Vayne - League of Legends Champion
Win Rate
50.4%
Pick Rate
5.3%

Vaynevs Zed

BMarksmanAssassin
Patch26.7
Matches508,082
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 14, 2026
MethodologyData Methodology

Vayne vs Zed is a decisive matchup in LoL patch 26.7. Zed wins with a 66.7% win rate (+33.3%) over Vayne based on 6 games. Zed wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Zed matchup.

Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Zed - 33.3% win rateZed(33.3%)
Vayne - 33.3% win rate in this matchup
Vayne
33.3% WR
VS
Zed vs Vayne matchup - 66.7% win rate
Zed
66.7% WR

Who Wins the Vayne vs Zed Matchup?

Zed wins the Vayne vs Zed matchup
Winner
Zed
Matches: 6
33.3%
Win Rate
66.7%
4.6
CS / min
5.5
570
DMG / min
863
9,105
Gold / game
11,571
256
Heal / min
167
548
DMG Mitigated / min
470
0.3
CC / min
0.2
25.0%
Early Game WR
75.0%
50.0%
Late Game WR
50.0%

Vayne vs Zed Matchup Summary

The Vayne vs Zed matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Zed wins with a 66.7% win rate compared to Vayne's 33.3%, giving Zed a 33.3 percentage point advantage. Game phase dynamics play a critical role here: Zed controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Zed needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Vayne leads by 0.1s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Zed has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Zed overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Zed Laning Phase Breakdown

Zed wins the laning phase against Vayne in League of Legends

Zed is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Zed holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
4.6Vayne
5.5Zed
Zed significantly out-farms Vayne by 0.9 CS per minute, accumulating an estimated 14 CS lead by mid game. This substantial farming gap gives Zed a major gold advantage and earlier item completions. Vayne players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
570Vayne
863Zed
Zed heavily out-damages Vayne by 293 DMG/min, dominating both short trades and all-in fights. Vayne should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Zed's sustained damage advantage take over.
Economy
9,105Vayne
11,571Zed
Zed generates a commanding 2,466 more gold per game than Vayne. This substantial economic advantage means Zed consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Vayne should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.3Vayne
0.2Zed
Both Vayne and Zed provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
804Vayne
637Zed
Vayne vastly out-sustains Zed, healing and mitigating 167 more damage per minute. This massive durability gap means Vayne can absorb significant punishment and remain in lane while Zed is forced to recall. Building grievous wounds early is essential for Zed, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Zed

Berserker's Greaves is the optimal boots choice against Zed, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Zed are Terminus, Blade of The Ruined King and Guinsoo's Rageblade. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Zed. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Zed matchup.

Early Game vs Late Game

Early Game
Zed
75.0%
+50.0% advantage
Vayne early game win rateVayne25.0%
Zed early game win rateZed75.0%
Late Game
Vayne
50.0%
+0.0% advantage
Vayne late game win rateVayne50.0%
Zed late game win rateZed50.0%

Zed dominates the early game (first 15 minutes) with a commanding 75.0% win rate — a 50.0 percentage point lead over Vayne. This lopsided early game means Zed can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Vayne at 50.0% win rate — only 0.0 points ahead of Zed. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

The power dynamics shift as the game progresses — Zed has the edge early, but Vayne gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Vayne Runes Against Zed

Precision rune tree - Vayne primary runes vs ZedPrecision
Lethal Tempo - best Vayne rune vs ZedTriumph - best Vayne rune vs ZedLegend: Alacrity - best Vayne rune vs ZedCoup de Grace - best Vayne rune vs Zed
Inspiration rune tree - Vayne secondary runes vs ZedInspiration
Magical Footwear - best Vayne rune vs ZedCosmic Insight - best Vayne rune vs Zed
100.0% WR

The Precision and Inspiration rune setup gives Vayne the best tools to compete against Zed in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Vayne matchup data for League of Legends patch 26.7. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.02%3576.081713,23145.3%52.0%
52.47%3246.289813,59649.3%55.2%
48.09%3146.283212,81944.0%52.7%
49.01%3025.982512,93747.5%50.3%
52.94%2726.083913,07152.8%53.1%
45.37%2276.496014,25446.9%44.2%
50.00%2226.493713,71750.0%50.0%
52.71%2036.585613,74148.9%56.0%
52.32%1516.582813,28755.4%49.4%
58.39%1496.695312,70051.6%63.5%
51.30%1155.881313,71761.5%42.9%
47.71%1096.088213,23938.2%57.4%
55.67%976.488012,62559.6%51.1%
51.55%976.380612,73552.5%50.0%
50.00%945.983213,59546.7%53.1%
36.36%886.279012,98330.0%41.7%
47.44%786.692813,28446.3%48.6%
61.33%756.692412,10266.7%55.6%
55.56%726.185813,24745.2%63.4%
57.35%686.085313,57456.0%58.1%
36.76%686.288112,39436.7%36.8%
52.54%596.383712,51848.5%57.7%
42.37%596.287012,82834.4%51.9%
38.60%575.760511,22540.0%37.0%
37.50%565.560110,77030.4%42.4%
43.40%536.21,04512,46744.4%42.3%
44.00%506.188613,06147.8%40.7%
53.06%496.11,21413,80450.0%55.2%
65.91%446.186913,29266.7%65.4%
56.82%445.692114,04761.1%53.9%
43.18%445.799611,54831.3%50.0%
50.00%406.384813,58435.3%60.9%
55.00%405.989314,58823.1%70.4%
57.50%406.395114,24860.0%56.7%
48.72%396.595213,49157.9%40.0%
57.89%386.01,02912,41355.0%61.1%
42.11%386.192313,74144.4%40.0%
54.05%377.092811,69252.4%56.3%
40.54%375.880412,22541.2%40.0%
40.00%355.71,14111,80838.9%41.2%
55.88%346.585611,12557.9%53.3%
50.00%326.098613,59966.7%43.5%
66.67%306.289612,54050.0%81.3%
56.67%306.298113,89653.9%58.8%
48.28%296.785812,18028.6%66.7%
55.17%296.31,02413,69462.5%46.1%
51.85%275.798412,39145.5%56.3%
61.54%266.185111,71961.5%61.5%
64.00%256.080811,77055.6%68.8%
44.00%256.892712,26342.9%45.5%
33.33%246.483511,60541.7%25.0%
56.52%235.592112,42462.5%53.3%
43.48%236.383712,92160.0%30.8%
40.91%226.678811,10141.7%40.0%
52.38%215.992313,47740.0%63.6%
60.00%205.290914,35220.0%73.3%
47.37%196.91,00811,89263.6%25.0%
50.00%186.273213,04560.0%37.5%
50.00%186.21,05312,78455.6%44.4%
44.44%186.483711,79542.9%45.5%
50.00%185.875412,37328.6%63.6%
76.47%176.91,02114,29680.0%75.0%
29.41%176.982911,89737.5%22.2%
41.18%176.086215,19160.0%33.3%
43.75%166.083811,77362.5%25.0%
56.25%166.690711,52757.1%55.6%
37.50%165.465913,20816.7%50.0%
68.75%166.793713,92583.3%60.0%
53.33%155.968611,41937.5%71.4%
73.33%156.485112,62177.8%66.7%
50.00%145.785111,11416.7%75.0%
42.86%144.364512,05114.3%71.4%
53.85%133.388514,16275.0%44.4%
53.85%135.71,05513,76250.0%55.6%
58.33%125.656210,02757.1%60.0%
25.00%124.586213,08325.0%25.0%
50.00%126.378413,32833.3%66.7%
27.27%116.277113,46233.3%25.0%
63.64%116.387415,82666.7%62.5%
36.36%116.665110,70650.0%20.0%
45.45%115.591912,62950.0%40.0%
72.73%116.474510,85071.4%75.0%
45.45%116.01,06414,50840.0%50.0%
70.00%106.699613,49075.0%66.7%
40.00%106.887613,21633.3%50.0%
55.56%96.393712,28633.3%100.0%
44.44%96.21,07715,702100.0%28.6%
33.33%96.877411,06920.0%50.0%
25.00%85.569310,37825.0%25.0%
50.00%85.99738,78533.3%100.0%
37.50%81.983414,72733.3%40.0%
42.86%75.690112,809100.0%20.0%
0.00%76.655810,7000.0%0.0%
42.86%74.665114,53850.0%40.0%
71.43%76.168213,12675.0%66.7%
57.14%75.588812,31625.0%100.0%
57.14%75.489512,10050.0%66.7%
42.86%74.077311,64333.3%50.0%
57.14%72.51,31315,57625.0%100.0%
33.33%64.65709,10525.0%50.0%
66.67%65.91,08915,49350.0%75.0%
50.00%65.776213,18250.0%50.0%
50.00%61.989114,832100.0%40.0%
16.67%65.384410,4420.0%33.3%
0.00%65.979510,7240.0%0.0%
83.33%66.196311,361100.0%50.0%
50.00%66.380413,574100.0%40.0%
40.00%54.793914,778100.0%0.0%
60.00%51.71,19517,6480.0%75.0%
20.00%51.56919,37833.3%0.0%
60.00%55.31,10015,380100.0%50.0%
20.00%56.891512,5530.0%33.3%
40.00%56.51,02117,6030.0%40.0%

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Vayne vs Zed - Frequently Asked Questions

How does Vayne do against Zed in League of Legends?

Zed wins the Vayne vs Zed matchup with a 66.7% win rate compared to Vayne's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.7.

How does Vayne do against Zed in the early game?

In the early game, Zed has the advantage against Vayne with a 75.0% win rate versus 25.0%. Zed players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Zed in the late game?

In the late game, Vayne takes over the Vayne vs Zed matchup with a 50.0% win rate compared to 50.0%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Zed matchup?

Zed wins the matchup against Vayne with a 66.7% win rate in League of Legends patch 26.7. The 33.3 percentage point advantage means Zed is significantly favored in this lane matchup based on 6 games analyzed.

What is the best Vayne build against Zed?

The best Vayne build against Zed includes Terminus, Blade of The Ruined King, Guinsoo's Rageblade with Berserker's Greaves. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Zed?

The best Vayne runes against Zed use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Zed matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Zed?

No, Vayne struggles against Zed with only a 33.3% win rate. Zed has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Zed's lead.

How do I play Vayne against Zed?

When playing Vayne against Zed, play cautiously and avoid Zed's power spikes. Focus on safe farming — you outscale Zed in the late game. Use the matchup-specific build and runes above to optimize your chances.