Cassiopeia - League of Legends Champion
Win Rate
50.3%
Pick Rate
0.7%

Cassiopeiavs Orianna

BMage
Patch26.5
Matches469,660
LaneAll Lanes
TierAll Tiers
Last UpdatedMar 12, 2026
MethodologyData Methodology

Cassiopeia vs Orianna is a decisive matchup in LoL patch 26.5. Orianna wins with a 66.7% win rate (+33.3%) over Cassiopeia based on 6 games. Orianna holds the advantage in both the early and late game. Below you'll find the best Cassiopeia build, runes, laning stats, and strategies for the Cassiopeia vs Orianna matchup.

Cassiopeia Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Cassiopeia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Orianna - 33.3% win rateOrianna(33.3%)
Cassiopeia - 33.3% win rate in this matchup
Cassiopeia
33.3% WR
VS
Orianna vs Cassiopeia matchup - 66.7% win rate
Orianna
66.7% WR

Who Wins the Cassiopeia vs Orianna Matchup?

Orianna wins the Cassiopeia vs Orianna matchup
Winner
Orianna
Matches: 6
33.3%
Win Rate
66.7%
7.4
CS / min
8.1
758
DMG / min
722
9,004
Gold / game
9,110
356
Heal / min
110
563
DMG Mitigated / min
522
0.9
CC / min
0.9
40.0%
Early Game WR
60.0%
0.0%
Late Game WR
100.0%

Cassiopeia vs Orianna Matchup Summary

The Cassiopeia vs Orianna matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Orianna wins with a 66.7% win rate compared to Cassiopeia's 33.3%, giving Orianna a 33.3 percentage point advantage. Orianna dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Cassiopeia players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Cassiopeia leads by 286 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Orianna has a strong advantage in this matchup. Cassiopeia players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Orianna overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Cassiopeia vs Orianna Laning Phase Breakdown

Orianna wins the laning phase against Cassiopeia in League of Legends

Orianna is favored during the laning phase against Cassiopeia, winning 3 out of 5 key stat categories. Orianna holds advantages in farming, gold income and crowd control, making them the stronger laner in this matchup.

Farming
7.4Cassiopeia
8.1Orianna
Orianna edges out Cassiopeia by 0.6 CS per minute — a moderate farming advantage that adds up to roughly 9 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Orianna.
Damage
758Cassiopeia
722Orianna
Cassiopeia deals 35 more champion damage per minute than Orianna. While noticeable in extended trades, this gap can be offset by Orianna choosing favorable fight windows, such as engaging when Cassiopeia's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
9,004Cassiopeia
9,110Orianna
Cassiopeia and Orianna generate nearly equal gold per game, with just a 106 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
0.9Cassiopeia
0.9Orianna
Both Cassiopeia and Orianna provide similar amounts of crowd control (0.0s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
919Cassiopeia
633Orianna
Cassiopeia vastly out-sustains Orianna, healing and mitigating 286 more damage per minute. This massive durability gap means Cassiopeia can absorb significant punishment and remain in lane while Orianna is forced to recall. Building grievous wounds early is essential for Orianna, and focusing on burst trade patterns rather than sustained fights is critical.

Best Cassiopeia Build Against Orianna

Swiftmarch is the optimal boots choice against Orianna, providing the mobility and stats Cassiopeia needs most in this matchup. The top-performing core items for Cassiopeia against Orianna are Cosmic Drive, Rylai's Crystal Scepter and Seraph's Embrace. This combination gives Cassiopeia an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Orianna. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Cassiopeia vs Orianna matchup.

Early Game vs Late Game

Early Game
Orianna
60.0%
+20.0% advantage
Cassiopeia early game win rateCassiopeia40.0%
Orianna early game win rateOrianna60.0%
Late Game
Orianna
100.0%
+100.0% advantage
Cassiopeia late game win rateCassiopeia0.0%
Orianna late game win rateOrianna100.0%

Orianna dominates the early game (first 15 minutes) with a commanding 60.0% win rate — a 20.0 percentage point lead over Cassiopeia. This lopsided early game means Orianna can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Orianna is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Cassiopeia. Extended games heavily favor Orianna, whose kit and scaling make them a dominant force in team fights and objective control.

Orianna holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Cassiopeia players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Cassiopeia Runes Against Orianna

Precision rune tree - Cassiopeia primary runes vs OriannaPrecision
Conqueror - best Cassiopeia rune vs OriannaTriumph - best Cassiopeia rune vs OriannaLegend: Haste - best Cassiopeia rune vs OriannaCut Down - best Cassiopeia rune vs Orianna
Resolve rune tree - Cassiopeia secondary runes vs OriannaResolve
Conditioning - best Cassiopeia rune vs OriannaOvergrowth - best Cassiopeia rune vs Orianna
100.0% WR

The Precision and Resolve rune setup gives Cassiopeia the best tools to compete against Orianna in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Cassiopeia matchup data for League of Legends patch 26.5. The table below shows Cassiopeia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Cassiopeia build, runes, laning stats, and early vs late game analysis for that specific matchup.

Cassiopeia matchup win rates and stats in League of Legends patch 26.5
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
40.54%376.770111,21235.3%45.0%
73.08%266.489211,87266.7%78.6%
47.37%196.77859,87666.7%14.3%
50.00%166.277611,82040.0%54.5%
81.25%166.790213,12485.7%77.8%
50.00%146.493014,221100.0%36.4%
35.71%146.785511,80622.2%60.0%
50.00%145.987612,81620.0%66.7%
30.77%136.580313,74133.3%30.0%
46.15%136.67449,90040.0%50.0%
46.15%136.268712,18975.0%33.3%
61.54%135.88009,47257.1%66.7%
58.33%127.288112,49933.3%66.7%
58.33%126.686111,17133.3%83.3%
50.00%127.688211,65871.4%20.0%
27.27%117.26329,69828.6%25.0%
40.00%106.464110,20260.0%20.0%
60.00%106.36539,46566.7%50.0%
33.33%96.81,11413,0380.0%42.9%
55.56%96.284611,12766.7%33.3%
66.67%96.888012,16766.7%66.7%
66.67%96.31,12714,36850.0%71.4%
50.00%86.267010,65333.3%60.0%
37.50%87.278810,15833.3%50.0%
50.00%85.671210,55966.7%40.0%
37.50%86.788511,60540.0%33.3%
25.00%85.377311,3690.0%33.3%
42.86%77.578110,70550.0%33.3%
83.33%66.91,07711,883100.0%50.0%
50.00%67.496412,15733.3%66.7%
66.67%67.11,10015,3690.0%66.7%
33.33%67.47589,00440.0%0.0%
66.67%66.584410,90475.0%50.0%
66.67%65.681611,28150.0%75.0%
83.33%66.764412,117100.0%75.0%
60.00%56.57529,95966.7%50.0%
100.00%57.078913,086100.0%100.0%
40.00%55.976010,76433.3%50.0%
40.00%56.595412,8600.0%100.0%
80.00%55.890413,292100.0%66.7%
40.00%55.556610,0730.0%66.7%
40.00%57.21,01411,92050.0%33.3%
100.00%26.89507,998100.0%0.0%

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Cassiopeia vs Orianna - Frequently Asked Questions

How does Cassiopeia do against Orianna in League of Legends?

Orianna wins the Cassiopeia vs Orianna matchup with a 66.7% win rate compared to Cassiopeia's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.5.

How does Cassiopeia do against Orianna in the early game?

In the early game, Orianna has the advantage against Cassiopeia with a 60.0% win rate versus 40.0%. Orianna players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Cassiopeia do against Orianna in the late game?

In the late game, Orianna takes over the Cassiopeia vs Orianna matchup with a 100.0% win rate compared to 0.0%. Orianna scales better into team fights and objective contests after 25 minutes.

Who wins the Cassiopeia vs Orianna matchup?

Orianna wins the matchup against Cassiopeia with a 66.7% win rate in League of Legends patch 26.5. The 33.3 percentage point advantage means Orianna is significantly favored in this lane matchup based on 6 games analyzed.

What is the best Cassiopeia build against Orianna?

The best Cassiopeia build against Orianna includes Cosmic Drive, Rylai's Crystal Scepter, Seraph's Embrace with Swiftmarch. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Cassiopeia runes against Orianna?

The best Cassiopeia runes against Orianna use the Precision primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Cassiopeia vs Orianna matchup. See the full rune breakdown in the matchup comparison above.

Does Cassiopeia counter Orianna?

No, Cassiopeia struggles against Orianna with only a 33.3% win rate. Orianna has the advantage in this matchup. Cassiopeia players should focus on safe farming and avoiding extended trades to minimize Orianna's lead.

How do I play Cassiopeia against Orianna?

When playing Cassiopeia against Orianna, play cautiously and avoid Orianna's power spikes. Look for jungle assistance and team-dependent plays since Orianna has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.