Caitlyn - League of Legends Champion
Win Rate
49.1%
Pick Rate
10.2%

Caitlynvs Karthus

DMarksman
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 23, 2026
MethodologyData Methodology

Caitlyn vs Karthus is a decisive matchup in LoL patch 26.14. Karthus wins with a 57.1% win rate (+14.3%) over Caitlyn based on 21 games. Caitlyn wins the early laning phase while Karthus scales better into the late game. Below you'll find the best Caitlyn build, runes, laning stats, and strategies for the Caitlyn vs Karthus matchup.

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Caitlyn Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Caitlyn performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Caitlyn - 42.9% win rate in this matchup
Caitlyn
42.9% WR
VS
Karthus vs Caitlyn matchup - 57.1% win rate
Karthus
57.1% WR

Who Wins the Caitlyn vs Karthus Matchup?

Karthus wins the Caitlyn vs Karthus matchup
Winner
Karthus
Matches: 21
42.9%
Win Rate
57.1%
6.9
CS / min
6.7
755
DMG / min
1,272
14,377
Gold / game
14,858
161
Heal / min
82
382
DMG Mitigated / min
404
0.5
CC / min
0.6
66.7%
Early Game WR
33.3%
33.3%
Late Game WR
66.7%

Caitlyn vs Karthus Matchup Summary

The Caitlyn vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 21 recent matches analyzed, Karthus wins with a 57.1% win rate compared to Caitlyn's 42.9%, giving Karthus a 14.3 percentage point advantage. Game phase dynamics play a critical role here: Caitlyn controls the early laning stage, but Karthus outscales as the game goes longer. The matchup shifts dramatically depending on game length — Caitlyn needs to press advantages before Karthus reaches their power spikes, while Karthus should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in damage output, where Karthus leads by 516 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Karthus has a strong advantage in this matchup. Caitlyn players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Karthus overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Caitlyn vs Karthus Laning Phase Breakdown

Karthus wins the laning phase against Caitlyn in League of Legends

Karthus is favored during the laning phase against Caitlyn, winning 3 out of 5 key stat categories. Karthus holds advantages in damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
6.9Caitlyn
6.7Karthus
Caitlyn and Karthus farm at nearly identical rates in this matchup, with only a 0.2 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
755Caitlyn
1,272Karthus
Karthus heavily out-damages Caitlyn by 516 DMG/min, dominating both short trades and all-in fights. Caitlyn should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
14,377Caitlyn
14,858Karthus
Karthus earns 481 more gold per game than Caitlyn, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Karthus slightly faster item completions.
Utility
0.5Caitlyn
0.6Karthus
Both Caitlyn and Karthus provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
543Caitlyn
486Karthus
Caitlyn heals and mitigates 57 more damage per minute than Karthus, providing moderate extra durability. This sustain edge allows Caitlyn to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Karthus.

Early Game vs Late Game

Early Game
Caitlyn
66.7%
+33.3% advantage
Caitlyn early game win rateCaitlyn66.7%
Karthus early game win rateKarthus33.3%
Late Game
Karthus
66.7%
+33.3% advantage
Caitlyn late game win rateCaitlyn33.3%
Karthus late game win rateKarthus66.7%

Caitlyn dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Karthus. This lopsided early game means Caitlyn can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Karthus is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Caitlyn. Extended games heavily favor Karthus, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Caitlyn must aggressively press their early advantage and close out the game before Karthus reaches their scaling breakpoints. If Karthus survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Caitlyn Runes Against Karthus

Precision rune tree - Caitlyn primary runes vs KarthusPrecision
Lethal Tempo - best Caitlyn rune vs KarthusPresence of Mind - best Caitlyn rune vs KarthusLegend: Bloodline - best Caitlyn rune vs KarthusCoup de Grace - best Caitlyn rune vs Karthus
Sorcery rune tree - Caitlyn secondary runes vs KarthusSorcery
Absolute Focus - best Caitlyn rune vs KarthusGathering Storm - best Caitlyn rune vs Karthus
27.3% WR

The Precision and Sorcery rune setup gives Caitlyn the best tools to compete against Karthus in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Caitlyn matchup data for League of Legends patch 26.14. The table below shows Caitlyn's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Caitlyn build, runes, laning stats, and early vs late game analysis for that specific matchup.

Caitlyn matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.21%1,1996.583212,79950.4%45.1%
45.58%9616.686113,23038.9%49.4%
53.57%7716.787812,73852.1%54.7%
52.57%6436.785312,97849.2%54.9%
51.16%6026.887813,11551.9%50.7%
52.78%4136.686612,83752.6%52.9%
58.74%4127.093213,09054.4%62.3%
50.87%3446.991412,92752.2%49.7%
46.58%3076.790513,25851.2%43.4%
50.35%2886.887313,68650.5%50.3%
44.80%2796.485313,25150.0%41.7%
41.67%2526.777012,40328.7%49.4%
51.19%2526.690513,02652.0%50.6%
44.35%2306.887112,44039.6%48.7%
50.70%2156.680712,68552.4%49.6%
51.17%2136.685212,84057.0%47.8%
50.00%1906.987013,40042.6%54.1%
52.75%1826.886412,41347.5%56.9%
43.26%1786.685412,79941.3%44.4%
56.18%1786.889013,02447.4%62.8%
47.53%1626.780312,26434.3%56.8%
52.11%1426.885813,35049.1%54.0%
49.14%1167.186312,59356.6%42.9%
50.00%906.790313,73050.0%50.0%
51.14%886.986813,39551.6%50.9%
43.68%876.786913,54644.4%43.3%
31.76%856.575611,75722.2%38.8%
48.10%796.495812,83351.9%46.1%
50.00%786.484712,01939.4%57.8%
42.11%766.677213,76520.0%47.5%
45.45%666.579412,15152.0%41.5%
44.64%566.586612,66752.0%38.7%
43.75%487.276812,18352.6%37.9%
57.45%476.994414,12555.0%59.3%
42.55%476.467211,40528.6%53.9%
38.10%427.079012,64630.8%41.4%
34.48%296.386112,19438.5%31.3%
52.00%255.977812,14355.6%50.0%
56.00%256.891413,26642.9%61.1%
47.83%236.785011,59957.1%43.8%
57.14%216.386314,03150.0%60.0%
42.86%216.975514,37766.7%33.3%
35.00%205.91,07813,94125.0%41.7%
33.33%185.367210,09930.0%37.5%
29.41%176.484113,8780.0%41.7%
40.00%156.078711,20040.0%40.0%
35.71%147.196316,3440.0%41.7%
46.15%136.593910,80342.9%50.0%
30.77%136.286615,14833.3%30.0%
58.33%126.974811,87080.0%42.9%
63.64%116.081412,54150.0%71.4%
55.56%97.01,03312,04350.0%60.0%
66.67%97.31,05116,451100.0%62.5%
44.44%96.51,03113,70925.0%60.0%
75.00%87.21,07515,19666.7%80.0%
25.00%85.567412,3070.0%33.3%
50.00%86.070411,01333.3%60.0%
75.00%87.062212,89366.7%80.0%
42.86%76.580913,91333.3%50.0%
14.29%76.184011,9200.0%20.0%
50.00%66.292910,726100.0%25.0%
33.33%65.71,38214,1740.0%50.0%
16.67%65.679314,3110.0%25.0%
83.33%65.91,20614,810100.0%75.0%
100.00%66.41,02515,942100.0%100.0%
20.00%56.264913,7490.0%20.0%
60.00%57.282211,92633.3%100.0%
60.00%56.31,18417,823100.0%50.0%
20.00%56.173210,1710.0%50.0%

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Caitlyn vs Karthus - Frequently Asked Questions

How does Caitlyn do against Karthus in League of Legends?

Karthus wins the Caitlyn vs Karthus matchup with a 57.1% win rate compared to Caitlyn's 42.9%, a 14.3 percentage point difference. This data is based on 21 recent ranked games in patch 26.14.

How does Caitlyn do against Karthus in the early game?

In the early game, Caitlyn has the advantage against Karthus with a 66.7% win rate versus 33.3%. Caitlyn players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Caitlyn do against Karthus in the late game?

In the late game, Karthus takes over the Caitlyn vs Karthus matchup with a 66.7% win rate compared to 33.3%. Karthus scales better into team fights and objective contests after 25 minutes.

Who wins the Caitlyn vs Karthus matchup?

Karthus wins the matchup against Caitlyn with a 57.1% win rate in League of Legends patch 26.14. The 14.3 percentage point advantage means Karthus is significantly favored in this lane matchup based on 21 games analyzed.

What is the best Caitlyn build against Karthus?

The best Caitlyn build against Karthus includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Caitlyn runes against Karthus?

The best Caitlyn runes against Karthus use the Precision primary tree with Sorcery secondary. This rune setup achieves a 27.3% win rate in the Caitlyn vs Karthus matchup. See the full rune breakdown in the matchup comparison above.

Does Caitlyn counter Karthus?

No, Caitlyn struggles against Karthus with only a 42.9% win rate. Karthus has the advantage in this matchup. Caitlyn players should focus on safe farming and avoiding extended trades to minimize Karthus's lead.

How do I play Caitlyn against Karthus?

When playing Caitlyn against Karthus, play cautiously and avoid Karthus's power spikes. Look for jungle assistance and team-dependent plays since Karthus has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.