Zyra - League of Legends Champion
Win Rate
49.9%
Pick Rate
3.3%

Zyravs Kai'Sa

CMageSupport
Patch26.9
Matches514,344
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 10, 2026
MethodologyData Methodology

Zyra vs Kai'Sa is a decisive matchup in LoL patch 26.9. Zyra wins with a 55.6% win rate (+11.1%) over Kai'Sa based on 9 games. Zyra holds the advantage in both the early and late game. Below you'll find the best Zyra build, runes, laning stats, and strategies for the Zyra vs Kai'Sa matchup.

Zyra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Zyra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Kai'Sa - 55.6% win rateKai'Sa(55.6%)
Zyra - 55.6% win rate in this matchup
Zyra
55.6% WR
VS
Kai'Sa vs Zyra matchup - 44.4% win rate
Kai'Sa
44.4% WR

Who Wins the Zyra vs Kai'Sa Matchup?

Zyra wins the Zyra vs Kai'Sa matchup
Winner
Zyra
Matches: 9
55.6%
Win Rate
44.4%
6.3
CS / min
5.8
1,326
DMG / min
871
11,238
Gold / game
11,426
96
Heal / min
188
308
DMG Mitigated / min
517
1.3
CC / min
0.1
50.0%
Early Game WR
50.0%
66.7%
Late Game WR
33.3%

Zyra vs Kai'Sa Matchup Summary

The Zyra vs Kai'Sa matchup is a decisive matchup in League of Legends ranked play. Based on 9 recent matches analyzed, Zyra wins with a 55.6% win rate compared to Kai'Sa's 44.4%, giving Zyra a 11.1 percentage point advantage. Zyra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Kai'Sa players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Zyra leads by 1.2s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Zyra players can confidently pick into Kai'Sa and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Kai'Sa away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Zyra vs Kai'Sa Laning Phase Breakdown

Zyra wins the laning phase against Kai'Sa in League of Legends

Zyra is favored during the laning phase against Kai'Sa, winning 3 out of 5 key stat categories. Zyra holds advantages in farming, damage and crowd control, making them the stronger laner in this matchup.

Farming
6.3Zyra
5.8Kai'Sa
Zyra edges out Kai'Sa by 0.5 CS per minute — a moderate farming advantage that adds up to roughly 8 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Zyra.
Damage
1,326Zyra
871Kai'Sa
Zyra heavily out-damages Kai'Sa by 455 DMG/min, dominating both short trades and all-in fights. Kai'Sa should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Zyra's sustained damage advantage take over.
Economy
11,238Zyra
11,426Kai'Sa
Zyra and Kai'Sa generate nearly equal gold per game, with just a 188 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
1.3Zyra
0.1Kai'Sa
Zyra brings significantly more crowd control than Kai'Sa, with 1.2 more seconds of CC per minute. This large utility gap makes Zyra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Kai'Sa should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
404Zyra
706Kai'Sa
Kai'Sa vastly out-sustains Zyra, healing and mitigating 301 more damage per minute. This massive durability gap means Kai'Sa can absorb significant punishment and remain in lane while Zyra is forced to recall. Building grievous wounds early is essential for Zyra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Zyra Build Against Kai'Sa

Sorcerer's Shoes is the optimal boots choice against Kai'Sa, providing the mobility and stats Zyra needs most in this matchup. The top-performing core items for Zyra against Kai'Sa are Liandry's Torment, Shadowflame and Morellonomicon. This combination gives Zyra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Kai'Sa. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Zyra vs Kai'Sa matchup.

Early Game vs Late Game

Early Game
Zyra
50.0%
+0.0% advantage
Zyra early game win rateZyra50.0%
Kai'Sa early game win rateKai'Sa50.0%
Late Game
Zyra
66.7%
+33.3% advantage
Zyra late game win rateZyra66.7%
Kai'Sa late game win rateKai'Sa33.3%

The early game (first 15 minutes) is a toss-up between Zyra and Kai'Sa, with Zyra holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Zyra is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Kai'Sa. Extended games heavily favor Zyra, whose kit and scaling make them a dominant force in team fights and objective control.

Zyra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Kai'Sa players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Zyra Runes Against Kai'Sa

Sorcery rune tree - Zyra primary runes vs Kai'SaSorcery
Deathfire Touch - best Zyra rune vs Kai'SaManaflow Band - best Zyra rune vs Kai'SaTranscendence - best Zyra rune vs Kai'SaScorch - best Zyra rune vs Kai'Sa
Precision rune tree - Zyra secondary runes vs Kai'SaPrecision
Presence of Mind - best Zyra rune vs Kai'SaCut Down - best Zyra rune vs Kai'Sa
100.0% WR

Running Sorcery primary with Precision secondary allows Zyra to press their advantage against Kai'Sa, amplifying the strengths that make this a favorable matchup.


Zyra matchup data for League of Legends patch 26.9. The table below shows Zyra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zyra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Zyra matchup win rates and stats in League of Legends patch 26.9
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
41.86%1721.97419,61746.3%39.0%
48.73%1581.87689,57544.8%51.6%
51.32%1522.073610,35251.8%51.0%
55.26%1142.178810,41558.7%52.9%
45.79%1071.87979,93241.9%48.4%
49.48%971.87379,96855.6%45.9%
44.68%941.87699,44336.8%50.0%
60.00%901.76329,21659.5%60.4%
50.00%902.185610,99550.0%50.0%
39.53%861.982410,04937.0%40.7%
54.88%821.77999,50563.9%47.8%
48.57%701.87479,20348.1%48.8%
53.03%661.85859,20851.7%54.0%
53.97%631.97749,23265.5%44.1%
59.68%622.07749,75465.2%56.4%
48.39%622.178410,47545.0%50.0%
56.45%621.778610,40871.4%48.8%
60.00%551.98009,85063.3%56.0%
55.77%521.982010,86761.1%52.9%
62.50%482.37149,89966.7%59.3%
39.58%482.690210,34837.5%40.6%
56.25%481.886310,53261.5%54.3%
51.11%452.17519,85682.3%32.1%
55.56%452.884410,55357.9%53.9%
48.72%391.985311,22844.4%50.0%
48.57%352.885311,53560.0%40.0%
57.58%331.675010,12491.7%38.1%
63.64%331.77068,64856.3%70.6%
48.39%311.87289,21142.9%52.9%
43.33%301.88499,26840.0%45.0%
41.38%292.077810,33815.4%62.5%
44.83%291.088013,13755.6%40.0%
59.26%272.076611,08954.5%62.5%
48.15%275.58839,86058.3%40.0%
65.38%261.280011,51071.4%58.3%
68.00%252.174710,83571.4%66.7%
54.55%221.971010,70171.4%46.7%
40.00%204.787810,70333.3%50.0%
35.00%201.880911,94557.1%23.1%
65.00%201.691412,99885.7%53.9%
52.63%191.692413,57050.0%53.9%
44.44%181.489912,89657.1%36.4%
44.44%182.186510,13833.3%50.0%
35.29%172.37639,01133.3%40.0%
47.06%171.87139,91742.9%50.0%
47.06%171.587414,11150.0%46.1%
75.00%161.692013,22550.0%90.0%
43.75%162.07658,09850.0%37.5%
56.25%161.699413,19866.7%50.0%
60.00%153.782910,34650.0%66.7%
33.33%155.086311,9460.0%50.0%
35.71%142.281411,44316.7%50.0%
35.71%141.876810,71060.0%22.2%
61.54%133.988910,13380.0%50.0%
46.15%136.41,06914,15333.3%50.0%
61.54%131.888512,815100.0%50.0%
66.67%121.493712,21266.7%66.7%
41.67%121.567611,47828.6%60.0%
25.00%121.488212,2100.0%50.0%
41.67%121.789013,14033.3%44.4%
41.67%123.177810,76240.0%42.9%
54.55%114.080310,66140.0%66.7%
63.64%116.91,11713,94466.7%62.5%
63.64%111.482213,6010.0%77.8%
54.55%112.47899,31180.0%33.3%
70.00%101.782511,907100.0%62.5%
40.00%104.61,01212,3950.0%50.0%
77.78%96.81,14810,39985.7%50.0%
55.56%92.477311,57375.0%40.0%
44.44%93.582510,38075.0%20.0%
66.67%95.685412,341100.0%62.5%
55.56%93.086413,030100.0%42.9%
55.56%96.31,32611,23850.0%66.7%
50.00%82.51,1489,56475.0%25.0%
37.50%86.685810,14566.7%20.0%
37.50%84.79049,88740.0%33.3%
37.50%82.581411,1580.0%50.0%
37.50%81.286911,76350.0%25.0%
62.50%81.264811,03675.0%50.0%
62.50%81.582114,26133.3%80.0%
50.00%86.083010,42760.0%33.3%
85.71%76.197111,27575.0%100.0%
85.71%71.378110,846100.0%80.0%
42.86%73.671110,4320.0%50.0%
42.86%72.11,09515,0770.0%50.0%
42.86%73.296911,0830.0%50.0%
57.14%74.093711,4320.0%66.7%
42.86%75.69539,31375.0%0.0%
57.14%72.46719,65675.0%33.3%
71.43%71.686114,007100.0%60.0%
71.43%73.679111,488100.0%60.0%
57.14%76.290811,60850.0%60.0%
57.14%75.57147,91640.0%100.0%
28.57%71.275710,26440.0%0.0%
33.33%61.31,04615,14650.0%25.0%
33.33%62.081710,72150.0%0.0%
50.00%62.894213,7420.0%50.0%
66.67%62.789811,4030.0%80.0%
66.67%61.569112,62166.7%66.7%
66.67%61.267510,73275.0%50.0%
33.33%62.081112,0650.0%50.0%
16.67%66.46707,50320.0%0.0%
83.33%61.490513,37950.0%100.0%
80.00%51.61,21814,7410.0%80.0%
20.00%51.878811,34150.0%0.0%
60.00%51.177011,587100.0%33.3%
80.00%54.47898,096100.0%50.0%
80.00%51.358310,33275.0%100.0%
20.00%54.01,18512,6000.0%33.3%
60.00%52.078510,818100.0%33.3%
60.00%51.21,02113,6940.0%75.0%

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Zyra vs Kai'Sa - Frequently Asked Questions

How does Zyra do against Kai'Sa in League of Legends?

Zyra wins the Zyra vs Kai'Sa matchup with a 55.6% win rate compared to Kai'Sa's 44.4%, a 11.1 percentage point difference. This data is based on 9 recent ranked games in patch 26.9.

How does Zyra do against Kai'Sa in the early game?

In the early game, Zyra has the advantage against Kai'Sa with a 50.0% win rate versus 50.0%. Zyra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Zyra do against Kai'Sa in the late game?

In the late game, Zyra takes over the Zyra vs Kai'Sa matchup with a 66.7% win rate compared to 33.3%. Zyra scales better into team fights and objective contests after 25 minutes.

Who wins the Zyra vs Kai'Sa matchup?

Zyra wins the matchup against Kai'Sa with a 55.6% win rate in League of Legends patch 26.9. The 11.1 percentage point advantage means Zyra is significantly favored in this lane matchup based on 9 games analyzed.

What is the best Zyra build against Kai'Sa?

The best Zyra build against Kai'Sa includes Liandry's Torment, Shadowflame, Morellonomicon with Sorcerer's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Zyra runes against Kai'Sa?

The best Zyra runes against Kai'Sa use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Zyra vs Kai'Sa matchup. See the full rune breakdown in the matchup comparison above.

Does Zyra counter Kai'Sa?

Yes, Zyra has a favorable matchup against Kai'Sa with a 55.6% win rate. Zyra strongly counters Kai'Sa in lane based on current patch 26.9 data.

How do I play Zyra against Kai'Sa?

When playing Zyra against Kai'Sa, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.