Senna - League of Legends Champion
Win Rate
52.0%
Pick Rate
6.5%

Sennavs Vex

SSupportMarksman
Patch26.10
Matches900,877
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 18, 2026
MethodologyData Methodology

Senna vs Vex is a decisive matchup in LoL patch 26.10. Senna wins with a 60.0% win rate (+20.0%) over Vex based on 5 games. Senna holds the advantage in both the early and late game. Below you'll find the best Senna build, runes, laning stats, and strategies for the Senna vs Vex matchup.

Senna Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Senna performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vex - 60.0% win rateVex(60.0%)
Senna - 60.0% win rate in this matchup
Senna
60.0% WR
VS
Vex vs Senna matchup - 40.0% win rate
Vex
40.0% WR

Who Wins the Senna vs Vex Matchup?

Senna wins the Senna vs Vex matchup
Winner
Senna
Matches: 5
60.0%
Win Rate
40.0%
2.8
CS / min
3.7
651
DMG / min
827
10,842
Gold / game
10,977
479
Heal / min
128
396
DMG Mitigated / min
522
1.4
CC / min
1.1
50.0%
Early Game WR
50.0%
66.7%
Late Game WR
33.3%

Senna vs Vex Matchup Summary

The Senna vs Vex matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Senna wins with a 60.0% win rate compared to Vex's 40.0%, giving Senna a 20.0 percentage point advantage. Senna dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vex players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Senna leads by 225 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Senna players can confidently pick into Vex and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vex away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Senna vs Vex Laning Phase Breakdown

Vex wins the laning phase against Senna in League of Legends

Vex is favored during the laning phase against Senna, winning 3 out of 5 key stat categories. Vex holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
2.8Senna
3.7Vex
Vex significantly out-farms Senna by 0.9 CS per minute, accumulating an estimated 14 CS lead by mid game. This substantial farming gap gives Vex a major gold advantage and earlier item completions. Senna players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
651Senna
827Vex
Vex heavily out-damages Senna by 176 DMG/min, dominating both short trades and all-in fights. Senna should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vex's sustained damage advantage take over.
Economy
10,842Senna
10,977Vex
Senna and Vex generate nearly equal gold per game, with just a 135 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
1.4Senna
1.1Vex
Senna provides 0.3 seconds more crowd control per minute than Vex, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Senna coordinate with their jungler and control the pace of skirmishes.
Sustain
875Senna
650Vex
Senna vastly out-sustains Vex, healing and mitigating 225 more damage per minute. This massive durability gap means Senna can absorb significant punishment and remain in lane while Vex is forced to recall. Building grievous wounds early is essential for Vex, and focusing on burst trade patterns rather than sustained fights is critical.

Best Senna Build Against Vex

Swiftmarch is the optimal boots choice against Vex, providing the mobility and stats Senna needs most in this matchup. The top-performing core items for Senna against Vex are Statikk Shiv, Black Cleaver and Muramana. This combination gives Senna an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Vex. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Senna vs Vex matchup.

Early Game vs Late Game

Early Game
Senna
50.0%
+0.0% advantage
Senna early game win rateSenna50.0%
Vex early game win rateVex50.0%
Late Game
Senna
66.7%
+33.3% advantage
Senna late game win rateSenna66.7%
Vex late game win rateVex33.3%

The early game (first 15 minutes) is a toss-up between Senna and Vex, with Senna holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Senna is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Vex. Extended games heavily favor Senna, whose kit and scaling make them a dominant force in team fights and objective control.

Senna holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vex players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Senna Runes Against Vex

Sorcery rune tree - Senna primary runes vs VexSorcery
Summon Aery - best Senna rune vs VexManaflow Band - best Senna rune vs VexTranscendence - best Senna rune vs VexScorch - best Senna rune vs Vex
Resolve rune tree - Senna secondary runes vs VexResolve
Font of Life - best Senna rune vs VexRevitalize - best Senna rune vs Vex
100.0% WR

Running Sorcery primary with Resolve secondary allows Senna to press their advantage against Vex, amplifying the strengths that make this a favorable matchup.


Senna matchup data for League of Legends patch 26.10. The table below shows Senna's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Senna build, runes, laning stats, and early vs late game analysis for that specific matchup.

Senna matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.09%6071.757710,09343.4%53.3%
51.46%4781.663110,02751.3%51.7%
47.68%4746.289913,40845.6%49.1%
53.90%4361.854310,26344.2%60.8%
52.90%4141.560310,08748.7%56.4%
52.81%3925.372911,91151.5%53.7%
50.84%3581.557910,05449.1%52.4%
52.33%3446.076312,95654.2%51.0%
49.22%3192.364811,18947.9%50.0%
49.08%2731.661610,13146.7%51.0%
47.91%2631.763810,80548.0%47.9%
47.33%2431.56219,52948.0%46.6%
46.44%2391.55859,90553.9%39.5%
50.00%2341.660910,70348.4%51.1%
48.91%2291.56369,57548.8%49.1%
45.74%2236.081212,89443.7%47.5%
50.46%2185.976912,85154.1%48.1%
54.55%2091.658810,05152.2%56.4%
55.45%2025.782213,10150.0%59.3%
50.52%1945.477212,68350.0%50.9%
55.67%1941.661610,20655.6%55.8%
50.79%1891.553810,13460.5%43.5%
60.44%1821.861110,80056.5%62.8%
50.28%1811.856610,80752.0%49.1%
50.28%1792.167610,90260.0%45.4%
55.11%1761.762410,16757.5%53.1%
56.65%1731.564410,23159.5%53.9%
53.94%1651.55789,72955.3%52.5%
56.52%1611.570110,37750.0%62.6%
48.75%1601.77599,63455.0%42.5%
55.13%1561.958510,63344.1%61.9%
54.10%1222.562911,10851.2%55.7%
51.69%1186.083412,88048.3%55.2%
50.43%1156.084613,54461.2%42.4%
49.49%991.560610,02960.8%37.5%
52.58%971.55699,77555.3%50.0%
50.00%921.570310,82954.0%47.3%
46.59%885.982313,41552.6%42.0%
45.45%881.666210,33762.8%28.9%
54.12%856.485613,33460.0%48.9%
51.76%856.185213,05054.5%50.0%
57.83%831.566010,12563.2%53.3%
58.54%821.566110,80355.6%60.9%
47.95%732.562811,15846.1%48.9%
56.34%711.863611,32040.0%65.2%
54.29%705.060211,30460.6%48.6%
48.53%685.780411,59751.4%45.2%
44.78%675.665011,46538.7%50.0%
42.19%641.762810,77134.6%47.4%
57.81%646.585413,24248.3%65.7%
69.09%551.668911,15176.2%64.7%
45.28%536.378311,56446.7%43.5%
64.15%533.364010,69261.9%65.6%
49.06%536.383812,69337.0%61.5%
47.06%515.679012,42938.1%53.3%
50.98%511.560810,17858.3%44.4%
52.08%482.365710,77957.9%48.3%
50.00%485.886013,64735.7%55.9%
57.78%451.47009,80063.6%52.2%
58.14%432.263910,77050.0%62.1%
51.28%395.170412,30826.7%66.7%
35.90%392.566111,40130.8%38.5%
47.22%365.579313,48350.0%45.8%
30.56%362.861111,06433.3%29.2%
45.45%336.291614,12750.0%42.1%
43.75%325.677912,84823.1%57.9%
58.06%312.776210,68453.3%62.5%
60.00%302.457510,00857.1%62.5%
27.59%295.976711,02723.5%33.3%
57.14%285.277011,64068.8%41.7%
47.62%211.65679,51254.5%40.0%
52.38%213.080712,899100.0%44.4%
52.38%216.095713,07150.0%54.5%
47.62%211.85649,61254.5%40.0%
65.00%201.960410,61950.0%80.0%
35.00%201.864411,13942.9%30.8%
57.89%193.264211,26066.7%53.9%
42.11%191.85479,94944.4%40.0%
63.16%191.76769,85022.2%100.0%
55.56%182.065111,80475.0%40.0%
50.00%183.082210,74028.6%63.6%
58.82%175.879410,71963.6%50.0%
50.00%163.293813,72325.0%58.3%
50.00%141.46389,54437.5%66.7%
71.43%143.875712,10880.0%66.7%
28.57%141.65819,89940.0%22.2%
53.85%135.782510,69450.0%55.6%
61.54%134.568412,16780.0%50.0%
58.33%121.773111,71860.0%57.1%
41.67%122.067512,4470.0%45.5%
50.00%122.476912,55640.0%57.1%
33.33%125.662713,34720.0%42.9%
41.67%125.288211,10540.0%42.9%
54.55%114.974014,02866.7%50.0%
36.36%112.37559,40133.3%40.0%
40.00%105.07339,12157.1%0.0%
50.00%104.06858,77257.1%33.3%
70.00%101.26769,87480.0%60.0%
80.00%102.17149,31380.0%80.0%
44.44%94.070710,714100.0%37.5%
66.67%92.566310,60171.4%50.0%
33.33%94.15358,05020.0%50.0%
66.67%91.676812,366100.0%57.1%
44.44%94.971011,8220.0%57.1%
37.50%83.662012,64750.0%33.3%
50.00%84.988713,464100.0%42.9%
50.00%84.580512,4340.0%57.1%
42.86%74.587214,1390.0%50.0%
42.86%73.164611,01850.0%40.0%
57.14%72.25489,11950.0%100.0%
28.57%75.080110,7720.0%50.0%
28.57%74.067011,13066.7%0.0%
66.67%64.262511,06775.0%50.0%
33.33%64.872211,02250.0%25.0%
66.67%61.782912,753100.0%50.0%
33.33%65.29658,6400.0%66.7%
16.67%66.45123,76616.7%0.0%
33.33%65.36549,85933.3%33.3%
66.67%63.588714,183100.0%60.0%
50.00%66.08408,16050.0%50.0%
66.67%62.174611,26150.0%75.0%
60.00%53.783013,253100.0%50.0%
60.00%52.865110,84250.0%66.7%
40.00%53.33916,57340.0%0.0%
20.00%51.45177,98433.3%0.0%
40.00%54.11,13711,4920.0%50.0%
100.00%51.65639,168100.0%100.0%
60.00%52.35599,29160.0%0.0%
20.00%51.74248,39633.3%0.0%
40.00%54.876211,9830.0%66.7%
60.00%54.762811,4450.0%75.0%

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Senna vs Vex - Frequently Asked Questions

How does Senna do against Vex in League of Legends?

Senna wins the Senna vs Vex matchup with a 60.0% win rate compared to Vex's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.

How does Senna do against Vex in the early game?

In the early game, Senna has the advantage against Vex with a 50.0% win rate versus 50.0%. Senna players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Senna do against Vex in the late game?

In the late game, Senna takes over the Senna vs Vex matchup with a 66.7% win rate compared to 33.3%. Senna scales better into team fights and objective contests after 25 minutes.

Who wins the Senna vs Vex matchup?

Senna wins the matchup against Vex with a 60.0% win rate in League of Legends patch 26.10. The 20.0 percentage point advantage means Senna is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Senna build against Vex?

The best Senna build against Vex includes Statikk Shiv, Black Cleaver, Muramana with Swiftmarch. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Senna runes against Vex?

The best Senna runes against Vex use the Sorcery primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Senna vs Vex matchup. See the full rune breakdown in the matchup comparison above.

Does Senna counter Vex?

Yes, Senna has a favorable matchup against Vex with a 60.0% win rate. Senna strongly counters Vex in lane based on current patch 26.10 data.

How do I play Senna against Vex?

When playing Senna against Vex, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.