Senna - League of Legends Champion
Win Rate
49.7%
Pick Rate
4.6%

Sennavs Karma

CSupportMarksman
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 20, 2026
MethodologyData Methodology

Senna vs Karma is a decisive matchup in LoL patch 26.7. Karma wins with a 55.6% win rate (+11.1%) over Senna based on 99 games. Senna wins the early laning phase while Karma scales better into the late game. Below you'll find the best Senna build, runes, laning stats, and strategies for the Senna vs Karma matchup.

Senna Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Senna performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karma - 44.4% win rateKarma(44.4%)
Senna - 44.4% win rate in this matchup
Senna
44.4% WR
VS
Karma vs Senna matchup - 55.6% win rate
Karma
55.6% WR

Who Wins the Senna vs Karma Matchup?

Karma wins the Senna vs Karma matchup
Winner
Karma
Matches: 99
44.4%
Win Rate
55.6%
1.4
CS / min
1.2
529
DMG / min
369
10,191
Gold / game
8,786
539
Heal / min
261
328
DMG Mitigated / min
467
1.3
CC / min
1.0
51.2%
Early Game WR
48.8%
39.7%
Late Game WR
60.3%

Senna vs Karma Matchup Summary

The Senna vs Karma matchup is a decisive matchup in League of Legends ranked play. Based on 99 recent matches analyzed, Karma wins with a 55.6% win rate compared to Senna's 44.4%, giving Karma a 11.1 percentage point advantage. Game phase dynamics play a critical role here: Senna controls the early laning stage, but Karma outscales as the game goes longer. The matchup shifts dramatically depending on game length — Senna needs to press advantages before Karma reaches their power spikes, while Karma should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in damage output, where Senna leads by 160 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Karma has a strong advantage in this matchup. Senna players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Karma overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Senna vs Karma Laning Phase Breakdown

Senna wins the laning phase against Karma in League of Legends

Senna is favored during the laning phase against Karma, winning 5 out of 5 key stat categories. Senna holds advantages in farming, damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
1.4Senna
1.2Karma
Senna and Karma farm at nearly identical rates in this matchup, with only a 0.3 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
529Senna
369Karma
Senna heavily out-damages Karma by 160 DMG/min, dominating both short trades and all-in fights. Karma should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Senna's sustained damage advantage take over.
Economy
10,191Senna
8,786Karma
Senna generates a commanding 1,404 more gold per game than Karma. This substantial economic advantage means Senna consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Karma should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.3Senna
1.0Karma
Both Senna and Karma provide similar amounts of crowd control (0.3s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
866Senna
728Karma
Senna heals and mitigates 138 more damage per minute than Karma, providing moderate extra durability. This sustain edge allows Senna to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Karma.

Best Senna Build Against Karma

Boots of Swiftness is the optimal boots choice against Karma, providing the mobility and stats Senna needs most in this matchup. The top-performing core items for Senna against Karma are Serpent's Fang, Rapid Firecannon and Black Cleaver. This combination gives Senna an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 55.6% win rate across 9 games — well above average and making it the top item path against Karma. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Senna vs Karma matchup.

Early Game vs Late Game

Early Game
Senna
51.2%
+2.4% advantage
Senna early game win rateSenna51.2%
Karma early game win rateKarma48.8%
Late Game
Karma
60.3%
+20.7% advantage
Senna late game win rateSenna39.7%
Karma late game win rateKarma60.3%

During the early laning phase (first 15 minutes), Senna has a meaningful 51.2% win rate, outperforming Karma by 2.4 percentage points. Senna players should look to press this advantage through aggressive trades, wave priority, and early jungle coordination.

Karma is far superior in the late game (25+ minutes), boasting a 60.3% win rate — 20.7 points above Senna. Extended games heavily favor Karma, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Senna has the edge early, but Karma gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Senna Runes Against Karma

Resolve rune tree - Senna primary runes vs KarmaResolve
Grasp of the Undying - best Senna rune vs KarmaFont of Life - best Senna rune vs KarmaBone Plating - best Senna rune vs KarmaRevitalize - best Senna rune vs Karma
Precision rune tree - Senna secondary runes vs KarmaPrecision
Legend: Alacrity - best Senna rune vs KarmaPresence of Mind - best Senna rune vs Karma
40.0% WR

The Resolve and Precision rune setup gives Senna the best tools to compete against Karma in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Senna matchup data for League of Legends patch 26.7. The table below shows Senna's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Senna build, runes, laning stats, and early vs late game analysis for that specific matchup.

Senna matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.56%2251.455810,21750.0%45.5%
51.38%1811.557710,53146.8%54.8%
50.89%1695.577513,46844.9%55.0%
53.85%1691.655010,89748.6%57.9%
48.43%1591.651810,03745.7%50.6%
46.48%1425.977213,18240.9%51.3%
53.96%1391.556610,21550.8%56.9%
46.46%1271.558510,35650.0%43.8%
59.68%1241.557610,15460.0%59.4%
58.47%1181.45839,95557.1%59.7%
49.57%1156.587813,88151.9%47.5%
50.88%1145.981612,83553.6%48.3%
49.12%1146.178212,78941.5%55.7%
48.62%1092.367910,70336.6%55.9%
52.34%1076.288313,40056.1%48.0%
43.40%1066.184713,35437.5%48.3%
44.44%991.452910,19151.2%39.7%
50.51%991.657710,15046.9%54.0%
42.55%941.452910,51535.1%47.4%
48.84%861.45719,95844.2%53.5%
54.12%851.555710,24150.0%57.8%
49.38%816.078412,43353.5%44.7%
57.69%781.44659,34560.9%53.1%
48.68%762.355811,16840.0%54.4%
52.05%731.46059,89852.5%51.5%
44.44%726.288013,61254.8%36.6%
56.94%722.758511,20638.7%70.7%
42.86%701.45219,61243.6%41.9%
59.70%671.45689,46151.4%68.8%
56.45%621.755910,86863.6%52.5%
50.00%626.178013,00832.1%64.7%
42.11%571.950310,77833.3%47.2%
56.36%552.153811,59855.6%56.8%
47.06%511.46859,61034.6%60.0%
54.90%511.366410,89141.7%66.7%
48.00%501.665310,52550.0%46.1%
45.83%485.679114,32253.3%42.4%
51.06%475.784912,93544.0%59.1%
53.33%456.175013,70643.8%58.6%
58.14%436.384512,97069.2%41.2%
39.02%411.559310,86537.5%40.0%
43.59%391.569712,29841.7%44.4%
48.72%391.56049,81963.6%29.4%
60.00%356.589014,81666.7%56.5%
40.00%351.464010,05850.0%31.6%
55.88%341.35429,23359.1%50.0%
51.61%316.187513,86036.8%75.0%
50.00%281.754410,52950.0%50.0%
60.71%286.490314,33153.9%66.7%
50.00%263.374512,44637.5%55.6%
41.67%246.184613,02233.3%50.0%
50.00%242.157311,24850.0%50.0%
45.45%221.462710,22355.6%38.5%
63.64%226.277813,82480.0%50.0%
42.86%215.574611,73750.0%33.3%
55.00%206.295213,00370.0%40.0%
50.00%206.988813,62854.5%44.4%
50.00%185.272912,60662.5%40.0%
66.67%181.259210,65971.4%63.6%
64.71%171.871211,27677.8%50.0%
26.67%151.85137,91340.0%0.0%
46.15%133.059410,69233.3%57.1%
38.46%136.282613,43142.9%33.3%
50.00%122.062411,59980.0%28.6%
58.33%125.754212,02366.7%33.3%
58.33%121.46798,55860.0%57.1%
36.36%111.44259,59016.7%60.0%
72.73%114.51,01110,58860.0%83.3%
45.45%111.84269,88240.0%50.0%
63.64%112.961811,07460.0%66.7%
40.00%106.083613,30460.0%20.0%
60.00%102.356210,70160.0%60.0%
50.00%103.678010,68960.0%40.0%
77.78%96.677114,58380.0%75.0%
66.67%92.276511,77650.0%71.4%
25.00%83.669611,5340.0%40.0%
75.00%81.353712,18466.7%80.0%
37.50%81.169011,5090.0%50.0%
14.29%73.665310,92850.0%0.0%
71.43%71.25269,68875.0%66.7%
50.00%64.866012,36766.7%33.3%
40.00%54.373311,81033.3%50.0%
0.00%52.95609,6090.0%0.0%
60.00%56.470814,61333.3%100.0%
60.00%52.975613,365100.0%50.0%
60.00%56.276314,10050.0%66.7%
40.00%51.745511,50350.0%33.3%
60.00%52.379614,391100.0%50.0%

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Senna vs Karma - Frequently Asked Questions

How does Senna do against Karma in League of Legends?

Karma wins the Senna vs Karma matchup with a 55.6% win rate compared to Senna's 44.4%, a 11.1 percentage point difference. This data is based on 99 recent ranked games in patch 26.7.

How does Senna do against Karma in the early game?

In the early game, Senna has the advantage against Karma with a 51.2% win rate versus 48.8%. Senna players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Senna do against Karma in the late game?

In the late game, Karma takes over the Senna vs Karma matchup with a 60.3% win rate compared to 39.7%. Karma scales better into team fights and objective contests after 25 minutes.

Who wins the Senna vs Karma matchup?

Karma wins the matchup against Senna with a 55.6% win rate in League of Legends patch 26.7. The 11.1 percentage point advantage means Karma is significantly favored in this lane matchup based on 99 games analyzed.

What is the best Senna build against Karma?

The best Senna build against Karma includes Serpent's Fang, Rapid Firecannon, Black Cleaver with Boots of Swiftness. This build achieves a 55.6% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Senna runes against Karma?

The best Senna runes against Karma use the Resolve primary tree with Precision secondary. This rune setup achieves a 40.0% win rate in the Senna vs Karma matchup. See the full rune breakdown in the matchup comparison above.

Does Senna counter Karma?

No, Senna struggles against Karma with only a 44.4% win rate. Karma has the advantage in this matchup. Senna players should focus on safe farming and avoiding extended trades to minimize Karma's lead.

How do I play Senna against Karma?

When playing Senna against Karma, play cautiously and avoid Karma's power spikes. Look for jungle assistance and team-dependent plays since Karma has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.