Zoe - League of Legends Champion
Win Rate
47.5%
Pick Rate
1.7%

Zoevs Syndra

FMage
Patch26.3
Matches785,220
LaneAll Lanes
TierAll Tiers
Last UpdatedFeb 26, 2026
MethodologyData Methodology

Zoe vs Syndra is a decisive matchup in LoL patch 26.3. Syndra wins with a 67.6% win rate (+35.2%) over Zoe based on 71 games. Syndra holds the advantage in both the early and late game. Below you'll find the best Zoe build, runes, laning stats, and strategies for the Zoe vs Syndra matchup.

Zoe Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Zoe performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Syndra - 32.4% win rateSyndra(32.4%)
Zoe - 32.4% win rate in this matchup
Zoe
32.4% WR
VS
Syndra vs Zoe matchup - 67.6% win rate
Syndra
67.6% WR

Who Wins the Zoe vs Syndra Matchup?

Syndra wins the Zoe vs Syndra matchup
Winner
Syndra
Matches: 71
32.4%
Win Rate
67.6%
6.0
CS / min
6.7
820
DMG / min
902
11,557
Gold / game
13,280
93
Heal / min
87
314
DMG Mitigated / min
306
1.1
CC / min
1.3
29.6%
Early Game WR
70.4%
34.1%
Late Game WR
65.9%

Zoe vs Syndra Matchup Summary

The Zoe vs Syndra matchup is a decisive matchup in League of Legends ranked play. Based on 71 recent matches analyzed, Syndra wins with a 67.6% win rate compared to Zoe's 32.4%, giving Syndra a 35.2 percentage point advantage. Syndra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Zoe players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Syndra leads by 0.2s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra has a strong advantage in this matchup. Zoe players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Syndra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Zoe vs Syndra Laning Phase Breakdown

Syndra wins the laning phase against Zoe in League of Legends

Syndra is favored during the laning phase against Zoe, winning 4 out of 5 key stat categories. Syndra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
6.0Zoe
6.7Syndra
Syndra edges out Zoe by 0.8 CS per minute — a moderate farming advantage that adds up to roughly 11 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Syndra.
Damage
820Zoe
902Syndra
Syndra heavily out-damages Zoe by 81 DMG/min, dominating both short trades and all-in fights. Zoe should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Syndra's sustained damage advantage take over.
Economy
11,557Zoe
13,280Syndra
Syndra generates a commanding 1,723 more gold per game than Zoe. This substantial economic advantage means Syndra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Zoe should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.1Zoe
1.3Syndra
Both Zoe and Syndra provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
406Zoe
393Syndra
Zoe and Syndra have comparable sustain profiles, with only 13 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Best Zoe Build Against Syndra

Spellslinger's Shoes is the optimal boots choice against Syndra, providing the mobility and stats Zoe needs most in this matchup. The top-performing core items for Zoe against Syndra are Luden's Echo, Shadowflame and Banshee's Veil. This combination gives Zoe an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 66.7% win rate across 3 games — well above average and making it the top item path against Syndra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Zoe vs Syndra matchup.

Early Game vs Late Game

Early Game
Syndra
70.4%
+40.7% advantage
Zoe early game win rateZoe29.6%
Syndra early game win rateSyndra70.4%
Late Game
Syndra
65.9%
+31.8% advantage
Zoe late game win rateZoe34.1%
Syndra late game win rateSyndra65.9%

Syndra dominates the early game (first 15 minutes) with a commanding 70.4% win rate — a 40.7 percentage point lead over Zoe. This lopsided early game means Syndra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Syndra is far superior in the late game (25+ minutes), boasting a 65.9% win rate — 31.8 points above Zoe. Extended games heavily favor Syndra, whose kit and scaling make them a dominant force in team fights and objective control.

Syndra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Zoe players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Zoe Runes Against Syndra

Domination rune tree - Zoe primary runes vs SyndraDomination
Dark Harvest - best Zoe rune vs SyndraSudden Impact - best Zoe rune vs SyndraGrisly Mementos - best Zoe rune vs SyndraRelentless Hunter - best Zoe rune vs Syndra
Sorcery rune tree - Zoe secondary runes vs SyndraSorcery
Nimbus Cloak - best Zoe rune vs SyndraTranscendence - best Zoe rune vs Syndra
42.9% WR

The Domination and Sorcery rune setup gives Zoe the best tools to compete against Syndra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Zoe matchup data for League of Legends patch 26.3. The table below shows Zoe's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zoe build, runes, laning stats, and early vs late game analysis for that specific matchup.

Zoe matchup win rates and stats in League of Legends patch 26.3
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
43.33%1505.988011,11949.3%37.3%
48.62%1095.787811,24137.8%56.3%
48.96%966.084211,87848.8%49.1%
56.25%805.698912,09357.6%55.3%
38.89%724.682110,72238.9%38.9%
32.39%716.082011,55729.6%34.1%
49.30%715.797511,82738.5%55.6%
58.73%635.786010,90553.1%64.5%
44.44%635.685110,71937.5%51.6%
47.46%595.692012,09836.4%54.0%
44.83%586.288911,36042.3%46.9%
57.89%575.489911,83843.5%67.7%
51.02%495.792911,87162.5%40.0%
40.43%475.693711,42357.9%28.6%
51.06%476.191410,49265.4%33.3%
43.48%461.47069,83533.3%52.0%
43.48%466.194812,07757.1%32.0%
59.09%445.994811,73179.0%44.0%
35.71%424.883811,25146.7%29.6%
36.59%413.875810,52236.8%36.4%
55.00%406.093112,58757.1%53.9%
40.00%406.394611,23642.3%35.7%
37.50%405.677010,37731.8%44.4%
39.47%385.91,02711,69255.6%25.0%
48.65%375.685010,93955.0%41.2%
51.35%375.684310,60044.4%57.9%
48.65%375.787311,60846.1%50.0%
50.00%365.483110,26657.9%41.2%
54.29%355.790211,44057.9%50.0%
29.03%315.91,00311,75313.3%43.8%
43.33%304.378010,22147.1%38.5%
58.62%291.674310,25060.0%57.1%
53.57%285.585010,03253.3%53.9%
40.74%274.584411,25314.3%50.0%
38.46%265.892611,34463.6%20.0%
57.69%265.990011,61971.4%41.7%
52.17%233.989211,46371.4%43.8%
39.13%236.31,01610,87545.5%33.3%
31.82%221.67089,41230.0%33.3%
71.43%216.51,07610,95785.7%42.9%
47.62%212.26629,37044.4%50.0%
42.86%211.76029,56545.5%40.0%
40.00%205.793811,08163.6%11.1%
45.00%201.36759,81336.4%55.6%
33.33%181.66589,38625.0%40.0%
52.94%171.475811,69750.0%54.5%
47.06%172.175410,90162.5%33.3%
68.75%166.796612,17285.7%55.6%
43.75%165.61,11312,36433.3%50.0%
46.67%152.675611,54433.3%50.0%
60.00%154.583010,59362.5%57.1%
60.00%156.792711,86066.7%50.0%
40.00%155.887111,46750.0%28.6%
33.33%154.873010,03637.5%28.6%
50.00%141.676010,88133.3%62.5%
57.14%142.17749,80762.5%50.0%
42.86%145.382510,21166.7%25.0%
64.29%146.079810,27162.5%66.7%
46.15%131.35038,52833.3%57.1%
38.46%131.55729,01344.4%25.0%
61.54%136.098511,917100.0%44.4%
53.85%132.973710,9890.0%70.0%
61.54%136.074010,13183.3%42.9%
58.33%121.572210,06560.0%57.1%
50.00%101.863310,83550.0%50.0%
50.00%101.67558,78780.0%20.0%
60.00%105.287514,31750.0%62.5%
66.67%91.780611,726100.0%62.5%
55.56%91.379210,838100.0%20.0%
22.22%96.51,07411,14040.0%0.0%
66.67%96.393012,264100.0%57.1%
55.56%95.98428,35666.7%33.3%
44.44%96.095611,22533.3%50.0%
75.00%82.87328,48480.0%66.7%
25.00%84.495512,1200.0%50.0%
37.50%81.48167,55660.0%0.0%
50.00%84.296113,57266.7%40.0%
42.86%74.27228,8450.0%100.0%
42.86%75.396512,86666.7%25.0%
28.57%75.885110,19333.3%25.0%
16.67%63.976910,6400.0%20.0%
33.33%62.16209,43533.3%33.3%
33.33%61.970010,7420.0%50.0%
33.33%65.47589,74350.0%0.0%
83.33%65.87818,13680.0%100.0%
80.00%52.171510,294100.0%66.7%
80.00%56.298913,578100.0%66.7%
40.00%53.973711,37066.7%0.0%
60.00%56.01,14811,79033.3%100.0%
80.00%51.75659,58866.7%100.0%
60.00%56.71,36913,79233.3%100.0%
60.00%51.57219,268100.0%0.0%
40.00%55.787110,20625.0%100.0%
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Zoe vs Syndra - Frequently Asked Questions

How does Zoe do against Syndra in League of Legends?

Syndra wins the Zoe vs Syndra matchup with a 67.6% win rate compared to Zoe's 32.4%, a 35.2 percentage point difference. This data is based on 71 recent ranked games in patch 26.3.

How does Zoe do against Syndra in the early game?

In the early game, Syndra has the advantage against Zoe with a 70.4% win rate versus 29.6%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Zoe do against Syndra in the late game?

In the late game, Syndra takes over the Zoe vs Syndra matchup with a 65.9% win rate compared to 34.1%. Syndra scales better into team fights and objective contests after 25 minutes.

Who wins the Zoe vs Syndra matchup?

Syndra wins the matchup against Zoe with a 67.6% win rate in League of Legends patch 26.3. The 35.2 percentage point advantage means Syndra is significantly favored in this lane matchup based on 71 games analyzed.

What is the best Zoe build against Syndra?

The best Zoe build against Syndra includes Luden's Echo, Shadowflame, Banshee's Veil with Spellslinger's Shoes. This build achieves a 66.7% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Zoe runes against Syndra?

The best Zoe runes against Syndra use the Domination primary tree with Sorcery secondary. This rune setup achieves a 42.9% win rate in the Zoe vs Syndra matchup. See the full rune breakdown in the matchup comparison above.

Does Zoe counter Syndra?

No, Zoe struggles against Syndra with only a 32.4% win rate. Syndra has the advantage in this matchup. Zoe players should focus on safe farming and avoiding extended trades to minimize Syndra's lead.

How do I play Zoe against Syndra?

When playing Zoe against Syndra, play cautiously and avoid Syndra's power spikes. Look for jungle assistance and team-dependent plays since Syndra has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.