Zedvs Vayne
Zed vs Vayne is a decisive matchup in LoL patch 26.10. Vayne wins with a 52.9% win rate (+5.9%) over Zed based on 17 games. Zed wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Zed build, runes, laning stats, and strategies for the Zed vs Vayne matchup.
Zed Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Zed performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Zed vs Vayne Matchup?
Zed vs Vayne Matchup Summary
The Zed vs Vayne matchup is a moderate matchup in League of Legends ranked play. Based on 17 recent matches analyzed, Vayne wins with a 52.9% win rate compared to Zed's 47.1%, giving Vayne a 5.9 percentage point advantage. Game phase dynamics play a critical role here: Zed controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Zed needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Vayne leads by 0.1s CC/min — a difference that heavily influences the outcome of trades and skirmishes. While Vayne is slightly favored, Zed can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Vayne's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Zed vs Vayne Laning Phase Breakdown
Zed is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Zed holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Best Zed Build Against Vayne
Crimson Lucidity is the optimal boots choice against Vayne, providing the mobility and stats Zed needs most in this matchup. The top-performing core items for Zed against Vayne are Voltaic Cyclosword, Axiom Arc and Serpent's Fang. This combination gives Zed an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 2 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Zed vs Vayne matchup.
Early Game vs Late Game
Zed50.0%
Vayne50.0%Zed40.0%Vayne60.0%The early game (first 15 minutes) is a toss-up between Zed and Vayne, with Zed holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.
Vayne is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Zed. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.
The power dynamics shift as the game progresses — Zed has the edge early, but Vayne gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.
Best Zed Runes Against Vayne
Inspiration
Resolve
The Inspiration and Resolve rune setup gives Zed the best tools to compete against Vayne in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Zed matchup data for League of Legends patch 26.10. The table below shows Zed's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zed build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 48.78% | 328 | 6.3 | 869 | 12,865 | 53.1% | 46.0% | |
| 52.91% | 327 | 6.4 | 991 | 13,316 | 52.6% | 53.1% | |
| 46.33% | 313 | 6.2 | 915 | 12,738 | 40.6% | 50.9% | |
| 47.81% | 297 | 6.1 | 969 | 12,616 | 46.3% | 48.9% | |
| 48.52% | 237 | 5.8 | 943 | 12,802 | 44.1% | 51.9% | |
| 51.72% | 203 | 6.1 | 986 | 13,278 | 59.3% | 46.7% | |
| 42.79% | 201 | 6.3 | 942 | 12,483 | 42.3% | 43.3% | |
| 58.38% | 197 | 6.2 | 1,084 | 13,748 | 63.1% | 54.9% | |
| 47.92% | 192 | 6.0 | 905 | 12,853 | 44.9% | 50.0% | |
| 52.43% | 185 | 6.3 | 928 | 12,678 | 61.7% | 45.2% | |
| 46.99% | 183 | 5.7 | 912 | 12,537 | 43.3% | 50.5% | |
| 49.42% | 172 | 5.6 | 1,010 | 13,339 | 51.5% | 48.1% | |
| 46.54% | 159 | 6.4 | 972 | 12,621 | 44.7% | 48.2% | |
| 52.23% | 157 | 5.9 | 996 | 13,417 | 54.7% | 50.5% | |
| 47.97% | 148 | 5.8 | 825 | 12,619 | 42.9% | 51.8% | |
| 48.30% | 147 | 6.0 | 951 | 13,186 | 38.5% | 53.7% | |
| 50.36% | 139 | 6.1 | 1,078 | 12,465 | 55.9% | 45.1% | |
| 42.34% | 137 | 6.0 | 930 | 13,135 | 38.3% | 45.5% | |
| 59.20% | 125 | 5.3 | 966 | 13,178 | 52.1% | 63.6% | |
| 42.20% | 109 | 4.8 | 961 | 12,751 | 46.0% | 39.0% | |
| 50.46% | 109 | 6.5 | 1,072 | 14,317 | 37.1% | 56.8% | |
| 52.78% | 108 | 5.9 | 898 | 12,679 | 55.0% | 51.5% | |
| 55.66% | 106 | 6.3 | 1,002 | 12,362 | 41.2% | 69.1% | |
| 58.59% | 99 | 5.8 | 914 | 12,463 | 68.4% | 52.5% | |
| 52.58% | 97 | 6.2 | 1,002 | 13,085 | 65.8% | 42.9% | |
| 46.88% | 96 | 5.4 | 912 | 12,932 | 57.1% | 36.2% | |
| 48.35% | 91 | 6.2 | 983 | 12,978 | 48.6% | 48.2% | |
| 52.75% | 91 | 5.7 | 981 | 13,029 | 61.0% | 46.0% | |
| 51.14% | 88 | 6.0 | 881 | 12,926 | 52.8% | 50.0% | |
| 54.55% | 88 | 6.2 | 969 | 12,651 | 48.8% | 59.6% | |
| 45.12% | 82 | 6.0 | 865 | 12,181 | 55.6% | 37.0% | |
| 38.16% | 76 | 6.4 | 1,018 | 12,844 | 48.4% | 31.1% | |
| 53.42% | 74 | 6.4 | 1,067 | 14,031 | 60.7% | 48.9% | |
| 56.16% | 73 | 6.4 | 1,060 | 12,162 | 54.8% | 58.1% | |
| 47.22% | 72 | 6.1 | 933 | 12,638 | 53.3% | 42.9% | |
| 52.86% | 70 | 6.0 | 962 | 13,377 | 56.7% | 50.0% | |
| 35.82% | 67 | 6.4 | 934 | 12,547 | 40.6% | 31.4% | |
| 42.19% | 64 | 1.3 | 919 | 14,993 | 50.0% | 36.8% | |
| 63.49% | 63 | 5.9 | 964 | 13,071 | 60.0% | 65.8% | |
| 49.18% | 61 | 1.6 | 958 | 14,290 | 50.0% | 48.8% | |
| 50.00% | 58 | 5.3 | 975 | 13,283 | 36.4% | 58.3% | |
| 48.28% | 58 | 1.3 | 754 | 12,846 | 43.3% | 53.6% | |
| 42.00% | 50 | 2.8 | 946 | 14,680 | 28.6% | 47.2% | |
| 50.00% | 50 | 5.5 | 1,076 | 13,020 | 52.6% | 48.4% | |
| 42.86% | 49 | 1.4 | 916 | 14,015 | 26.3% | 53.3% | |
| 39.58% | 48 | 6.2 | 1,169 | 13,276 | 43.8% | 37.5% | |
| 41.67% | 48 | 2.1 | 863 | 12,953 | 40.7% | 42.9% | |
| 44.68% | 47 | 2.0 | 865 | 12,446 | 47.6% | 42.3% | |
| 60.00% | 45 | 6.4 | 1,079 | 12,406 | 68.4% | 53.9% | |
| 54.76% | 42 | 1.9 | 931 | 14,421 | 55.6% | 54.2% | |
| 50.00% | 42 | 6.5 | 945 | 13,327 | 61.1% | 41.7% | |
| 35.00% | 40 | 1.6 | 904 | 14,350 | 25.0% | 39.3% | |
| 45.00% | 40 | 5.8 | 910 | 12,843 | 35.7% | 50.0% | |
| 39.47% | 38 | 6.1 | 901 | 12,150 | 33.3% | 43.5% | |
| 57.89% | 38 | 1.9 | 817 | 13,060 | 40.0% | 69.6% | |
| 51.35% | 37 | 5.4 | 1,011 | 13,681 | 50.0% | 52.0% | |
| 48.57% | 35 | 6.4 | 1,064 | 12,491 | 57.9% | 37.5% | |
| 48.48% | 33 | 6.3 | 868 | 12,912 | 58.3% | 42.9% | |
| 70.97% | 31 | 5.7 | 1,047 | 14,891 | 83.3% | 63.2% | |
| 56.67% | 30 | 5.9 | 1,063 | 14,001 | 54.5% | 57.9% | |
| 56.67% | 30 | 6.1 | 1,078 | 14,302 | 62.5% | 54.5% | |
| 56.67% | 30 | 1.0 | 722 | 13,416 | 61.5% | 52.9% | |
| 46.67% | 30 | 6.6 | 986 | 12,447 | 28.6% | 62.5% | |
| 37.93% | 29 | 5.8 | 971 | 13,700 | 50.0% | 31.6% | |
| 55.17% | 29 | 1.0 | 771 | 13,621 | 54.5% | 55.6% | |
| 32.14% | 28 | 5.9 | 926 | 12,228 | 16.7% | 43.8% | |
| 70.37% | 27 | 6.8 | 1,142 | 14,298 | 73.3% | 66.7% | |
| 37.04% | 27 | 6.2 | 942 | 12,326 | 38.5% | 35.7% | |
| 33.33% | 27 | 6.3 | 1,097 | 11,733 | 21.4% | 46.1% | |
| 53.85% | 26 | 6.2 | 1,096 | 14,833 | 42.9% | 57.9% | |
| 52.00% | 25 | 3.1 | 905 | 12,580 | 41.7% | 61.5% | |
| 56.00% | 25 | 4.4 | 1,079 | 13,641 | 37.5% | 64.7% | |
| 45.83% | 24 | 5.8 | 843 | 11,927 | 58.3% | 33.3% | |
| 54.17% | 24 | 5.5 | 1,105 | 11,851 | 33.3% | 75.0% | |
| 52.17% | 23 | 6.3 | 1,015 | 12,518 | 58.3% | 45.5% | |
| 54.55% | 22 | 4.4 | 804 | 11,315 | 50.0% | 60.0% | |
| 61.90% | 21 | 3.2 | 1,036 | 13,952 | 55.6% | 66.7% | |
| 33.33% | 21 | 4.7 | 929 | 12,462 | 27.3% | 40.0% | |
| 38.10% | 21 | 1.5 | 798 | 14,881 | 50.0% | 30.8% | |
| 38.10% | 21 | 1.6 | 981 | 15,928 | 33.3% | 40.0% | |
| 47.62% | 21 | 1.8 | 837 | 12,990 | 50.0% | 45.5% | |
| 42.86% | 21 | 3.2 | 1,062 | 16,433 | 33.3% | 46.7% | |
| 20.00% | 20 | 2.5 | 727 | 10,989 | 44.4% | 0.0% | |
| 35.00% | 20 | 5.3 | 948 | 13,906 | 25.0% | 41.7% | |
| 52.63% | 19 | 5.0 | 880 | 11,646 | 62.5% | 45.5% | |
| 44.44% | 18 | 5.0 | 967 | 12,010 | 14.3% | 63.6% | |
| 66.67% | 18 | 4.1 | 948 | 13,079 | 75.0% | 60.0% | |
| 41.18% | 17 | 3.9 | 921 | 14,624 | 28.6% | 50.0% | |
| 41.18% | 17 | 1.1 | 910 | 16,044 | 60.0% | 33.3% | |
| 47.06% | 17 | 5.4 | 747 | 11,313 | 50.0% | 40.0% | |
| 41.18% | 17 | 3.6 | 963 | 12,943 | 44.4% | 37.5% | |
| 35.29% | 17 | 6.5 | 1,064 | 14,653 | 50.0% | 30.8% | |
| 52.94% | 17 | 3.1 | 875 | 12,396 | 42.9% | 60.0% | |
| 47.06% | 17 | 6.0 | 1,110 | 13,773 | 42.9% | 50.0% | |
| 50.00% | 16 | 1.3 | 807 | 13,260 | 57.1% | 44.4% | |
| 37.50% | 16 | 6.3 | 1,092 | 14,289 | 25.0% | 50.0% | |
| 56.25% | 16 | 5.2 | 881 | 11,192 | 83.3% | 40.0% | |
| 43.75% | 16 | 6.2 | 950 | 12,570 | 14.3% | 66.7% | |
| 46.67% | 15 | 1.4 | 859 | 15,352 | 20.0% | 60.0% | |
| 40.00% | 15 | 5.1 | 831 | 11,992 | 50.0% | 33.3% | |
| 60.00% | 15 | 5.7 | 1,124 | 14,862 | 40.0% | 70.0% | |
| 50.00% | 14 | 6.3 | 1,088 | 13,684 | 71.4% | 28.6% | |
| 35.71% | 14 | 1.7 | 923 | 14,587 | 50.0% | 33.3% | |
| 53.85% | 13 | 6.3 | 920 | 12,682 | 75.0% | 44.4% | |
| 58.33% | 12 | 5.7 | 1,118 | 14,826 | 66.7% | 55.6% | |
| 33.33% | 12 | 2.0 | 826 | 13,254 | 50.0% | 25.0% | |
| 50.00% | 12 | 4.8 | 1,411 | 15,215 | 66.7% | 44.4% | |
| 18.18% | 11 | 6.2 | 917 | 11,188 | 14.3% | 25.0% | |
| 54.55% | 11 | 5.4 | 927 | 14,134 | 66.7% | 50.0% | |
| 81.82% | 11 | 3.2 | 821 | 12,286 | 75.0% | 85.7% | |
| 40.00% | 10 | 5.8 | 1,039 | 12,529 | 42.9% | 33.3% | |
| 50.00% | 10 | 6.4 | 899 | 11,849 | 50.0% | 50.0% | |
| 50.00% | 10 | 4.7 | 950 | 11,456 | 57.1% | 33.3% | |
| 50.00% | 10 | 5.5 | 1,004 | 14,504 | 75.0% | 33.3% | |
| 50.00% | 10 | 2.4 | 718 | 11,686 | 66.7% | 25.0% | |
| 30.00% | 10 | 5.4 | 1,147 | 9,410 | 33.3% | 25.0% | |
| 66.67% | 9 | 5.9 | 970 | 13,136 | 40.0% | 100.0% | |
| 44.44% | 9 | 2.7 | 994 | 15,028 | 0.0% | 57.1% | |
| 66.67% | 9 | 1.0 | 912 | 13,819 | 75.0% | 60.0% | |
| 62.50% | 8 | 5.1 | 1,388 | 16,894 | 100.0% | 50.0% | |
| 37.50% | 8 | 2.3 | 1,044 | 16,001 | 50.0% | 33.3% | |
| 37.50% | 8 | 5.6 | 1,258 | 15,868 | 0.0% | 50.0% | |
| 37.50% | 8 | 6.8 | 1,252 | 16,491 | 33.3% | 40.0% | |
| 62.50% | 8 | 1.8 | 744 | 13,048 | 80.0% | 33.3% | |
| 28.57% | 7 | 5.6 | 758 | 10,907 | 33.3% | 25.0% | |
| 57.14% | 7 | 5.6 | 961 | 12,001 | 50.0% | 60.0% | |
| 28.57% | 7 | 3.5 | 747 | 13,303 | 100.0% | 16.7% | |
| 71.43% | 7 | 6.8 | 836 | 10,771 | 50.0% | 100.0% | |
| 42.86% | 7 | 5.7 | 1,019 | 15,205 | 33.3% | 50.0% | |
| 57.14% | 7 | 6.0 | 872 | 14,538 | 0.0% | 66.7% | |
| 66.67% | 6 | 6.3 | 1,097 | 14,757 | 100.0% | 33.3% | |
| 66.67% | 6 | 4.5 | 1,024 | 15,585 | 0.0% | 66.7% | |
| 33.33% | 6 | 5.2 | 945 | 12,943 | 25.0% | 50.0% | |
| 66.67% | 6 | 6.7 | 1,044 | 12,454 | 50.0% | 100.0% | |
| 100.00% | 6 | 4.0 | 997 | 14,143 | 100.0% | 100.0% | |
| 33.33% | 6 | 7.0 | 1,073 | 13,483 | 50.0% | 0.0% | |
| 66.67% | 6 | 5.9 | 754 | 12,586 | 33.3% | 100.0% | |
| 20.00% | 5 | 3.2 | 1,009 | 13,047 | 0.0% | 33.3% | |
| 60.00% | 5 | 0.9 | 620 | 13,585 | 0.0% | 75.0% | |
| 80.00% | 5 | 6.3 | 862 | 14,050 | 66.7% | 100.0% | |
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Zed vs Vayne - Frequently Asked Questions
How does Zed do against Vayne in League of Legends?
Vayne wins the Zed vs Vayne matchup with a 52.9% win rate compared to Zed's 47.1%, a 5.9 percentage point difference. This data is based on 17 recent ranked games in patch 26.10.
How does Zed do against Vayne in the early game?
In the early game, Zed has the advantage against Vayne with a 50.0% win rate versus 50.0%. Zed players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Zed do against Vayne in the late game?
In the late game, Vayne takes over the Zed vs Vayne matchup with a 60.0% win rate compared to 40.0%. Vayne scales better into team fights and objective contests after 25 minutes.
Who wins the Zed vs Vayne matchup?
Vayne wins the matchup against Zed with a 52.9% win rate in League of Legends patch 26.10. The 5.9 percentage point advantage means Vayne is significantly favored in this lane matchup based on 17 games analyzed.
What is the best Zed build against Vayne?
The best Zed build against Vayne includes Voltaic Cyclosword, Axiom Arc, Serpent's Fang with Crimson Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Zed runes against Vayne?
The best Zed runes against Vayne use the Inspiration primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Zed vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Zed counter Vayne?
No, Zed struggles against Vayne with only a 47.1% win rate. Vayne has the advantage in this matchup. Zed players should focus on safe farming and avoiding extended trades to minimize Vayne's lead.
How do I play Zed against Vayne?
When playing Zed against Vayne, play cautiously and avoid Vayne's power spikes. Look for jungle assistance and team-dependent plays since Vayne has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.