Karthus - League of Legends Champion
Win Rate
52.9%
Pick Rate
0.9%

Karthusvs Diana

SMage
Patch26.14
Matches226,800
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Karthus vs Diana is a decisive matchup in LoL patch 26.14. Diana wins with a 60.0% win rate (+20.0%) over Karthus based on 5 games. Karthus wins the early laning phase while Diana scales better into the late game. Below you'll find the best Karthus build, runes, laning stats, and strategies for the Karthus vs Diana matchup.

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Karthus Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Karthus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karthus - 40.0% win rate in this matchup
Karthus
40.0% WR
VS
Diana vs Karthus matchup - 60.0% win rate
Diana
60.0% WR

Who Wins the Karthus vs Diana Matchup?

Diana wins the Karthus vs Diana matchup
Winner
Diana
Matches: 5
40.0%
Win Rate
60.0%
0.9
CS / min
1.7
1,006
DMG / min
907
13,487
Gold / game
14,215
313
Heal / min
359
522
DMG Mitigated / min
1,508
0.6
CC / min
0.4
100.0%
Early Game WR
0.0%
25.0%
Late Game WR
75.0%

Karthus vs Diana Matchup Summary

The Karthus vs Diana matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Diana wins with a 60.0% win rate compared to Karthus's 40.0%, giving Diana a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Karthus controls the early laning stage, but Diana outscales as the game goes longer. The matchup shifts dramatically depending on game length — Karthus needs to press advantages before Diana reaches their power spikes, while Diana should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Diana leads by 1,033 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Diana has a strong advantage in this matchup. Karthus players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Diana overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Karthus vs Diana Laning Phase Breakdown

Diana wins the laning phase against Karthus in League of Legends

Diana is favored during the laning phase against Karthus, winning 3 out of 5 key stat categories. Diana holds advantages in farming, gold income and sustain, making them the stronger laner in this matchup.

Farming
0.9Karthus
1.7Diana
Diana edges out Karthus by 0.8 CS per minute — a moderate farming advantage that adds up to roughly 11 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Diana.
Damage
1,006Karthus
907Diana
Karthus heavily out-damages Diana by 99 DMG/min, dominating both short trades and all-in fights. Diana should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
13,487Karthus
14,215Diana
Diana earns 728 more gold per game than Karthus, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Diana slightly faster item completions.
Utility
0.6Karthus
0.4Diana
Both Karthus and Diana provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
834Karthus
1,867Diana
Diana vastly out-sustains Karthus, healing and mitigating 1,033 more damage per minute. This massive durability gap means Diana can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Karthus Build Against Diana

Sorcerer's Shoes is the optimal boots choice against Diana, providing the mobility and stats Karthus needs most in this matchup. The top-performing core items for Karthus against Diana are Liandry's Torment, Malignance and Blackfire Torch. This combination gives Karthus an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karthus vs Diana matchup.

Early Game vs Late Game

Early Game
Karthus
100.0%
+100.0% advantage
Karthus early game win rateKarthus100.0%
Diana early game win rateDiana0.0%
Late Game
Diana
75.0%
+50.0% advantage
Karthus late game win rateKarthus25.0%
Diana late game win rateDiana75.0%

Karthus dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Diana. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Diana is far superior in the late game (25+ minutes), boasting a 75.0% win rate — 50.0 points above Karthus. Extended games heavily favor Diana, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Karthus must aggressively press their early advantage and close out the game before Diana reaches their scaling breakpoints. If Diana survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Karthus Runes Against Diana

Domination rune tree - Karthus primary runes vs DianaDomination
Dark Harvest - best Karthus rune vs DianaCheap Shot - best Karthus rune vs DianaGrisly Mementos - best Karthus rune vs DianaUltimate Hunter - best Karthus rune vs Diana
Sorcery rune tree - Karthus secondary runes vs DianaSorcery
Axiom Arcanist - best Karthus rune vs DianaGathering Storm - best Karthus rune vs Diana
50.0% WR

The Domination and Sorcery rune setup gives Karthus the best tools to compete against Diana in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Karthus matchup data for League of Legends patch 26.14. The table below shows Karthus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karthus build, runes, laning stats, and early vs late game analysis for that specific matchup.

Karthus matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
64.71%171.61,30714,66766.7%64.3%
61.54%131.41,26816,483100.0%54.5%
38.46%131.71,13714,45550.0%33.3%
53.85%131.289010,32966.7%42.9%
66.67%127.01,13812,77283.3%50.0%
50.00%126.81,06013,5260.0%66.7%
66.67%121.21,22315,65033.3%77.8%
54.55%111.493212,47820.0%83.3%
54.55%111.31,25216,58775.0%42.9%
30.00%101.21,05811,5090.0%60.0%
77.78%96.91,58016,28933.3%100.0%
77.78%91.11,46516,15150.0%85.7%
50.00%81.41,36413,21550.0%50.0%
62.50%82.11,29411,38950.0%75.0%
75.00%81.71,19514,4940.0%85.7%
62.50%80.91,03211,64366.7%60.0%
0.00%81.29159,7700.0%0.0%
100.00%81.31,14611,386100.0%100.0%
71.43%75.91,21011,767100.0%60.0%
42.86%73.81,20014,23566.7%25.0%
50.00%61.81,15115,1510.0%60.0%
50.00%66.81,05414,8930.0%60.0%
33.33%65.61,01311,5230.0%100.0%
66.67%66.31,18714,6750.0%80.0%
40.00%50.91,14013,258100.0%25.0%
60.00%56.31,26410,41750.0%66.7%
40.00%50.91,00613,487100.0%25.0%
20.00%55.393411,78633.3%0.0%
40.00%51.21,37916,148100.0%25.0%
20.00%54.39793,1650.0%100.0%
60.00%51.31,04614,377100.0%50.0%
25.00%41.41,38413,8210.0%33.3%
25.00%42.31,12113,8860.0%33.3%
100.00%21.51,21814,599100.0%100.0%

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Karthus vs Diana - Frequently Asked Questions

How does Karthus do against Diana in League of Legends?

Diana wins the Karthus vs Diana matchup with a 60.0% win rate compared to Karthus's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.14.

How does Karthus do against Diana in the early game?

In the early game, Karthus has the advantage against Diana with a 100.0% win rate versus 0.0%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Karthus do against Diana in the late game?

In the late game, Diana takes over the Karthus vs Diana matchup with a 75.0% win rate compared to 25.0%. Diana scales better into team fights and objective contests after 25 minutes.

Who wins the Karthus vs Diana matchup?

Diana wins the matchup against Karthus with a 60.0% win rate in League of Legends patch 26.14. The 20.0 percentage point advantage means Diana is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Karthus build against Diana?

The best Karthus build against Diana includes Liandry's Torment, Malignance, Blackfire Torch with Sorcerer's Shoes. Check the matchup breakdown above for the full item path and build order.

What are the best Karthus runes against Diana?

The best Karthus runes against Diana use the Domination primary tree with Sorcery secondary. This rune setup achieves a 50.0% win rate in the Karthus vs Diana matchup. See the full rune breakdown in the matchup comparison above.

Does Karthus counter Diana?

No, Karthus struggles against Diana with only a 40.0% win rate. Diana has the advantage in this matchup. Karthus players should focus on safe farming and avoiding extended trades to minimize Diana's lead.

How do I play Karthus against Diana?

When playing Karthus against Diana, play cautiously and avoid Diana's power spikes. Look for jungle assistance and team-dependent plays since Diana has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.