Qiyana - League of Legends Champion
Win Rate
47.2%
Pick Rate
1.2%

Qiyanavs Kai'Sa

FAssassin
Patch26.9
Matches514,344
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 9, 2026
MethodologyData Methodology

Qiyana vs Kai'Sa is a decisive matchup in LoL patch 26.9. Qiyana wins with a 80.0% win rate (+60.0%) over Kai'Sa based on 5 games. Qiyana holds the advantage in both the early and late game. Below you'll find the best Qiyana build, runes, laning stats, and strategies for the Qiyana vs Kai'Sa matchup.

Qiyana Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Qiyana performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Kai'Sa - 80.0% win rateKai'Sa(80.0%)
Qiyana - 80.0% win rate in this matchup
Qiyana
80.0% WR
VS
Kai'Sa vs Qiyana matchup - 20.0% win rate
Kai'Sa
20.0% WR

Who Wins the Qiyana vs Kai'Sa Matchup?

Qiyana wins the Qiyana vs Kai'Sa matchup
Winner
Qiyana
Matches: 5
80.0%
Win Rate
20.0%
5.1
CS / min
5.4
772
DMG / min
607
11,535
Gold / game
9,900
233
Heal / min
175
433
DMG Mitigated / min
470
0.6
CC / min
0.1
66.7%
Early Game WR
33.3%
100.0%
Late Game WR
0.0%

Qiyana vs Kai'Sa Matchup Summary

The Qiyana vs Kai'Sa matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Qiyana wins with a 80.0% win rate compared to Kai'Sa's 20.0%, giving Qiyana a 60.0 percentage point advantage. Qiyana dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Kai'Sa players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Qiyana leads by 0.5s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Qiyana players can confidently pick into Kai'Sa and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Kai'Sa away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Qiyana vs Kai'Sa Laning Phase Breakdown

Qiyana wins the laning phase against Kai'Sa in League of Legends

Qiyana is favored during the laning phase against Kai'Sa, winning 4 out of 5 key stat categories. Qiyana holds advantages in damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
5.1Qiyana
5.4Kai'Sa
Kai'Sa edges out Qiyana by 0.3 CS per minute — a moderate farming advantage that adds up to roughly 5 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Kai'Sa.
Damage
772Qiyana
607Kai'Sa
Qiyana heavily out-damages Kai'Sa by 165 DMG/min, dominating both short trades and all-in fights. Kai'Sa should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Qiyana's sustained damage advantage take over.
Economy
11,535Qiyana
9,900Kai'Sa
Qiyana generates a commanding 1,634 more gold per game than Kai'Sa. This substantial economic advantage means Qiyana consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Kai'Sa should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.6Qiyana
0.1Kai'Sa
Qiyana provides 0.5 seconds more crowd control per minute than Kai'Sa, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Qiyana coordinate with their jungler and control the pace of skirmishes.
Sustain
666Qiyana
645Kai'Sa
Qiyana and Kai'Sa have comparable sustain profiles, with only 21 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Best Qiyana Build Against Kai'Sa

Ionian Boots of Lucidity is the optimal boots choice against Kai'Sa, providing the mobility and stats Qiyana needs most in this matchup. The top-performing core items for Qiyana against Kai'Sa are Voltaic Cyclosword, Profane Hydra and Hubris. This combination gives Qiyana an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Qiyana vs Kai'Sa matchup.

Early Game vs Late Game

Early Game
Qiyana
66.7%
+33.3% advantage
Qiyana early game win rateQiyana66.7%
Kai'Sa early game win rateKai'Sa33.3%
Late Game
Qiyana
100.0%
+100.0% advantage
Qiyana late game win rateQiyana100.0%
Kai'Sa late game win rateKai'Sa0.0%

Qiyana dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Kai'Sa. This lopsided early game means Qiyana can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Qiyana is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Kai'Sa. Extended games heavily favor Qiyana, whose kit and scaling make them a dominant force in team fights and objective control.

Qiyana holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Kai'Sa players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Qiyana Runes Against Kai'Sa

Domination rune tree - Qiyana primary runes vs Kai'SaDomination
Electrocute - best Qiyana rune vs Kai'SaSudden Impact - best Qiyana rune vs Kai'SaSixth Sense - best Qiyana rune vs Kai'SaRelentless Hunter - best Qiyana rune vs Kai'Sa
Precision rune tree - Qiyana secondary runes vs Kai'SaPrecision
Presence of Mind - best Qiyana rune vs Kai'SaCut Down - best Qiyana rune vs Kai'Sa
100.0% WR

Running Domination primary with Precision secondary allows Qiyana to press their advantage against Kai'Sa, amplifying the strengths that make this a favorable matchup.


Qiyana matchup data for League of Legends patch 26.9. The table below shows Qiyana's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Qiyana build, runes, laning stats, and early vs late game analysis for that specific matchup.

Qiyana matchup win rates and stats in League of Legends patch 26.9
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
53.33%456.379911,74756.0%50.0%
37.21%436.276612,07344.4%32.0%
48.78%416.187711,85662.5%40.0%
45.00%406.185212,62052.9%39.1%
62.16%376.690013,54761.5%62.5%
48.57%356.688111,45945.5%53.9%
35.29%344.074110,62222.7%58.3%
50.00%326.075511,37642.9%55.6%
56.25%326.272710,95764.3%50.0%
51.85%276.391312,52364.3%38.5%
51.85%276.591011,96937.5%72.7%
50.00%265.971510,00440.0%63.6%
38.46%265.584111,13929.4%55.6%
45.83%244.686511,99642.9%50.0%
59.09%226.079412,30166.7%53.9%
45.45%226.489712,60733.3%53.9%
38.10%214.264710,62941.7%33.3%
52.38%216.284012,48842.9%57.1%
42.86%211.174412,95540.0%45.5%
31.58%195.971710,70833.3%28.6%
31.58%191.169312,64320.0%44.4%
33.33%186.085712,01330.0%37.5%
61.11%185.91,10012,45160.0%62.5%
58.82%175.892412,15363.6%50.0%
58.82%175.994212,14962.5%55.6%
56.25%166.89259,84272.7%20.0%
37.50%161.274813,74680.0%18.2%
62.50%166.192412,72566.7%60.0%
43.75%166.378411,64340.0%50.0%
25.00%166.067911,36233.3%20.0%
43.75%166.71,03412,14660.0%16.7%
50.00%146.294312,50544.4%60.0%
42.86%146.277512,60980.0%22.2%
57.14%141.480514,32533.3%75.0%
64.29%146.798112,48962.5%66.7%
30.77%134.874311,51728.6%33.3%
61.54%132.11,01813,30066.7%57.1%
38.46%136.081212,67933.3%42.9%
23.08%131.070112,71233.3%14.3%
53.85%135.877711,48057.1%50.0%
16.67%126.572111,0800.0%28.6%
25.00%126.074110,9310.0%37.5%
45.45%111.360410,86437.5%66.7%
70.00%101.394917,314100.0%66.7%
60.00%101.187215,45450.0%62.5%
50.00%106.01,07514,77366.7%42.9%
70.00%102.587413,05575.0%66.7%
33.33%92.474412,42860.0%0.0%
77.78%96.31,01112,18960.0%100.0%
66.67%95.995112,11775.0%60.0%
33.33%95.272013,15950.0%28.6%
22.22%90.980314,4010.0%33.3%
55.56%90.975215,45250.0%60.0%
44.44%92.898611,07725.0%60.0%
37.50%81.172614,78850.0%33.3%
75.00%86.51,31015,06360.0%100.0%
37.50%86.891412,78133.3%40.0%
25.00%85.370412,0580.0%50.0%
37.50%80.784110,74840.0%33.3%
71.43%72.566913,88280.0%50.0%
71.43%71.472112,33475.0%66.7%
71.43%73.079412,5650.0%100.0%
71.43%71.388612,56780.0%50.0%
28.57%71.172813,51250.0%20.0%
57.14%73.777911,9120.0%100.0%
33.33%66.31,05912,9900.0%50.0%
33.33%61.290015,90625.0%50.0%
50.00%60.760312,25866.7%33.3%
66.67%67.41,21415,143100.0%33.3%
50.00%65.71,06814,06150.0%50.0%
83.33%61.284013,79850.0%100.0%
20.00%51.270614,9820.0%20.0%
40.00%51.193115,946100.0%25.0%
0.00%52.96659,7450.0%0.0%
60.00%50.979210,16966.7%50.0%
20.00%53.966010,30550.0%0.0%
20.00%52.288011,9860.0%100.0%
20.00%50.89969,9510.0%50.0%
80.00%55.177211,53566.7%100.0%

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Qiyana vs Kai'Sa - Frequently Asked Questions

How does Qiyana do against Kai'Sa in League of Legends?

Qiyana wins the Qiyana vs Kai'Sa matchup with a 80.0% win rate compared to Kai'Sa's 20.0%, a 60.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.9.

How does Qiyana do against Kai'Sa in the early game?

In the early game, Qiyana has the advantage against Kai'Sa with a 66.7% win rate versus 33.3%. Qiyana players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Qiyana do against Kai'Sa in the late game?

In the late game, Qiyana takes over the Qiyana vs Kai'Sa matchup with a 100.0% win rate compared to 0.0%. Qiyana scales better into team fights and objective contests after 25 minutes.

Who wins the Qiyana vs Kai'Sa matchup?

Qiyana wins the matchup against Kai'Sa with a 80.0% win rate in League of Legends patch 26.9. The 60.0 percentage point advantage means Qiyana is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Qiyana build against Kai'Sa?

The best Qiyana build against Kai'Sa includes Voltaic Cyclosword, Profane Hydra, Hubris with Ionian Boots of Lucidity. Check the matchup breakdown above for the full item path and build order.

What are the best Qiyana runes against Kai'Sa?

The best Qiyana runes against Kai'Sa use the Domination primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Qiyana vs Kai'Sa matchup. See the full rune breakdown in the matchup comparison above.

Does Qiyana counter Kai'Sa?

Yes, Qiyana has a favorable matchup against Kai'Sa with a 80.0% win rate. Qiyana strongly counters Kai'Sa in lane based on current patch 26.9 data.

How do I play Qiyana against Kai'Sa?

When playing Qiyana against Kai'Sa, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.