
Samiravs Vayne
Samira vs Vayne is a very close matchup in LoL patch 26.10. Samira wins with a 50.8% win rate (+1.6%) over Vayne based on 189 games. Samira holds the advantage in both the early and late game. Below you'll find the best Samira build, runes, laning stats, and strategies for the Samira vs Vayne matchup.
Samira Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Samira performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Samira vs Vayne Matchup?

Samira vs Vayne Matchup Summary
The Samira vs Vayne matchup is a very close matchup in League of Legends ranked play. Based on 189 recent matches analyzed, Samira wins with a 50.8% win rate compared to Vayne's 49.2%, giving Samira a 1.6 percentage point advantage. Samira holds a slight edge in both the early and late game, but the margins are thin enough that individual skill and jungle attention will often determine the outcome. Vayne can still find windows through outplays and team coordination. The most significant statistical gap is in crowd control, where Vayne leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Samira has a statistical edge, but the margin is close enough that respecting Vayne's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Samira vs Vayne Laning Phase Breakdown
Samira is favored during the laning phase against Vayne, winning 4 out of 5 key stat categories. Samira holds advantages in farming, damage, gold income and sustain, making them the stronger laner in this matchup.
Best Samira Build Against Vayne
Immortal Path is the optimal boots choice against Vayne, providing the mobility and stats Samira needs most in this matchup. The top-performing core items for Samira against Vayne are The Collector, Lord Dominik's Regards and Infinity Edge. This combination gives Samira an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Samira vs Vayne matchup.
Early Game vs Late Game
During the early laning phase (first 15 minutes), Samira has a meaningful 51.6% win rate, outperforming Vayne by 3.2 percentage points. Samira players should look to press this advantage through aggressive trades, wave priority, and early jungle coordination.
Late game (25+ minutes) is equally balanced, with Samira at 50.0% win rate — only 0.0 points ahead of Vayne. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.
Samira holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Samira Runes Against Vayne
The Precision primary with Domination secondary combination helps Samira maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Vayne.
Samira matchup data for League of Legends patch 26.10. The table below shows Samira's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Samira build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 45.66% | 692 | 6.5 | 937 | 14,105 | 50.3% | 42.1% | |
| 49.57% | 468 | 6.3 | 858 | 13,562 | 49.5% | 49.6% | |
| 43.85% | 447 | 6.4 | 853 | 13,666 | 42.1% | 45.6% | |
| 49.39% | 409 | 6.1 | 863 | 13,542 | 48.3% | 50.2% | |
| 42.30% | 383 | 6.4 | 861 | 13,309 | 42.3% | 42.3% | |
| 49.53% | 317 | 6.3 | 919 | 14,225 | 45.9% | 52.6% | |
| 48.89% | 270 | 6.3 | 879 | 13,896 | 43.2% | 54.4% | |
| 52.66% | 207 | 6.5 | 970 | 14,689 | 49.4% | 55.1% | |
| 50.79% | 189 | 6.4 | 994 | 14,683 | 51.6% | 50.0% | |
| 49.10% | 167 | 6.3 | 909 | 13,859 | 45.2% | 53.0% | |
| 54.01% | 137 | 6.3 | 822 | 13,622 | 53.5% | 54.5% | |
| 49.60% | 125 | 6.2 | 899 | 13,896 | 45.2% | 54.0% | |
| 38.60% | 114 | 6.2 | 780 | 12,772 | 38.3% | 38.9% | |
| 38.68% | 106 | 6.5 | 823 | 13,181 | 39.3% | 38.0% | |
| 55.10% | 98 | 6.6 | 963 | 15,153 | 64.3% | 48.2% | |
| 48.39% | 93 | 6.6 | 943 | 14,556 | 47.8% | 48.9% | |
| 50.57% | 87 | 6.5 | 926 | 13,578 | 42.9% | 60.5% | |
| 50.00% | 86 | 6.4 | 939 | 14,309 | 46.0% | 53.1% | |
| 60.26% | 78 | 6.3 | 917 | 14,659 | 51.7% | 65.3% | |
| 44.87% | 78 | 6.2 | 865 | 13,187 | 44.4% | 45.2% | |
| 47.06% | 68 | 6.4 | 864 | 12,830 | 46.1% | 48.3% | |
| 56.67% | 60 | 6.3 | 881 | 14,105 | 51.4% | 64.0% | |
| 41.82% | 55 | 6.2 | 906 | 13,449 | 48.1% | 35.7% | |
| 59.26% | 54 | 6.7 | 882 | 12,887 | 56.3% | 63.6% | |
| 52.27% | 44 | 6.4 | 846 | 13,523 | 45.0% | 58.3% | |
| 44.19% | 43 | 6.1 | 901 | 13,055 | 38.1% | 50.0% | |
| 53.85% | 39 | 6.3 | 973 | 13,304 | 50.0% | 57.1% | |
| 41.94% | 31 | 6.1 | 857 | 14,725 | 43.8% | 40.0% | |
| 56.67% | 30 | 6.5 | 1,011 | 13,731 | 43.8% | 71.4% | |
| 44.83% | 29 | 6.3 | 791 | 13,511 | 50.0% | 38.5% | |
| 36.00% | 25 | 6.0 | 882 | 14,170 | 33.3% | 37.5% | |
| 30.43% | 23 | 6.4 | 713 | 12,818 | 33.3% | 27.3% | |
| 28.57% | 21 | 6.5 | 745 | 13,737 | 25.0% | 30.8% | |
| 52.63% | 19 | 6.3 | 787 | 13,261 | 57.1% | 50.0% | |
| 46.67% | 15 | 6.6 | 845 | 15,036 | 33.3% | 55.6% | |
| 53.33% | 15 | 6.4 | 888 | 14,428 | 20.0% | 70.0% | |
| 35.71% | 14 | 5.8 | 1,068 | 14,020 | 33.3% | 37.5% | |
| 58.33% | 12 | 6.5 | 857 | 13,308 | 16.7% | 100.0% | |
| 45.45% | 11 | 6.7 | 1,070 | 10,679 | 57.1% | 25.0% | |
| 45.45% | 11 | 6.9 | 1,139 | 17,209 | 75.0% | 28.6% | |
| 44.44% | 9 | 5.9 | 828 | 14,051 | 50.0% | 40.0% | |
| 50.00% | 8 | 6.1 | 972 | 15,592 | 50.0% | 50.0% | |
| 50.00% | 8 | 6.3 | 799 | 12,223 | 66.7% | 0.0% | |
| 12.50% | 8 | 5.8 | 801 | 14,207 | 0.0% | 16.7% | |
| 62.50% | 8 | 6.7 | 650 | 12,059 | 60.0% | 66.7% | |
| 42.86% | 7 | 6.5 | 691 | 10,613 | 50.0% | 0.0% | |
| 57.14% | 7 | 6.3 | 732 | 15,585 | 0.0% | 66.7% | |
| 50.00% | 6 | 4.3 | 555 | 9,910 | 25.0% | 100.0% | |
| 33.33% | 6 | 5.7 | 827 | 11,476 | 50.0% | 25.0% | |
| 80.00% | 5 | 5.7 | 762 | 13,693 | 66.7% | 100.0% | |
| 0.00% | 5 | 6.5 | 629 | 8,613 | 0.0% | 0.0% | |
| 20.00% | 5 | 5.6 | 556 | 11,300 | 33.3% | 0.0% | |
| 20.00% | 5 | 6.4 | 776 | 11,214 | 0.0% | 100.0% | |
| 40.00% | 5 | 6.2 | 1,048 | 13,763 | 0.0% | 100.0% | |
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Samira vs Vayne - Frequently Asked Questions
How does Samira do against Vayne in League of Legends?
Samira wins the Samira vs Vayne matchup with a 50.8% win rate compared to Vayne's 49.2%, a 1.6 percentage point difference. This data is based on 189 recent ranked games in patch 26.10.
How does Samira do against Vayne in the early game?
In the early game, Samira has the advantage against Vayne with a 51.6% win rate versus 48.4%. Samira players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Samira do against Vayne in the late game?
In the late game, Samira takes over the Samira vs Vayne matchup with a 50.0% win rate compared to 50.0%. Samira scales better into team fights and objective contests after 25 minutes.
Who wins the Samira vs Vayne matchup?
Samira wins the matchup against Vayne with a 50.8% win rate in League of Legends patch 26.10. The 1.6 percentage point advantage means Samira is slightly favored in this lane matchup based on 189 games analyzed.
What is the best Samira build against Vayne?
The best Samira build against Vayne includes The Collector, Lord Dominik's Regards, Infinity Edge with Immortal Path. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Samira runes against Vayne?
The best Samira runes against Vayne use the Precision primary tree with Domination secondary. This rune setup achieves a 49.0% win rate in the Samira vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Samira counter Vayne?
Yes, Samira has a favorable matchup against Vayne with a 50.8% win rate. Samira slightly edges out Vayne in lane based on current patch 26.10 data.
How do I play Samira against Vayne?
When playing Samira against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.
