Qiyana - League of Legends Champion
Win Rate
47.5%
Pick Rate
1.1%

Qiyanavs Cassiopeia

FAssassin
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 7, 2026
MethodologyData Methodology

Qiyana vs Cassiopeia is a decisive matchup in LoL patch 26.11. Qiyana wins with a 66.7% win rate (+33.3%) over Cassiopeia based on 6 games. Qiyana holds the advantage in both the early and late game. Below you'll find the best Qiyana build, runes, laning stats, and strategies for the Qiyana vs Cassiopeia matchup.

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Qiyana Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Qiyana performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Qiyana - 66.7% win rate in this matchup
Qiyana
66.7% WR
VS
Cassiopeia vs Qiyana matchup - 33.3% win rate
Cassiopeia
33.3% WR

Who Wins the Qiyana vs Cassiopeia Matchup?

Qiyana wins the Qiyana vs Cassiopeia matchup
Winner
Qiyana
Matches: 6
66.7%
Win Rate
33.3%
5.9
CS / min
6.8
818
DMG / min
635
12,779
Gold / game
10,697
120
Heal / min
164
517
DMG Mitigated / min
552
0.7
CC / min
0.9
50.0%
Early Game WR
50.0%
75.0%
Late Game WR
25.0%

Qiyana vs Cassiopeia Matchup Summary

The Qiyana vs Cassiopeia matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Qiyana wins with a 66.7% win rate compared to Cassiopeia's 33.3%, giving Qiyana a 33.3 percentage point advantage. Qiyana dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Cassiopeia players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Cassiopeia leads by 0.2s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Qiyana players can confidently pick into Cassiopeia and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Cassiopeia away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Qiyana vs Cassiopeia Laning Phase Breakdown

Cassiopeia wins the laning phase against Qiyana in League of Legends

Cassiopeia is favored during the laning phase against Qiyana, winning 3 out of 5 key stat categories. Cassiopeia holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.

Farming
5.9Qiyana
6.8Cassiopeia
Cassiopeia significantly out-farms Qiyana by 0.9 CS per minute, accumulating an estimated 13 CS lead by mid game. This substantial farming gap gives Cassiopeia a major gold advantage and earlier item completions. Qiyana players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
818Qiyana
635Cassiopeia
Qiyana heavily out-damages Cassiopeia by 184 DMG/min, dominating both short trades and all-in fights. Cassiopeia should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Qiyana's sustained damage advantage take over.
Economy
12,779Qiyana
10,697Cassiopeia
Qiyana generates a commanding 2,082 more gold per game than Cassiopeia. This substantial economic advantage means Qiyana consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Cassiopeia should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.7Qiyana
0.9Cassiopeia
Both Qiyana and Cassiopeia provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
638Qiyana
716Cassiopeia
Cassiopeia heals and mitigates 79 more damage per minute than Qiyana, providing moderate extra durability. This sustain edge allows Cassiopeia to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Qiyana.

Best Qiyana Build Against Cassiopeia

Immortal Path is the optimal boots choice against Cassiopeia, providing the mobility and stats Qiyana needs most in this matchup. The top-performing core items for Qiyana against Cassiopeia are Voltaic Cyclosword, Profane Hydra and Serylda's Grudge. This combination gives Qiyana an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Cassiopeia. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Qiyana vs Cassiopeia matchup.

Early Game vs Late Game

Early Game
Qiyana
50.0%
+0.0% advantage
Qiyana early game win rateQiyana50.0%
Cassiopeia early game win rateCassiopeia50.0%
Late Game
Qiyana
75.0%
+50.0% advantage
Qiyana late game win rateQiyana75.0%
Cassiopeia late game win rateCassiopeia25.0%

The early game (first 15 minutes) is a toss-up between Qiyana and Cassiopeia, with Qiyana holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Qiyana is far superior in the late game (25+ minutes), boasting a 75.0% win rate — 50.0 points above Cassiopeia. Extended games heavily favor Qiyana, whose kit and scaling make them a dominant force in team fights and objective control.

Qiyana holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Cassiopeia players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Qiyana Runes Against Cassiopeia

Domination rune tree - Qiyana primary runes vs CassiopeiaDomination
Electrocute - best Qiyana rune vs CassiopeiaSudden Impact - best Qiyana rune vs CassiopeiaGrisly Mementos - best Qiyana rune vs CassiopeiaTreasure Hunter - best Qiyana rune vs Cassiopeia
Precision rune tree - Qiyana secondary runes vs CassiopeiaPrecision
Last Stand - best Qiyana rune vs CassiopeiaPresence of Mind - best Qiyana rune vs Cassiopeia
100.0% WR

Running Domination primary with Precision secondary allows Qiyana to press their advantage against Cassiopeia, amplifying the strengths that make this a favorable matchup.


Qiyana matchup data for League of Legends patch 26.11. The table below shows Qiyana's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Qiyana build, runes, laning stats, and early vs late game analysis for that specific matchup.

Qiyana matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
45.59%686.189311,93955.3%33.3%
54.39%575.786712,37962.5%48.5%
40.00%556.280411,73633.3%45.2%
31.37%515.579611,15333.3%30.0%
38.30%476.281012,19140.9%36.0%
52.27%446.11,03813,41861.1%46.1%
50.00%425.892112,52941.2%56.0%
48.78%415.887911,98041.2%54.2%
28.95%385.076312,48618.8%36.4%
45.71%356.082312,89543.8%47.4%
58.82%344.597913,60560.0%57.9%
41.18%345.179012,37642.9%40.0%
46.88%325.477811,90515.4%68.4%
51.61%315.888413,01258.3%47.4%
55.17%296.299812,56127.3%72.2%
52.00%256.576911,96450.0%54.5%
52.00%254.382214,41650.0%52.9%
48.00%256.392712,84550.0%47.1%
62.50%246.191012,69070.0%57.1%
47.83%234.294511,58246.7%50.0%
34.78%233.874912,83112.5%46.7%
39.13%235.983311,52228.6%55.6%
47.83%231.579114,32666.7%35.7%
36.36%226.180812,04530.8%44.4%
47.62%211.074113,17660.0%36.4%
47.62%211.580013,97050.0%46.1%
52.38%211.874613,48137.5%61.5%
45.00%205.781213,21862.5%33.3%
42.11%195.673011,41712.5%63.6%
57.89%195.697013,23142.9%66.7%
57.89%195.977810,46550.0%71.4%
42.11%196.475711,63520.0%66.7%
42.11%196.080612,07025.0%54.5%
38.89%181.063012,87428.6%45.5%
44.44%181.981312,45636.4%57.1%
61.11%185.778910,23766.7%50.0%
52.94%176.192110,97550.0%57.1%
41.18%176.090713,16340.0%41.7%
52.94%175.998012,19816.7%72.7%
41.18%175.876811,33866.7%27.3%
64.71%171.572613,80350.0%72.7%
43.75%160.884314,54528.6%55.6%
66.67%150.983413,32985.7%50.0%
46.67%155.885610,80250.0%42.9%
60.00%151.880214,05355.6%66.7%
28.57%141.265612,80012.5%50.0%
28.57%144.275510,94333.3%25.0%
61.54%135.574610,68562.5%60.0%
69.23%135.21,01913,50050.0%77.8%
36.36%111.071913,84950.0%20.0%
54.55%110.980712,36333.3%80.0%
36.36%115.895612,96133.3%40.0%
50.00%106.389310,62557.1%33.3%
40.00%101.071714,22675.0%16.7%
40.00%106.582312,84766.7%28.6%
40.00%105.582011,7990.0%66.7%
33.33%96.086611,69033.3%33.3%
22.22%96.07469,42520.0%25.0%
55.56%92.473411,11640.0%75.0%
55.56%96.61,16715,19250.0%60.0%
44.44%94.899213,39550.0%40.0%
11.11%91.583014,7970.0%16.7%
33.33%95.279312,82833.3%33.3%
55.56%91.691414,50325.0%80.0%
50.00%85.979710,07925.0%75.0%
100.00%81.971812,379100.0%100.0%
71.43%72.083412,15175.0%66.7%
57.14%71.757710,03066.7%50.0%
28.57%76.077811,64266.7%0.0%
0.00%70.867413,3340.0%0.0%
71.43%74.61,03116,2480.0%83.3%
57.14%73.371010,23150.0%66.7%
57.14%74.593513,02650.0%60.0%
50.00%62.272112,04333.3%66.7%
66.67%64.91,01915,664100.0%60.0%
33.33%65.71,00412,61025.0%50.0%
50.00%61.380415,962100.0%40.0%
83.33%64.989313,450100.0%75.0%
50.00%60.978111,81333.3%66.7%
66.67%65.981812,77950.0%75.0%
33.33%61.686015,30750.0%25.0%
60.00%56.197315,456100.0%50.0%
60.00%51.171314,986100.0%50.0%
40.00%55.368312,65750.0%33.3%
0.00%55.082411,6730.0%0.0%
60.00%53.41,06814,796100.0%50.0%
60.00%51.193916,141100.0%50.0%
60.00%50.646611,2210.0%100.0%

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Qiyana vs Cassiopeia - Frequently Asked Questions

How does Qiyana do against Cassiopeia in League of Legends?

Qiyana wins the Qiyana vs Cassiopeia matchup with a 66.7% win rate compared to Cassiopeia's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.11.

How does Qiyana do against Cassiopeia in the early game?

In the early game, Qiyana has the advantage against Cassiopeia with a 50.0% win rate versus 50.0%. Qiyana players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Qiyana do against Cassiopeia in the late game?

In the late game, Qiyana takes over the Qiyana vs Cassiopeia matchup with a 75.0% win rate compared to 25.0%. Qiyana scales better into team fights and objective contests after 25 minutes.

Who wins the Qiyana vs Cassiopeia matchup?

Qiyana wins the matchup against Cassiopeia with a 66.7% win rate in League of Legends patch 26.11. The 33.3 percentage point advantage means Qiyana is significantly favored in this lane matchup based on 6 games analyzed.

What is the best Qiyana build against Cassiopeia?

The best Qiyana build against Cassiopeia includes Voltaic Cyclosword, Profane Hydra, Serylda's Grudge with Immortal Path. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Qiyana runes against Cassiopeia?

The best Qiyana runes against Cassiopeia use the Domination primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Qiyana vs Cassiopeia matchup. See the full rune breakdown in the matchup comparison above.

Does Qiyana counter Cassiopeia?

Yes, Qiyana has a favorable matchup against Cassiopeia with a 66.7% win rate. Qiyana strongly counters Cassiopeia in lane based on current patch 26.11 data.

How do I play Qiyana against Cassiopeia?

When playing Qiyana against Cassiopeia, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.