Cassiopeia - League of Legends Champion
Win Rate
46.3%
Pick Rate
0.9%

Cassiopeiavs Galio

FMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 10, 2026
MethodologyData Methodology

Cassiopeia vs Galio is a decisive matchup in LoL patch 26.11. Galio wins with a 72.7% win rate (+45.5%) over Cassiopeia based on 11 games. Galio holds the advantage in both the early and late game. Below you'll find the best Cassiopeia build, runes, laning stats, and strategies for the Cassiopeia vs Galio matchup.

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Cassiopeia Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Cassiopeia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Cassiopeia - 27.3% win rate in this matchup
Cassiopeia
27.3% WR
VS
Galio vs Cassiopeia matchup - 72.7% win rate
Galio
72.7% WR

Who Wins the Cassiopeia vs Galio Matchup?

Galio wins the Cassiopeia vs Galio matchup
Winner
Galio
Matches: 11
27.3%
Win Rate
72.7%
6.4
CS / min
5.8
746
DMG / min
757
11,720
Gold / game
11,384
239
Heal / min
142
617
DMG Mitigated / min
1,561
1.4
CC / min
1.5
20.0%
Early Game WR
80.0%
33.3%
Late Game WR
66.7%

Cassiopeia vs Galio Matchup Summary

The Cassiopeia vs Galio matchup is a decisive matchup in League of Legends ranked play. Based on 11 recent matches analyzed, Galio wins with a 72.7% win rate compared to Cassiopeia's 27.3%, giving Galio a 45.5 percentage point advantage. Galio dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Cassiopeia players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Galio leads by 847 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Galio has a strong advantage in this matchup. Cassiopeia players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Galio overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Cassiopeia vs Galio Laning Phase Breakdown

Galio wins the laning phase against Cassiopeia in League of Legends

Galio is favored during the laning phase against Cassiopeia, winning 3 out of 5 key stat categories. Galio holds advantages in damage, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.4Cassiopeia
5.8Galio
Cassiopeia edges out Galio by 0.6 CS per minute — a moderate farming advantage that adds up to roughly 9 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Cassiopeia.
Damage
746Cassiopeia
757Galio
Damage output is virtually even between Cassiopeia and Galio, with only 12 DMG/min separating them. Fights in this matchup are decided more by ability timing and positioning than raw damage numbers, making mechanical skill the deciding factor in trades.
Economy
11,720Cassiopeia
11,384Galio
Cassiopeia earns 335 more gold per game than Galio, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Cassiopeia slightly faster item completions.
Utility
1.4Cassiopeia
1.5Galio
Both Cassiopeia and Galio provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
856Cassiopeia
1,703Galio
Galio vastly out-sustains Cassiopeia, healing and mitigating 847 more damage per minute. This massive durability gap means Galio can absorb significant punishment and remain in lane while Cassiopeia is forced to recall. Building grievous wounds early is essential for Cassiopeia, and focusing on burst trade patterns rather than sustained fights is critical.

Best Cassiopeia Build Against Galio

Swiftmarch is the optimal boots choice against Galio, providing the mobility and stats Cassiopeia needs most in this matchup. The top-performing core items for Cassiopeia against Galio are Rod of Ages, Rylai's Crystal Scepter and Seraph's Embrace. This combination gives Cassiopeia an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Cassiopeia vs Galio matchup.

Early Game vs Late Game

Early Game
Galio
80.0%
+60.0% advantage
Cassiopeia early game win rateCassiopeia20.0%
Galio early game win rateGalio80.0%
Late Game
Galio
66.7%
+33.3% advantage
Cassiopeia late game win rateCassiopeia33.3%
Galio late game win rateGalio66.7%

Galio dominates the early game (first 15 minutes) with a commanding 80.0% win rate — a 60.0 percentage point lead over Cassiopeia. This lopsided early game means Galio can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Galio is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Cassiopeia. Extended games heavily favor Galio, whose kit and scaling make them a dominant force in team fights and objective control.

Galio holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Cassiopeia players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Cassiopeia Runes Against Galio

Sorcery rune tree - Cassiopeia primary runes vs GalioSorcery
Deathfire Touch - best Cassiopeia rune vs GalioAxiom Arcanist - best Cassiopeia rune vs GalioTranscendence - best Cassiopeia rune vs GalioGathering Storm - best Cassiopeia rune vs Galio
Domination rune tree - Cassiopeia secondary runes vs GalioDomination
Ultimate Hunter - best Cassiopeia rune vs GalioCheap Shot - best Cassiopeia rune vs Galio
100.0% WR

The Sorcery and Domination rune setup gives Cassiopeia the best tools to compete against Galio in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Cassiopeia matchup data for League of Legends patch 26.11. The table below shows Cassiopeia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Cassiopeia build, runes, laning stats, and early vs late game analysis for that specific matchup.

Cassiopeia matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.54%616.383512,01164.0%36.1%
52.17%466.891312,15252.6%51.9%
48.65%376.789410,72047.4%50.0%
45.45%336.577611,98138.5%50.0%
46.88%326.685810,85138.1%63.6%
45.16%316.381210,57140.0%50.0%
51.61%317.196810,34854.5%44.4%
45.16%315.977112,56960.0%38.1%
64.52%316.792111,76266.7%62.5%
62.07%296.784312,31953.3%71.4%
42.86%286.974011,66242.9%42.9%
65.22%236.188411,04770.0%61.5%
34.78%236.178710,81440.0%30.8%
34.78%236.274110,91040.0%30.8%
31.82%226.581112,22950.0%21.4%
47.62%216.66699,96927.3%70.0%
66.67%217.095612,82280.0%62.5%
66.67%215.777111,60350.0%76.9%
60.00%206.872411,51850.0%70.0%
47.37%196.474910,42344.4%50.0%
63.16%196.489311,54970.0%55.6%
58.82%176.885811,94360.0%57.1%
52.94%176.592511,50037.5%66.7%
52.94%176.877410,92050.0%55.6%
82.35%176.789111,59488.9%75.0%
47.06%176.086412,19033.3%54.5%
37.50%166.688212,07240.0%36.4%
33.33%156.783512,4600.0%45.5%
66.67%155.781512,12850.0%77.8%
50.00%145.57939,64840.0%55.6%
71.43%146.671811,58380.0%66.7%
57.14%146.68888,74677.8%20.0%
42.86%147.096513,93966.7%25.0%
61.54%136.694413,07640.0%75.0%
33.33%127.391010,99440.0%28.6%
41.67%126.41,04012,89060.0%28.6%
33.33%126.679113,559100.0%27.3%
45.45%116.774611,84125.0%57.1%
18.18%116.278612,0890.0%28.6%
45.45%116.085011,82550.0%42.9%
63.64%115.790313,10766.7%62.5%
27.27%116.474611,72020.0%33.3%
36.36%116.596014,27050.0%28.6%
20.00%106.672610,42428.6%0.0%
40.00%106.398414,52250.0%37.5%
11.11%96.36538,76420.0%0.0%
44.44%96.987211,90440.0%50.0%
33.33%96.372412,71366.7%16.7%
44.44%96.41,27812,86950.0%42.9%
55.56%96.477611,32550.0%60.0%
55.56%96.588712,6850.0%62.5%
66.67%96.493714,897100.0%57.1%
25.00%87.380213,09033.3%20.0%
37.50%86.584312,21733.3%40.0%
57.14%75.989212,35666.7%50.0%
28.57%77.292414,4480.0%33.3%
42.86%76.277111,59450.0%33.3%
14.29%76.891611,0350.0%25.0%
71.43%76.086011,651100.0%50.0%
28.57%75.97388,49533.3%0.0%
66.67%66.592613,9850.0%100.0%
66.67%66.887313,102100.0%50.0%
33.33%66.863510,69750.0%25.0%
50.00%66.276512,03966.7%33.3%
50.00%66.765310,17766.7%33.3%
50.00%66.599812,680100.0%25.0%
60.00%56.367511,35250.0%66.7%
40.00%57.41,03413,86250.0%33.3%
20.00%58.176511,22633.3%0.0%
40.00%56.01,36511,71250.0%33.3%
40.00%55.87258,657100.0%25.0%
80.00%55.568410,127100.0%50.0%
20.00%57.31,04410,50033.3%0.0%
80.00%56.987910,244100.0%66.7%
20.00%56.27839,07950.0%0.0%
60.00%57.889613,847100.0%50.0%
40.00%55.071411,2290.0%50.0%

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Cassiopeia vs Galio - Frequently Asked Questions

How does Cassiopeia do against Galio in League of Legends?

Galio wins the Cassiopeia vs Galio matchup with a 72.7% win rate compared to Cassiopeia's 27.3%, a 45.5 percentage point difference. This data is based on 11 recent ranked games in patch 26.11.

How does Cassiopeia do against Galio in the early game?

In the early game, Galio has the advantage against Cassiopeia with a 80.0% win rate versus 20.0%. Galio players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Cassiopeia do against Galio in the late game?

In the late game, Galio takes over the Cassiopeia vs Galio matchup with a 66.7% win rate compared to 33.3%. Galio scales better into team fights and objective contests after 25 minutes.

Who wins the Cassiopeia vs Galio matchup?

Galio wins the matchup against Cassiopeia with a 72.7% win rate in League of Legends patch 26.11. The 45.5 percentage point advantage means Galio is significantly favored in this lane matchup based on 11 games analyzed.

What is the best Cassiopeia build against Galio?

The best Cassiopeia build against Galio includes Rod of Ages, Rylai's Crystal Scepter, Seraph's Embrace with Swiftmarch. Check the matchup breakdown above for the full item path and build order.

What are the best Cassiopeia runes against Galio?

The best Cassiopeia runes against Galio use the Sorcery primary tree with Domination secondary. This rune setup achieves a 100.0% win rate in the Cassiopeia vs Galio matchup. See the full rune breakdown in the matchup comparison above.

Does Cassiopeia counter Galio?

No, Cassiopeia struggles against Galio with only a 27.3% win rate. Galio has the advantage in this matchup. Cassiopeia players should focus on safe farming and avoiding extended trades to minimize Galio's lead.

How do I play Cassiopeia against Galio?

When playing Cassiopeia against Galio, play cautiously and avoid Galio's power spikes. Look for jungle assistance and team-dependent plays since Galio has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.