Zoe - League of Legends Champion
Win Rate
51.3%
Pick Rate
1.8%

Zoevs Syndra

AMage
Patch26.7
Matches508,082
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 13, 2026
MethodologyData Methodology

Zoe vs Syndra is a decisive matchup in LoL patch 26.7. Zoe wins with a 62.1% win rate (+24.1%) over Syndra based on 29 games. Zoe holds the advantage in both the early and late game. Below you'll find the best Zoe build, runes, laning stats, and strategies for the Zoe vs Syndra matchup.

Zoe Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Zoe performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Syndra - 62.1% win rateSyndra(62.1%)
Zoe - 62.1% win rate in this matchup
Zoe
62.1% WR
VS
Syndra vs Zoe matchup - 37.9% win rate
Syndra
37.9% WR

Who Wins the Zoe vs Syndra Matchup?

Zoe wins the Zoe vs Syndra matchup
Winner
Zoe
Matches: 29
62.1%
Win Rate
37.9%
6.5
CS / min
6.9
918
DMG / min
802
11,990
Gold / game
12,048
98
Heal / min
65
341
DMG Mitigated / min
291
1.2
CC / min
1.2
58.3%
Early Game WR
41.7%
64.7%
Late Game WR
35.3%

Zoe vs Syndra Matchup Summary

The Zoe vs Syndra matchup is a decisive matchup in League of Legends ranked play. Based on 29 recent matches analyzed, Zoe wins with a 62.1% win rate compared to Syndra's 37.9%, giving Zoe a 24.1 percentage point advantage. Zoe dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Syndra players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Zoe leads by 83 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Zoe players can confidently pick into Syndra and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Syndra away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Zoe vs Syndra Laning Phase Breakdown

Zoe wins the laning phase against Syndra in League of Legends

Zoe is favored during the laning phase against Syndra, winning 3 out of 5 key stat categories. Zoe holds advantages in damage, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.5Zoe
6.9Syndra
Syndra edges out Zoe by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 6 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Syndra.
Damage
918Zoe
802Syndra
Zoe heavily out-damages Syndra by 116 DMG/min, dominating both short trades and all-in fights. Syndra should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Zoe's sustained damage advantage take over.
Economy
11,990Zoe
12,048Syndra
Zoe and Syndra generate nearly equal gold per game, with just a 57 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
1.2Zoe
1.2Syndra
Both Zoe and Syndra provide similar amounts of crowd control (0.0s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
439Zoe
356Syndra
Zoe heals and mitigates 83 more damage per minute than Syndra, providing moderate extra durability. This sustain edge allows Zoe to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Syndra.

Best Zoe Build Against Syndra

Spellslinger's Shoes is the optimal boots choice against Syndra, providing the mobility and stats Zoe needs most in this matchup. The top-performing core items for Zoe against Syndra are Luden's Echo, Shadowflame and Lich Bane. This combination gives Zoe an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 5 games — well above average and making it the top item path against Syndra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Zoe vs Syndra matchup.

Early Game vs Late Game

Early Game
Zoe
58.3%
+16.7% advantage
Zoe early game win rateZoe58.3%
Syndra early game win rateSyndra41.7%
Late Game
Zoe
64.7%
+29.4% advantage
Zoe late game win rateZoe64.7%
Syndra late game win rateSyndra35.3%

Zoe dominates the early game (first 15 minutes) with a commanding 58.3% win rate — a 16.7 percentage point lead over Syndra. This lopsided early game means Zoe can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Zoe is far superior in the late game (25+ minutes), boasting a 64.7% win rate — 29.4 points above Syndra. Extended games heavily favor Zoe, whose kit and scaling make them a dominant force in team fights and objective control.

Zoe holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Syndra players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Zoe Runes Against Syndra

Domination rune tree - Zoe primary runes vs SyndraDomination
Electrocute - best Zoe rune vs SyndraTaste of Blood - best Zoe rune vs SyndraGrisly Mementos - best Zoe rune vs SyndraRelentless Hunter - best Zoe rune vs Syndra
Sorcery rune tree - Zoe secondary runes vs SyndraSorcery
Nimbus Cloak - best Zoe rune vs SyndraScorch - best Zoe rune vs Syndra
80.0% WR

Running Domination primary with Sorcery secondary allows Zoe to press their advantage against Syndra, amplifying the strengths that make this a favorable matchup.


Zoe matchup data for League of Legends patch 26.7. The table below shows Zoe's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zoe build, runes, laning stats, and early vs late game analysis for that specific matchup.

Zoe matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
44.76%1056.088311,86338.0%50.9%
45.83%725.786211,52946.0%45.7%
45.31%646.279211,33034.4%56.3%
53.97%635.584810,58550.0%57.6%
63.46%525.892212,14360.0%65.6%
56.00%506.388711,56259.1%53.6%
40.00%505.281411,56237.5%41.2%
55.10%495.994511,50359.1%51.9%
42.55%474.379410,86318.8%54.8%
44.44%456.096511,85037.5%48.3%
60.00%405.992311,97271.4%53.9%
50.00%385.783311,63056.3%45.5%
51.35%376.290210,96842.1%61.1%
43.24%375.893611,49243.8%42.9%
50.00%345.898612,86545.5%52.2%
48.48%336.387410,32338.1%66.7%
51.52%335.889411,68861.1%40.0%
46.88%325.789811,12447.1%46.7%
50.00%325.989010,47652.6%46.1%
62.07%296.591811,99058.3%64.7%
62.07%296.294513,00463.6%61.1%
44.83%293.881310,72744.4%45.0%
30.77%265.486610,53055.6%17.6%
44.00%255.882010,45123.1%66.7%
36.00%256.295610,91050.0%26.7%
54.17%243.795310,32458.3%50.0%
45.83%245.588711,93350.0%43.8%
54.55%226.394512,25862.5%50.0%
54.55%226.187110,69455.6%53.9%
50.00%225.692711,85175.0%35.7%
42.86%215.691712,05950.0%40.0%
52.38%214.187311,83050.0%53.9%
52.38%216.297712,87266.7%46.7%
47.37%196.589812,10433.3%60.0%
31.58%191.37008,78730.0%33.3%
52.63%195.791611,86687.5%27.3%
50.00%182.181810,08855.6%44.4%
47.06%171.57149,35233.3%62.5%
41.18%171.48059,54157.1%30.0%
46.67%153.789412,48275.0%36.4%
57.14%146.787111,04454.5%66.7%
35.71%145.581710,95733.3%37.5%
69.23%137.01,08313,22075.0%60.0%
53.85%131.775310,60875.0%44.4%
61.54%131.67089,68383.3%42.9%
66.67%121.687111,22466.7%66.7%
75.00%124.890412,41675.0%75.0%
50.00%126.094311,92666.7%44.4%
41.67%126.28759,65525.0%75.0%
41.67%122.07199,62760.0%28.6%
63.64%111.67779,79783.3%40.0%
80.00%102.181911,386100.0%60.0%
60.00%105.786510,11550.0%75.0%
80.00%105.51,07211,159100.0%71.4%
55.56%92.784911,94750.0%57.1%
66.67%95.899612,035100.0%50.0%
55.56%91.37519,43860.0%50.0%
33.33%95.079512,25150.0%28.6%
66.67%91.68069,51080.0%50.0%
11.11%96.088910,03816.7%0.0%
62.50%81.57549,55150.0%100.0%
75.00%85.91,32513,267100.0%66.7%
37.50%81.777111,59933.3%40.0%
25.00%81.888610,68233.3%20.0%
50.00%81.475510,71025.0%75.0%
42.86%71.46266,35533.3%100.0%
42.86%75.191012,66375.0%0.0%
16.67%66.77199,85125.0%0.0%
50.00%65.81,00811,7100.0%100.0%
50.00%62.27239,85650.0%50.0%
100.00%66.879813,448100.0%100.0%
66.67%64.885310,36580.0%0.0%
100.00%51.663410,257100.0%100.0%
60.00%55.71,01412,48150.0%66.7%
20.00%56.26108,04420.0%0.0%
80.00%56.31,21111,720100.0%66.7%
60.00%55.689312,47266.7%50.0%
60.00%56.51,07013,251100.0%33.3%

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Zoe vs Syndra - Frequently Asked Questions

How does Zoe do against Syndra in League of Legends?

Zoe wins the Zoe vs Syndra matchup with a 62.1% win rate compared to Syndra's 37.9%, a 24.1 percentage point difference. This data is based on 29 recent ranked games in patch 26.7.

How does Zoe do against Syndra in the early game?

In the early game, Zoe has the advantage against Syndra with a 58.3% win rate versus 41.7%. Zoe players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Zoe do against Syndra in the late game?

In the late game, Zoe takes over the Zoe vs Syndra matchup with a 64.7% win rate compared to 35.3%. Zoe scales better into team fights and objective contests after 25 minutes.

Who wins the Zoe vs Syndra matchup?

Zoe wins the matchup against Syndra with a 62.1% win rate in League of Legends patch 26.7. The 24.1 percentage point advantage means Zoe is significantly favored in this lane matchup based on 29 games analyzed.

What is the best Zoe build against Syndra?

The best Zoe build against Syndra includes Luden's Echo, Shadowflame, Lich Bane with Spellslinger's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Zoe runes against Syndra?

The best Zoe runes against Syndra use the Domination primary tree with Sorcery secondary. This rune setup achieves a 80.0% win rate in the Zoe vs Syndra matchup. See the full rune breakdown in the matchup comparison above.

Does Zoe counter Syndra?

Yes, Zoe has a favorable matchup against Syndra with a 62.1% win rate. Zoe strongly counters Syndra in lane based on current patch 26.7 data.

How do I play Zoe against Syndra?

When playing Zoe against Syndra, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.