Vayne - League of Legends Champion
Win Rate
49.3%
Pick Rate
4.9%

Vaynevs Varus

CMarksmanAssassin
Patch26.14
Matches104,630
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 17, 2026
MethodologyData Methodology

Vayne vs Varus is a decisive matchup in LoL patch 26.14. Vayne wins with a 56.3% win rate (+12.5%) over Varus based on 16 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Varus matchup.

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Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 56.3% win rate in this matchup
Vayne
56.3% WR
VS
Varus vs Vayne matchup - 43.8% win rate
Varus
43.8% WR

Who Wins the Vayne vs Varus Matchup?

Vayne wins the Vayne vs Varus matchup
Winner
Vayne
Matches: 16
56.3%
Win Rate
43.8%
6.4
CS / min
6.7
896
DMG / min
902
12,698
Gold / game
12,300
231
Heal / min
160
599
DMG Mitigated / min
467
0.3
CC / min
0.9
50.0%
Early Game WR
50.0%
60.0%
Late Game WR
40.0%

Vayne vs Varus Matchup Summary

The Vayne vs Varus matchup is a decisive matchup in League of Legends ranked play. Based on 16 recent matches analyzed, Vayne wins with a 56.3% win rate compared to Varus's 43.8%, giving Vayne a 12.5 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Varus players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Varus leads by 0.5s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne players can confidently pick into Varus and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Varus away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Varus Laning Phase Breakdown

Varus wins the laning phase against Vayne in League of Legends

Varus is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Varus holds advantages in farming, damage and crowd control, making them the stronger laner in this matchup.

Farming
6.4Vayne
6.7Varus
Varus edges out Vayne by 0.3 CS per minute — a moderate farming advantage that adds up to roughly 5 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Varus.
Damage
896Vayne
902Varus
Damage output is virtually even between Vayne and Varus, with only 7 DMG/min separating them. Fights in this matchup are decided more by ability timing and positioning than raw damage numbers, making mechanical skill the deciding factor in trades.
Economy
12,698Vayne
12,300Varus
Vayne earns 397 more gold per game than Varus, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Vayne slightly faster item completions.
Utility
0.3Vayne
0.9Varus
Varus provides 0.5 seconds more crowd control per minute than Vayne, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Varus coordinate with their jungler and control the pace of skirmishes.
Sustain
829Vayne
627Varus
Vayne vastly out-sustains Varus, healing and mitigating 203 more damage per minute. This massive durability gap means Vayne can absorb significant punishment and remain in lane while Varus is forced to recall. Building grievous wounds early is essential for Varus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Varus

Berserker's Greaves is the optimal boots choice against Varus, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Varus are Essence Reaver, Stormrazor and Lord Dominik's Regards. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Varus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Varus matchup.

Early Game vs Late Game

Early Game
Vayne
50.0%
+0.0% advantage
Vayne early game win rateVayne50.0%
Varus early game win rateVarus50.0%
Late Game
Vayne
60.0%
+20.0% advantage
Vayne late game win rateVayne60.0%
Varus late game win rateVarus40.0%

The early game (first 15 minutes) is a toss-up between Vayne and Varus, with Vayne holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Vayne is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Varus. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Varus players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Vayne Runes Against Varus

Precision rune tree - Vayne primary runes vs VarusPrecision
Lethal Tempo - best Vayne rune vs VarusTriumph - best Vayne rune vs VarusLegend: Alacrity - best Vayne rune vs VarusCoup de Grace - best Vayne rune vs Varus
Resolve rune tree - Vayne secondary runes vs VarusResolve
Conditioning - best Vayne rune vs VarusOvergrowth - best Vayne rune vs Varus
50.0% WR

Running Precision primary with Resolve secondary allows Vayne to press their advantage against Varus, amplifying the strengths that make this a favorable matchup.


Vayne matchup data for League of Legends patch 26.14. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
46.38%695.784712,66650.0%44.4%
55.22%675.886913,28856.0%54.8%
48.44%646.284912,29851.7%45.7%
47.46%596.288813,98021.4%55.6%
48.94%476.584611,42746.1%52.4%
36.17%476.173912,4980.0%51.5%
51.35%376.395512,65426.7%68.2%
39.39%336.480513,36933.3%41.7%
40.74%276.391213,43050.0%36.8%
40.00%256.080510,88530.8%50.0%
44.00%256.184813,51520.0%50.0%
65.00%206.384211,31685.7%53.9%
40.00%205.973011,00430.0%50.0%
47.06%175.686512,15550.0%45.5%
56.25%166.489612,69850.0%60.0%
43.75%166.21,04014,05533.3%50.0%
25.00%165.57789,95011.1%42.9%
42.86%146.089314,23140.0%44.4%
57.14%146.084113,070100.0%40.0%
50.00%145.981111,94925.0%60.0%
53.85%136.01,02412,38950.0%57.1%
41.67%126.579613,05520.0%57.1%
50.00%126.41,09412,67640.0%57.1%
58.33%126.875711,52337.5%100.0%
66.67%126.679115,12433.3%77.8%
83.33%126.67898,66781.8%100.0%
72.73%115.290112,22675.0%71.4%
72.73%115.969612,05150.0%85.7%
40.00%107.076612,35520.0%60.0%
50.00%105.87309,02928.6%100.0%
40.00%105.375111,0470.0%66.7%
90.00%106.91,37814,629100.0%85.7%
33.33%95.91,09811,46025.0%40.0%
77.78%97.079010,74683.3%66.7%
44.44%96.990616,7150.0%50.0%
37.50%86.174213,4940.0%42.9%
42.86%76.695214,5050.0%60.0%
71.43%77.21,35616,04850.0%80.0%
71.43%76.11,00314,896100.0%66.7%
71.43%76.01,24813,755100.0%60.0%
42.86%76.483911,6500.0%60.0%
66.67%66.07727,10660.0%100.0%
33.33%66.290313,02450.0%25.0%
40.00%55.399213,924100.0%25.0%
40.00%56.01,05714,8920.0%50.0%
40.00%57.777012,413100.0%25.0%
80.00%56.999112,634100.0%75.0%
60.00%56.158411,67650.0%66.7%
60.00%52.79919,890100.0%0.0%

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Vayne vs Varus - Frequently Asked Questions

How does Vayne do against Varus in League of Legends?

Vayne wins the Vayne vs Varus matchup with a 56.3% win rate compared to Varus's 43.8%, a 12.5 percentage point difference. This data is based on 16 recent ranked games in patch 26.14.

How does Vayne do against Varus in the early game?

In the early game, Vayne has the advantage against Varus with a 50.0% win rate versus 50.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Varus in the late game?

In the late game, Vayne takes over the Vayne vs Varus matchup with a 60.0% win rate compared to 40.0%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Varus matchup?

Vayne wins the matchup against Varus with a 56.3% win rate in League of Legends patch 26.14. The 12.5 percentage point advantage means Vayne is significantly favored in this lane matchup based on 16 games analyzed.

What is the best Vayne build against Varus?

The best Vayne build against Varus includes Essence Reaver, Stormrazor, Lord Dominik's Regards with Berserker's Greaves. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Varus?

The best Vayne runes against Varus use the Precision primary tree with Resolve secondary. This rune setup achieves a 50.0% win rate in the Vayne vs Varus matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Varus?

Yes, Vayne has a favorable matchup against Varus with a 56.3% win rate. Vayne strongly counters Varus in lane based on current patch 26.14 data.

How do I play Vayne against Varus?

When playing Vayne against Varus, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.