Pantheon - League of Legends Champion
Win Rate
49.4%
Pick Rate
4.1%

Pantheonvs Syndra

DFighterAssassin
Patch26.10
Matches3,013,751
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 28, 2026
MethodologyData Methodology

Pantheon vs Syndra is a decisive matchup in LoL patch 26.10. Syndra wins with a 60.0% win rate (+20.0%) over Pantheon based on 10 games. Pantheon wins the early laning phase while Syndra scales better into the late game. Below you'll find the best Pantheon build, runes, laning stats, and strategies for the Pantheon vs Syndra matchup.

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Pantheon Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Pantheon performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Pantheon - 40.0% win rate in this matchup
Pantheon
40.0% WR
VS
Syndra vs Pantheon matchup - 60.0% win rate
Syndra
60.0% WR

Who Wins the Pantheon vs Syndra Matchup?

Syndra wins the Pantheon vs Syndra matchup
Winner
Syndra
Matches: 10
40.0%
Win Rate
60.0%
5.1
CS / min
6.5
730
DMG / min
895
12,252
Gold / game
13,469
188
Heal / min
73
771
DMG Mitigated / min
315
0.6
CC / min
1.5
50.0%
Early Game WR
50.0%
33.3%
Late Game WR
66.7%

Pantheon vs Syndra Matchup Summary

The Pantheon vs Syndra matchup is a decisive matchup in League of Legends ranked play. Based on 10 recent matches analyzed, Syndra wins with a 60.0% win rate compared to Pantheon's 40.0%, giving Syndra a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Pantheon controls the early laning stage, but Syndra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Pantheon needs to press advantages before Syndra reaches their power spikes, while Syndra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Pantheon leads by 571 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra has a strong advantage in this matchup. Pantheon players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Syndra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Pantheon vs Syndra Laning Phase Breakdown

Syndra wins the laning phase against Pantheon in League of Legends

Syndra is favored during the laning phase against Pantheon, winning 4 out of 5 key stat categories. Syndra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
5.1Pantheon
6.5Syndra
Syndra significantly out-farms Pantheon by 1.4 CS per minute, accumulating an estimated 21 CS lead by mid game. This substantial farming gap gives Syndra a major gold advantage and earlier item completions. Pantheon players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
730Pantheon
895Syndra
Syndra heavily out-damages Pantheon by 166 DMG/min, dominating both short trades and all-in fights. Pantheon should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Syndra's sustained damage advantage take over.
Economy
12,252Pantheon
13,469Syndra
Syndra generates a commanding 1,217 more gold per game than Pantheon. This substantial economic advantage means Syndra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Pantheon should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.6Pantheon
1.5Syndra
Syndra brings significantly more crowd control than Pantheon, with 0.9 more seconds of CC per minute. This large utility gap makes Syndra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Pantheon should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
959Pantheon
388Syndra
Pantheon vastly out-sustains Syndra, healing and mitigating 571 more damage per minute. This massive durability gap means Pantheon can absorb significant punishment and remain in lane while Syndra is forced to recall. Building grievous wounds early is essential for Syndra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Pantheon Build Against Syndra

Crimson Lucidity is the optimal boots choice against Syndra, providing the mobility and stats Pantheon needs most in this matchup. The top-performing core items for Pantheon against Syndra are Voltaic Cyclosword, Profane Hydra and Serylda's Grudge. This combination gives Pantheon an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Syndra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Pantheon vs Syndra matchup.

Early Game vs Late Game

Early Game
Pantheon
50.0%
+0.0% advantage
Pantheon early game win ratePantheon50.0%
Syndra early game win rateSyndra50.0%
Late Game
Syndra
66.7%
+33.3% advantage
Pantheon late game win ratePantheon33.3%
Syndra late game win rateSyndra66.7%

The early game (first 15 minutes) is a toss-up between Pantheon and Syndra, with Pantheon holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Syndra is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Pantheon. Extended games heavily favor Syndra, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Pantheon has the edge early, but Syndra gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Pantheon Runes Against Syndra

Domination rune tree - Pantheon primary runes vs SyndraDomination
Electrocute - best Pantheon rune vs SyndraSudden Impact - best Pantheon rune vs SyndraSixth Sense - best Pantheon rune vs SyndraTreasure Hunter - best Pantheon rune vs Syndra
Inspiration rune tree - Pantheon secondary runes vs SyndraInspiration
Cash Back - best Pantheon rune vs SyndraCosmic Insight - best Pantheon rune vs Syndra
100.0% WR

The Domination and Inspiration rune setup gives Pantheon the best tools to compete against Syndra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Pantheon matchup data for League of Legends patch 26.10. The table below shows Pantheon's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Pantheon build, runes, laning stats, and early vs late game analysis for that specific matchup.

Pantheon matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
44.44%2611.966410,16543.3%45.4%
43.61%2271.569410,13842.4%44.5%
45.83%1921.666310,41045.3%46.1%
46.39%1661.668310,42240.0%51.0%
49.40%1661.667910,22561.5%38.6%
47.53%1621.666310,39746.8%48.0%
52.56%1561.872410,42654.0%51.6%
46.41%1531.671210,50157.4%37.6%
50.75%1344.585212,18157.5%47.1%
49.22%1282.073210,66244.7%51.9%
47.62%1261.674611,45066.0%36.7%
58.82%1195.290311,70471.1%51.4%
50.49%1032.482010,71250.0%51.0%
50.49%1035.692311,85856.5%45.6%
50.49%1035.897311,56359.1%44.1%
53.92%1025.291211,25153.7%54.1%
56.00%1001.571310,63854.8%56.9%
52.08%964.997411,87760.0%43.5%
55.17%871.968911,19852.6%57.1%
50.57%871.680412,79542.9%55.8%
51.72%871.571810,51247.1%54.7%
44.19%862.376010,13835.6%53.7%
56.47%851.56059,57264.6%46.0%
43.90%825.299511,50550.0%38.1%
51.22%822.677110,84258.8%45.8%
52.50%801.567810,22851.4%53.3%
40.51%791.56509,95844.1%37.8%
43.59%781.662110,22346.1%41.0%
41.56%775.390911,45129.4%51.2%
46.75%771.569910,14748.6%45.2%
55.26%764.074910,67250.0%60.0%
45.33%755.21,11011,75551.6%40.9%
44.00%751.077813,54433.3%49.0%
45.83%725.698912,06451.7%41.9%
42.25%711.372912,52340.0%43.1%
50.00%681.581512,62957.7%45.2%
52.24%672.379211,11154.8%50.0%
50.75%672.990812,60248.1%52.5%
40.91%661.867811,16344.0%39.0%
54.55%661.76629,70255.3%53.6%
59.38%644.289412,55063.6%57.1%
40.98%611.667710,92242.3%40.0%
48.33%603.190612,14653.3%43.3%
50.00%601.874811,51850.0%50.0%
43.33%603.483611,70736.4%47.4%
48.33%605.01,10210,45241.2%57.7%
49.15%595.186911,51143.8%55.6%
50.00%584.786811,91663.6%41.7%
50.88%571.368511,38447.4%52.6%
42.11%574.973111,02138.5%45.2%
52.63%571.574710,47953.9%51.6%
46.43%561.270211,72552.0%41.9%
43.64%554.580110,10142.9%44.1%
61.82%555.086210,71170.0%52.0%
33.33%545.390411,96741.7%26.7%
46.30%541.162611,00646.7%45.8%
37.74%532.673111,01933.3%40.0%
61.54%520.976512,30450.0%70.0%
44.23%525.180212,42344.4%44.1%
37.25%510.964112,08430.0%41.9%
45.10%515.099311,43247.4%43.8%
43.75%484.180812,45437.5%45.0%
43.75%485.28199,73833.3%54.2%
44.68%473.376711,77447.8%41.7%
46.67%453.283812,46142.1%50.0%
29.55%445.676910,18936.0%21.1%
43.18%445.275511,31733.3%50.0%
52.27%445.893510,85352.4%52.2%
47.73%445.795411,36554.5%40.9%
36.36%441.067411,49626.3%44.0%
46.51%433.477310,79236.4%57.1%
37.21%433.189912,50928.6%45.5%
51.22%415.694011,63852.6%50.0%
24.39%411.972810,93616.7%27.6%
48.78%415.781511,80042.9%51.9%
52.50%401.76919,33375.0%30.0%
40.00%405.887210,98441.7%37.5%
61.54%395.21,02911,50852.9%68.2%
58.97%395.787511,35566.7%54.2%
42.11%385.21,01911,60342.1%42.1%
39.47%381.566310,25938.9%40.0%
64.86%372.073510,14461.9%68.8%
55.56%363.675010,56757.9%52.9%
44.44%364.388610,87240.0%47.6%
44.44%365.495111,99350.0%41.7%
55.88%344.985011,59040.0%68.4%
44.12%341.46709,95242.9%45.0%
54.55%331.46159,02873.7%28.6%
45.45%331.173811,74746.7%44.4%
46.88%323.166111,26966.7%35.0%
34.38%321.169912,61128.6%38.9%
35.48%313.985310,46528.6%41.2%
33.33%305.286611,55935.7%31.3%
43.33%304.081211,47957.1%31.3%
36.67%305.576310,21712.5%64.3%
50.00%302.578613,79228.6%56.5%
51.72%295.898211,48141.7%58.8%
28.57%281.86519,24835.7%21.4%
62.96%273.180811,98037.5%73.7%
37.04%275.41,02912,71141.7%33.3%
55.56%270.978413,18533.3%66.7%
59.26%274.791011,46661.5%57.1%
51.85%272.177011,51436.4%62.5%
70.37%275.482610,38376.9%64.3%
55.56%275.785210,73460.0%50.0%
64.00%250.877213,12054.5%71.4%
64.00%255.591611,64355.6%68.8%
58.33%243.989610,74864.3%50.0%
62.50%241.365910,48366.7%55.6%
56.52%245.690112,08454.5%58.3%
56.52%232.580711,96444.4%64.3%
56.52%232.179811,66250.0%63.6%
52.17%235.184912,09140.0%61.5%
52.17%235.51,08710,51764.3%33.3%
40.91%220.878712,48244.4%38.5%
40.91%223.98959,97127.3%54.5%
40.91%223.576510,23240.0%41.7%
50.00%220.984711,90350.0%50.0%
38.10%210.869711,57144.4%33.3%
52.38%211.26349,55946.1%62.5%
35.00%204.883511,71537.5%33.3%
50.00%205.294512,05044.4%54.5%
75.00%205.194211,72488.9%63.6%
52.63%191.178712,68257.1%50.0%
55.56%185.21,03511,71628.6%72.7%
38.89%185.298612,87650.0%33.3%
55.56%184.286111,75783.3%41.7%
55.56%181.675712,25660.0%53.9%
23.53%171.783011,15233.3%18.2%
41.18%175.688810,46250.0%28.6%
62.50%165.279011,26370.0%50.0%
56.25%161.387311,96640.0%63.6%
56.25%164.375510,93237.5%75.0%
33.33%155.68279,02841.7%0.0%
53.33%154.471710,70850.0%55.6%
42.86%141.66468,37344.4%40.0%
50.00%144.578710,85957.1%42.9%
71.43%143.17149,70877.8%60.0%
61.54%136.075511,97357.1%66.7%
69.23%135.397712,46566.7%71.4%
23.08%131.467513,80725.0%22.2%
46.15%131.156911,39425.0%55.6%
61.54%131.884713,60950.0%66.7%
50.00%124.686213,29550.0%50.0%
72.73%113.779211,84150.0%100.0%
30.00%101.473313,52750.0%16.7%
40.00%105.173012,25250.0%33.3%
88.89%93.176513,68680.0%100.0%
33.33%90.987612,22425.0%40.0%
62.50%84.279211,777100.0%40.0%
75.00%84.774710,387100.0%50.0%
50.00%63.663111,96525.0%100.0%
33.33%64.459312,5430.0%33.3%
33.33%64.796511,69533.3%33.3%
40.00%54.880510,40850.0%33.3%
80.00%53.01,06815,919100.0%75.0%

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Pantheon vs Syndra - Frequently Asked Questions

How does Pantheon do against Syndra in League of Legends?

Syndra wins the Pantheon vs Syndra matchup with a 60.0% win rate compared to Pantheon's 40.0%, a 20.0 percentage point difference. This data is based on 10 recent ranked games in patch 26.10.

How does Pantheon do against Syndra in the early game?

In the early game, Pantheon has the advantage against Syndra with a 50.0% win rate versus 50.0%. Pantheon players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Pantheon do against Syndra in the late game?

In the late game, Syndra takes over the Pantheon vs Syndra matchup with a 66.7% win rate compared to 33.3%. Syndra scales better into team fights and objective contests after 25 minutes.

Who wins the Pantheon vs Syndra matchup?

Syndra wins the matchup against Pantheon with a 60.0% win rate in League of Legends patch 26.10. The 20.0 percentage point advantage means Syndra is significantly favored in this lane matchup based on 10 games analyzed.

What is the best Pantheon build against Syndra?

The best Pantheon build against Syndra includes Voltaic Cyclosword, Profane Hydra, Serylda's Grudge with Crimson Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Pantheon runes against Syndra?

The best Pantheon runes against Syndra use the Domination primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Pantheon vs Syndra matchup. See the full rune breakdown in the matchup comparison above.

Does Pantheon counter Syndra?

No, Pantheon struggles against Syndra with only a 40.0% win rate. Syndra has the advantage in this matchup. Pantheon players should focus on safe farming and avoiding extended trades to minimize Syndra's lead.

How do I play Pantheon against Syndra?

When playing Pantheon against Syndra, play cautiously and avoid Syndra's power spikes. Look for jungle assistance and team-dependent plays since Syndra has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.