Qiyana - League of Legends Champion
Win Rate
44.8%
Pick Rate
1.6%

Qiyanavs Cassiopeia

FAssassin
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 22, 2026
MethodologyData Methodology

Qiyana vs Cassiopeia is a decisive matchup in LoL patch 26.14. Cassiopeia wins with a 71.4% win rate (+42.9%) over Qiyana based on 7 games. Cassiopeia holds the advantage in both the early and late game. Below you'll find the best Qiyana build, runes, laning stats, and strategies for the Qiyana vs Cassiopeia matchup.

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Qiyana Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Qiyana performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Qiyana - 28.6% win rate in this matchup
Qiyana
28.6% WR
VS
Cassiopeia vs Qiyana matchup - 71.4% win rate
Cassiopeia
71.4% WR

Who Wins the Qiyana vs Cassiopeia Matchup?

Cassiopeia wins the Qiyana vs Cassiopeia matchup
Winner
Cassiopeia
Matches: 7
28.6%
Win Rate
71.4%
5.5
CS / min
6.8
801
DMG / min
910
10,639
Gold / game
11,391
92
Heal / min
239
540
DMG Mitigated / min
548
0.7
CC / min
1.3
25.0%
Early Game WR
75.0%
33.3%
Late Game WR
66.7%

Qiyana vs Cassiopeia Matchup Summary

The Qiyana vs Cassiopeia matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Cassiopeia wins with a 71.4% win rate compared to Qiyana's 28.6%, giving Cassiopeia a 42.9 percentage point advantage. Cassiopeia dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Qiyana players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Cassiopeia leads by 0.6s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Cassiopeia has a strong advantage in this matchup. Qiyana players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Cassiopeia overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Qiyana vs Cassiopeia Laning Phase Breakdown

Cassiopeia wins the laning phase against Qiyana in League of Legends

Cassiopeia is favored during the laning phase against Qiyana, winning 5 out of 5 key stat categories. Cassiopeia holds advantages in farming, damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
5.5Qiyana
6.8Cassiopeia
Cassiopeia significantly out-farms Qiyana by 1.3 CS per minute, accumulating an estimated 19 CS lead by mid game. This substantial farming gap gives Cassiopeia a major gold advantage and earlier item completions. Qiyana players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
801Qiyana
910Cassiopeia
Cassiopeia heavily out-damages Qiyana by 109 DMG/min, dominating both short trades and all-in fights. Qiyana should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Cassiopeia's sustained damage advantage take over.
Economy
10,639Qiyana
11,391Cassiopeia
Cassiopeia earns 752 more gold per game than Qiyana, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Cassiopeia slightly faster item completions.
Utility
0.7Qiyana
1.3Cassiopeia
Cassiopeia provides 0.6 seconds more crowd control per minute than Qiyana, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Cassiopeia coordinate with their jungler and control the pace of skirmishes.
Sustain
632Qiyana
787Cassiopeia
Cassiopeia vastly out-sustains Qiyana, healing and mitigating 155 more damage per minute. This massive durability gap means Cassiopeia can absorb significant punishment and remain in lane while Qiyana is forced to recall. Building grievous wounds early is essential for Qiyana, and focusing on burst trade patterns rather than sustained fights is critical.

Best Qiyana Build Against Cassiopeia

Chainlaced Crushers is the optimal boots choice against Cassiopeia, providing the mobility and stats Qiyana needs most in this matchup. The top-performing core items for Qiyana against Cassiopeia are Voltaic Cyclosword, Profane Hydra and Serylda's Grudge. This combination gives Qiyana an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Cassiopeia. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Qiyana vs Cassiopeia matchup.

Early Game vs Late Game

Early Game
Cassiopeia
75.0%
+50.0% advantage
Qiyana early game win rateQiyana25.0%
Cassiopeia early game win rateCassiopeia75.0%
Late Game
Cassiopeia
66.7%
+33.3% advantage
Qiyana late game win rateQiyana33.3%
Cassiopeia late game win rateCassiopeia66.7%

Cassiopeia dominates the early game (first 15 minutes) with a commanding 75.0% win rate — a 50.0 percentage point lead over Qiyana. This lopsided early game means Cassiopeia can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Cassiopeia is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Qiyana. Extended games heavily favor Cassiopeia, whose kit and scaling make them a dominant force in team fights and objective control.

Cassiopeia holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Qiyana players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Qiyana Runes Against Cassiopeia

Domination rune tree - Qiyana primary runes vs CassiopeiaDomination
Electrocute - best Qiyana rune vs CassiopeiaSudden Impact - best Qiyana rune vs CassiopeiaGrisly Mementos - best Qiyana rune vs CassiopeiaTreasure Hunter - best Qiyana rune vs Cassiopeia
Precision rune tree - Qiyana secondary runes vs CassiopeiaPrecision
Last Stand - best Qiyana rune vs CassiopeiaPresence of Mind - best Qiyana rune vs Cassiopeia
50.0% WR

The Domination and Precision rune setup gives Qiyana the best tools to compete against Cassiopeia in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Qiyana matchup data for League of Legends patch 26.14. The table below shows Qiyana's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Qiyana build, runes, laning stats, and early vs late game analysis for that specific matchup.

Qiyana matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
45.76%594.284212,38338.1%50.0%
56.14%574.991912,54645.8%63.6%
36.73%491.475211,32534.8%38.5%
38.64%445.892412,02835.0%41.7%
53.66%416.390512,01361.1%47.8%
55.00%404.380812,78550.0%57.1%
42.50%403.589513,23741.7%42.9%
50.00%381.265912,83440.0%56.5%
54.05%376.29079,61160.9%42.9%
40.54%370.961511,73033.3%45.5%
58.33%361.275814,07650.0%61.5%
40.00%353.474711,84850.0%33.3%
41.18%345.392710,25457.1%30.0%
35.29%345.988812,66116.7%45.5%
38.24%341.065311,58738.9%37.5%
33.33%336.083111,33133.3%33.3%
35.48%311.066212,61640.0%33.3%
35.71%285.17909,64028.6%42.9%
42.86%281.274113,78155.6%36.8%
40.00%251.077712,01233.3%43.8%
40.91%221.276313,03237.5%42.9%
59.09%226.994911,33553.3%71.4%
45.00%205.777510,05254.5%33.3%
50.00%202.085112,88350.0%50.0%
36.84%195.994913,91766.7%31.3%
38.89%185.06649,84320.0%62.5%
33.33%181.171013,67220.0%38.5%
33.33%181.266713,65583.3%8.3%
35.29%172.567212,30716.7%45.5%
47.06%175.577312,15320.0%58.3%
37.50%165.893111,97242.9%33.3%
56.25%161.273912,64533.3%70.0%
37.50%165.41,05512,97216.7%50.0%
46.67%155.874512,64842.9%50.0%
66.67%151.41,04214,42050.0%72.7%
33.33%150.871612,01928.6%37.5%
50.00%141.180910,86428.6%71.4%
35.71%140.967212,24633.3%37.5%
30.77%131.078211,85225.0%33.3%
30.77%135.972510,82833.3%28.6%
30.77%131.168811,90328.6%33.3%
38.46%130.768711,64140.0%37.5%
50.00%126.173110,88857.1%40.0%
33.33%126.37758,17933.3%33.3%
75.00%123.671410,38966.7%83.3%
45.45%117.098012,36880.0%16.7%
54.55%115.892411,18828.6%100.0%
45.45%111.45549,89550.0%33.3%
50.00%105.880512,61333.3%57.1%
30.00%100.874712,94650.0%16.7%
70.00%102.585510,30050.0%83.3%
40.00%105.389011,7330.0%44.4%
22.22%91.487214,9870.0%25.0%
55.56%95.789413,2600.0%62.5%
55.56%91.079210,16440.0%75.0%
77.78%96.468912,624100.0%71.4%
33.33%90.852810,37940.0%25.0%
33.33%91.591912,14150.0%20.0%
50.00%81.86557,62020.0%100.0%
25.00%80.779811,94050.0%0.0%
12.50%84.77849,2680.0%33.3%
75.00%81.993015,29650.0%100.0%
25.00%84.486911,4940.0%40.0%
71.43%71.270610,65950.0%80.0%
71.43%74.277510,374100.0%50.0%
42.86%71.689511,24033.3%100.0%
42.86%71.176813,03750.0%33.3%
28.57%75.580110,63925.0%33.3%
57.14%75.893213,491100.0%50.0%
28.57%70.963211,43725.0%33.3%
42.86%71.277913,9480.0%50.0%
33.33%61.659312,33233.3%33.3%
50.00%65.15505,98750.0%0.0%
0.00%63.088012,2810.0%0.0%
33.33%62.460912,7700.0%40.0%
50.00%65.89299,53966.7%33.3%
33.33%65.383512,6660.0%50.0%
33.33%62.689910,44150.0%25.0%
40.00%55.18427,92840.0%0.0%
60.00%54.986911,304100.0%50.0%
60.00%55.057911,14233.3%100.0%
0.00%51.074815,2460.0%0.0%
40.00%52.985015,4850.0%40.0%
100.00%55.571713,793100.0%100.0%
20.00%55.98959,0070.0%50.0%
60.00%55.776010,62433.3%100.0%
60.00%53.41,06411,150100.0%33.3%
40.00%55.982014,9770.0%50.0%

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Qiyana vs Cassiopeia - Frequently Asked Questions

How does Qiyana do against Cassiopeia in League of Legends?

Cassiopeia wins the Qiyana vs Cassiopeia matchup with a 71.4% win rate compared to Qiyana's 28.6%, a 42.9 percentage point difference. This data is based on 7 recent ranked games in patch 26.14.

How does Qiyana do against Cassiopeia in the early game?

In the early game, Cassiopeia has the advantage against Qiyana with a 75.0% win rate versus 25.0%. Cassiopeia players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Qiyana do against Cassiopeia in the late game?

In the late game, Cassiopeia takes over the Qiyana vs Cassiopeia matchup with a 66.7% win rate compared to 33.3%. Cassiopeia scales better into team fights and objective contests after 25 minutes.

Who wins the Qiyana vs Cassiopeia matchup?

Cassiopeia wins the matchup against Qiyana with a 71.4% win rate in League of Legends patch 26.14. The 42.9 percentage point advantage means Cassiopeia is significantly favored in this lane matchup based on 7 games analyzed.

What is the best Qiyana build against Cassiopeia?

The best Qiyana build against Cassiopeia includes Voltaic Cyclosword, Profane Hydra, Serylda's Grudge with Chainlaced Crushers. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Qiyana runes against Cassiopeia?

The best Qiyana runes against Cassiopeia use the Domination primary tree with Precision secondary. This rune setup achieves a 50.0% win rate in the Qiyana vs Cassiopeia matchup. See the full rune breakdown in the matchup comparison above.

Does Qiyana counter Cassiopeia?

No, Qiyana struggles against Cassiopeia with only a 28.6% win rate. Cassiopeia has the advantage in this matchup. Qiyana players should focus on safe farming and avoiding extended trades to minimize Cassiopeia's lead.

How do I play Qiyana against Cassiopeia?

When playing Qiyana against Cassiopeia, play cautiously and avoid Cassiopeia's power spikes. Look for jungle assistance and team-dependent plays since Cassiopeia has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.