Pyke - League of Legends Champion
Win Rate
49.0%
Pick Rate
2.9%

Pykevs Seraphine

DSupportAssassin
Patch26.10
Matches2,379,056
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 26, 2026
MethodologyData Methodology

Pyke vs Seraphine is a moderate matchup in LoL patch 26.10. Seraphine wins with a 51.8% win rate (+3.5%) over Pyke based on 400 games. Pyke wins the early laning phase while Seraphine scales better into the late game. Below you'll find the best Pyke build, runes, laning stats, and strategies for the Pyke vs Seraphine matchup.

Pyke Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Pyke performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 48.3% win rateSeraphine(48.3%)
Pyke - 48.3% win rate in this matchup
Pyke
48.3% WR
VS
Seraphine vs Pyke matchup - 51.8% win rate
Seraphine
51.8% WR

Who Wins the Pyke vs Seraphine Matchup?

Seraphine wins the Pyke vs Seraphine matchup
Winner
Seraphine
Matches: 400
48.3%
Win Rate
51.8%
1.1
CS / min
1.4
493
DMG / min
477
10,235
Gold / game
9,416
192
Heal / min
336
464
DMG Mitigated / min
358
1.0
CC / min
1.1
50.0%
Early Game WR
50.0%
47.1%
Late Game WR
52.9%

Pyke vs Seraphine Matchup Summary

The Pyke vs Seraphine matchup is a moderate matchup in League of Legends ranked play. Based on 400 recent matches analyzed, Seraphine wins with a 51.8% win rate compared to Pyke's 48.3%, giving Seraphine a 3.5 percentage point advantage. Game phase dynamics play a critical role here: Pyke controls the early laning stage, but Seraphine outscales as the game goes longer. The matchup shifts dramatically depending on game length — Pyke needs to press advantages before Seraphine reaches their power spikes, while Seraphine should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in CS, where Seraphine leads by 0.3 CS/min — a difference that heavily influences the outcome of trades and skirmishes. While Seraphine is slightly favored, Pyke can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Seraphine's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Pyke vs Seraphine Laning Phase Breakdown

Seraphine wins the laning phase against Pyke in League of Legends

Seraphine is favored during the laning phase against Pyke, winning 3 out of 5 key stat categories. Seraphine holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.

Farming
1.1Pyke
1.4Seraphine
Seraphine edges out Pyke by 0.3 CS per minute — a moderate farming advantage that adds up to roughly 5 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Seraphine.
Damage
493Pyke
477Seraphine
Damage output is virtually even between Pyke and Seraphine, with only 16 DMG/min separating them. Fights in this matchup are decided more by ability timing and positioning than raw damage numbers, making mechanical skill the deciding factor in trades.
Economy
10,235Pyke
9,416Seraphine
Pyke generates a commanding 819 more gold per game than Seraphine. This substantial economic advantage means Pyke consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Seraphine should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.0Pyke
1.1Seraphine
Both Pyke and Seraphine provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
656Pyke
694Seraphine
Pyke and Seraphine have comparable sustain profiles, with only 38 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Best Pyke Build Against Seraphine

Ionian Boots of Lucidity is the optimal boots choice against Seraphine, providing the mobility and stats Pyke needs most in this matchup. The top-performing core items for Pyke against Seraphine are Axiom Arc, Serpent's Fang and Edge of Night. This combination gives Pyke an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 3 games — well above average and making it the top item path against Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Pyke vs Seraphine matchup.

Early Game vs Late Game

Early Game
Pyke
50.0%
+0.0% advantage
Pyke early game win ratePyke50.0%
Seraphine early game win rateSeraphine50.0%
Late Game
Seraphine
52.9%
+5.9% advantage
Pyke late game win ratePyke47.1%
Seraphine late game win rateSeraphine52.9%

The early game (first 15 minutes) is a toss-up between Pyke and Seraphine, with Pyke holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Seraphine is far superior in the late game (25+ minutes), boasting a 52.9% win rate — 5.9 points above Pyke. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Pyke has the edge early, but Seraphine gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Pyke Runes Against Seraphine

Domination rune tree - Pyke primary runes vs SeraphineDomination
Hail of Blades - best Pyke rune vs SeraphineSudden Impact - best Pyke rune vs SeraphineDeep Ward - best Pyke rune vs SeraphineRelentless Hunter - best Pyke rune vs Seraphine
Sorcery rune tree - Pyke secondary runes vs SeraphineSorcery
Nimbus Cloak - best Pyke rune vs SeraphineCelerity - best Pyke rune vs Seraphine
62.5% WR

The Domination and Sorcery rune setup gives Pyke the best tools to compete against Seraphine in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Pyke matchup data for League of Legends patch 26.10. The table below shows Pyke's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Pyke build, runes, laning stats, and early vs late game analysis for that specific matchup.

Pyke matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
48.25%4001.149310,23550.0%47.1%
49.43%3501.146410,22048.9%49.8%
49.47%2851.14609,95753.6%45.6%
47.08%2741.147110,36053.0%42.8%
50.00%2741.148410,42448.0%51.2%
51.84%2721.04829,99654.6%49.7%
48.73%2361.14879,86950.0%47.7%
57.22%1941.149510,43956.5%57.8%
50.79%1911.150110,87755.9%48.0%
48.54%1711.04819,71851.9%45.6%
49.02%1531.14949,76453.3%44.9%
54.25%1531.152210,73045.0%60.2%
49.67%1511.146710,19845.3%52.9%
48.28%1451.147510,51552.5%45.2%
53.90%1411.14319,37558.6%49.3%
45.86%1331.156411,00443.4%47.5%
52.38%1261.14439,80059.1%45.0%
48.41%1261.14399,95438.5%59.0%
55.65%1241.149610,44952.2%57.7%
46.67%1201.250410,52839.3%53.1%
48.31%1181.148310,57943.8%51.4%
56.90%1161.047010,22364.6%51.5%
47.57%1031.147910,65747.8%47.4%
48.00%1001.151010,63747.5%48.3%
42.22%901.146310,23051.4%35.9%
52.50%801.04689,83854.0%51.2%
50.63%791.14439,90752.4%48.6%
49.37%791.151510,93744.8%52.0%
58.44%771.14689,66553.7%63.9%
43.42%761.247710,31543.3%43.5%
44.78%671.147410,45161.9%37.0%
46.00%501.149110,80843.8%47.1%
51.02%491.143011,41045.5%52.6%
40.91%441.050610,52628.6%52.2%
58.54%411.04679,11955.6%60.9%
37.50%401.346010,39950.0%29.2%
48.57%351.146910,26557.1%42.9%
44.44%271.349710,86950.0%41.2%
57.69%261.350110,78850.0%60.0%
44.00%251.24889,52542.9%45.5%
60.87%231.24699,13953.9%70.0%
68.18%221.14588,02553.3%100.0%
42.86%211.14389,95040.0%45.5%
52.94%171.34589,13750.0%55.6%
80.00%151.342611,26880.0%80.0%
57.14%141.248410,60180.0%44.4%
46.15%131.358611,69366.7%40.0%
33.33%121.14599,28114.3%60.0%
25.00%121.545211,08133.3%22.2%
83.33%121.34629,98650.0%100.0%
63.64%111.54509,97860.0%66.7%
45.45%110.956110,937100.0%25.0%
27.27%112.95019,54714.3%50.0%
72.73%111.153411,517100.0%62.5%
45.45%111.348611,34620.0%66.7%
60.00%101.146610,56280.0%40.0%
60.00%101.34439,49660.0%60.0%
50.00%100.94598,48525.0%66.7%
70.00%101.35069,88060.0%80.0%
66.67%91.351610,54050.0%80.0%
44.44%91.257810,29525.0%60.0%
44.44%91.761411,48250.0%40.0%
44.44%92.64228,98633.3%66.7%
44.44%92.255113,05066.7%33.3%
37.50%81.960511,0070.0%50.0%
37.50%81.34548,44333.3%50.0%
50.00%83.654910,32025.0%75.0%
25.00%81.33999,43050.0%16.7%
42.86%70.94979,57250.0%40.0%
71.43%71.04157,44783.3%0.0%
57.14%71.24779,29950.0%66.7%
66.67%62.970010,15360.0%100.0%
16.67%61.04939,5760.0%25.0%
33.33%62.344110,55433.3%33.3%
66.67%62.650810,99750.0%75.0%
33.33%65.061312,82950.0%25.0%
33.33%61.146511,401100.0%20.0%
83.33%61.25458,39066.7%100.0%
0.00%52.23247,1650.0%0.0%
80.00%50.54628,907100.0%50.0%
60.00%50.93939,10175.0%0.0%
40.00%51.34167,95266.7%0.0%
60.00%52.25469,34450.0%100.0%
20.00%52.562911,2220.0%50.0%
20.00%50.63788,68225.0%0.0%

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Pyke vs Seraphine - Frequently Asked Questions

How does Pyke do against Seraphine in League of Legends?

Seraphine wins the Pyke vs Seraphine matchup with a 51.8% win rate compared to Pyke's 48.3%, a 3.5 percentage point difference. This data is based on 400 recent ranked games in patch 26.10.

How does Pyke do against Seraphine in the early game?

In the early game, Pyke has the advantage against Seraphine with a 50.0% win rate versus 50.0%. Pyke players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Pyke do against Seraphine in the late game?

In the late game, Seraphine takes over the Pyke vs Seraphine matchup with a 52.9% win rate compared to 47.1%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Pyke vs Seraphine matchup?

Seraphine wins the matchup against Pyke with a 51.8% win rate in League of Legends patch 26.10. The 3.5 percentage point advantage means Seraphine is moderately favored in this lane matchup based on 400 games analyzed.

What is the best Pyke build against Seraphine?

The best Pyke build against Seraphine includes Axiom Arc, Serpent's Fang, Edge of Night with Ionian Boots of Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Pyke runes against Seraphine?

The best Pyke runes against Seraphine use the Domination primary tree with Sorcery secondary. This rune setup achieves a 62.5% win rate in the Pyke vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Pyke counter Seraphine?

No, Pyke struggles against Seraphine with only a 48.3% win rate. Seraphine has the advantage in this matchup. Pyke players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.

How do I play Pyke against Seraphine?

When playing Pyke against Seraphine, play cautiously and avoid Seraphine's power spikes. Look for jungle assistance and team-dependent plays since Seraphine has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.