Vayne - League of Legends Champion
Win Rate
50.6%
Pick Rate
4.6%

Vaynevs Zed

AMarksmanAssassin
Patch26.4
Matches974,630
LaneAll Lanes
TierAll Tiers
Last UpdatedFeb 27, 2026
MethodologyData Methodology

Vayne vs Zed is a very close matchup in LoL patch 26.4. Vayne wins with a 50.0% win rate (+0.0%) over Zed based on 12 games. Zed wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Zed matchup.

Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Zed - 50.0% win rateZed(50.0%)
Vayne - 50.0% win rate in this matchup
Vayne
50.0% WR
VS
Zed vs Vayne matchup - 50.0% win rate
Zed
50.0% WR

Who Wins the Vayne vs Zed Matchup?

Vayne wins the Vayne vs Zed matchup
Winner
Vayne
Matches: 12
50.0%
Win Rate
50.0%
5.7
CS / min
5.5
897
DMG / min
1,085
15,265
Gold / game
16,243
324
Heal / min
134
675
DMG Mitigated / min
648
0.4
CC / min
0.3
33.3%
Early Game WR
66.7%
55.6%
Late Game WR
44.4%

Vayne vs Zed Matchup Summary

The Vayne vs Zed matchup is essentially a coin-flip matchup in League of Legends ranked play. Based on 12 recent matches analyzed, Vayne wins with a 50.0% win rate compared to Zed's 50.0%, giving Vayne a 0.0 percentage point advantage. Game phase dynamics play a critical role here: Zed controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Zed needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Vayne leads by 0.1s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a statistical edge, but the margin is close enough that respecting Zed's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Zed Laning Phase Breakdown

Vayne wins the laning phase against Zed in League of Legends

Vayne is favored during the laning phase against Zed, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.

Farming
5.7Vayne
5.5Zed
Vayne and Zed farm at nearly identical rates in this matchup, with only a 0.3 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
897Vayne
1,085Zed
Zed heavily out-damages Vayne by 188 DMG/min, dominating both short trades and all-in fights. Vayne should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Zed's sustained damage advantage take over.
Economy
15,265Vayne
16,243Zed
Zed generates a commanding 978 more gold per game than Vayne. This substantial economic advantage means Zed consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Vayne should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.4Vayne
0.3Zed
Both Vayne and Zed provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
999Vayne
781Zed
Vayne vastly out-sustains Zed, healing and mitigating 218 more damage per minute. This massive durability gap means Vayne can absorb significant punishment and remain in lane while Zed is forced to recall. Building grievous wounds early is essential for Zed, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Zed

Gunmetal Greaves is the optimal boots choice against Zed, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Zed are Terminus, Blade of The Ruined King and Guinsoo's Rageblade. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Zed matchup.

Early Game vs Late Game

Early Game
Zed
66.7%
+33.3% advantage
Vayne early game win rateVayne33.3%
Zed early game win rateZed66.7%
Late Game
Vayne
55.6%
+11.1% advantage
Vayne late game win rateVayne55.6%
Zed late game win rateZed44.4%

Zed dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Vayne. This lopsided early game means Zed can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Vayne is far superior in the late game (25+ minutes), boasting a 55.6% win rate — 11.1 points above Zed. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Zed must aggressively press their early advantage and close out the game before Vayne reaches their scaling breakpoints. If Vayne survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Vayne Runes Against Zed

Precision rune tree - Vayne primary runes vs ZedPrecision
Press the Attack - best Vayne rune vs ZedTriumph - best Vayne rune vs ZedLegend: Alacrity - best Vayne rune vs ZedCoup de Grace - best Vayne rune vs Zed
Inspiration rune tree - Vayne secondary runes vs ZedInspiration
Cash Back - best Vayne rune vs ZedJack Of All Trades - best Vayne rune vs Zed
100.0% WR

The Precision primary with Inspiration secondary combination helps Vayne maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Zed.


Vayne matchup data for League of Legends patch 26.4. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.4
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
51.15%6596.180113,24352.4%50.1%
50.60%5865.981413,66251.6%49.9%
50.09%5666.386713,36649.8%50.3%
53.30%4756.186213,38751.8%54.4%
49.40%4256.590914,01844.3%53.8%
45.15%3626.180413,21839.0%50.3%
56.70%3596.491914,03553.3%59.7%
52.94%3126.491114,09052.2%53.4%
46.40%2516.085013,49655.3%40.1%
53.42%2346.585913,17254.5%52.5%
55.14%2166.288513,16656.0%54.3%
54.55%1876.593214,48459.1%51.7%
51.61%1876.284613,36957.7%44.9%
54.14%1816.281013,07049.4%58.5%
48.82%1706.390513,44549.4%48.2%
53.70%1635.985713,74856.3%52.0%
48.70%1556.187113,65544.6%51.7%
50.42%1195.986614,05246.8%52.8%
56.19%1056.192513,93859.1%54.1%
48.98%986.184413,96447.1%50.0%
54.08%986.185411,82255.6%52.8%
61.29%946.593013,07159.5%62.8%
60.00%916.198512,31963.4%57.1%
55.81%875.81,03214,14447.1%61.5%
54.88%826.090513,50358.3%52.2%
46.91%816.385713,75443.2%50.0%
49.37%806.188313,63860.0%40.9%
51.90%796.489914,02648.5%54.4%
50.72%716.491712,08850.0%51.2%
42.03%706.288514,16529.2%48.9%
44.93%705.761511,53628.6%56.1%
43.48%696.31,39212,40937.0%47.6%
43.28%675.987911,17626.5%60.6%
56.67%615.565911,92131.6%68.3%
51.72%585.999911,10250.0%53.9%
47.37%576.71,01014,57452.0%43.8%
44.64%566.187513,78542.9%45.7%
57.14%566.11,00711,81653.9%60.0%
50.00%546.492713,26957.7%42.9%
49.06%536.31,04613,34750.0%48.5%
48.08%526.497511,85140.0%55.6%
50.98%516.489411,70642.1%56.3%
57.45%476.384712,01854.2%60.9%
47.73%446.492012,19055.0%41.7%
48.84%436.282412,11333.3%63.6%
48.78%426.497912,55350.0%47.8%
50.00%426.01,00011,70545.8%55.6%
70.73%416.892215,19371.4%70.4%
50.00%406.590010,91648.0%53.3%
51.28%397.398313,32652.6%50.0%
52.63%386.688413,01147.4%57.9%
32.43%375.971910,33620.8%53.9%
57.14%355.891514,68643.8%68.4%
45.71%355.682811,98344.4%47.1%
55.88%346.198612,04160.0%52.6%
60.61%335.980712,81150.0%68.4%
33.33%336.588813,38920.0%39.1%
46.88%326.094412,56630.0%54.5%
50.00%316.187311,55150.0%50.0%
50.00%305.972313,12238.5%58.8%
62.07%296.587112,59472.7%55.6%
48.15%286.191712,78150.0%46.7%
53.85%266.079812,54254.5%53.3%
50.00%266.280312,23140.0%56.3%
44.00%255.594411,60154.5%35.7%
50.00%246.580412,75063.6%38.5%
60.87%236.390914,13163.6%58.3%
43.48%236.589511,12741.7%45.5%
43.48%236.61,12712,56542.9%44.4%
43.48%235.287413,74262.5%33.3%
59.09%226.91,10214,21757.1%60.0%
54.55%226.185912,77960.0%50.0%
50.00%226.81,09813,97162.5%42.9%
36.84%206.486613,93240.0%33.3%
57.89%205.688114,08362.5%54.5%
52.63%195.97209,97854.5%50.0%
63.16%196.31,06115,663100.0%53.3%
50.00%185.881512,69742.9%54.5%
56.25%166.01,03012,56144.4%71.4%
50.00%166.592611,54340.0%66.7%
46.67%155.762510,93128.6%62.5%
66.67%156.780511,17863.6%75.0%
21.43%146.66639,40522.2%20.0%
38.46%136.393211,81633.3%42.9%
33.33%126.560010,67833.3%33.3%
50.00%125.789715,26533.3%55.6%
41.67%126.797615,74340.0%42.9%
58.33%125.978111,83020.0%85.7%
50.00%126.21,00412,25420.0%71.4%
41.67%126.881011,67620.0%57.1%
36.36%113.693813,26760.0%16.7%
50.00%102.41,04515,15333.3%57.1%
30.00%104.485313,51520.0%40.0%
40.00%104.877312,40933.3%50.0%
50.00%104.583010,90150.0%50.0%
40.00%106.094814,70440.0%40.0%
50.00%105.379011,45350.0%50.0%
30.00%106.676812,6370.0%37.5%
40.00%106.486611,63750.0%33.3%
44.44%94.082511,62340.0%50.0%
44.44%96.01,11312,12760.0%25.0%
25.00%84.275811,7450.0%66.7%
62.50%86.066012,870100.0%50.0%
14.29%83.25548,24016.7%0.0%
50.00%84.269712,89650.0%50.0%
42.86%74.167011,9290.0%60.0%
57.14%75.486112,5180.0%100.0%
71.43%76.684915,13250.0%80.0%
14.29%76.01,05415,4820.0%16.7%
50.00%65.195712,1060.0%60.0%
25.00%52.456711,13350.0%0.0%
60.00%56.877813,45350.0%66.7%
60.00%54.582216,075100.0%50.0%
40.00%51.385410,6460.0%100.0%
40.00%52.770614,2870.0%50.0%
40.00%53.11,07012,85150.0%0.0%
60.00%54.065111,403100.0%33.3%
60.00%56.41,09915,068100.0%33.3%
60.00%56.91,19213,2620.0%100.0%
🔍

Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.

Report an Issue

Vayne vs Zed - Frequently Asked Questions

How does Vayne do against Zed in League of Legends?

Vayne wins the Vayne vs Zed matchup with a 50.0% win rate compared to Zed's 50.0%, a 0.0 percentage point difference. This data is based on 12 recent ranked games in patch 26.4.

How does Vayne do against Zed in the early game?

In the early game, Zed has the advantage against Vayne with a 66.7% win rate versus 33.3%. Zed players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Zed in the late game?

In the late game, Vayne takes over the Vayne vs Zed matchup with a 55.6% win rate compared to 44.4%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Zed matchup?

Vayne wins the matchup against Zed with a 50.0% win rate in League of Legends patch 26.4. The 0.0 percentage point advantage means Vayne is slightly favored in this lane matchup based on 12 games analyzed.

What is the best Vayne build against Zed?

The best Vayne build against Zed includes Terminus, Blade of The Ruined King, Guinsoo's Rageblade with Gunmetal Greaves. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Zed?

The best Vayne runes against Zed use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Zed matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Zed?

Yes, Vayne has a favorable matchup against Zed with a 50.0% win rate. Vayne slightly edges out Zed in lane based on current patch 26.4 data.

How do I play Vayne against Zed?

When playing Vayne against Zed, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Zed. Build the recommended items and runes for this specific matchup for the best results.