Seraphine - League of Legends Champion
Win Rate
50.9%
Pick Rate
4.9%

Seraphinevs Zyra

ASupportMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 21, 2026
MethodologyData Methodology

Seraphine vs Zyra is a moderate matchup in LoL patch 26.7. Zyra wins with a 52.4% win rate (+4.9%) over Seraphine based on 103 games. Zyra wins the early laning phase while Seraphine scales better into the late game. Below you'll find the best Seraphine build, runes, laning stats, and strategies for the Seraphine vs Zyra matchup.

Seraphine Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Seraphine performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Zyra - 47.6% win rateZyra(47.6%)
Seraphine - 47.6% win rate in this matchup
Seraphine
47.6% WR
VS
Zyra vs Seraphine matchup - 52.4% win rate
Zyra
52.4% WR

Who Wins the Seraphine vs Zyra Matchup?

Zyra wins the Seraphine vs Zyra matchup
Winner
Zyra
Matches: 103
47.6%
Win Rate
52.4%
1.5
CS / min
1.9
444
DMG / min
747
9,601
Gold / game
10,163
327
Heal / min
102
373
DMG Mitigated / min
292
1.1
CC / min
1.7
36.6%
Early Game WR
63.4%
54.8%
Late Game WR
45.2%

Seraphine vs Zyra Matchup Summary

The Seraphine vs Zyra matchup is a moderate matchup in League of Legends ranked play. Based on 103 recent matches analyzed, Zyra wins with a 52.4% win rate compared to Seraphine's 47.6%, giving Zyra a 4.9 percentage point advantage. Game phase dynamics play a critical role here: Zyra controls the early laning stage, but Seraphine outscales as the game goes longer. The matchup shifts dramatically depending on game length — Zyra needs to press advantages before Seraphine reaches their power spikes, while Seraphine should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Seraphine leads by 306 HP/min — a difference that heavily influences the outcome of trades and skirmishes. While Zyra is slightly favored, Seraphine can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Zyra's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Seraphine vs Zyra Laning Phase Breakdown

Zyra wins the laning phase against Seraphine in League of Legends

Zyra is favored during the laning phase against Seraphine, winning 4 out of 5 key stat categories. Zyra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
1.5Seraphine
1.9Zyra
Zyra edges out Seraphine by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 6 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Zyra.
Damage
444Seraphine
747Zyra
Zyra heavily out-damages Seraphine by 303 DMG/min, dominating both short trades and all-in fights. Seraphine should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Zyra's sustained damage advantage take over.
Economy
9,601Seraphine
10,163Zyra
Zyra earns 562 more gold per game than Seraphine, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Zyra slightly faster item completions.
Utility
1.1Seraphine
1.7Zyra
Zyra provides 0.6 seconds more crowd control per minute than Seraphine, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Zyra coordinate with their jungler and control the pace of skirmishes.
Sustain
700Seraphine
394Zyra
Seraphine vastly out-sustains Zyra, healing and mitigating 306 more damage per minute. This massive durability gap means Seraphine can absorb significant punishment and remain in lane while Zyra is forced to recall. Building grievous wounds early is essential for Zyra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Seraphine Build Against Zyra

Ionian Boots of Lucidity is the optimal boots choice against Zyra, providing the mobility and stats Seraphine needs most in this matchup. The top-performing core items for Seraphine against Zyra are Echoes of Helia, Rylai's Crystal Scepter and Diadem of Songs. This combination gives Seraphine an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 3 games — well above average and making it the top item path against Zyra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Seraphine vs Zyra matchup.

Early Game vs Late Game

Early Game
Zyra
63.4%
+26.8% advantage
Seraphine early game win rateSeraphine36.6%
Zyra early game win rateZyra63.4%
Late Game
Seraphine
54.8%
+9.7% advantage
Seraphine late game win rateSeraphine54.8%
Zyra late game win rateZyra45.2%

Zyra dominates the early game (first 15 minutes) with a commanding 63.4% win rate — a 26.8 percentage point lead over Seraphine. This lopsided early game means Zyra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Seraphine is far superior in the late game (25+ minutes), boasting a 54.8% win rate — 9.7 points above Zyra. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Zyra must aggressively press their early advantage and close out the game before Seraphine reaches their scaling breakpoints. If Seraphine survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Seraphine Runes Against Zyra

Sorcery rune tree - Seraphine primary runes vs ZyraSorcery
Arcane Comet - best Seraphine rune vs ZyraManaflow Band - best Seraphine rune vs ZyraTranscendence - best Seraphine rune vs ZyraScorch - best Seraphine rune vs Zyra
Inspiration rune tree - Seraphine secondary runes vs ZyraInspiration
Biscuit Delivery - best Seraphine rune vs ZyraCosmic Insight - best Seraphine rune vs Zyra
53.3% WR

The Sorcery and Inspiration rune setup gives Seraphine the best tools to compete against Zyra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Seraphine matchup data for League of Legends patch 26.7. The table below shows Seraphine's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Seraphine build, runes, laning stats, and early vs late game analysis for that specific matchup.

Seraphine matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
54.18%2991.64439,72745.0%59.6%
44.49%2631.34388,73041.4%48.0%
53.94%2411.34619,24352.6%55.2%
53.01%1831.44589,30748.8%56.4%
53.59%1811.44469,09849.4%57.5%
53.66%1641.44779,15159.3%48.2%
51.57%1591.54879,18454.3%49.4%
56.96%1581.44609,12365.1%51.6%
51.45%1381.44108,92450.8%52.1%
57.58%1321.44559,01657.4%57.8%
44.44%1261.34078,50942.9%46.0%
48.72%1171.655210,13343.2%51.3%
55.17%1161.54939,75339.1%65.7%
48.28%1161.754110,06752.2%45.7%
54.29%1051.34268,52558.2%50.0%
47.57%1031.54449,60136.6%54.8%
53.92%1021.44648,93753.9%54.0%
50.50%1011.43578,58654.9%46.0%
65.31%982.04699,74265.0%65.5%
51.11%901.45449,00546.1%54.9%
60.67%891.45258,87651.2%69.6%
48.05%771.64329,06447.1%48.8%
48.48%661.64499,83052.0%46.3%
56.06%661.446210,05756.0%56.1%
59.09%661.34709,19553.3%63.9%
51.52%661.45339,38642.9%57.9%
50.00%561.34318,78350.0%50.0%
50.91%555.059410,15445.7%60.0%
61.11%541.45039,73561.1%61.1%
45.10%511.45549,19748.0%42.3%
56.00%501.64589,66571.4%44.8%
68.09%471.34338,79683.3%52.2%
41.30%461.44408,44340.7%42.1%
55.26%386.575312,73061.1%50.0%
41.67%361.55229,34566.7%23.8%
45.71%351.45389,51041.2%50.0%
51.43%356.577612,68062.5%42.1%
41.18%341.95239,70342.9%40.0%
62.50%324.466312,14861.5%63.2%
61.54%261.45069,89770.0%56.3%
57.69%265.866912,09666.7%50.0%
72.00%253.654911,21477.8%68.8%
47.83%231.34387,54662.5%14.3%
39.13%231.34279,80042.9%37.5%
45.45%225.768813,31257.1%40.0%
42.86%212.04569,77930.0%54.5%
60.00%206.873212,63062.5%58.3%
68.42%192.25288,37271.4%60.0%
52.63%194.566310,72362.5%45.5%
77.78%185.262111,90780.0%75.0%
50.00%182.23929,53214.3%72.7%
17.65%171.95419,5550.0%30.0%
68.75%166.175711,132100.0%44.4%
56.25%165.061711,17950.0%58.3%
37.50%161.44408,74328.6%44.4%
40.00%155.879112,89180.0%20.0%
53.33%152.65158,83558.3%33.3%
60.00%156.969012,35375.0%42.9%
57.14%141.65038,97662.5%50.0%
50.00%126.066912,17266.7%33.3%
58.33%121.95109,80057.1%60.0%
41.67%124.362911,9680.0%50.0%
50.00%125.572511,57837.5%75.0%
45.45%111.83348,40757.1%25.0%
45.45%111.448611,0260.0%50.0%
20.00%101.94449,6570.0%40.0%
30.00%106.083411,91850.0%16.7%
66.67%95.04869,88271.4%50.0%
66.67%96.791812,31350.0%100.0%
44.44%91.652310,69633.3%50.0%
66.67%95.06849,58460.0%75.0%
55.56%95.878611,74075.0%40.0%
62.50%86.375213,234100.0%50.0%
62.50%84.164710,851100.0%0.0%
62.50%86.072611,59850.0%75.0%
50.00%81.63948,88825.0%75.0%
50.00%82.659011,57450.0%50.0%
37.50%84.34689,60866.7%20.0%
50.00%86.075212,12750.0%50.0%
75.00%81.84619,71750.0%100.0%
50.00%84.75939,70720.0%100.0%
28.57%71.54699,3480.0%50.0%
57.14%72.24578,64566.7%50.0%
85.71%71.55068,91275.0%100.0%
42.86%71.44499,4630.0%60.0%
50.00%63.866510,38850.0%50.0%
50.00%61.253910,07150.0%50.0%
50.00%62.45769,27866.7%33.3%
50.00%65.060611,31766.7%33.3%
40.00%56.077711,01533.3%50.0%
20.00%55.151210,8920.0%25.0%
60.00%55.872310,033100.0%50.0%
20.00%51.43949,2580.0%33.3%
80.00%54.677910,15775.0%100.0%
40.00%52.76589,47233.3%50.0%

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Seraphine vs Zyra - Frequently Asked Questions

How does Seraphine do against Zyra in League of Legends?

Zyra wins the Seraphine vs Zyra matchup with a 52.4% win rate compared to Seraphine's 47.6%, a 4.9 percentage point difference. This data is based on 103 recent ranked games in patch 26.7.

How does Seraphine do against Zyra in the early game?

In the early game, Zyra has the advantage against Seraphine with a 63.4% win rate versus 36.6%. Zyra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Seraphine do against Zyra in the late game?

In the late game, Seraphine takes over the Seraphine vs Zyra matchup with a 54.8% win rate compared to 45.2%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Seraphine vs Zyra matchup?

Zyra wins the matchup against Seraphine with a 52.4% win rate in League of Legends patch 26.7. The 4.9 percentage point advantage means Zyra is moderately favored in this lane matchup based on 103 games analyzed.

What is the best Seraphine build against Zyra?

The best Seraphine build against Zyra includes Echoes of Helia, Rylai's Crystal Scepter, Diadem of Songs with Ionian Boots of Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Seraphine runes against Zyra?

The best Seraphine runes against Zyra use the Sorcery primary tree with Inspiration secondary. This rune setup achieves a 53.3% win rate in the Seraphine vs Zyra matchup. See the full rune breakdown in the matchup comparison above.

Does Seraphine counter Zyra?

No, Seraphine struggles against Zyra with only a 47.6% win rate. Zyra has the advantage in this matchup. Seraphine players should focus on safe farming and avoiding extended trades to minimize Zyra's lead.

How do I play Seraphine against Zyra?

When playing Seraphine against Zyra, play cautiously and avoid Zyra's power spikes. Focus on safe farming — you outscale Zyra in the late game. Use the matchup-specific build and runes above to optimize your chances.