Pantheon - League of Legends Champion
Win Rate
49.7%
Pick Rate
3.6%

Pantheonvs Syndra

CFighterAssassin
Patch26.3
Matches785,220
LaneAll Lanes
TierAll Tiers
Last UpdatedFeb 26, 2026
MethodologyData Methodology

Pantheon vs Syndra is a decisive matchup in LoL patch 26.3. Pantheon wins with a 58.3% win rate (+16.7%) over Syndra based on 12 games. Pantheon wins the early laning phase while Syndra scales better into the late game. Below you'll find the best Pantheon build, runes, laning stats, and strategies for the Pantheon vs Syndra matchup.

Pantheon Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Pantheon performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Syndra - 58.3% win rateSyndra(58.3%)
Pantheon - 58.3% win rate in this matchup
Pantheon
58.3% WR
VS
Syndra vs Pantheon matchup - 41.7% win rate
Syndra
41.7% WR

Who Wins the Pantheon vs Syndra Matchup?

Pantheon wins the Pantheon vs Syndra matchup
Winner
Pantheon
Matches: 12
58.3%
Win Rate
41.7%
4.8
CS / min
6.2
677
DMG / min
930
11,168
Gold / game
12,423
192
Heal / min
87
737
DMG Mitigated / min
354
0.7
CC / min
1.4
83.3%
Early Game WR
16.7%
33.3%
Late Game WR
66.7%

Pantheon vs Syndra Matchup Summary

The Pantheon vs Syndra matchup is a decisive matchup in League of Legends ranked play. Based on 12 recent matches analyzed, Pantheon wins with a 58.3% win rate compared to Syndra's 41.7%, giving Pantheon a 16.7 percentage point advantage. Game phase dynamics play a critical role here: Pantheon controls the early laning stage, but Syndra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Pantheon needs to press advantages before Syndra reaches their power spikes, while Syndra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Pantheon leads by 488 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Pantheon players can confidently pick into Syndra and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Syndra away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Pantheon vs Syndra Laning Phase Breakdown

Syndra wins the laning phase against Pantheon in League of Legends

Syndra is favored during the laning phase against Pantheon, winning 4 out of 5 key stat categories. Syndra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
4.8Pantheon
6.2Syndra
Syndra significantly out-farms Pantheon by 1.3 CS per minute, accumulating an estimated 20 CS lead by mid game. This substantial farming gap gives Syndra a major gold advantage and earlier item completions. Pantheon players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
677Pantheon
930Syndra
Syndra heavily out-damages Pantheon by 253 DMG/min, dominating both short trades and all-in fights. Pantheon should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Syndra's sustained damage advantage take over.
Economy
11,168Pantheon
12,423Syndra
Syndra generates a commanding 1,255 more gold per game than Pantheon. This substantial economic advantage means Syndra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Pantheon should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.7Pantheon
1.4Syndra
Syndra provides 0.7 seconds more crowd control per minute than Pantheon, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Syndra coordinate with their jungler and control the pace of skirmishes.
Sustain
929Pantheon
441Syndra
Pantheon vastly out-sustains Syndra, healing and mitigating 488 more damage per minute. This massive durability gap means Pantheon can absorb significant punishment and remain in lane while Syndra is forced to recall. Building grievous wounds early is essential for Syndra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Pantheon Build Against Syndra

Swiftmarch is the optimal boots choice against Syndra, providing the mobility and stats Pantheon needs most in this matchup. The top-performing core items for Pantheon against Syndra are Opportunity, Youmuu's Ghostblade and Black Cleaver. This combination gives Pantheon an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Pantheon vs Syndra matchup.

Early Game vs Late Game

Early Game
Pantheon
83.3%
+66.7% advantage
Pantheon early game win ratePantheon83.3%
Syndra early game win rateSyndra16.7%
Late Game
Syndra
66.7%
+33.3% advantage
Pantheon late game win ratePantheon33.3%
Syndra late game win rateSyndra66.7%

Pantheon dominates the early game (first 15 minutes) with a commanding 83.3% win rate — a 66.7 percentage point lead over Syndra. This lopsided early game means Pantheon can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Syndra is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Pantheon. Extended games heavily favor Syndra, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Pantheon must aggressively press their early advantage and close out the game before Syndra reaches their scaling breakpoints. If Syndra survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Pantheon Runes Against Syndra

Precision rune tree - Pantheon primary runes vs SyndraPrecision
Conqueror - best Pantheon rune vs SyndraPresence of Mind - best Pantheon rune vs SyndraLegend: Alacrity - best Pantheon rune vs SyndraCut Down - best Pantheon rune vs Syndra
Inspiration rune tree - Pantheon secondary runes vs SyndraInspiration
Biscuit Delivery - best Pantheon rune vs SyndraCosmic Insight - best Pantheon rune vs Syndra
100.0% WR

Running Precision primary with Inspiration secondary allows Pantheon to press their advantage against Syndra, amplifying the strengths that make this a favorable matchup.


Pantheon matchup data for League of Legends patch 26.3. The table below shows Pantheon's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Pantheon build, runes, laning stats, and early vs late game analysis for that specific matchup.

Pantheon matchup win rates and stats in League of Legends patch 26.3
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
51.14%1761.968611,13549.3%52.4%
50.36%1391.568410,51150.0%50.6%
49.22%1281.768610,52155.2%44.3%
47.66%1281.465010,16846.0%49.2%
44.09%1271.567610,05745.2%43.1%
59.63%1095.590212,57053.2%64.5%
51.46%1031.771711,14053.2%50.0%
56.04%911.66719,83858.7%53.3%
54.76%845.593411,43150.0%60.0%
41.67%842.373711,35346.7%38.9%
35.37%821.669410,95140.5%31.1%
55.84%771.771910,90447.2%63.4%
44.16%771.666710,64856.8%32.5%
57.53%734.175411,35659.5%55.6%
45.83%722.580311,06542.4%48.7%
42.25%715.591411,49544.1%40.5%
53.52%711.66139,44063.2%42.4%
44.12%682.981812,73142.3%45.2%
40.30%671.66509,99543.8%37.1%
49.25%674.078211,27051.6%47.2%
52.31%652.991111,56157.1%48.6%
57.81%642.474911,91276.2%48.8%
43.75%641.578111,51360.0%33.3%
42.86%631.465310,33141.4%44.1%
41.94%621.173412,73339.3%44.1%
45.90%615.11,06411,83368.0%30.6%
37.70%611.667611,23922.7%46.1%
40.98%615.788911,58842.3%40.0%
53.33%601.975511,81350.0%56.3%
33.90%591.46599,22335.5%32.1%
58.62%581.671811,38550.0%65.6%
43.86%574.01,06311,68037.9%50.0%
46.43%561.664510,50846.4%46.4%
50.00%564.484112,30456.5%45.5%
61.82%554.81,00112,09166.7%56.0%
46.30%542.777012,23538.5%53.6%
50.94%535.999712,35950.0%52.2%
48.08%522.383812,87533.3%58.1%
51.92%525.591511,90842.9%58.1%
46.15%524.61,04712,02254.2%39.3%
53.85%521.461010,27152.0%55.6%
56.00%502.680111,35656.5%55.6%
54.00%505.484611,23548.0%60.0%
48.94%475.491911,04344.0%54.5%
48.89%451.272712,55546.7%50.0%
50.00%441.367812,47246.7%51.7%
54.55%444.385012,70842.1%64.0%
50.00%423.675511,30031.3%61.5%
53.66%412.671311,11643.8%60.0%
46.15%394.584312,61050.0%43.5%
53.85%395.281410,65461.9%44.4%
51.28%391.675710,16455.0%47.4%
52.63%382.279110,69454.5%50.0%
63.16%382.379911,75359.1%68.8%
37.84%373.983611,70021.4%47.8%
54.05%375.297912,25652.9%55.0%
64.86%375.092010,51857.9%72.2%
50.00%365.081511,61561.5%43.5%
54.29%354.086612,89058.3%52.2%
57.14%355.599112,12466.7%47.1%
52.94%343.977111,81842.9%60.0%
38.24%341.572610,70642.9%35.0%
55.88%345.096311,83562.5%50.0%
33.33%333.875511,09540.0%27.8%
68.75%323.294011,90878.6%61.1%
41.94%315.989411,57538.9%46.1%
54.84%311.573711,56354.5%55.0%
54.84%311.974010,65746.7%62.5%
45.16%311.068312,71950.0%42.1%
63.33%304.894811,53475.0%50.0%
51.72%291.573912,23460.0%50.0%
48.28%295.41,07812,20060.0%42.1%
42.86%281.072312,47133.3%53.9%
42.86%285.289112,50546.1%40.0%
71.43%285.098212,92983.3%62.5%
35.71%281.778211,69042.9%28.6%
42.86%284.682810,44550.0%30.0%
51.85%271.86819,96556.3%45.5%
55.56%275.880611,09850.0%60.0%
74.07%271.57439,78778.6%69.2%
57.69%265.485611,76454.5%60.0%
46.15%265.997511,18146.1%46.1%
43.48%231.573510,52855.6%35.7%
60.87%235.38939,29575.0%28.6%
59.09%221.173912,30364.3%50.0%
27.27%221.367913,14937.5%21.4%
59.09%221.269112,71962.5%57.1%
66.67%211.672511,74580.0%54.5%
76.19%211.271411,95688.9%66.7%
61.90%211.481913,07060.0%63.6%
60.00%201.373512,15562.5%58.3%
45.00%201.670312,36344.4%45.5%
30.00%205.174010,21228.6%33.3%
42.11%195.793911,44040.0%44.4%
31.58%194.463610,75220.0%44.4%
42.11%195.480411,49955.6%30.0%
44.44%183.085112,62360.0%25.0%
33.33%186.097614,47240.0%30.8%
55.56%184.685811,90362.5%50.0%
66.67%182.473012,04566.7%66.7%
55.56%185.179211,09350.0%60.0%
44.44%185.079112,08562.5%30.0%
52.94%174.585011,51828.6%70.0%
29.41%171.073213,00516.7%36.4%
29.41%175.590112,73120.0%33.3%
41.18%175.879911,31714.3%60.0%
52.94%173.488411,36150.0%53.9%
64.71%171.172613,22583.3%54.5%
52.94%172.272511,65650.0%55.6%
68.75%163.983612,74540.0%81.8%
68.75%160.873012,74966.7%70.0%
50.00%164.577012,00525.0%75.0%
40.00%153.76829,87237.5%42.9%
60.00%151.975713,58250.0%63.6%
21.43%141.684312,47111.1%40.0%
21.43%144.275310,22214.3%28.6%
50.00%145.61,02510,84344.4%60.0%
42.86%145.51,01212,35560.0%33.3%
53.85%131.265011,85366.7%50.0%
53.85%135.495510,39142.9%66.7%
46.15%131.870012,26333.3%50.0%
61.54%130.971812,27785.7%33.3%
75.00%125.378710,58083.3%66.7%
58.33%124.867711,16883.3%33.3%
58.33%123.477311,53060.0%57.1%
50.00%125.595011,80157.1%40.0%
58.33%125.176611,84540.0%71.4%
66.67%121.471612,89975.0%62.5%
36.36%114.678312,6500.0%66.7%
72.73%115.397611,90166.7%80.0%
54.55%111.992614,97833.3%62.5%
63.64%114.784912,28260.0%66.7%
50.00%105.477311,89450.0%50.0%
50.00%104.884812,40450.0%50.0%
50.00%104.01,05014,487100.0%44.4%
40.00%100.65128,04342.9%33.3%
50.00%104.475412,29966.7%42.9%
55.56%93.285712,19866.7%33.3%
33.33%94.268013,07233.3%33.3%
77.78%94.092114,622100.0%66.7%
44.44%91.573010,94025.0%60.0%
33.33%92.361310,5350.0%50.0%
44.44%94.36259,98780.0%0.0%
22.22%93.983612,14540.0%0.0%
62.50%85.076910,07050.0%75.0%
87.50%85.291013,08750.0%100.0%
50.00%81.384716,6210.0%57.1%
50.00%84.979411,35325.0%75.0%
57.14%71.770712,4860.0%66.7%
71.43%70.681110,17975.0%66.7%
42.86%74.974810,55675.0%0.0%
66.67%60.891916,20550.0%75.0%
16.67%62.38089,5200.0%33.3%
33.33%65.08639,71133.3%33.3%
33.33%64.390815,7640.0%50.0%
16.67%63.071810,48233.3%0.0%
66.67%63.498711,97866.7%66.7%
40.00%54.285311,41250.0%33.3%
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Pantheon vs Syndra - Frequently Asked Questions

How does Pantheon do against Syndra in League of Legends?

Pantheon wins the Pantheon vs Syndra matchup with a 58.3% win rate compared to Syndra's 41.7%, a 16.7 percentage point difference. This data is based on 12 recent ranked games in patch 26.3.

How does Pantheon do against Syndra in the early game?

In the early game, Pantheon has the advantage against Syndra with a 83.3% win rate versus 16.7%. Pantheon players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Pantheon do against Syndra in the late game?

In the late game, Syndra takes over the Pantheon vs Syndra matchup with a 66.7% win rate compared to 33.3%. Syndra scales better into team fights and objective contests after 25 minutes.

Who wins the Pantheon vs Syndra matchup?

Pantheon wins the matchup against Syndra with a 58.3% win rate in League of Legends patch 26.3. The 16.7 percentage point advantage means Pantheon is significantly favored in this lane matchup based on 12 games analyzed.

What is the best Pantheon build against Syndra?

The best Pantheon build against Syndra includes Opportunity, Youmuu's Ghostblade, Black Cleaver with Swiftmarch. Check the matchup breakdown above for the full item path and build order.

What are the best Pantheon runes against Syndra?

The best Pantheon runes against Syndra use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Pantheon vs Syndra matchup. See the full rune breakdown in the matchup comparison above.

Does Pantheon counter Syndra?

Yes, Pantheon has a favorable matchup against Syndra with a 58.3% win rate. Pantheon strongly counters Syndra in lane based on current patch 26.3 data.

How do I play Pantheon against Syndra?

When playing Pantheon against Syndra, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.