Anivia - League of Legends Champion
Win Rate
49.7%
Pick Rate
1.9%

Aniviavs Senna

CMage
Patch26.4
Matches1,089,240
LaneAll Lanes
TierAll Tiers
Last UpdatedMar 3, 2026
MethodologyData Methodology

Anivia vs Senna is a decisive matchup in LoL patch 26.4. Senna wins with a 52.9% win rate (+5.9%) over Anivia based on 34 games. Anivia wins the early laning phase while Senna scales better into the late game. Below you'll find the best Anivia build, runes, laning stats, and strategies for the Anivia vs Senna matchup.

Anivia Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Anivia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Senna - 47.1% win rateSenna(47.1%)
Anivia - 47.1% win rate in this matchup
Anivia
47.1% WR
VS
Senna vs Anivia matchup - 52.9% win rate
Senna
52.9% WR

Who Wins the Anivia vs Senna Matchup?

Senna wins the Anivia vs Senna matchup
Winner
Senna
Matches: 34
47.1%
Win Rate
52.9%
2.6
CS / min
2.1
599
DMG / min
584
10,716
Gold / game
11,281
150
Heal / min
467
514
DMG Mitigated / min
350
1.7
CC / min
1.2
60.0%
Early Game WR
40.0%
41.7%
Late Game WR
58.3%

Anivia vs Senna Matchup Summary

The Anivia vs Senna matchup is a moderate matchup in League of Legends ranked play. Based on 34 recent matches analyzed, Senna wins with a 52.9% win rate compared to Anivia's 47.1%, giving Senna a 5.9 percentage point advantage. Game phase dynamics play a critical role here: Anivia controls the early laning stage, but Senna outscales as the game goes longer. The matchup shifts dramatically depending on game length — Anivia needs to press advantages before Senna reaches their power spikes, while Senna should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Anivia leads by 0.4s CC/min — a difference that heavily influences the outcome of trades and skirmishes. While Senna is slightly favored, Anivia can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Senna's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Anivia vs Senna Laning Phase Breakdown

Anivia wins the laning phase against Senna in League of Legends

Anivia is favored during the laning phase against Senna, winning 3 out of 5 key stat categories. Anivia holds advantages in farming, damage and crowd control, making them the stronger laner in this matchup.

Farming
2.6Anivia
2.1Senna
Anivia edges out Senna by 0.6 CS per minute — a moderate farming advantage that adds up to roughly 9 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Anivia.
Damage
599Anivia
584Senna
Damage output is virtually even between Anivia and Senna, with only 15 DMG/min separating them. Fights in this matchup are decided more by ability timing and positioning than raw damage numbers, making mechanical skill the deciding factor in trades.
Economy
10,716Anivia
11,281Senna
Senna earns 565 more gold per game than Anivia, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Senna slightly faster item completions.
Utility
1.7Anivia
1.2Senna
Anivia provides 0.4 seconds more crowd control per minute than Senna, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Anivia coordinate with their jungler and control the pace of skirmishes.
Sustain
664Anivia
817Senna
Senna vastly out-sustains Anivia, healing and mitigating 153 more damage per minute. This massive durability gap means Senna can absorb significant punishment and remain in lane while Anivia is forced to recall. Building grievous wounds early is essential for Anivia, and focusing on burst trade patterns rather than sustained fights is critical.

Best Anivia Build Against Senna

Sorcerer's Shoes is the optimal boots choice against Senna, providing the mobility and stats Anivia needs most in this matchup. The top-performing core items for Anivia against Senna are Rod of Ages, Liandry's Torment and Malignance. This combination gives Anivia an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 66.7% win rate across 3 games — well above average and making it the top item path against Senna. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Anivia vs Senna matchup.

Early Game vs Late Game

Early Game
Anivia
60.0%
+20.0% advantage
Anivia early game win rateAnivia60.0%
Senna early game win rateSenna40.0%
Late Game
Senna
58.3%
+16.7% advantage
Anivia late game win rateAnivia41.7%
Senna late game win rateSenna58.3%

Anivia dominates the early game (first 15 minutes) with a commanding 60.0% win rate — a 20.0 percentage point lead over Senna. This lopsided early game means Anivia can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Senna is far superior in the late game (25+ minutes), boasting a 58.3% win rate — 16.7 points above Anivia. Extended games heavily favor Senna, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Anivia must aggressively press their early advantage and close out the game before Senna reaches their scaling breakpoints. If Senna survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Anivia Runes Against Senna

Domination rune tree - Anivia primary runes vs SennaDomination
Electrocute - best Anivia rune vs SennaCheap Shot - best Anivia rune vs SennaGrisly Mementos - best Anivia rune vs SennaRelentless Hunter - best Anivia rune vs Senna
Sorcery rune tree - Anivia secondary runes vs SennaSorcery
Manaflow Band - best Anivia rune vs SennaScorch - best Anivia rune vs Senna
100.0% WR

The Domination and Sorcery rune setup gives Anivia the best tools to compete against Senna in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Anivia matchup data for League of Legends patch 26.4. The table below shows Anivia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Anivia build, runes, laning stats, and early vs late game analysis for that specific matchup.

Anivia matchup win rates and stats in League of Legends patch 26.4
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.39%2126.872911,35850.0%44.9%
46.47%1706.681711,89743.4%48.9%
41.96%1436.872711,75952.5%34.5%
47.41%1164.671011,36142.5%50.7%
47.71%1106.680511,87837.2%54.5%
50.00%1047.068711,36543.1%56.6%
50.50%1026.073411,65553.5%48.3%
62.07%876.786511,87271.8%54.2%
52.38%856.973411,31653.3%51.3%
44.44%836.978311,06948.7%40.5%
51.85%826.575311,53250.0%53.5%
46.67%756.588211,74047.1%46.3%
42.67%756.276311,57831.3%51.2%
52.86%706.371211,25853.3%52.5%
53.97%637.387512,06963.3%45.5%
44.44%636.579611,83534.6%51.4%
39.68%631.65249,15750.0%32.4%
54.10%616.584411,01350.0%60.0%
44.83%596.974712,43543.5%45.7%
61.02%597.182112,56060.7%61.3%
58.49%536.783211,76045.5%67.7%
44.23%534.970411,30847.8%41.4%
57.69%536.768411,46255.6%60.0%
57.69%526.470411,06745.8%67.9%
63.46%526.775111,89165.2%62.1%
50.00%467.091811,85550.0%50.0%
44.19%446.478511,68533.3%52.0%
61.36%446.785812,42264.7%59.3%
46.51%436.781112,46760.0%39.3%
45.24%431.959711,17735.7%50.0%
54.76%422.661610,68362.5%50.0%
45.24%427.085211,67352.4%38.1%
47.62%426.973911,35457.9%39.1%
43.59%392.161710,43530.8%50.0%
57.89%386.979311,20769.6%40.0%
45.71%356.872912,32053.3%40.0%
47.06%342.659910,71660.0%41.7%
65.63%344.384710,77282.3%46.7%
54.55%331.859810,18240.0%66.7%
42.42%333.36609,94953.3%33.3%
53.33%306.584013,38455.6%52.4%
66.67%306.580912,18460.0%70.0%
50.00%305.069910,02856.3%42.9%
62.07%296.278513,33383.3%56.5%
29.63%276.599212,33718.2%37.5%
55.56%276.878412,61772.7%43.8%
53.85%266.892211,37761.5%46.1%
44.00%256.864310,57453.9%33.3%
60.00%256.178212,02575.0%52.9%
48.00%252.15979,76153.9%41.7%
56.00%256.91,01913,29442.9%61.1%
52.00%252.25969,58150.0%53.3%
54.17%242.76858,47147.1%71.4%
50.00%246.11,01312,35744.4%53.3%
52.17%245.692511,88257.1%50.0%
62.50%246.974211,31572.7%53.9%
50.00%241.959710,46557.1%47.1%
70.83%243.458710,14450.0%81.3%
68.18%236.679512,19566.7%69.2%
47.83%236.677811,63361.5%30.0%
52.38%227.482712,21666.7%41.7%
50.00%221.84898,88945.5%54.5%
63.64%222.16059,82350.0%75.0%
50.00%225.070511,62357.1%46.7%
54.55%221.95948,77572.7%36.4%
59.09%221.859110,31471.4%53.3%
45.45%221.95089,98150.0%42.9%
26.32%196.765511,72125.0%27.3%
52.94%176.488212,95744.4%62.5%
75.00%166.679412,43283.3%70.0%
53.33%164.174911,90880.0%40.0%
43.75%165.778611,93250.0%33.3%
37.50%167.07209,81554.5%0.0%
81.25%166.47889,85370.0%100.0%
46.67%155.77259,59050.0%40.0%
46.67%155.56748,96854.5%25.0%
40.00%156.877313,14857.1%25.0%
42.86%146.485212,17880.0%22.2%
35.71%141.65439,7230.0%55.6%
35.71%142.14728,22950.0%16.7%
38.46%136.052710,24833.3%50.0%
38.46%135.483113,811100.0%27.3%
30.77%135.87307,58730.0%33.3%
33.33%127.180411,57640.0%28.6%
25.00%123.46779,80150.0%0.0%
58.33%126.498411,96471.4%40.0%
33.33%121.65229,58342.9%20.0%
45.45%116.779111,7280.0%71.4%
63.64%111.558610,75666.7%62.5%
54.55%115.376410,61628.6%100.0%
63.64%117.786013,18366.7%60.0%
36.36%115.670711,49366.7%25.0%
36.36%116.07149,9750.0%80.0%
36.36%116.370310,54220.0%50.0%
63.64%116.780212,32850.0%71.4%
70.00%102.86199,52833.3%85.7%
50.00%107.272810,47633.3%75.0%
30.00%106.799312,58366.7%14.3%
20.00%106.999711,61625.0%16.7%
70.00%107.069712,15183.3%50.0%
40.00%106.579111,00457.1%0.0%
66.67%107.279210,89583.3%33.3%
37.50%93.859710,19933.3%40.0%
33.33%96.865510,69220.0%50.0%
55.56%96.578113,81533.3%66.7%
44.44%92.368711,15925.0%60.0%
25.00%86.981411,74220.0%33.3%
62.50%82.455610,25260.0%66.7%
14.29%75.373911,1050.0%33.3%
57.14%76.883311,81650.0%66.7%
71.43%71.65268,33875.0%66.7%
66.67%66.781413,15550.0%75.0%
33.33%62.25859,29366.7%0.0%
33.33%64.44827,28940.0%0.0%
66.67%66.81,12014,638100.0%60.0%
66.67%67.176113,3430.0%100.0%
50.00%67.080212,13733.3%66.7%
33.33%67.194612,48850.0%25.0%
66.67%66.087611,03766.7%66.7%
50.00%65.783711,72050.0%50.0%
50.00%56.767411,95350.0%50.0%
80.00%57.373011,290100.0%50.0%
80.00%56.187315,369100.0%75.0%
80.00%56.51,05512,320100.0%66.7%
60.00%57.086613,182100.0%33.3%
60.00%56.36319,13450.0%100.0%
60.00%56.479114,209100.0%33.3%
20.00%57.187712,6340.0%25.0%
20.00%56.81,03815,65650.0%0.0%
40.00%55.986713,92150.0%33.3%
🔍

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Anivia vs Senna - Frequently Asked Questions

How does Anivia do against Senna in League of Legends?

Senna wins the Anivia vs Senna matchup with a 52.9% win rate compared to Anivia's 47.1%, a 5.9 percentage point difference. This data is based on 34 recent ranked games in patch 26.4.

How does Anivia do against Senna in the early game?

In the early game, Anivia has the advantage against Senna with a 60.0% win rate versus 40.0%. Anivia players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Anivia do against Senna in the late game?

In the late game, Senna takes over the Anivia vs Senna matchup with a 58.3% win rate compared to 41.7%. Senna scales better into team fights and objective contests after 25 minutes.

Who wins the Anivia vs Senna matchup?

Senna wins the matchup against Anivia with a 52.9% win rate in League of Legends patch 26.4. The 5.9 percentage point advantage means Senna is significantly favored in this lane matchup based on 34 games analyzed.

What is the best Anivia build against Senna?

The best Anivia build against Senna includes Rod of Ages, Liandry's Torment, Malignance with Sorcerer's Shoes. This build achieves a 66.7% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Anivia runes against Senna?

The best Anivia runes against Senna use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Anivia vs Senna matchup. See the full rune breakdown in the matchup comparison above.

Does Anivia counter Senna?

No, Anivia struggles against Senna with only a 47.1% win rate. Senna has the advantage in this matchup. Anivia players should focus on safe farming and avoiding extended trades to minimize Senna's lead.

How do I play Anivia against Senna?

When playing Anivia against Senna, play cautiously and avoid Senna's power spikes. Look for jungle assistance and team-dependent plays since Senna has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.