Karthus - League of Legends Champion
Win Rate
49.3%
Pick Rate
1.3%

Karthusvs Caitlyn

DMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 21, 2026
MethodologyData Methodology

Karthus vs Caitlyn is a decisive matchup in LoL patch 26.7. Karthus wins with a 59.5% win rate (+18.9%) over Caitlyn based on 37 games. Karthus holds the advantage in both the early and late game. Below you'll find the best Karthus build, runes, laning stats, and strategies for the Karthus vs Caitlyn matchup.

Karthus Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Karthus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Caitlyn - 59.5% win rateCaitlyn(59.5%)
Karthus - 59.5% win rate in this matchup
Karthus
59.5% WR
VS
Caitlyn vs Karthus matchup - 40.5% win rate
Caitlyn
40.5% WR

Who Wins the Karthus vs Caitlyn Matchup?

Karthus wins the Karthus vs Caitlyn matchup
Winner
Karthus
Matches: 37
59.5%
Win Rate
40.5%
6.8
CS / min
7.0
1,204
DMG / min
939
14,133
Gold / game
14,451
82
Heal / min
203
373
DMG Mitigated / min
388
0.6
CC / min
0.7
61.1%
Early Game WR
38.9%
57.9%
Late Game WR
42.1%

Karthus vs Caitlyn Matchup Summary

The Karthus vs Caitlyn matchup is a decisive matchup in League of Legends ranked play. Based on 37 recent matches analyzed, Karthus wins with a 59.5% win rate compared to Caitlyn's 40.5%, giving Karthus a 18.9 percentage point advantage. Karthus dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Caitlyn players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Caitlyn leads by 135 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Karthus players can confidently pick into Caitlyn and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Caitlyn away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Karthus vs Caitlyn Laning Phase Breakdown

Caitlyn wins the laning phase against Karthus in League of Legends

Caitlyn is favored during the laning phase against Karthus, winning 4 out of 5 key stat categories. Caitlyn holds advantages in farming, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.8Karthus
7.0Caitlyn
Karthus and Caitlyn farm at nearly identical rates in this matchup, with only a 0.3 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
1,204Karthus
939Caitlyn
Karthus heavily out-damages Caitlyn by 265 DMG/min, dominating both short trades and all-in fights. Caitlyn should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
14,133Karthus
14,451Caitlyn
Caitlyn earns 318 more gold per game than Karthus, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Caitlyn slightly faster item completions.
Utility
0.6Karthus
0.7Caitlyn
Both Karthus and Caitlyn provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
455Karthus
590Caitlyn
Caitlyn heals and mitigates 135 more damage per minute than Karthus, providing moderate extra durability. This sustain edge allows Caitlyn to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Karthus.

Early Game vs Late Game

Early Game
Karthus
61.1%
+22.2% advantage
Karthus early game win rateKarthus61.1%
Caitlyn early game win rateCaitlyn38.9%
Late Game
Karthus
57.9%
+15.8% advantage
Karthus late game win rateKarthus57.9%
Caitlyn late game win rateCaitlyn42.1%

Karthus dominates the early game (first 15 minutes) with a commanding 61.1% win rate — a 22.2 percentage point lead over Caitlyn. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Karthus is far superior in the late game (25+ minutes), boasting a 57.9% win rate — 15.8 points above Caitlyn. Extended games heavily favor Karthus, whose kit and scaling make them a dominant force in team fights and objective control.

Karthus holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Caitlyn players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Karthus Runes Against Caitlyn

Domination rune tree - Karthus primary runes vs CaitlynDomination
Dark Harvest - best Karthus rune vs CaitlynCheap Shot - best Karthus rune vs CaitlynGrisly Mementos - best Karthus rune vs CaitlynUltimate Hunter - best Karthus rune vs Caitlyn
Precision rune tree - Karthus secondary runes vs CaitlynPrecision
Last Stand - best Karthus rune vs CaitlynPresence of Mind - best Karthus rune vs Caitlyn
60.0% WR

Running Domination primary with Precision secondary allows Karthus to press their advantage against Caitlyn, amplifying the strengths that make this a favorable matchup.


Karthus matchup data for League of Legends patch 26.7. The table below shows Karthus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karthus build, runes, laning stats, and early vs late game analysis for that specific matchup.

Karthus matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
48.78%411.51,24613,63464.7%37.5%
45.00%401.71,19914,67650.0%41.7%
37.84%371.81,20313,45342.9%34.8%
59.46%376.81,20414,13361.1%57.9%
58.33%361.41,18514,86346.1%65.2%
42.86%351.61,14713,92340.0%45.0%
44.12%341.41,12214,48658.3%36.4%
65.63%326.31,26613,64771.4%61.1%
50.00%281.61,25415,99971.4%42.9%
44.44%276.11,21913,94641.7%46.7%
59.26%276.01,24814,69160.0%58.8%
60.00%251.51,20814,13545.5%71.4%
63.64%222.01,41215,52085.7%53.3%
63.64%226.01,33115,66162.5%64.3%
57.89%191.21,11113,72737.5%72.7%
36.84%196.51,28014,54516.7%46.1%
42.11%191.51,29515,86340.0%42.9%
57.89%191.41,15014,33071.4%50.0%
47.06%176.41,29415,52850.0%46.1%
76.47%171.21,06613,39466.7%87.5%
47.06%171.81,19814,51350.0%46.1%
75.00%161.41,29814,71466.7%80.0%
56.25%161.51,14013,02250.0%62.5%
26.67%151.31,03412,14627.3%25.0%
33.33%152.11,14213,21320.0%40.0%
35.71%141.11,12013,85225.0%50.0%
38.46%131.21,08313,38916.7%57.1%
38.46%131.41,18614,42740.0%37.5%
23.08%132.21,01010,85522.2%25.0%
46.15%136.01,24613,80450.0%44.4%
53.85%137.11,16413,19242.9%66.7%
50.00%123.71,31914,92180.0%28.6%
50.00%121.21,22814,55325.0%62.5%
25.00%126.51,36414,04133.3%16.7%
83.33%121.41,23815,11766.7%88.9%
25.00%121.61,12615,19325.0%25.0%
66.67%127.31,53918,810100.0%60.0%
25.00%121.21,07613,8870.0%60.0%
50.00%121.31,03811,95450.0%50.0%
63.64%116.81,40515,26060.0%66.7%
63.64%112.91,09213,99266.7%62.5%
27.27%111.31,12512,25020.0%33.3%
18.18%111.51,18312,73025.0%14.3%
45.45%116.71,23014,91440.0%50.0%
70.00%105.91,26912,68760.0%80.0%
60.00%107.01,16813,68960.0%60.0%
60.00%101.41,38813,38660.0%60.0%
70.00%107.11,33314,53075.0%66.7%
33.33%97.31,21213,57820.0%50.0%
44.44%93.899013,717100.0%28.6%
22.22%96.81,08812,89120.0%25.0%
66.67%91.61,56915,98675.0%60.0%
66.67%91.81,22714,33780.0%50.0%
33.33%94.81,07213,64425.0%40.0%
50.00%86.71,22114,59460.0%33.3%
37.50%81.81,33816,668100.0%28.6%
42.86%72.11,10612,56733.3%50.0%
42.86%72.21,17211,38060.0%0.0%
42.86%72.01,37413,47750.0%33.3%
42.86%77.21,12512,97033.3%50.0%
71.43%75.71,05413,5520.0%100.0%
71.43%71.21,49615,8850.0%83.3%
14.29%72.91,23213,7160.0%33.3%
57.14%72.01,19112,95466.7%50.0%
42.86%72.11,19315,03550.0%40.0%
85.71%71.61,34617,646100.0%80.0%
57.14%72.81,23515,411100.0%40.0%
50.00%66.91,27912,34425.0%100.0%
66.67%61.31,38414,20166.7%66.7%
66.67%61.396311,486100.0%50.0%
33.33%65.41,55214,5320.0%33.3%
33.33%62.481311,29650.0%0.0%
66.67%64.01,15114,6630.0%80.0%
16.67%61.41,19215,1100.0%20.0%
50.00%61.61,26817,2400.0%60.0%
60.00%55.91,19113,24966.7%50.0%
40.00%51.61,10312,8790.0%66.7%
40.00%56.81,00311,9160.0%50.0%
60.00%55.11,47719,353100.0%50.0%
20.00%52.81,10312,98150.0%0.0%
60.00%53.17289,38375.0%0.0%
60.00%57.11,03414,8450.0%75.0%
20.00%58.21,15513,53650.0%0.0%
60.00%52.382213,48466.7%50.0%

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Karthus vs Caitlyn - Frequently Asked Questions

How does Karthus do against Caitlyn in League of Legends?

Karthus wins the Karthus vs Caitlyn matchup with a 59.5% win rate compared to Caitlyn's 40.5%, a 18.9 percentage point difference. This data is based on 37 recent ranked games in patch 26.7.

How does Karthus do against Caitlyn in the early game?

In the early game, Karthus has the advantage against Caitlyn with a 61.1% win rate versus 38.9%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Karthus do against Caitlyn in the late game?

In the late game, Karthus takes over the Karthus vs Caitlyn matchup with a 57.9% win rate compared to 42.1%. Karthus scales better into team fights and objective contests after 25 minutes.

Who wins the Karthus vs Caitlyn matchup?

Karthus wins the matchup against Caitlyn with a 59.5% win rate in League of Legends patch 26.7. The 18.9 percentage point advantage means Karthus is significantly favored in this lane matchup based on 37 games analyzed.

What is the best Karthus build against Caitlyn?

The best Karthus build against Caitlyn includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Karthus runes against Caitlyn?

The best Karthus runes against Caitlyn use the Domination primary tree with Precision secondary. This rune setup achieves a 60.0% win rate in the Karthus vs Caitlyn matchup. See the full rune breakdown in the matchup comparison above.

Does Karthus counter Caitlyn?

Yes, Karthus has a favorable matchup against Caitlyn with a 59.5% win rate. Karthus strongly counters Caitlyn in lane based on current patch 26.7 data.

How do I play Karthus against Caitlyn?

When playing Karthus against Caitlyn, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.