Senna - League of Legends Champion
Win Rate
51.7%
Pick Rate
6.7%

Sennavs Karma

SSupportMarksman
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 6, 2026
MethodologyData Methodology

Senna vs Karma is a very close matchup in LoL patch 26.11. Senna wins with a 50.3% win rate (+0.7%) over Karma based on 145 games. Karma wins the early laning phase while Senna scales better into the late game. Below you'll find the best Senna build, runes, laning stats, and strategies for the Senna vs Karma matchup.

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Senna Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Senna performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Senna - 50.3% win rate in this matchup
Senna
50.3% WR
VS
Karma vs Senna matchup - 49.7% win rate
Karma
49.7% WR

Who Wins the Senna vs Karma Matchup?

Senna wins the Senna vs Karma matchup
Winner
Senna
Matches: 145
50.3%
Win Rate
49.7%
1.5
CS / min
1.3
567
DMG / min
410
9,579
Gold / game
8,470
458
Heal / min
223
329
DMG Mitigated / min
468
1.2
CC / min
1.0
48.6%
Early Game WR
51.4%
52.0%
Late Game WR
48.0%

Senna vs Karma Matchup Summary

The Senna vs Karma matchup is essentially a coin-flip matchup in League of Legends ranked play. Based on 145 recent matches analyzed, Senna wins with a 50.3% win rate compared to Karma's 49.7%, giving Senna a 0.7 percentage point advantage. Game phase dynamics play a critical role here: Karma controls the early laning stage, but Senna outscales as the game goes longer. The matchup shifts dramatically depending on game length — Karma needs to press advantages before Senna reaches their power spikes, while Senna should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in damage output, where Senna leads by 157 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Senna has a statistical edge, but the margin is close enough that respecting Karma's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Senna vs Karma Laning Phase Breakdown

Senna wins the laning phase against Karma in League of Legends

Senna is favored during the laning phase against Karma, winning 5 out of 5 key stat categories. Senna holds advantages in farming, damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
1.5Senna
1.3Karma
Senna and Karma farm at nearly identical rates in this matchup, with only a 0.3 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
567Senna
410Karma
Senna heavily out-damages Karma by 157 DMG/min, dominating both short trades and all-in fights. Karma should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Senna's sustained damage advantage take over.
Economy
9,579Senna
8,470Karma
Senna generates a commanding 1,109 more gold per game than Karma. This substantial economic advantage means Senna consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Karma should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.2Senna
1.0Karma
Both Senna and Karma provide similar amounts of crowd control (0.3s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
786Senna
692Karma
Senna heals and mitigates 95 more damage per minute than Karma, providing moderate extra durability. This sustain edge allows Senna to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Karma.

Best Senna Build Against Karma

Boots of Swiftness is the optimal boots choice against Karma, providing the mobility and stats Senna needs most in this matchup. The top-performing core items for Senna against Karma are Serpent's Fang, Rapid Firecannon and Black Cleaver. This combination gives Senna an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 3 games — well above average and making it the top item path against Karma. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Senna vs Karma matchup.

Early Game vs Late Game

Early Game
Karma
51.4%
+2.9% advantage
Senna early game win rateSenna48.6%
Karma early game win rateKarma51.4%
Late Game
Senna
52.0%
+4.0% advantage
Senna late game win rateSenna52.0%
Karma late game win rateKarma48.0%

During the early laning phase (first 15 minutes), Karma has a meaningful 51.4% win rate, outperforming Senna by 2.9 percentage points. Karma players should look to press this advantage through aggressive trades, wave priority, and early jungle coordination.

In the late game (25+ minutes), Senna takes over with a 52.0% win rate, leading Karma by 4.0 percentage points. Senna scales more effectively into team fights and objective contests.

The power dynamics shift as the game progresses — Karma has the edge early, but Senna gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Senna Runes Against Karma

Sorcery rune tree - Senna primary runes vs KarmaSorcery
Deathfire Touch - best Senna rune vs KarmaManaflow Band - best Senna rune vs KarmaCelerity - best Senna rune vs KarmaGathering Storm - best Senna rune vs Karma
Inspiration rune tree - Senna secondary runes vs KarmaInspiration
Jack Of All Trades - best Senna rune vs KarmaMagical Footwear - best Senna rune vs Karma
60.7% WR

The Sorcery primary with Inspiration secondary combination helps Senna maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Karma.


Senna matchup data for League of Legends patch 26.11. The table below shows Senna's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Senna build, runes, laning stats, and early vs late game analysis for that specific matchup.

Senna matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.79%4781.960010,12548.4%51.0%
52.43%3916.179712,53348.4%56.2%
46.98%3642.054810,60839.5%52.4%
48.42%3491.662910,54949.0%48.0%
48.37%3375.575412,57847.1%49.5%
57.41%3241.663110,72759.7%55.4%
56.72%3056.291713,61461.5%53.5%
47.47%2971.662710,06144.8%50.0%
43.99%2911.665510,02748.1%40.4%
48.42%2856.081512,84951.2%46.3%
54.78%2726.079212,82650.4%57.9%
51.22%2461.666910,98850.0%52.0%
50.21%2372.863011,28545.3%53.5%
59.31%2315.881312,72658.2%60.3%
54.78%2305.676612,74653.3%56.1%
47.74%1991.669610,23542.2%52.3%
44.92%1871.55659,75657.0%36.1%
54.29%1751.663010,66554.0%54.5%
47.13%1571.662510,80255.9%41.8%
47.30%1481.65929,98050.0%44.3%
50.34%1451.55679,57948.6%52.0%
56.64%1431.783210,66665.2%49.4%
60.84%1436.180113,09759.7%61.8%
52.11%1422.158810,86046.1%55.6%
57.55%1391.558910,21856.9%58.1%
59.42%1381.566510,31160.9%58.1%
43.70%1351.858010,86638.1%46.2%
54.40%1251.46479,76056.7%52.3%
59.35%1231.566610,24255.0%63.5%
55.37%1212.379511,32252.8%57.4%
53.33%1201.869710,47044.9%59.1%
38.98%1182.558210,15332.1%44.6%
57.39%1156.085912,79566.0%50.8%
56.25%1122.765611,46458.3%54.7%
49.53%1075.573211,86550.0%49.1%
56.60%1061.561410,59463.6%51.6%
50.48%1055.976412,78847.7%52.5%
47.96%981.564610,27358.8%36.2%
49.48%971.673710,10051.9%46.5%
52.63%955.982212,59348.9%56.0%
43.68%871.562810,13445.5%41.9%
60.92%875.882512,77061.0%60.9%
47.62%845.887913,30047.2%47.9%
50.00%766.176712,54553.9%46.0%
56.34%711.664310,67355.6%56.8%
53.62%696.186213,25554.8%52.6%
55.22%671.771310,55956.3%54.3%
41.27%631.658210,00632.4%51.7%
40.98%615.979512,54952.0%33.3%
56.14%576.276913,36750.0%60.0%
39.29%566.484312,19240.6%37.5%
53.70%541.571010,49847.6%57.6%
42.31%522.556210,81438.9%44.1%
36.17%474.569212,29931.6%39.3%
57.78%451.75939,92565.2%50.0%
68.18%441.773011,13881.3%60.7%
54.55%446.091013,57950.0%57.1%
50.00%445.676812,22952.6%48.0%
55.81%431.871310,57870.6%46.1%
48.65%375.469212,02433.3%59.1%
52.78%362.071510,73861.1%44.4%
37.14%352.15849,96329.4%44.4%
54.55%333.970812,05214.3%65.4%
48.28%296.195313,54861.5%37.5%
67.86%285.477412,98083.3%56.3%
37.04%271.85929,93950.0%23.1%
56.00%252.364211,17140.0%66.7%
52.17%236.286012,42638.5%70.0%
52.38%216.190314,07744.4%58.3%
61.90%211.95968,42871.4%42.9%
40.00%201.566410,93657.1%30.8%
52.63%192.166110,75344.4%60.0%
52.94%172.883712,69557.1%50.0%
23.53%176.288414,68320.0%25.0%
35.29%175.070612,60114.3%50.0%
43.75%162.365011,94133.3%50.0%
53.33%152.14989,50237.5%71.4%
57.14%142.877211,70271.4%42.9%
42.86%141.75598,86612.5%83.3%
42.86%145.986914,09975.0%30.0%
63.64%116.888712,05550.0%100.0%
45.45%113.772011,78820.0%66.7%
72.73%114.262112,093100.0%62.5%
50.00%103.084610,73050.0%50.0%
60.00%101.86159,07050.0%66.7%
50.00%103.794911,81460.0%40.0%
60.00%102.080412,39150.0%62.5%
50.00%101.76249,60125.0%66.7%
30.00%101.963411,3180.0%42.9%
40.00%105.774810,96740.0%40.0%
50.00%101.657110,36233.3%57.1%
70.00%103.066612,29650.0%83.3%
60.00%105.683813,4100.0%66.7%
66.67%95.956111,32766.7%66.7%
33.33%94.384213,14625.0%40.0%
100.00%92.877610,063100.0%100.0%
44.44%91.86659,94975.0%20.0%
25.00%84.56159,76033.3%20.0%
62.50%82.977911,74950.0%75.0%
25.00%83.55048,14150.0%0.0%
14.29%71.56258,8820.0%33.3%
42.86%74.864610,22233.3%50.0%
42.86%74.91,19511,30533.3%50.0%
28.57%73.958311,6790.0%50.0%
33.33%63.75588,16925.0%50.0%
33.33%61.867512,09650.0%25.0%
83.33%62.847011,681100.0%75.0%
33.33%63.862712,5550.0%40.0%
50.00%64.377213,79866.7%33.3%
33.33%61.956810,50450.0%25.0%
40.00%53.17859,31033.3%50.0%
80.00%51.48609,54666.7%100.0%
60.00%53.275111,74766.7%50.0%
20.00%54.85999,3190.0%50.0%
40.00%54.970312,9070.0%40.0%
40.00%52.18638,0880.0%66.7%
60.00%53.847512,861100.0%0.0%
20.00%55.61,02111,3140.0%50.0%
20.00%54.96469,34225.0%0.0%
80.00%55.389713,097100.0%66.7%
80.00%55.486011,002100.0%50.0%
80.00%53.05319,58866.7%100.0%
60.00%54.758111,34450.0%66.7%

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Senna vs Karma - Frequently Asked Questions

How does Senna do against Karma in League of Legends?

Senna wins the Senna vs Karma matchup with a 50.3% win rate compared to Karma's 49.7%, a 0.7 percentage point difference. This data is based on 145 recent ranked games in patch 26.11.

How does Senna do against Karma in the early game?

In the early game, Karma has the advantage against Senna with a 51.4% win rate versus 48.6%. Karma players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Senna do against Karma in the late game?

In the late game, Senna takes over the Senna vs Karma matchup with a 52.0% win rate compared to 48.0%. Senna scales better into team fights and objective contests after 25 minutes.

Who wins the Senna vs Karma matchup?

Senna wins the matchup against Karma with a 50.3% win rate in League of Legends patch 26.11. The 0.7 percentage point advantage means Senna is slightly favored in this lane matchup based on 145 games analyzed.

What is the best Senna build against Karma?

The best Senna build against Karma includes Serpent's Fang, Rapid Firecannon, Black Cleaver with Boots of Swiftness. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Senna runes against Karma?

The best Senna runes against Karma use the Sorcery primary tree with Inspiration secondary. This rune setup achieves a 60.7% win rate in the Senna vs Karma matchup. See the full rune breakdown in the matchup comparison above.

Does Senna counter Karma?

Yes, Senna has a favorable matchup against Karma with a 50.3% win rate. Senna slightly edges out Karma in lane based on current patch 26.11 data.

How do I play Senna against Karma?

When playing Senna against Karma, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Karma. Build the recommended items and runes for this specific matchup for the best results.