Samira - League of Legends Champion
Win Rate
49.5%
Pick Rate
2.7%

Samiravs Vayne

CMarksmanAssassin
Patch26.10
Matches3,169,061
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 30, 2026
MethodologyData Methodology

Samira vs Vayne is a very close matchup in LoL patch 26.10. Samira wins with a 50.8% win rate (+1.6%) over Vayne based on 189 games. Samira holds the advantage in both the early and late game. Below you'll find the best Samira build, runes, laning stats, and strategies for the Samira vs Vayne matchup.

MetaBot Desktop
Live In-Game Overlays
Join Our Discord
Bug reports, feature requests & developer chat
Join Discord

Samira Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Samira performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Samira - 50.8% win rate in this matchup
Samira
50.8% WR
VS
Vayne vs Samira matchup - 49.2% win rate
Vayne
49.2% WR

Who Wins the Samira vs Vayne Matchup?

Samira wins the Samira vs Vayne matchup
Winner
Samira
Matches: 189
50.8%
Win Rate
49.2%
6.4
CS / min
5.9
994
DMG / min
829
14,683
Gold / game
12,620
335
Heal / min
196
615
DMG Mitigated / min
464
0.1
CC / min
0.4
51.6%
Early Game WR
48.4%
50.0%
Late Game WR
50.0%

Samira vs Vayne Matchup Summary

The Samira vs Vayne matchup is a very close matchup in League of Legends ranked play. Based on 189 recent matches analyzed, Samira wins with a 50.8% win rate compared to Vayne's 49.2%, giving Samira a 1.6 percentage point advantage. Samira holds a slight edge in both the early and late game, but the margins are thin enough that individual skill and jungle attention will often determine the outcome. Vayne can still find windows through outplays and team coordination. The most significant statistical gap is in crowd control, where Vayne leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Samira has a statistical edge, but the margin is close enough that respecting Vayne's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Samira vs Vayne Laning Phase Breakdown

Samira wins the laning phase against Vayne in League of Legends

Samira is favored during the laning phase against Vayne, winning 4 out of 5 key stat categories. Samira holds advantages in farming, damage, gold income and sustain, making them the stronger laner in this matchup.

Farming
6.4Samira
5.9Vayne
Samira edges out Vayne by 0.5 CS per minute — a moderate farming advantage that adds up to roughly 7 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Samira.
Damage
994Samira
829Vayne
Samira heavily out-damages Vayne by 165 DMG/min, dominating both short trades and all-in fights. Vayne should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Samira's sustained damage advantage take over.
Economy
14,683Samira
12,620Vayne
Samira generates a commanding 2,062 more gold per game than Vayne. This substantial economic advantage means Samira consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Vayne should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.1Samira
0.4Vayne
Both Samira and Vayne provide similar amounts of crowd control (0.3s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
949Samira
660Vayne
Samira vastly out-sustains Vayne, healing and mitigating 289 more damage per minute. This massive durability gap means Samira can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Samira Build Against Vayne

Immortal Path is the optimal boots choice against Vayne, providing the mobility and stats Samira needs most in this matchup. The top-performing core items for Samira against Vayne are The Collector, Lord Dominik's Regards and Infinity Edge. This combination gives Samira an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Samira vs Vayne matchup.

Early Game vs Late Game

Early Game
Samira
51.6%
+3.2% advantage
Samira early game win rateSamira51.6%
Vayne early game win rateVayne48.4%
Late Game
Samira
50.0%
+0.0% advantage
Samira late game win rateSamira50.0%
Vayne late game win rateVayne50.0%

During the early laning phase (first 15 minutes), Samira has a meaningful 51.6% win rate, outperforming Vayne by 3.2 percentage points. Samira players should look to press this advantage through aggressive trades, wave priority, and early jungle coordination.

Late game (25+ minutes) is equally balanced, with Samira at 50.0% win rate — only 0.0 points ahead of Vayne. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

Samira holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Samira Runes Against Vayne

Precision rune tree - Samira primary runes vs VaynePrecision
Conqueror - best Samira rune vs VayneTriumph - best Samira rune vs VayneLegend: Bloodline - best Samira rune vs VayneLast Stand - best Samira rune vs Vayne
Domination rune tree - Samira secondary runes vs VayneDomination
Taste of Blood - best Samira rune vs VayneTreasure Hunter - best Samira rune vs Vayne
49.0% WR

The Precision primary with Domination secondary combination helps Samira maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Vayne.


Samira matchup data for League of Legends patch 26.10. The table below shows Samira's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Samira build, runes, laning stats, and early vs late game analysis for that specific matchup.

Samira matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
45.66%6926.593714,10550.3%42.1%
49.57%4686.385813,56249.5%49.6%
43.85%4476.485313,66642.1%45.6%
49.39%4096.186313,54248.3%50.2%
42.30%3836.486113,30942.3%42.3%
49.53%3176.391914,22545.9%52.6%
48.89%2706.387913,89643.2%54.4%
52.66%2076.597014,68949.4%55.1%
50.79%1896.499414,68351.6%50.0%
49.10%1676.390913,85945.2%53.0%
54.01%1376.382213,62253.5%54.5%
49.60%1256.289913,89645.2%54.0%
38.60%1146.278012,77238.3%38.9%
38.68%1066.582313,18139.3%38.0%
55.10%986.696315,15364.3%48.2%
48.39%936.694314,55647.8%48.9%
50.57%876.592613,57842.9%60.5%
50.00%866.493914,30946.0%53.1%
60.26%786.391714,65951.7%65.3%
44.87%786.286513,18744.4%45.2%
47.06%686.486412,83046.1%48.3%
56.67%606.388114,10551.4%64.0%
41.82%556.290613,44948.1%35.7%
59.26%546.788212,88756.3%63.6%
52.27%446.484613,52345.0%58.3%
44.19%436.190113,05538.1%50.0%
53.85%396.397313,30450.0%57.1%
41.94%316.185714,72543.8%40.0%
56.67%306.51,01113,73143.8%71.4%
44.83%296.379113,51150.0%38.5%
36.00%256.088214,17033.3%37.5%
30.43%236.471312,81833.3%27.3%
28.57%216.574513,73725.0%30.8%
52.63%196.378713,26157.1%50.0%
46.67%156.684515,03633.3%55.6%
53.33%156.488814,42820.0%70.0%
35.71%145.81,06814,02033.3%37.5%
58.33%126.585713,30816.7%100.0%
45.45%116.71,07010,67957.1%25.0%
45.45%116.91,13917,20975.0%28.6%
44.44%95.982814,05150.0%40.0%
50.00%86.197215,59250.0%50.0%
50.00%86.379912,22366.7%0.0%
12.50%85.880114,2070.0%16.7%
62.50%86.765012,05960.0%66.7%
42.86%76.569110,61350.0%0.0%
57.14%76.373215,5850.0%66.7%
50.00%64.35559,91025.0%100.0%
33.33%65.782711,47650.0%25.0%
80.00%55.776213,69366.7%100.0%
0.00%56.56298,6130.0%0.0%
20.00%55.655611,30033.3%0.0%
20.00%56.477611,2140.0%100.0%
40.00%56.21,04813,7630.0%100.0%

Get the MetaBot Desktop App

Level up your gameplay with real-time overlays, automatic game detection, and instant stats — all on your desktop.

In-game overlaysAuto game detectionMulti-game supportPersonal dashboard
Download NowFree download
🔍

Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.

Report an Issue

Samira vs Vayne - Frequently Asked Questions

How does Samira do against Vayne in League of Legends?

Samira wins the Samira vs Vayne matchup with a 50.8% win rate compared to Vayne's 49.2%, a 1.6 percentage point difference. This data is based on 189 recent ranked games in patch 26.10.

How does Samira do against Vayne in the early game?

In the early game, Samira has the advantage against Vayne with a 51.6% win rate versus 48.4%. Samira players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Samira do against Vayne in the late game?

In the late game, Samira takes over the Samira vs Vayne matchup with a 50.0% win rate compared to 50.0%. Samira scales better into team fights and objective contests after 25 minutes.

Who wins the Samira vs Vayne matchup?

Samira wins the matchup against Vayne with a 50.8% win rate in League of Legends patch 26.10. The 1.6 percentage point advantage means Samira is slightly favored in this lane matchup based on 189 games analyzed.

What is the best Samira build against Vayne?

The best Samira build against Vayne includes The Collector, Lord Dominik's Regards, Infinity Edge with Immortal Path. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Samira runes against Vayne?

The best Samira runes against Vayne use the Precision primary tree with Domination secondary. This rune setup achieves a 49.0% win rate in the Samira vs Vayne matchup. See the full rune breakdown in the matchup comparison above.

Does Samira counter Vayne?

Yes, Samira has a favorable matchup against Vayne with a 50.8% win rate. Samira slightly edges out Vayne in lane based on current patch 26.10 data.

How do I play Samira against Vayne?

When playing Samira against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.