Vayne - League of Legends Champion
Win Rate
47.9%
Pick Rate
4.8%

Vaynevs Mordekaiser

FMarksmanAssassin
Patch26.14
Matches134,440
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 20, 2026
MethodologyData Methodology

Vayne vs Mordekaiser is a decisive matchup in LoL patch 26.14. Vayne wins with a 59.1% win rate (+18.2%) over Mordekaiser based on 22 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Mordekaiser matchup.

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Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 59.1% win rate in this matchup
Vayne
59.1% WR
VS
Mordekaiser vs Vayne matchup - 40.9% win rate
Mordekaiser
40.9% WR

Who Wins the Vayne vs Mordekaiser Matchup?

Vayne wins the Vayne vs Mordekaiser matchup
Winner
Vayne
Matches: 22
59.1%
Win Rate
40.9%
6.2
CS / min
5.5
814
DMG / min
634
11,073
Gold / game
10,465
253
Heal / min
285
472
DMG Mitigated / min
1,205
0.3
CC / min
0.4
66.7%
Early Game WR
33.3%
53.9%
Late Game WR
46.1%

Vayne vs Mordekaiser Matchup Summary

The Vayne vs Mordekaiser matchup is a decisive matchup in League of Legends ranked play. Based on 22 recent matches analyzed, Vayne wins with a 59.1% win rate compared to Mordekaiser's 40.9%, giving Vayne a 18.2 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Mordekaiser players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Mordekaiser leads by 765 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne players can confidently pick into Mordekaiser and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Mordekaiser away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Mordekaiser Laning Phase Breakdown

Vayne wins the laning phase against Mordekaiser in League of Legends

Vayne is favored during the laning phase against Mordekaiser, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
6.2Vayne
5.5Mordekaiser
Vayne edges out Mordekaiser by 0.7 CS per minute — a moderate farming advantage that adds up to roughly 11 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Vayne.
Damage
814Vayne
634Mordekaiser
Vayne heavily out-damages Mordekaiser by 180 DMG/min, dominating both short trades and all-in fights. Mordekaiser should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
11,073Vayne
10,465Mordekaiser
Vayne earns 608 more gold per game than Mordekaiser, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Vayne slightly faster item completions.
Utility
0.3Vayne
0.4Mordekaiser
Both Vayne and Mordekaiser provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
725Vayne
1,490Mordekaiser
Mordekaiser vastly out-sustains Vayne, healing and mitigating 765 more damage per minute. This massive durability gap means Mordekaiser can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Mordekaiser

Berserker's Greaves is the optimal boots choice against Mordekaiser, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Mordekaiser are Blade of The Ruined King, Guinsoo's Rageblade and Experimental Hexplate. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Mordekaiser. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Mordekaiser matchup.

Early Game vs Late Game

Early Game
Vayne
66.7%
+33.3% advantage
Vayne early game win rateVayne66.7%
Mordekaiser early game win rateMordekaiser33.3%
Late Game
Vayne
53.9%
+7.7% advantage
Vayne late game win rateVayne53.9%
Mordekaiser late game win rateMordekaiser46.1%

Vayne dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Mordekaiser. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Vayne is far superior in the late game (25+ minutes), boasting a 53.9% win rate — 7.7 points above Mordekaiser. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Mordekaiser players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Vayne Runes Against Mordekaiser

Precision rune tree - Vayne primary runes vs MordekaiserPrecision
Lethal Tempo - best Vayne rune vs MordekaiserTriumph - best Vayne rune vs MordekaiserLegend: Alacrity - best Vayne rune vs MordekaiserCoup de Grace - best Vayne rune vs Mordekaiser
Resolve rune tree - Vayne secondary runes vs MordekaiserResolve
Conditioning - best Vayne rune vs MordekaiserOvergrowth - best Vayne rune vs Mordekaiser
63.6% WR

Running Precision primary with Resolve secondary allows Vayne to press their advantage against Mordekaiser, amplifying the strengths that make this a favorable matchup.


Vayne matchup data for League of Legends patch 26.14. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
48.39%935.883812,74245.2%50.0%
46.99%836.385412,66042.9%50.0%
53.01%835.987313,59358.1%50.0%
48.72%786.286213,82135.0%53.5%
46.77%626.382510,60241.7%53.9%
36.54%526.173912,14111.1%50.0%
51.02%496.494213,18130.0%65.5%
33.33%426.382113,28025.0%36.7%
51.61%316.181612,32450.0%52.4%
40.00%306.080211,18235.7%43.8%
40.00%306.388012,92944.4%38.1%
41.67%246.093713,41744.4%40.0%
43.48%235.970411,49130.0%53.9%
59.09%226.281411,07366.7%53.9%
50.00%205.790912,85257.1%46.1%
26.32%195.776910,39020.0%33.3%
57.89%196.390411,95150.0%63.6%
63.16%196.275310,65175.0%42.9%
61.11%185.888013,02580.0%53.9%
41.18%175.875611,40716.7%54.5%
66.67%155.581111,03883.3%55.6%
40.00%156.088714,12640.0%40.0%
42.86%146.375812,37728.6%57.1%
50.00%146.31,08313,08740.0%55.6%
50.00%146.671411,38233.3%80.0%
57.14%146.01,01611,73057.1%57.1%
46.15%136.880711,33428.6%66.7%
84.62%136.81,30913,21880.0%87.5%
38.46%135.87979,95022.2%75.0%
61.54%136.375715,01433.3%70.0%
33.33%126.589715,6330.0%40.0%
72.73%115.969612,05150.0%85.7%
40.00%106.082811,0040.0%57.1%
30.00%105.91,09210,36820.0%40.0%
40.00%105.375111,0470.0%66.7%
77.78%97.079010,74683.3%66.7%
66.67%96.11,02415,000100.0%62.5%
44.44%96.178013,51650.0%42.9%
37.50%86.594812,7660.0%60.0%
50.00%86.38268,12950.0%50.0%
71.43%76.01,24813,755100.0%60.0%
71.43%77.21,35616,04850.0%80.0%
66.67%66.785212,325100.0%50.0%
16.67%65.996912,6300.0%33.3%
66.67%65.765712,40550.0%75.0%
33.33%66.290313,02450.0%25.0%
50.00%66.583813,1700.0%75.0%
66.67%66.694911,83950.0%75.0%
50.00%66.097112,154100.0%40.0%
33.33%67.475312,492100.0%20.0%
66.67%63.61,00510,165100.0%0.0%
33.33%65.772612,8680.0%40.0%
50.00%66.41,18513,5870.0%60.0%
40.00%56.083912,463100.0%25.0%
40.00%56.01,05714,8920.0%50.0%
40.00%55.974410,886100.0%25.0%
40.00%55.399213,924100.0%25.0%
40.00%55.71,01014,069100.0%25.0%

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Vayne vs Mordekaiser - Frequently Asked Questions

How does Vayne do against Mordekaiser in League of Legends?

Vayne wins the Vayne vs Mordekaiser matchup with a 59.1% win rate compared to Mordekaiser's 40.9%, a 18.2 percentage point difference. This data is based on 22 recent ranked games in patch 26.14.

How does Vayne do against Mordekaiser in the early game?

In the early game, Vayne has the advantage against Mordekaiser with a 66.7% win rate versus 33.3%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Mordekaiser in the late game?

In the late game, Vayne takes over the Vayne vs Mordekaiser matchup with a 53.9% win rate compared to 46.1%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Mordekaiser matchup?

Vayne wins the matchup against Mordekaiser with a 59.1% win rate in League of Legends patch 26.14. The 18.2 percentage point advantage means Vayne is significantly favored in this lane matchup based on 22 games analyzed.

What is the best Vayne build against Mordekaiser?

The best Vayne build against Mordekaiser includes Blade of The Ruined King, Guinsoo's Rageblade, Experimental Hexplate with Berserker's Greaves. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Mordekaiser?

The best Vayne runes against Mordekaiser use the Precision primary tree with Resolve secondary. This rune setup achieves a 63.6% win rate in the Vayne vs Mordekaiser matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Mordekaiser?

Yes, Vayne has a favorable matchup against Mordekaiser with a 59.1% win rate. Vayne strongly counters Mordekaiser in lane based on current patch 26.14 data.

How do I play Vayne against Mordekaiser?

When playing Vayne against Mordekaiser, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.