Cassiopeia - League of Legends Champion
Win Rate
50.4%
Pick Rate
0.8%

Cassiopeiavs Qiyana

BMage
Patch26.10
Matches3,013,751
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 27, 2026
MethodologyData Methodology

Cassiopeia vs Qiyana is a decisive matchup in LoL patch 26.10. Cassiopeia wins with a 55.6% win rate (+11.1%) over Qiyana based on 9 games. Cassiopeia wins the early laning phase while Qiyana scales better into the late game. Below you'll find the best Cassiopeia build, runes, laning stats, and strategies for the Cassiopeia vs Qiyana matchup.

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Cassiopeia Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Cassiopeia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Cassiopeia - 55.6% win rate in this matchup
Cassiopeia
55.6% WR
VS
Qiyana vs Cassiopeia matchup - 44.4% win rate
Qiyana
44.4% WR

Who Wins the Cassiopeia vs Qiyana Matchup?

Cassiopeia wins the Cassiopeia vs Qiyana matchup
Winner
Cassiopeia
Matches: 9
55.6%
Win Rate
44.4%
6.7
CS / min
6.0
791
DMG / min
891
11,106
Gold / game
11,724
262
Heal / min
129
509
DMG Mitigated / min
494
1.1
CC / min
0.8
66.7%
Early Game WR
33.3%
33.3%
Late Game WR
66.7%

Cassiopeia vs Qiyana Matchup Summary

The Cassiopeia vs Qiyana matchup is a decisive matchup in League of Legends ranked play. Based on 9 recent matches analyzed, Cassiopeia wins with a 55.6% win rate compared to Qiyana's 44.4%, giving Cassiopeia a 11.1 percentage point advantage. Game phase dynamics play a critical role here: Cassiopeia controls the early laning stage, but Qiyana outscales as the game goes longer. The matchup shifts dramatically depending on game length — Cassiopeia needs to press advantages before Qiyana reaches their power spikes, while Qiyana should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Cassiopeia leads by 0.4s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Cassiopeia players can confidently pick into Qiyana and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Qiyana away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Cassiopeia vs Qiyana Laning Phase Breakdown

Cassiopeia wins the laning phase against Qiyana in League of Legends

Cassiopeia is favored during the laning phase against Qiyana, winning 3 out of 5 key stat categories. Cassiopeia holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.7Cassiopeia
6.0Qiyana
Cassiopeia edges out Qiyana by 0.7 CS per minute — a moderate farming advantage that adds up to roughly 11 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Cassiopeia.
Damage
791Cassiopeia
891Qiyana
Qiyana heavily out-damages Cassiopeia by 100 DMG/min, dominating both short trades and all-in fights. Cassiopeia should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Qiyana's sustained damage advantage take over.
Economy
11,106Cassiopeia
11,724Qiyana
Qiyana earns 618 more gold per game than Cassiopeia, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Qiyana slightly faster item completions.
Utility
1.1Cassiopeia
0.8Qiyana
Cassiopeia provides 0.4 seconds more crowd control per minute than Qiyana, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Cassiopeia coordinate with their jungler and control the pace of skirmishes.
Sustain
771Cassiopeia
623Qiyana
Cassiopeia heals and mitigates 148 more damage per minute than Qiyana, providing moderate extra durability. This sustain edge allows Cassiopeia to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Qiyana.

Best Cassiopeia Build Against Qiyana

Spellslinger's Shoes is the optimal boots choice against Qiyana, providing the mobility and stats Cassiopeia needs most in this matchup. The top-performing core items for Cassiopeia against Qiyana are Bloodletter's Curse, Liandry's Torment and Rylai's Crystal Scepter. This combination gives Cassiopeia an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Qiyana. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Cassiopeia vs Qiyana matchup.

Early Game vs Late Game

Early Game
Cassiopeia
66.7%
+33.3% advantage
Cassiopeia early game win rateCassiopeia66.7%
Qiyana early game win rateQiyana33.3%
Late Game
Qiyana
66.7%
+33.3% advantage
Cassiopeia late game win rateCassiopeia33.3%
Qiyana late game win rateQiyana66.7%

Cassiopeia dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Qiyana. This lopsided early game means Cassiopeia can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Qiyana is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Cassiopeia. Extended games heavily favor Qiyana, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Cassiopeia must aggressively press their early advantage and close out the game before Qiyana reaches their scaling breakpoints. If Qiyana survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Cassiopeia Runes Against Qiyana

Sorcery rune tree - Cassiopeia primary runes vs QiyanaSorcery
Deathfire Touch - best Cassiopeia rune vs QiyanaManaflow Band - best Cassiopeia rune vs QiyanaCelerity - best Cassiopeia rune vs QiyanaScorch - best Cassiopeia rune vs Qiyana
Resolve rune tree - Cassiopeia secondary runes vs QiyanaResolve
Bone Plating - best Cassiopeia rune vs QiyanaOvergrowth - best Cassiopeia rune vs Qiyana
100.0% WR

Running Sorcery primary with Resolve secondary allows Cassiopeia to press their advantage against Qiyana, amplifying the strengths that make this a favorable matchup.


Cassiopeia matchup data for League of Legends patch 26.10. The table below shows Cassiopeia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Cassiopeia build, runes, laning stats, and early vs late game analysis for that specific matchup.

Cassiopeia matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
52.73%556.276811,05542.3%62.1%
60.38%536.989011,48859.1%61.3%
42.55%476.577111,91145.0%40.7%
56.52%466.692610,96450.0%63.6%
53.85%396.783212,36066.7%45.8%
42.11%386.61,00911,33238.9%45.0%
51.35%376.475611,13143.8%57.1%
48.57%356.580011,75540.0%55.0%
57.14%356.181310,96050.0%61.9%
45.45%336.775511,80750.0%41.2%
43.75%327.093210,88631.8%70.0%
29.03%316.582611,31635.3%21.4%
51.61%316.075511,44347.1%57.1%
60.00%306.986112,22975.0%50.0%
43.33%306.076012,12337.5%45.5%
63.33%306.672411,56953.3%73.3%
65.52%296.392912,32860.0%71.4%
42.86%286.289211,98133.3%47.4%
46.15%266.675211,20557.1%33.3%
60.00%256.796313,39540.0%73.3%
54.17%246.598212,38571.4%47.1%
33.33%245.887711,20842.9%29.4%
59.09%226.887012,15062.5%57.1%
63.64%225.993011,11740.0%83.3%
57.14%217.21,01411,55450.0%66.7%
33.33%216.392913,16125.0%38.5%
57.14%216.378311,05941.7%77.8%
55.00%206.184511,82333.3%64.3%
45.00%206.484911,36350.0%41.7%
45.00%207.286610,03450.0%37.5%
42.11%196.685612,70045.5%37.5%
63.16%196.874010,51370.0%55.6%
42.11%197.081010,63863.6%12.5%
63.16%196.985212,97987.5%45.5%
64.71%176.583212,19440.0%75.0%
35.29%176.389313,64066.7%18.2%
43.75%166.476110,71850.0%37.5%
43.75%166.776011,81660.0%36.4%
50.00%166.21,00610,35240.0%66.7%
75.00%165.880211,25775.0%75.0%
46.67%156.897711,98944.4%50.0%
35.71%146.382012,11860.0%22.2%
21.43%147.11,02712,32333.3%12.5%
69.23%136.09168,49783.3%57.1%
58.33%125.792511,67260.0%57.1%
54.55%115.473912,561100.0%16.7%
72.73%116.71,00515,21875.0%71.4%
72.73%115.868012,86666.7%75.0%
60.00%106.397212,14366.7%50.0%
30.00%106.770610,00020.0%40.0%
50.00%106.77999,73442.9%66.7%
50.00%106.37188,75350.0%50.0%
60.00%106.887310,53671.4%33.3%
40.00%106.31,09912,73225.0%50.0%
50.00%107.797414,27550.0%50.0%
44.44%97.086312,43833.3%66.7%
55.56%96.779111,10666.7%33.3%
55.56%96.18339,52966.7%50.0%
55.56%96.31,11813,42233.3%66.7%
33.33%96.294912,10950.0%28.6%
62.50%86.779910,60175.0%50.0%
37.50%86.276511,12625.0%50.0%
25.00%87.07339,68920.0%33.3%
37.50%86.988112,58850.0%25.0%
87.50%87.61,18713,48075.0%100.0%
57.14%76.784413,78933.3%75.0%
71.43%76.31,03714,30550.0%80.0%
71.43%76.797013,10666.7%75.0%
14.29%76.789411,7940.0%25.0%
71.43%75.21,01012,81666.7%75.0%
42.86%75.467712,368100.0%20.0%
71.43%77.485912,46850.0%100.0%
28.57%76.792711,9660.0%66.7%
57.14%75.982111,44666.7%50.0%
16.67%66.691310,53950.0%0.0%
66.67%66.194815,2610.0%100.0%
33.33%67.29659,13725.0%50.0%
66.67%66.098612,63260.0%100.0%
50.00%65.578312,4100.0%75.0%
33.33%66.277010,5720.0%66.7%
60.00%56.996317,030100.0%33.3%
20.00%56.871311,2030.0%50.0%
40.00%54.968610,24433.3%50.0%
60.00%56.199212,924100.0%50.0%
40.00%56.91,09512,86050.0%33.3%
20.00%55.192111,56350.0%0.0%
60.00%57.576611,21750.0%66.7%
60.00%54.991811,83750.0%66.7%
80.00%57.075012,94666.7%100.0%

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Cassiopeia vs Qiyana - Frequently Asked Questions

How does Cassiopeia do against Qiyana in League of Legends?

Cassiopeia wins the Cassiopeia vs Qiyana matchup with a 55.6% win rate compared to Qiyana's 44.4%, a 11.1 percentage point difference. This data is based on 9 recent ranked games in patch 26.10.

How does Cassiopeia do against Qiyana in the early game?

In the early game, Cassiopeia has the advantage against Qiyana with a 66.7% win rate versus 33.3%. Cassiopeia players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Cassiopeia do against Qiyana in the late game?

In the late game, Qiyana takes over the Cassiopeia vs Qiyana matchup with a 66.7% win rate compared to 33.3%. Qiyana scales better into team fights and objective contests after 25 minutes.

Who wins the Cassiopeia vs Qiyana matchup?

Cassiopeia wins the matchup against Qiyana with a 55.6% win rate in League of Legends patch 26.10. The 11.1 percentage point advantage means Cassiopeia is significantly favored in this lane matchup based on 9 games analyzed.

What is the best Cassiopeia build against Qiyana?

The best Cassiopeia build against Qiyana includes Bloodletter's Curse, Liandry's Torment, Rylai's Crystal Scepter with Spellslinger's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Cassiopeia runes against Qiyana?

The best Cassiopeia runes against Qiyana use the Sorcery primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Cassiopeia vs Qiyana matchup. See the full rune breakdown in the matchup comparison above.

Does Cassiopeia counter Qiyana?

Yes, Cassiopeia has a favorable matchup against Qiyana with a 55.6% win rate. Cassiopeia strongly counters Qiyana in lane based on current patch 26.10 data.

How do I play Cassiopeia against Qiyana?

When playing Cassiopeia against Qiyana, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.