Qiyana - League of Legends Champion
Win Rate
45.8%
Pick Rate
1.0%

Qiyanavs Cassiopeia

FAssassin
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 22, 2026
MethodologyData Methodology

Qiyana vs Cassiopeia is a decisive matchup in LoL patch 26.7. Cassiopeia wins with a 60.0% win rate (+20.0%) over Qiyana based on 5 games. Qiyana wins the early laning phase while Cassiopeia scales better into the late game. Below you'll find the best Qiyana build, runes, laning stats, and strategies for the Qiyana vs Cassiopeia matchup.

Qiyana Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Qiyana performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Cassiopeia - 40.0% win rateCassiopeia(40.0%)
Qiyana - 40.0% win rate in this matchup
Qiyana
40.0% WR
VS
Cassiopeia vs Qiyana matchup - 60.0% win rate
Cassiopeia
60.0% WR

Who Wins the Qiyana vs Cassiopeia Matchup?

Cassiopeia wins the Qiyana vs Cassiopeia matchup
Winner
Cassiopeia
Matches: 5
40.0%
Win Rate
60.0%
6.2
CS / min
7.1
901
DMG / min
905
14,603
Gold / game
15,491
136
Heal / min
331
551
DMG Mitigated / min
730
0.7
CC / min
1.2
100.0%
Early Game WR
0.0%
25.0%
Late Game WR
75.0%

Qiyana vs Cassiopeia Matchup Summary

The Qiyana vs Cassiopeia matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Cassiopeia wins with a 60.0% win rate compared to Qiyana's 40.0%, giving Cassiopeia a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Qiyana controls the early laning stage, but Cassiopeia outscales as the game goes longer. The matchup shifts dramatically depending on game length — Qiyana needs to press advantages before Cassiopeia reaches their power spikes, while Cassiopeia should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Cassiopeia leads by 0.5s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Cassiopeia has a strong advantage in this matchup. Qiyana players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Cassiopeia overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Qiyana vs Cassiopeia Laning Phase Breakdown

Cassiopeia wins the laning phase against Qiyana in League of Legends

Cassiopeia is favored during the laning phase against Qiyana, winning 5 out of 5 key stat categories. Cassiopeia holds advantages in farming, damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.2Qiyana
7.1Cassiopeia
Cassiopeia significantly out-farms Qiyana by 0.9 CS per minute, accumulating an estimated 14 CS lead by mid game. This substantial farming gap gives Cassiopeia a major gold advantage and earlier item completions. Qiyana players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
901Qiyana
905Cassiopeia
Damage output is virtually even between Qiyana and Cassiopeia, with only 3 DMG/min separating them. Fights in this matchup are decided more by ability timing and positioning than raw damage numbers, making mechanical skill the deciding factor in trades.
Economy
14,603Qiyana
15,491Cassiopeia
Cassiopeia generates a commanding 888 more gold per game than Qiyana. This substantial economic advantage means Cassiopeia consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Qiyana should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.7Qiyana
1.2Cassiopeia
Cassiopeia provides 0.5 seconds more crowd control per minute than Qiyana, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Cassiopeia coordinate with their jungler and control the pace of skirmishes.
Sustain
686Qiyana
1,061Cassiopeia
Cassiopeia vastly out-sustains Qiyana, healing and mitigating 375 more damage per minute. This massive durability gap means Cassiopeia can absorb significant punishment and remain in lane while Qiyana is forced to recall. Building grievous wounds early is essential for Qiyana, and focusing on burst trade patterns rather than sustained fights is critical.

Best Qiyana Build Against Cassiopeia

Mercury's Treads is the optimal boots choice against Cassiopeia, providing the mobility and stats Qiyana needs most in this matchup. The top-performing core items for Qiyana against Cassiopeia are Profane Hydra, Axiom Arc and Serpent's Fang. This combination gives Qiyana an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Cassiopeia. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Qiyana vs Cassiopeia matchup.

Early Game vs Late Game

Early Game
Qiyana
100.0%
+100.0% advantage
Qiyana early game win rateQiyana100.0%
Cassiopeia early game win rateCassiopeia0.0%
Late Game
Cassiopeia
75.0%
+50.0% advantage
Qiyana late game win rateQiyana25.0%
Cassiopeia late game win rateCassiopeia75.0%

Qiyana dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Cassiopeia. This lopsided early game means Qiyana can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Cassiopeia is far superior in the late game (25+ minutes), boasting a 75.0% win rate — 50.0 points above Qiyana. Extended games heavily favor Cassiopeia, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Qiyana must aggressively press their early advantage and close out the game before Cassiopeia reaches their scaling breakpoints. If Cassiopeia survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Qiyana Runes Against Cassiopeia

Precision rune tree - Qiyana primary runes vs CassiopeiaPrecision
Conqueror - best Qiyana rune vs CassiopeiaPresence of Mind - best Qiyana rune vs CassiopeiaLegend: Alacrity - best Qiyana rune vs CassiopeiaCut Down - best Qiyana rune vs Cassiopeia
Domination rune tree - Qiyana secondary runes vs CassiopeiaDomination
Sudden Impact - best Qiyana rune vs CassiopeiaTreasure Hunter - best Qiyana rune vs Cassiopeia
100.0% WR

The Precision and Domination rune setup gives Qiyana the best tools to compete against Cassiopeia in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Qiyana matchup data for League of Legends patch 26.7. The table below shows Qiyana's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Qiyana build, runes, laning stats, and early vs late game analysis for that specific matchup.

Qiyana matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
52.08%486.285012,39343.5%60.0%
42.86%356.487512,53846.7%40.0%
50.00%326.394412,71960.0%41.2%
50.00%306.485212,18350.0%50.0%
51.85%275.983212,46636.4%62.5%
38.46%266.590610,93826.7%54.5%
38.46%266.379110,61037.5%40.0%
60.00%255.796814,23853.3%70.0%
60.87%235.986212,21771.4%56.3%
45.45%226.484811,59866.7%20.0%
63.64%225.31,03012,91870.0%58.3%
45.00%206.082412,23350.0%40.0%
52.63%196.094114,24957.1%50.0%
52.94%176.591513,46962.5%44.4%
35.29%176.683310,92720.0%57.1%
47.06%174.259811,83257.1%40.0%
56.25%166.495913,01557.1%55.6%
37.50%166.589912,60212.5%62.5%
31.25%166.775512,12650.0%12.5%
73.33%156.385912,64875.0%71.4%
46.67%156.377912,28528.6%62.5%
66.67%154.91,05814,89480.0%60.0%
57.14%146.386611,81342.9%71.4%
50.00%145.989111,93966.7%37.5%
38.46%133.772311,68260.0%25.0%
30.77%133.693314,6470.0%40.0%
46.15%131.981614,31933.3%57.1%
66.67%124.892811,69980.0%57.1%
16.67%126.085312,76033.3%0.0%
50.00%125.977912,63425.0%62.5%
63.64%110.964110,48757.1%75.0%
36.36%116.584814,45620.0%50.0%
54.55%116.083910,94250.0%60.0%
40.00%106.391511,77450.0%25.0%
40.00%105.587811,26740.0%40.0%
50.00%106.31,03213,17750.0%50.0%
44.44%95.469312,34650.0%40.0%
44.44%91.274715,5620.0%44.4%
55.56%95.71,03513,20150.0%60.0%
44.44%96.28979,77360.0%25.0%
77.78%96.31,00813,165100.0%66.7%
28.57%76.795415,74750.0%20.0%
57.14%71.797216,36360.0%50.0%
42.86%76.086711,97366.7%25.0%
57.14%71.075414,31850.0%60.0%
33.33%62.264510,98250.0%25.0%
66.67%65.491415,73450.0%75.0%
50.00%61.075912,05333.3%66.7%
50.00%65.579513,6770.0%75.0%
66.67%61.270913,39933.3%100.0%
33.33%61.662012,5370.0%66.7%
33.33%62.692413,0180.0%50.0%
100.00%52.41,07615,530100.0%100.0%
60.00%55.65918,52066.7%50.0%
60.00%50.969412,982100.0%33.3%
20.00%51.459810,8600.0%33.3%
80.00%56.594011,435100.0%50.0%
0.00%51.773814,7350.0%0.0%
40.00%56.290114,603100.0%25.0%

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Qiyana vs Cassiopeia - Frequently Asked Questions

How does Qiyana do against Cassiopeia in League of Legends?

Cassiopeia wins the Qiyana vs Cassiopeia matchup with a 60.0% win rate compared to Qiyana's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.7.

How does Qiyana do against Cassiopeia in the early game?

In the early game, Qiyana has the advantage against Cassiopeia with a 100.0% win rate versus 0.0%. Qiyana players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Qiyana do against Cassiopeia in the late game?

In the late game, Cassiopeia takes over the Qiyana vs Cassiopeia matchup with a 75.0% win rate compared to 25.0%. Cassiopeia scales better into team fights and objective contests after 25 minutes.

Who wins the Qiyana vs Cassiopeia matchup?

Cassiopeia wins the matchup against Qiyana with a 60.0% win rate in League of Legends patch 26.7. The 20.0 percentage point advantage means Cassiopeia is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Qiyana build against Cassiopeia?

The best Qiyana build against Cassiopeia includes Profane Hydra, Axiom Arc, Serpent's Fang with Mercury's Treads. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Qiyana runes against Cassiopeia?

The best Qiyana runes against Cassiopeia use the Precision primary tree with Domination secondary. This rune setup achieves a 100.0% win rate in the Qiyana vs Cassiopeia matchup. See the full rune breakdown in the matchup comparison above.

Does Qiyana counter Cassiopeia?

No, Qiyana struggles against Cassiopeia with only a 40.0% win rate. Cassiopeia has the advantage in this matchup. Qiyana players should focus on safe farming and avoiding extended trades to minimize Cassiopeia's lead.

How do I play Qiyana against Cassiopeia?

When playing Qiyana against Cassiopeia, play cautiously and avoid Cassiopeia's power spikes. Look for jungle assistance and team-dependent plays since Cassiopeia has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.