Zed - League of Legends Champion
Win Rate
48.8%
Pick Rate
3.2%

Zedvs Vayne

FAssassin
Patch26.7
Matches508,082
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 14, 2026
MethodologyData Methodology

Zed vs Vayne is a decisive matchup in LoL patch 26.7. Zed wins with a 66.7% win rate (+33.3%) over Vayne based on 6 games. Zed holds the advantage in both the early and late game. Below you'll find the best Zed build, runes, laning stats, and strategies for the Zed vs Vayne matchup.

Zed Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Zed performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 66.7% win rateVayne(66.7%)
Zed - 66.7% win rate in this matchup
Zed
66.7% WR
VS
Vayne vs Zed matchup - 33.3% win rate
Vayne
33.3% WR

Who Wins the Zed vs Vayne Matchup?

Zed wins the Zed vs Vayne matchup
Winner
Zed
Matches: 6
66.7%
Win Rate
33.3%
5.5
CS / min
4.6
863
DMG / min
570
11,571
Gold / game
9,105
167
Heal / min
256
470
DMG Mitigated / min
548
0.2
CC / min
0.3
75.0%
Early Game WR
25.0%
50.0%
Late Game WR
50.0%

Zed vs Vayne Matchup Summary

The Zed vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Zed wins with a 66.7% win rate compared to Vayne's 33.3%, giving Zed a 33.3 percentage point advantage. Zed dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Vayne leads by 0.1s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Zed players can confidently pick into Vayne and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vayne away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Zed vs Vayne Laning Phase Breakdown

Zed wins the laning phase against Vayne in League of Legends

Zed is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Zed holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
5.5Zed
4.6Vayne
Zed significantly out-farms Vayne by 0.9 CS per minute, accumulating an estimated 14 CS lead by mid game. This substantial farming gap gives Zed a major gold advantage and earlier item completions. Vayne players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
863Zed
570Vayne
Zed heavily out-damages Vayne by 293 DMG/min, dominating both short trades and all-in fights. Vayne should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Zed's sustained damage advantage take over.
Economy
11,571Zed
9,105Vayne
Zed generates a commanding 2,466 more gold per game than Vayne. This substantial economic advantage means Zed consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Vayne should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.2Zed
0.3Vayne
Both Zed and Vayne provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
637Zed
804Vayne
Vayne vastly out-sustains Zed, healing and mitigating 167 more damage per minute. This massive durability gap means Vayne can absorb significant punishment and remain in lane while Zed is forced to recall. Building grievous wounds early is essential for Zed, and focusing on burst trade patterns rather than sustained fights is critical.

Best Zed Build Against Vayne

Ionian Boots of Lucidity is the optimal boots choice against Vayne, providing the mobility and stats Zed needs most in this matchup. The top-performing core items for Zed against Vayne are Voltaic Cyclosword, Eclipse and Edge of Night. This combination gives Zed an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Zed vs Vayne matchup.

Early Game vs Late Game

Early Game
Zed
75.0%
+50.0% advantage
Zed early game win rateZed75.0%
Vayne early game win rateVayne25.0%
Late Game
Zed
50.0%
+0.0% advantage
Zed late game win rateZed50.0%
Vayne late game win rateVayne50.0%

Zed dominates the early game (first 15 minutes) with a commanding 75.0% win rate — a 50.0 percentage point lead over Vayne. This lopsided early game means Zed can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Zed at 50.0% win rate — only 0.0 points ahead of Vayne. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

Zed holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Zed Runes Against Vayne

Domination rune tree - Zed primary runes vs VayneDomination
Dark Harvest - best Zed rune vs VayneSudden Impact - best Zed rune vs VayneSixth Sense - best Zed rune vs VayneUltimate Hunter - best Zed rune vs Vayne
Sorcery rune tree - Zed secondary runes vs VayneSorcery
Gathering Storm - best Zed rune vs VayneAxiom Arcanist - best Zed rune vs Vayne
100.0% WR

Running Domination primary with Sorcery secondary allows Zed to press their advantage against Vayne, amplifying the strengths that make this a favorable matchup.


Zed matchup data for League of Legends patch 26.7. The table below shows Zed's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zed build, runes, laning stats, and early vs late game analysis for that specific matchup.

Zed matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
52.53%1586.493812,91352.0%53.0%
55.65%1246.791113,15651.7%59.1%
44.92%1186.686512,85848.0%42.6%
53.49%866.21,02013,51154.5%52.8%
47.67%865.492311,89048.0%47.2%
51.81%836.582512,42645.0%58.1%
51.81%836.596012,61150.0%53.9%
39.76%836.394912,89246.1%34.1%
38.75%806.189713,43331.0%43.1%
51.32%766.394812,90453.3%50.0%
54.05%746.696913,64462.5%47.6%
52.11%716.392813,49253.6%51.2%
53.73%676.495313,18348.3%57.9%
53.73%676.392913,58752.0%54.8%
38.81%676.484412,49935.7%41.0%
45.45%666.097412,89142.9%47.4%
42.86%635.484712,44444.0%42.1%
47.46%596.278711,65641.9%53.6%
51.02%496.181112,45941.7%60.0%
55.32%476.41,05912,92752.0%59.1%
53.19%475.290513,35447.6%57.7%
51.16%436.179812,46655.6%48.0%
55.81%436.31,00512,88370.0%43.5%
45.24%426.093212,73055.0%36.4%
50.00%386.087812,99443.8%54.5%
55.26%386.41,01312,14450.0%62.5%
57.89%385.394213,18557.1%58.8%
62.16%376.81,02712,63365.0%58.8%
45.71%356.389713,36642.9%47.6%
51.43%356.082612,55235.3%66.7%
64.71%345.294013,85662.5%65.4%
55.88%346.71,03112,66862.5%50.0%
64.52%316.71,02012,82850.0%73.7%
51.61%316.193912,12041.2%64.3%
28.57%286.174212,01333.3%23.1%
51.85%276.71,12614,66644.4%55.6%
60.00%256.383012,22862.5%58.8%
52.00%251.475713,07853.3%50.0%
45.83%241.986015,14066.7%33.3%
25.00%245.51,09611,93023.1%27.3%
56.52%232.694414,33558.3%54.5%
26.09%236.588712,96025.0%26.7%
40.91%226.583911,97837.5%42.9%
36.36%221.577914,14237.5%35.7%
57.14%216.496514,26280.0%50.0%
38.10%213.584112,76236.4%40.0%
45.00%206.21,07114,07944.4%45.5%
55.00%202.184414,31475.0%41.7%
50.00%205.181511,35740.0%60.0%
36.84%191.978813,42554.5%12.5%
52.63%197.11,16414,33575.0%36.4%
61.11%186.31,05214,60383.3%50.0%
41.18%172.099118,0220.0%50.0%
56.25%162.21,12712,97054.5%60.0%
62.50%166.81,08814,22766.7%60.0%
60.00%153.398514,34457.1%62.5%
53.33%156.289313,02971.4%37.5%
60.00%155.588711,64050.0%71.4%
40.00%155.086613,68442.9%37.5%
57.14%146.490311,75457.1%57.1%
64.29%142.581914,26675.0%60.0%
30.77%136.576811,77142.9%16.7%
76.92%135.81,00713,169100.0%62.5%
58.33%121.293115,24466.7%55.6%
45.45%111.592313,35525.0%57.1%
36.36%116.21,01114,35940.0%33.3%
27.27%116.31,06213,15760.0%0.0%
72.73%117.196015,222100.0%57.1%
0.00%112.583515,2560.0%0.0%
54.55%112.276313,943100.0%28.6%
45.45%116.31,04312,17950.0%42.9%
36.36%111.685715,62033.3%37.5%
40.00%106.080210,86550.0%25.0%
50.00%103.073213,45950.0%50.0%
60.00%101.477613,17550.0%66.7%
40.00%102.981012,81550.0%33.3%
33.33%91.199915,66325.0%40.0%
88.89%94.379214,51175.0%100.0%
33.33%95.579214,5410.0%37.5%
44.44%97.494510,26750.0%33.3%
44.44%96.797411,52060.0%25.0%
55.56%94.298615,9180.0%71.4%
55.56%91.196014,344100.0%20.0%
50.00%81.31,23616,25433.3%60.0%
50.00%87.187713,24175.0%25.0%
75.00%82.11,12116,031100.0%60.0%
37.50%81.481516,4860.0%37.5%
50.00%86.51,11814,86866.7%40.0%
42.86%75.965811,13320.0%100.0%
42.86%73.51,04014,12540.0%50.0%
71.43%75.295713,3730.0%83.3%
57.14%75.01,13615,60150.0%66.7%
85.71%71.580114,24175.0%100.0%
57.14%70.981914,31350.0%60.0%
16.67%63.997917,0120.0%16.7%
83.33%65.974711,255100.0%66.7%
66.67%61.880912,48080.0%0.0%
66.67%65.586311,57175.0%50.0%
50.00%67.21,09112,97433.3%66.7%
33.33%64.967011,33033.3%33.3%
66.67%61.379119,114100.0%60.0%
80.00%56.41,71219,228100.0%75.0%
40.00%52.170515,1850.0%50.0%
60.00%56.195213,48550.0%66.7%
20.00%51.061611,1410.0%33.3%
60.00%54.585912,09433.3%100.0%
80.00%52.698813,047100.0%66.7%
20.00%51.095913,8650.0%33.3%
60.00%56.078713,8250.0%100.0%
40.00%55.993013,3000.0%50.0%
40.00%56.59519,98333.3%50.0%
80.00%57.41,25316,097100.0%66.7%
40.00%57.31,34517,6690.0%40.0%

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Zed vs Vayne - Frequently Asked Questions

How does Zed do against Vayne in League of Legends?

Zed wins the Zed vs Vayne matchup with a 66.7% win rate compared to Vayne's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.7.

How does Zed do against Vayne in the early game?

In the early game, Zed has the advantage against Vayne with a 75.0% win rate versus 25.0%. Zed players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Zed do against Vayne in the late game?

In the late game, Zed takes over the Zed vs Vayne matchup with a 50.0% win rate compared to 50.0%. Zed scales better into team fights and objective contests after 25 minutes.

Who wins the Zed vs Vayne matchup?

Zed wins the matchup against Vayne with a 66.7% win rate in League of Legends patch 26.7. The 33.3 percentage point advantage means Zed is significantly favored in this lane matchup based on 6 games analyzed.

What is the best Zed build against Vayne?

The best Zed build against Vayne includes Voltaic Cyclosword, Eclipse, Edge of Night with Ionian Boots of Lucidity. Check the matchup breakdown above for the full item path and build order.

What are the best Zed runes against Vayne?

The best Zed runes against Vayne use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Zed vs Vayne matchup. See the full rune breakdown in the matchup comparison above.

Does Zed counter Vayne?

Yes, Zed has a favorable matchup against Vayne with a 66.7% win rate. Zed strongly counters Vayne in lane based on current patch 26.7 data.

How do I play Zed against Vayne?

When playing Zed against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.