- Win Rate
- 0%
- Pick Rate
- 0%
- Ban Rate
- 15.4%
Seraphine Mid Runes: Keystone & Shards
- Patch
- 26.20
- Matches
- 893,080
- Lane
- Mid
- Tier
- All Tiers
- Last Updated
- Oct 16, 2026 UTC
- Methodology
- Data Methodology
- Author
- Dakota Chinnick
Best Mid Seraphine runes for LoL Patch 26.20 - Keystone from the Primary tree with Secondary secondary (0% WR, 0% pick rate). Seraphine's optimal primary runes are {primaryRunes}. Secondary tree: {secondaryRunes}.
Primary Tree
Secondary Tree
Primary Tree
Secondary Tree
Every Seraphine Mid Keystone and Secondary Tree (Patch 26.20)
217 gamesSeraphine Mid runs Arcane Comet in 64% of games, with a 46.4% win rate. Inspiration is the usual secondary tree (37%). Standard stat shards: Ability Haste (offense), Adaptive Force (flex), Health (defense).
Keystones
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Arcane CometMost played | 63.6% | 46.4% | 138 |
Secondary trees
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 InspirationMost played | 37.3% | 48.1% | 81 |
 Precision | 30.0% | 46.2% | 65 |
Pick rate is the share of Seraphine games in this lane that used the rune; options under 40 games are left out. A higher win rate on a rarely picked rune is usually a matchup-specific choice, not a general upgrade.
Seraphine Minor Runes by Tree
Every minor rune Seraphine players take, grouped by rune tree, with how often it is picked and how often it wins.
Sorcery
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Manaflow BandMost played | 88.9% | 48.7% | 193 |
 Transcendence | 82.5% | 48.6% | 179 |
 Scorch | 56.7% | 48.0% | 123 |
 Gathering Storm | 33.6% | 49.3% | 73 |
Inspiration
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Cosmic InsightMost played | 34.6% | 45.3% | 75 |
 Biscuit Delivery | 32.7% | 46.5% | 71 |
Domination
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Ultimate HunterMost played | 22.1% | 52.1% | 48 |
 Cheap Shot | 19.8% | 46.5% | 43 |
Precision
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Legend: HasteMost played | 21.7% | 48.9% | 47 |
 Presence of Mind | 18.4% | 50.0% | 40 |
Seraphine Stat Shards
Which stat shards Seraphine players choose in each of the three shard rows, and the win rate of each.
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Adaptive Force (flex)Most played | 93.1% | 48.5% | 202 |
 Health (defense) | 71.0% | 46.1% | 154 |
 Ability Haste (offense) | 70.5% | 47.7% | 153 |
| Health Scaling (defense) | 24.0% | 55.8% | 52 |
| Adaptive Force (offense) | 21.7% | 55.3% | 47 |
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Seraphine Runes FAQ - Patch 26.20
What is the best keystone for Seraphine Mid?
Arcane Comet: Seraphine Mid takes it in 64% of ranked games and wins 46.4% of 138 games.
What stat shards should Seraphine take?
Most Seraphine players take Ability Haste (offense), Adaptive Force (flex), Health (defense) — one from each shard row.
What are the best Seraphine runes in patch 26.20?
The best Seraphine runes in patch 26.20 use the Primary tree with , and the Secondary tree with . This rune setup achieves a 0% win rate with a 0% pick rate.
What is the win rate for Seraphine's best rune page?
Seraphine's best rune page has a 0% win rate in patch 26.20, which is NaN% compared to Seraphine's average win rate. This rune setup has a 0% pick rate among Seraphine players.
What keystone should I use on Seraphine?
your chosen keystone from the Primary tree is the best keystone rune for Seraphine in patch 26.20. This keystone synergizes well with Seraphine's kit and provides a 0% win rate.
What is Seraphine's primary rune tree?
Seraphine's primary rune tree is Primary. The optimal Primary runes for Seraphine are , with your chosen keystone being the keystone of choice.
What is Seraphine's secondary rune tree?
Seraphine's best secondary rune tree is Secondary. The recommended Secondary runes are , which complement Seraphine's Primary primary tree.
What are alternative rune setups for Seraphine?
An alternative Seraphine rune setup uses alternative keystone from the Primary tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.
How popular are Seraphine's runes?
Seraphine's top rune page has a 0% pick rate in patch 26.20. This indicates that 0% of Seraphine players use the your chosen keystone setup with Primary and Secondary trees.