Samira - League of Legends Champion
Win Rate
47.9%
Pick Rate
2.7%

Samiravs Vayne

FMarksmanAssassin
Patch26.7
Matches508,082
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 14, 2026
MethodologyData Methodology

Samira vs Vayne is a moderate matchup in LoL patch 26.7. Samira wins with a 52.3% win rate (+4.6%) over Vayne based on 109 games. Samira wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Samira build, runes, laning stats, and strategies for the Samira vs Vayne matchup.

Samira Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Samira performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 52.3% win rateVayne(52.3%)
Samira - 52.3% win rate in this matchup
Samira
52.3% WR
VS
Vayne vs Samira matchup - 47.7% win rate
Vayne
47.7% WR

Who Wins the Samira vs Vayne Matchup?

Samira wins the Samira vs Vayne matchup
Winner
Samira
Matches: 109
52.3%
Win Rate
47.7%
6.4
CS / min
6.0
932
DMG / min
882
14,220
Gold / game
13,239
266
Heal / min
208
582
DMG Mitigated / min
458
0.1
CC / min
0.4
61.8%
Early Game WR
38.2%
42.6%
Late Game WR
57.4%

Samira vs Vayne Matchup Summary

The Samira vs Vayne matchup is a moderate matchup in League of Legends ranked play. Based on 109 recent matches analyzed, Samira wins with a 52.3% win rate compared to Vayne's 47.7%, giving Samira a 4.6 percentage point advantage. Game phase dynamics play a critical role here: Samira controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Samira needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Vayne leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Samira has a statistical edge, but the margin is close enough that respecting Vayne's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Samira vs Vayne Laning Phase Breakdown

Samira wins the laning phase against Vayne in League of Legends

Samira is favored during the laning phase against Vayne, winning 4 out of 5 key stat categories. Samira holds advantages in farming, damage, gold income and sustain, making them the stronger laner in this matchup.

Farming
6.4Samira
6.0Vayne
Samira edges out Vayne by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 6 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Samira.
Damage
932Samira
882Vayne
Samira deals 51 more champion damage per minute than Vayne. While noticeable in extended trades, this gap can be offset by Vayne choosing favorable fight windows, such as engaging when Samira's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
14,220Samira
13,239Vayne
Samira generates a commanding 982 more gold per game than Vayne. This substantial economic advantage means Samira consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Vayne should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.1Samira
0.4Vayne
Both Samira and Vayne provide similar amounts of crowd control (0.3s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
848Samira
666Vayne
Samira vastly out-sustains Vayne, healing and mitigating 182 more damage per minute. This massive durability gap means Samira can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Early Game vs Late Game

Early Game
Samira
61.8%
+23.6% advantage
Samira early game win rateSamira61.8%
Vayne early game win rateVayne38.2%
Late Game
Vayne
57.4%
+14.8% advantage
Samira late game win rateSamira42.6%
Vayne late game win rateVayne57.4%

Samira dominates the early game (first 15 minutes) with a commanding 61.8% win rate — a 23.6 percentage point lead over Vayne. This lopsided early game means Samira can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Vayne is far superior in the late game (25+ minutes), boasting a 57.4% win rate — 14.8 points above Samira. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Samira must aggressively press their early advantage and close out the game before Vayne reaches their scaling breakpoints. If Vayne survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Samira Runes Against Vayne

Precision rune tree - Samira primary runes vs VaynePrecision
Conqueror - best Samira rune vs VayneTriumph - best Samira rune vs VayneLegend: Bloodline - best Samira rune vs VayneLast Stand - best Samira rune vs Vayne
Resolve rune tree - Samira secondary runes vs VayneResolve
Bone Plating - best Samira rune vs VayneRevitalize - best Samira rune vs Vayne
63.6% WR

Running Precision primary with Resolve secondary allows Samira to press their advantage against Vayne, amplifying the strengths that make this a favorable matchup.


Samira matchup data for League of Legends patch 26.7. The table below shows Samira's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Samira build, runes, laning stats, and early vs late game analysis for that specific matchup.

Samira matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
48.80%2506.490614,78350.0%47.9%
47.85%2096.689514,51947.4%48.2%
51.20%2096.291414,69254.9%47.7%
47.29%2036.691414,23847.6%47.0%
41.48%1766.590814,43639.7%42.7%
50.90%1676.598714,86345.6%55.7%
54.30%1516.697515,18559.4%50.6%
51.05%1436.595014,37048.6%53.4%
52.29%1096.493214,22061.8%42.6%
48.60%1076.791213,41050.0%46.7%
53.95%766.292814,89060.6%48.8%
51.35%746.599614,13950.0%53.6%
52.11%716.593614,17758.5%43.3%
47.06%686.592213,35648.6%45.2%
50.00%686.51,00214,17644.1%55.9%
39.68%636.585114,52846.7%33.3%
57.89%576.795514,70461.5%54.8%
28.26%466.379911,46420.7%41.2%
41.86%436.287113,14330.8%58.8%
37.21%436.889313,07632.1%46.7%
45.95%376.31,09714,94644.4%47.4%
33.33%366.372112,47938.1%26.7%
60.00%306.778912,92650.0%71.4%
43.33%306.41,11316,25357.1%31.3%
53.33%306.195015,50341.7%61.1%
53.57%286.31,02214,25046.7%61.5%
46.15%266.61,02014,48350.0%41.7%
44.00%256.690012,73633.3%53.9%
36.36%226.197915,94330.0%41.7%
50.00%186.480112,39644.4%55.6%
42.86%146.779012,77542.9%42.9%
46.15%136.789414,31157.1%33.3%
75.00%126.51,06815,32066.7%83.3%
50.00%86.774513,13550.0%50.0%
28.57%76.593111,49820.0%50.0%
66.67%66.287413,9790.0%80.0%
16.67%66.298913,1600.0%33.3%
33.33%66.581713,03566.7%0.0%
0.00%65.956410,7450.0%0.0%
60.00%56.187611,48966.7%50.0%

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Samira vs Vayne - Frequently Asked Questions

How does Samira do against Vayne in League of Legends?

Samira wins the Samira vs Vayne matchup with a 52.3% win rate compared to Vayne's 47.7%, a 4.6 percentage point difference. This data is based on 109 recent ranked games in patch 26.7.

How does Samira do against Vayne in the early game?

In the early game, Samira has the advantage against Vayne with a 61.8% win rate versus 38.2%. Samira players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Samira do against Vayne in the late game?

In the late game, Vayne takes over the Samira vs Vayne matchup with a 57.4% win rate compared to 42.6%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Samira vs Vayne matchup?

Samira wins the matchup against Vayne with a 52.3% win rate in League of Legends patch 26.7. The 4.6 percentage point advantage means Samira is moderately favored in this lane matchup based on 109 games analyzed.

What is the best Samira build against Vayne?

The best Samira build against Vayne includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Samira runes against Vayne?

The best Samira runes against Vayne use the Precision primary tree with Resolve secondary. This rune setup achieves a 63.6% win rate in the Samira vs Vayne matchup. See the full rune breakdown in the matchup comparison above.

Does Samira counter Vayne?

Yes, Samira has a favorable matchup against Vayne with a 52.3% win rate. Samira has a solid advantage over Vayne in lane based on current patch 26.7 data.

How do I play Samira against Vayne?

When playing Samira against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.