Zedvs Vayne
Zed vs Vayne is a very close matchup in LoL patch 26.4. Zed wins with a 50.0% win rate (+0.0%) over Vayne based on 12 games. Zed wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Zed build, runes, laning stats, and strategies for the Zed vs Vayne matchup.
Zed Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Zed performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Vayne(50.0%)Who Wins the Zed vs Vayne Matchup?
Zed vs Vayne Matchup Summary
The Zed vs Vayne matchup is essentially a coin-flip matchup in League of Legends ranked play. Based on 12 recent matches analyzed, Zed wins with a 50.0% win rate compared to Vayne's 50.0%, giving Zed a 0.0 percentage point advantage. Game phase dynamics play a critical role here: Zed controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Zed needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Vayne leads by 0.1s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Zed has a statistical edge, but the margin is close enough that respecting Vayne's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Zed vs Vayne Laning Phase Breakdown
Vayne is favored during the laning phase against Zed, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.
Best Zed Build Against Vayne
Ionian Boots of Lucidity is the optimal boots choice against Vayne, providing the mobility and stats Zed needs most in this matchup. The top-performing core items for Zed against Vayne are Voltaic Cyclosword, Axiom Arc and Serylda's Grudge. This combination gives Zed an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 75.0% win rate across 4 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Zed vs Vayne matchup.
Early Game vs Late Game
Zed66.7%Vayne33.3%Zed44.4%Vayne55.6%Zed dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Vayne. This lopsided early game means Zed can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Vayne is far superior in the late game (25+ minutes), boasting a 55.6% win rate — 11.1 points above Zed. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Zed must aggressively press their early advantage and close out the game before Vayne reaches their scaling breakpoints. If Vayne survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Zed Runes Against Vayne
Domination
Precision
The Domination primary with Precision secondary combination helps Zed maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Vayne.
Zed matchup data for League of Legends patch 26.4. The table below shows Zed's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zed build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 49.88% | 433 | 6.4 | 913 | 13,209 | 53.6% | 47.8% | |
| 45.18% | 364 | 6.5 | 899 | 12,724 | 38.6% | 50.5% | |
| 51.48% | 238 | 6.5 | 880 | 13,750 | 50.5% | 52.0% | |
| 49.01% | 205 | 6.5 | 968 | 12,704 | 56.2% | 43.4% | |
| 58.13% | 204 | 6.6 | 1,025 | 12,891 | 55.8% | 60.2% | |
| 48.21% | 195 | 6.2 | 923 | 12,897 | 38.9% | 53.7% | |
| 53.55% | 184 | 5.8 | 874 | 12,972 | 51.8% | 55.0% | |
| 38.99% | 160 | 5.9 | 946 | 12,607 | 38.8% | 39.2% | |
| 49.69% | 160 | 6.3 | 846 | 12,447 | 47.8% | 51.1% | |
| 50.00% | 158 | 6.4 | 984 | 12,740 | 46.7% | 53.0% | |
| 53.25% | 157 | 5.5 | 840 | 12,691 | 51.4% | 54.8% | |
| 56.58% | 154 | 6.1 | 843 | 13,378 | 49.1% | 61.0% | |
| 44.59% | 150 | 5.6 | 925 | 12,810 | 46.8% | 43.0% | |
| 48.89% | 135 | 5.9 | 770 | 12,083 | 47.8% | 50.0% | |
| 46.46% | 129 | 6.2 | 890 | 13,076 | 44.4% | 47.6% | |
| 50.79% | 127 | 6.8 | 912 | 12,572 | 47.8% | 54.2% | |
| 60.18% | 115 | 6.5 | 1,012 | 13,619 | 68.9% | 54.4% | |
| 41.23% | 115 | 6.4 | 897 | 13,418 | 39.2% | 42.9% | |
| 50.89% | 112 | 6.0 | 870 | 12,836 | 52.4% | 50.0% | |
| 48.08% | 105 | 5.9 | 913 | 13,057 | 55.0% | 43.8% | |
| 47.00% | 100 | 6.5 | 827 | 12,167 | 45.0% | 48.3% | |
| 56.25% | 97 | 6.4 | 890 | 13,086 | 63.4% | 50.9% | |
| 45.05% | 92 | 6.2 | 835 | 12,305 | 44.7% | 45.3% | |
| 47.73% | 91 | 6.4 | 871 | 13,300 | 54.0% | 43.1% | |
| 54.95% | 91 | 6.6 | 970 | 13,100 | 58.5% | 52.0% | |
| 44.44% | 90 | 6.6 | 884 | 13,025 | 36.8% | 50.0% | |
| 56.82% | 89 | 6.0 | 863 | 12,783 | 61.5% | 53.1% | |
| 51.72% | 87 | 6.5 | 892 | 13,042 | 53.3% | 50.9% | |
| 50.00% | 86 | 6.0 | 861 | 12,502 | 52.6% | 47.9% | |
| 47.62% | 85 | 6.6 | 987 | 11,941 | 46.7% | 48.7% | |
| 50.60% | 83 | 5.2 | 908 | 13,488 | 52.5% | 48.8% | |
| 50.62% | 82 | 6.8 | 1,042 | 12,461 | 62.5% | 39.0% | |
| 44.30% | 79 | 6.6 | 936 | 13,005 | 48.6% | 40.9% | |
| 52.17% | 70 | 6.6 | 1,046 | 13,597 | 65.5% | 42.5% | |
| 44.93% | 69 | 6.4 | 1,024 | 13,202 | 54.2% | 40.0% | |
| 43.08% | 65 | 6.4 | 928 | 12,556 | 36.4% | 46.5% | |
| 46.15% | 65 | 6.6 | 1,102 | 13,642 | 48.4% | 44.1% | |
| 57.14% | 63 | 6.2 | 868 | 12,739 | 55.3% | 60.0% | |
| 50.85% | 60 | 5.9 | 960 | 13,906 | 47.6% | 52.6% | |
| 46.15% | 52 | 5.9 | 804 | 13,023 | 41.7% | 50.0% | |
| 60.00% | 51 | 6.2 | 925 | 13,285 | 52.2% | 66.7% | |
| 52.94% | 51 | 1.7 | 807 | 14,372 | 52.4% | 53.3% | |
| 52.08% | 49 | 2.4 | 961 | 14,514 | 38.9% | 60.0% | |
| 50.00% | 46 | 6.0 | 1,086 | 13,213 | 30.0% | 65.4% | |
| 60.87% | 46 | 5.1 | 829 | 12,649 | 60.0% | 61.5% | |
| 37.78% | 45 | 1.3 | 873 | 14,628 | 37.5% | 37.9% | |
| 46.34% | 41 | 6.9 | 944 | 13,139 | 38.5% | 50.0% | |
| 45.00% | 40 | 2.5 | 850 | 14,930 | 66.7% | 32.0% | |
| 51.28% | 39 | 5.6 | 957 | 13,300 | 46.7% | 54.2% | |
| 43.59% | 39 | 6.0 | 1,012 | 12,928 | 50.0% | 40.0% | |
| 43.59% | 39 | 2.1 | 830 | 13,996 | 50.0% | 38.1% | |
| 57.89% | 38 | 6.2 | 890 | 12,887 | 64.7% | 52.4% | |
| 54.05% | 37 | 6.4 | 979 | 12,318 | 44.4% | 63.2% | |
| 55.56% | 36 | 3.1 | 927 | 13,056 | 55.0% | 56.3% | |
| 66.67% | 36 | 3.0 | 877 | 13,807 | 53.3% | 76.2% | |
| 47.22% | 36 | 3.8 | 1,089 | 13,413 | 50.0% | 44.4% | |
| 47.06% | 34 | 6.6 | 1,004 | 14,033 | 60.0% | 36.8% | |
| 63.64% | 33 | 5.6 | 880 | 11,960 | 66.7% | 61.1% | |
| 22.58% | 32 | 1.5 | 880 | 13,974 | 37.5% | 6.7% | |
| 50.00% | 30 | 2.6 | 900 | 13,705 | 68.8% | 28.6% | |
| 41.38% | 29 | 4.4 | 923 | 14,397 | 60.0% | 31.6% | |
| 58.62% | 29 | 5.7 | 1,008 | 14,130 | 36.4% | 72.2% | |
| 53.57% | 28 | 1.8 | 750 | 13,813 | 54.5% | 52.9% | |
| 53.57% | 28 | 2.9 | 921 | 15,297 | 75.0% | 45.0% | |
| 44.44% | 27 | 1.8 | 834 | 13,137 | 23.1% | 64.3% | |
| 55.56% | 27 | 2.0 | 916 | 15,714 | 30.0% | 70.6% | |
| 62.96% | 27 | 4.4 | 865 | 14,635 | 71.4% | 60.0% | |
| 50.00% | 26 | 6.8 | 1,058 | 14,030 | 36.4% | 60.0% | |
| 48.00% | 25 | 6.6 | 897 | 12,329 | 46.1% | 50.0% | |
| 37.50% | 24 | 3.9 | 953 | 13,942 | 25.0% | 43.8% | |
| 62.50% | 24 | 4.1 | 943 | 13,594 | 70.0% | 57.1% | |
| 41.67% | 24 | 2.3 | 854 | 14,133 | 50.0% | 35.7% | |
| 58.33% | 24 | 3.2 | 922 | 13,094 | 64.3% | 50.0% | |
| 73.91% | 23 | 6.4 | 1,022 | 12,667 | 90.9% | 58.3% | |
| 56.52% | 23 | 6.4 | 940 | 12,944 | 87.5% | 40.0% | |
| 21.74% | 23 | 1.4 | 764 | 14,252 | 12.5% | 26.7% | |
| 45.45% | 23 | 5.6 | 851 | 14,071 | 16.7% | 56.3% | |
| 47.83% | 23 | 2.6 | 891 | 13,139 | 38.5% | 60.0% | |
| 68.18% | 22 | 6.0 | 1,145 | 15,949 | 66.7% | 68.8% | |
| 22.73% | 22 | 1.5 | 838 | 14,692 | 11.1% | 30.8% | |
| 52.38% | 22 | 1.8 | 847 | 13,816 | 50.0% | 54.5% | |
| 38.10% | 21 | 6.0 | 953 | 12,607 | 12.5% | 53.9% | |
| 60.00% | 20 | 1.8 | 923 | 16,415 | 60.0% | 60.0% | |
| 50.00% | 20 | 6.4 | 869 | 11,811 | 58.3% | 37.5% | |
| 57.89% | 19 | 1.6 | 957 | 15,177 | 44.4% | 70.0% | |
| 55.56% | 18 | 6.5 | 995 | 13,220 | 88.9% | 22.2% | |
| 43.75% | 17 | 2.7 | 830 | 16,418 | 60.0% | 36.4% | |
| 35.29% | 17 | 3.3 | 926 | 14,383 | 20.0% | 41.7% | |
| 58.82% | 17 | 2.2 | 938 | 16,442 | 66.7% | 57.1% | |
| 37.50% | 16 | 6.8 | 833 | 12,714 | 37.5% | 37.5% | |
| 43.75% | 16 | 5.9 | 929 | 13,327 | 40.0% | 45.5% | |
| 50.00% | 16 | 1.4 | 935 | 14,944 | 80.0% | 36.4% | |
| 43.75% | 16 | 6.5 | 913 | 12,795 | 57.1% | 33.3% | |
| 31.25% | 16 | 6.1 | 854 | 11,752 | 37.5% | 25.0% | |
| 43.75% | 16 | 1.6 | 734 | 12,789 | 50.0% | 40.0% | |
| 73.33% | 15 | 3.1 | 1,002 | 15,731 | 50.0% | 81.8% | |
| 42.86% | 15 | 6.0 | 870 | 11,919 | 33.3% | 50.0% | |
| 46.67% | 15 | 7.0 | 898 | 12,593 | 50.0% | 42.9% | |
| 53.33% | 15 | 6.3 | 964 | 15,229 | 75.0% | 45.5% | |
| 57.14% | 14 | 6.2 | 1,023 | 15,660 | 100.0% | 45.5% | |
| 46.15% | 13 | 6.4 | 828 | 8,617 | 62.5% | 20.0% | |
| 30.77% | 13 | 3.1 | 820 | 12,402 | 14.3% | 50.0% | |
| 53.85% | 13 | 1.7 | 920 | 14,421 | 57.1% | 50.0% | |
| 46.15% | 13 | 4.3 | 939 | 13,235 | 50.0% | 42.9% | |
| 69.23% | 13 | 2.5 | 1,063 | 13,775 | 75.0% | 66.7% | |
| 16.67% | 12 | 3.0 | 880 | 14,217 | 25.0% | 12.5% | |
| 50.00% | 12 | 5.5 | 1,085 | 16,243 | 66.7% | 44.4% | |
| 58.33% | 12 | 7.3 | 1,159 | 15,613 | 25.0% | 75.0% | |
| 58.33% | 12 | 5.7 | 984 | 12,293 | 60.0% | 57.1% | |
| 18.18% | 11 | 4.3 | 744 | 11,530 | 0.0% | 40.0% | |
| 54.55% | 11 | 5.8 | 952 | 12,767 | 50.0% | 60.0% | |
| 54.55% | 11 | 4.1 | 868 | 12,501 | 71.4% | 25.0% | |
| 63.64% | 11 | 1.3 | 764 | 15,236 | 60.0% | 66.7% | |
| 36.36% | 11 | 2.0 | 855 | 14,805 | 60.0% | 16.7% | |
| 60.00% | 10 | 3.1 | 976 | 15,282 | 66.7% | 57.1% | |
| 40.00% | 10 | 1.1 | 661 | 12,272 | 42.9% | 33.3% | |
| 60.00% | 10 | 5.0 | 800 | 12,096 | 100.0% | 33.3% | |
| 40.00% | 10 | 3.3 | 968 | 15,210 | 50.0% | 33.3% | |
| 70.00% | 10 | 6.1 | 861 | 12,372 | 100.0% | 40.0% | |
| 40.00% | 10 | 6.1 | 1,033 | 12,887 | 25.0% | 50.0% | |
| 77.78% | 9 | 4.7 | 1,070 | 14,712 | 75.0% | 80.0% | |
| 44.44% | 9 | 5.1 | 805 | 14,587 | 100.0% | 28.6% | |
| 62.50% | 8 | 5.7 | 817 | 12,606 | 66.7% | 50.0% | |
| 12.50% | 8 | 5.5 | 733 | 13,777 | 0.0% | 16.7% | |
| 62.50% | 8 | 7.1 | 904 | 11,508 | 25.0% | 100.0% | |
| 71.43% | 7 | 4.8 | 841 | 12,858 | 66.7% | 75.0% | |
| 28.57% | 7 | 2.0 | 836 | 15,527 | 0.0% | 33.3% | |
| 28.57% | 7 | 6.5 | 1,048 | 13,244 | 0.0% | 50.0% | |
| 57.14% | 7 | 7.3 | 828 | 11,323 | 60.0% | 50.0% | |
| 16.67% | 6 | 7.2 | 893 | 14,288 | 0.0% | 50.0% | |
| 16.67% | 6 | 2.6 | 949 | 15,136 | 0.0% | 20.0% | |
| 50.00% | 6 | 6.0 | 753 | 12,676 | 33.3% | 66.7% | |
| 16.67% | 6 | 4.9 | 700 | 13,658 | 0.0% | 20.0% | |
| 60.00% | 5 | 6.5 | 1,168 | 14,921 | 100.0% | 33.3% | |
| 60.00% | 5 | 2.4 | 889 | 13,372 | 33.3% | 100.0% | |
| 60.00% | 5 | 6.1 | 829 | 12,751 | 100.0% | 33.3% | |
| 60.00% | 5 | 3.5 | 803 | 11,043 | 50.0% | 66.7% | |
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Zed vs Vayne - Frequently Asked Questions
How does Zed do against Vayne in League of Legends?
Zed wins the Zed vs Vayne matchup with a 50.0% win rate compared to Vayne's 50.0%, a 0.0 percentage point difference. This data is based on 12 recent ranked games in patch 26.4.
How does Zed do against Vayne in the early game?
In the early game, Zed has the advantage against Vayne with a 66.7% win rate versus 33.3%. Zed players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Zed do against Vayne in the late game?
In the late game, Vayne takes over the Zed vs Vayne matchup with a 55.6% win rate compared to 44.4%. Vayne scales better into team fights and objective contests after 25 minutes.
Who wins the Zed vs Vayne matchup?
Zed wins the matchup against Vayne with a 50.0% win rate in League of Legends patch 26.4. The 0.0 percentage point advantage means Zed is slightly favored in this lane matchup based on 12 games analyzed.
What is the best Zed build against Vayne?
The best Zed build against Vayne includes Voltaic Cyclosword, Axiom Arc, Serylda's Grudge with Ionian Boots of Lucidity. This build achieves a 75.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Zed runes against Vayne?
The best Zed runes against Vayne use the Domination primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Zed vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Zed counter Vayne?
Yes, Zed has a favorable matchup against Vayne with a 50.0% win rate. Zed slightly edges out Vayne in lane based on current patch 26.4 data.
How do I play Zed against Vayne?
When playing Zed against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.