Karthus - League of Legends Champion
Win Rate
50.0%
Pick Rate
1.1%

Karthusvs Caitlyn

CMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 5, 2026
MethodologyData Methodology

Karthus vs Caitlyn is a decisive matchup in LoL patch 26.11. Karthus wins with a 64.4% win rate (+28.9%) over Caitlyn based on 45 games. Karthus holds the advantage in both the early and late game. Below you'll find the best Karthus build, runes, laning stats, and strategies for the Karthus vs Caitlyn matchup.

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Karthus Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Karthus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karthus - 64.4% win rate in this matchup
Karthus
64.4% WR
VS
Caitlyn vs Karthus matchup - 35.6% win rate
Caitlyn
35.6% WR

Who Wins the Karthus vs Caitlyn Matchup?

Karthus wins the Karthus vs Caitlyn matchup
Winner
Karthus
Matches: 45
64.4%
Win Rate
35.6%
6.5
CS / min
6.7
1,326
DMG / min
866
16,022
Gold / game
15,027
88
Heal / min
185
414
DMG Mitigated / min
396
0.6
CC / min
0.7
86.7%
Early Game WR
13.3%
53.3%
Late Game WR
46.7%

Karthus vs Caitlyn Matchup Summary

The Karthus vs Caitlyn matchup is a decisive matchup in League of Legends ranked play. Based on 45 recent matches analyzed, Karthus wins with a 64.4% win rate compared to Caitlyn's 35.6%, giving Karthus a 28.9 percentage point advantage. Karthus dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Caitlyn players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in damage output, where Karthus leads by 460 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Karthus players can confidently pick into Caitlyn and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Caitlyn away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Karthus vs Caitlyn Laning Phase Breakdown

Caitlyn wins the laning phase against Karthus in League of Legends

Caitlyn is favored during the laning phase against Karthus, winning 3 out of 5 key stat categories. Caitlyn holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.5Karthus
6.7Caitlyn
Karthus and Caitlyn farm at nearly identical rates in this matchup, with only a 0.2 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
1,326Karthus
866Caitlyn
Karthus heavily out-damages Caitlyn by 460 DMG/min, dominating both short trades and all-in fights. Caitlyn should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
16,022Karthus
15,027Caitlyn
Karthus generates a commanding 995 more gold per game than Caitlyn. This substantial economic advantage means Karthus consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Caitlyn should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.6Karthus
0.7Caitlyn
Both Karthus and Caitlyn provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
502Karthus
581Caitlyn
Caitlyn heals and mitigates 79 more damage per minute than Karthus, providing moderate extra durability. This sustain edge allows Caitlyn to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Karthus.

Early Game vs Late Game

Early Game
Karthus
86.7%
+73.3% advantage
Karthus early game win rateKarthus86.7%
Caitlyn early game win rateCaitlyn13.3%
Late Game
Karthus
53.3%
+6.7% advantage
Karthus late game win rateKarthus53.3%
Caitlyn late game win rateCaitlyn46.7%

Karthus dominates the early game (first 15 minutes) with a commanding 86.7% win rate — a 73.3 percentage point lead over Caitlyn. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Karthus is far superior in the late game (25+ minutes), boasting a 53.3% win rate — 6.7 points above Caitlyn. Extended games heavily favor Karthus, whose kit and scaling make them a dominant force in team fights and objective control.

Karthus holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Caitlyn players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Karthus Runes Against Caitlyn

Sorcery rune tree - Karthus primary runes vs CaitlynSorcery
Deathfire Touch - best Karthus rune vs CaitlynAxiom Arcanist - best Karthus rune vs CaitlynTranscendence - best Karthus rune vs CaitlynScorch - best Karthus rune vs Caitlyn
Precision rune tree - Karthus secondary runes vs CaitlynPrecision
Presence of Mind - best Karthus rune vs CaitlynLast Stand - best Karthus rune vs Caitlyn
100.0% WR

Running Sorcery primary with Precision secondary allows Karthus to press their advantage against Caitlyn, amplifying the strengths that make this a favorable matchup.


Karthus matchup data for League of Legends patch 26.11. The table below shows Karthus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karthus build, runes, laning stats, and early vs late game analysis for that specific matchup.

Karthus matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.09%551.41,03012,95747.8%50.0%
43.64%551.71,17013,03740.0%46.7%
45.10%511.61,05713,34631.8%55.2%
59.18%496.31,29113,60950.0%65.5%
52.08%481.51,25914,65547.1%54.8%
42.22%451.51,01713,07143.8%41.4%
37.78%451.31,02712,76840.9%34.8%
64.44%456.51,32616,02286.7%53.3%
50.00%426.61,19713,07066.7%33.3%
43.59%396.31,21513,23850.0%36.8%
57.89%381.41,26313,76053.3%60.9%
47.37%381.51,14413,40237.5%54.5%
34.21%381.91,06712,86740.0%30.4%
43.24%371.81,21213,46357.1%34.8%
38.24%347.01,24713,84233.3%42.1%
46.88%321.81,14612,84538.5%52.6%
43.33%301.81,29414,56958.3%33.3%
55.17%296.11,20312,39066.7%42.9%
46.43%281.41,03012,47453.3%38.5%
57.14%286.61,42315,21450.0%62.5%
40.74%271.31,33515,99216.7%47.6%
28.00%251.81,16313,29530.0%26.7%
66.67%241.61,14614,33775.0%58.3%
45.45%221.51,30714,90550.0%44.4%
66.67%212.21,20113,57277.8%58.3%
55.00%201.61,26713,96860.0%50.0%
68.42%195.61,49616,092100.0%60.0%
63.16%191.31,11614,40962.5%63.6%
38.89%181.51,44814,53542.9%36.4%
55.56%186.41,27613,45466.7%44.4%
72.22%185.11,12111,32260.0%87.5%
35.29%171.51,05612,45536.4%33.3%
52.94%171.31,37015,16157.1%50.0%
76.47%176.51,26315,48280.0%75.0%
47.06%171.596012,24444.4%50.0%
52.94%176.51,33013,71966.7%45.5%
43.75%161.41,24415,49750.0%41.7%
56.25%161.31,08013,22180.0%45.5%
53.33%155.41,37313,67875.0%45.5%
35.71%141.61,23913,56744.4%20.0%
28.57%146.71,35911,93450.0%12.5%
42.86%142.41,25014,77740.0%44.4%
50.00%141.61,08215,54125.0%60.0%
69.23%136.51,30513,96557.1%83.3%
61.54%136.51,25612,93960.0%62.5%
53.85%132.51,05212,27675.0%44.4%
58.33%125.91,02710,26957.1%60.0%
83.33%121.31,22913,18380.0%85.7%
50.00%125.41,34014,96775.0%37.5%
45.45%111.41,03113,14557.1%25.0%
72.73%111.61,02712,997100.0%57.1%
27.27%115.91,13213,2320.0%42.9%
30.00%103.21,05913,47225.0%33.3%
70.00%107.41,27115,568100.0%57.1%
70.00%102.91,14415,271100.0%62.5%
50.00%107.21,13812,21650.0%50.0%
40.00%102.91,37615,5780.0%44.4%
55.56%95.51,26613,15150.0%60.0%
33.33%94.992710,92520.0%50.0%
44.44%96.21,07210,46733.3%66.7%
55.56%93.31,21214,875100.0%42.9%
55.56%91.41,25215,076100.0%42.9%
77.78%92.91,16514,15366.7%83.3%
33.33%92.11,19513,83433.3%33.3%
87.50%81.31,11314,33780.0%100.0%
25.00%81.31,28513,22250.0%16.7%
87.50%86.41,18214,46450.0%100.0%
75.00%81.71,65016,96550.0%83.3%
75.00%86.71,19715,02375.0%75.0%
62.50%82.099113,519100.0%50.0%
37.50%81.799613,5240.0%50.0%
57.14%76.31,63217,174100.0%50.0%
42.86%72.91,10811,95025.0%66.7%
14.29%71.190712,62625.0%0.0%
71.43%76.91,20214,28450.0%80.0%
85.71%75.51,33217,1080.0%85.7%
42.86%74.11,21013,9640.0%50.0%
28.57%76.01,44213,3670.0%40.0%
57.14%77.01,42713,69033.3%75.0%
57.14%72.41,12412,10740.0%100.0%
85.71%71.01,06214,10450.0%100.0%
50.00%67.11,38812,74350.0%50.0%
33.33%66.81,14411,4860.0%66.7%
66.67%64.21,44015,135100.0%60.0%
33.33%62.39659,7790.0%50.0%
33.33%62.51,07412,12050.0%0.0%
33.33%66.61,31611,4480.0%66.7%
16.67%65.81,30313,2700.0%25.0%
50.00%62.51,43716,7350.0%75.0%
20.00%56.31,40913,9390.0%33.3%
40.00%55.37986,5180.0%100.0%
40.00%51.11,41814,8040.0%50.0%
40.00%53.41,19015,0350.0%50.0%
60.00%54.61,65613,73266.7%50.0%
80.00%56.71,33110,47066.7%100.0%
60.00%52.01,29214,405100.0%50.0%
20.00%56.01,20610,84633.3%0.0%
40.00%56.71,01212,7100.0%50.0%
40.00%56.31,48213,690100.0%25.0%
60.00%55.91,40013,38366.7%50.0%
40.00%56.51,1899,67725.0%100.0%

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Karthus vs Caitlyn - Frequently Asked Questions

How does Karthus do against Caitlyn in League of Legends?

Karthus wins the Karthus vs Caitlyn matchup with a 64.4% win rate compared to Caitlyn's 35.6%, a 28.9 percentage point difference. This data is based on 45 recent ranked games in patch 26.11.

How does Karthus do against Caitlyn in the early game?

In the early game, Karthus has the advantage against Caitlyn with a 86.7% win rate versus 13.3%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Karthus do against Caitlyn in the late game?

In the late game, Karthus takes over the Karthus vs Caitlyn matchup with a 53.3% win rate compared to 46.7%. Karthus scales better into team fights and objective contests after 25 minutes.

Who wins the Karthus vs Caitlyn matchup?

Karthus wins the matchup against Caitlyn with a 64.4% win rate in League of Legends patch 26.11. The 28.9 percentage point advantage means Karthus is significantly favored in this lane matchup based on 45 games analyzed.

What is the best Karthus build against Caitlyn?

The best Karthus build against Caitlyn includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Karthus runes against Caitlyn?

The best Karthus runes against Caitlyn use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Karthus vs Caitlyn matchup. See the full rune breakdown in the matchup comparison above.

Does Karthus counter Caitlyn?

Yes, Karthus has a favorable matchup against Caitlyn with a 64.4% win rate. Karthus strongly counters Caitlyn in lane based on current patch 26.11 data.

How do I play Karthus against Caitlyn?

When playing Karthus against Caitlyn, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.