% | 44.4% | |
| 72.22% | 18 | 5.1 | 1,121 | 11,322 | 60.0% | 87.5% | |
| 35.29% | 17 | 1.5 | 1,056 | 12,455 | 36.4% | 33.3% | |
| 52.94% | 17 | 1.3 | 1,370 | 15,161 | 57.1% | 50.0% | |
| 76.47% | 17 | 6.5 | 1,263 | 15,482 | 80.0% | 75.0% | |
| 47.06% | 17 | 1.5 | 960 | 12,244 | 44.4% | 50.0% | |
| 52.94% | 17 | 6.5 | 1,330 | 13,719 | 66.7% | 45.5% | |
| 43.75% | 16 | 1.4 | 1,244 | 15,497 | 50.0% | 41.7% | |
| 56.25% | 16 | 1.3 | 1,080 | 13,221 | 80.0% | 45.5% | |
| 53.33% | 15 | 5.4 | 1,373 | 13,678 | 75.0% | 45.5% | |
| 35.71% | 14 | 1.6 | 1,239 | 13,567 | 44.4% | 20.0% | |
| 28.57% | 14 | 6.7 | 1,359 | 11,934 | 50.0% | 12.5% | |
| 42.86% | 14 | 2.4 | 1,250 | 14,777 | 40.0% | 44.4% | |
| 50.00% | 14 | 1.6 | 1,082 | 15,541 | 25.0% | 60.0% | |
| 69.23% | 13 | 6.5 | 1,305 | 13,965 | 57.1% | 83.3% | |
| 61.54% | 13 | 6.5 | 1,256 | 12,939 | 60.0% | 62.5% | |
| 53.85% | 13 | 2.5 | 1,052 | 12,276 | 75.0% | 44.4% | |
| 58.33% | 12 | 5.9 | 1,027 | 10,269 | 57.1% | 60.0% | |
| 83.33% | 12 | 1.3 | 1,229 | 13,183 | 80.0% | 85.7% | |
| 50.00% | 12 | 5.4 | 1,340 | 14,967 | 75.0% | 37.5% | |
| 45.45% | 11 | 1.4 | 1,031 | 13,145 | 57.1% | 25.0% | |
| 72.73% | 11 | 1.6 | 1,027 | 12,997 | 100.0% | 57.1% | |
| 27.27% | 11 | 5.9 | 1,132 | 13,232 | 0.0% | 42.9% | |
| 30.00% | 10 | 3.2 | 1,059 | 13,472 | 25.0% | 33.3% | |
| 70.00% | 10 | 7.4 | 1,271 | 15,568 | 100.0% | 57.1% | |
| 70.00% | 10 | 2.9 | 1,144 | 15,271 | 100.0% | 62.5% | |
| 50.00% | 10 | 7.2 | 1,138 | 12,216 | 50.0% | 50.0% | |
| 40.00% | 10 | 2.9 | 1,376 | 15,578 | 0.0% | 44.4% | |
| 55.56% | 9 | 5.5 | 1,266 | 13,151 | 50.0% | 60.0% | |
| 33.33% | 9 | 4.9 | 927 | 10,925 | 20.0% | 50.0% | |
| 44.44% | 9 | 6.2 | 1,072 | 10,467 | 33.3% | 66.7% | |
| 55.56% | 9 | 3.3 | 1,212 | 14,875 | 100.0% | 42.9% | |
| 55.56% | 9 | 1.4 | 1,252 | 15,076 | 100.0% | 42.9% | |
| 77.78% | 9 | 2.9 | 1,165 | 14,153 | 66.7% | 83.3% | |
| 33.33% | 9 | 2.1 | 1,195 | 13,834 | 33.3% | 33.3% | |
| 87.50% | 8 | 1.3 | 1,113 | 14,337 | 80.0% | 100.0% | |
| 25.00% | 8 | 1.3 | 1,285 | 13,222 | 50.0% | 16.7% | |
| 87.50% | 8 | 6.4 | 1,182 | 14,464 | 50.0% | 100.0% | |
| 75.00% | 8 | 1.7 | 1,650 | 16,965 | 50.0% | 83.3% | |
| 75.00% | 8 | 6.7 | 1,197 | 15,023 | 75.0% | 75.0% | |
| 62.50% | 8 | 2.0 | 991 | 13,519 | 100.0% | 50.0% | |
| 37.50% | 8 | 1.7 | 996 | 13,524 | 0.0% | 50.0% | |
| 57.14% | 7 | 6.3 | 1,632 | 17,174 | 100.0% | 50.0% | |
| 42.86% | 7 | 2.9 | 1,108 | 11,950 | 25.0% | 66.7% | |
| 14.29% | 7 | 1.1 | 907 | 12,626 | 25.0% | 0.0% | |
| 71.43% | 7 | 6.9 | 1,202 | 14,284 | 50.0% | 80.0% | |
| 85.71% | 7 | 5.5 | 1,332 | 17,108 | 0.0% | 85.7% | |
| 42.86% | 7 | 4.1 | 1,210 | 13,964 | 0.0% | 50.0% | |
| 28.57% | 7 | 6.0 | 1,442 | 13,367 | 0.0% | 40.0% | |
| 57.14% | 7 | 7.0 | 1,427 | 13,690 | 33.3% | 75.0% | |
| 57.14% | 7 | 2.4 | 1,124 | 12,107 | 40.0% | 100.0% | |
| 85.71% | 7 | 1.0 | 1,062 | 14,104 | 50.0% | 100.0% | |
| 50.00% | 6 | 7.1 | 1,388 | 12,743 | 50.0% | 50.0% | |
| 33.33% | 6 | 6.8 | 1,144 | 11,486 | 0.0% | 66.7% | |
| 66.67% | 6 | 4.2 | 1,440 | 15,135 | 100.0% | 60.0% | |
| 33.33% | 6 | 2.3 | 965 | 9,779 | 0.0% | 50.0% | |
| 33.33% | 6 | 2.5 | 1,074 | 12,120 | 50.0% | 0.0% | |
| 33.33% | 6 | 6.6 | 1,316 | 11,448 | 0.0% | 66.7% | |
| 16.67% | 6 | 5.8 | 1,303 | 13,270 | 0.0% | 25.0% | |
| 50.00% | 6 | 2.5 | 1,437 | 16,735 | 0.0% | 75.0% | |
| 20.00% | 5 | 6.3 | 1,409 | 13,939 | 0.0% | 33.3% | |
| 40.00% | 5 | 5.3 | 798 | 6,518 | 0.0% | 100.0% | |
| 40.00% | 5 | 1.1 | 1,418 | 14,804 | 0.0% | 50.0% | |
| 40.00% | 5 | 3.4 | 1,190 | 15,035 | 0.0% | 50.0% | |
| 60.00% | 5 | 4.6 | 1,656 | 13,732 | 66.7% | 50.0% | |
| 80.00% | 5 | 6.7 | 1,331 | 10,470 | 66.7% | 100.0% | |
| 60.00% | 5 | 2.0 | 1,292 | 14,405 | 100.0% | 50.0% | |
| 20.00% | 5 | 6.0 | 1,206 | 10,846 | 33.3% | 0.0% | |
| 40.00% | 5 | 6.7 | 1,012 | 12,710 | 0.0% | 50.0% | |
| 40.00% | 5 | 6.3 | 1,482 | 13,690 | 100.0% | 25.0% | |
| 60.00% | 5 | 5.9 | 1,400 | 13,383 | 66.7% | 50.0% | |
| 40.00% | 5 | 6.5 | 1,189 | 9,677 | 25.0% | 100.0% | |
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Karthus vs Miss Fortune - Frequently Asked Questions
How does Karthus do against Miss Fortune in League of Legends?
Karthus wins the Karthus vs Miss Fortune matchup with a 55.2% win rate compared to Miss Fortune's 44.8%, a 10.3 percentage point difference. This data is based on 29 recent ranked games in patch 26.11.
How does Karthus do against Miss Fortune in the early game?
In the early game, Karthus has the advantage against Miss Fortune with a 66.7% win rate versus 33.3%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Karthus do against Miss Fortune in the late game?
In the late game, Miss Fortune takes over the Karthus vs Miss Fortune matchup with a 57.1% win rate compared to 42.9%. Miss Fortune scales better into team fights and objective contests after 25 minutes.
Who wins the Karthus vs Miss Fortune matchup?
Karthus wins the matchup against Miss Fortune with a 55.2% win rate in League of Legends patch 26.11. The 10.3 percentage point advantage means Karthus is significantly favored in this lane matchup based on 29 games analyzed.
What is the best Karthus build against Miss Fortune?
The best Karthus build against Miss Fortune includes optimized core items. Check the matchup breakdown above for the full item path and build order.
What are the best Karthus runes against Miss Fortune?
The best Karthus runes against Miss Fortune use the Domination primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Karthus vs Miss Fortune matchup. See the full rune breakdown in the matchup comparison above.
Does Karthus counter Miss Fortune?
Yes, Karthus has a favorable matchup against Miss Fortune with a 55.2% win rate. Karthus strongly counters Miss Fortune in lane based on current patch 26.11 data.
How do I play Karthus against Miss Fortune?
When playing Karthus against Miss Fortune, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.