
Dianavs Karthus
Diana vs Karthus is a decisive matchup in LoL patch 26.7. Karthus wins with a 76.5% win rate (+52.9%) over Diana based on 17 games. Karthus holds the advantage in both the early and late game. Below you'll find the best Diana build, runes, laning stats, and strategies for the Diana vs Karthus matchup.
Diana Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Diana performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Diana vs Karthus Matchup?

Diana vs Karthus Matchup Summary
The Diana vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 17 recent matches analyzed, Karthus wins with a 76.5% win rate compared to Diana's 23.5%, giving Karthus a 52.9 percentage point advantage. Karthus dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Diana players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Diana leads by 601 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Karthus has a strong advantage in this matchup. Diana players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Karthus overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Diana vs Karthus Laning Phase Breakdown
Karthus is favored during the laning phase against Diana, winning 4 out of 5 key stat categories. Karthus holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.
Best Diana Build Against Karthus
Sorcerer's Shoes is the optimal boots choice against Karthus, providing the mobility and stats Diana needs most in this matchup. The top-performing core items for Diana against Karthus are Riftmaker, Zhonya's Hourglass and Dusk and Dawn. This combination gives Diana an effective balance of damage, survivability, and utility for the matchup. This build has a 33.3% win rate across 3 games. While the overall matchup may be difficult, this item path gives Diana the best chance to compete against Karthus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Diana vs Karthus matchup.
Early Game vs Late Game
Karthus dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Diana. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Karthus is far superior in the late game (25+ minutes), boasting a 87.5% win rate — 75.0 points above Diana. Extended games heavily favor Karthus, whose kit and scaling make them a dominant force in team fights and objective control.
Karthus holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Diana players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Diana Runes Against Karthus
The Precision and Inspiration rune setup gives Diana the best tools to compete against Karthus in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Diana matchup data for League of Legends patch 26.7. The table below shows Diana's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Diana build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 51.89% | 106 | 6.0 | 896 | 12,542 | 57.5% | 47.5% | |
| 46.88% | 96 | 1.4 | 701 | 12,768 | 50.9% | 41.5% | |
| 44.21% | 95 | 1.3 | 685 | 12,661 | 54.4% | 34.7% | |
| 53.41% | 88 | 1.6 | 740 | 13,054 | 57.1% | 50.0% | |
| 40.48% | 84 | 5.8 | 860 | 12,466 | 47.1% | 36.0% | |
| 46.91% | 81 | 1.4 | 753 | 12,443 | 46.5% | 47.4% | |
| 51.90% | 79 | 6.1 | 817 | 13,192 | 63.3% | 44.9% | |
| 52.56% | 78 | 1.4 | 797 | 14,276 | 65.6% | 43.5% | |
| 48.00% | 75 | 4.3 | 850 | 11,976 | 51.2% | 43.8% | |
| 49.33% | 75 | 5.6 | 933 | 12,652 | 48.6% | 50.0% | |
| 37.84% | 74 | 1.5 | 753 | 13,378 | 43.8% | 33.3% | |
| 49.30% | 71 | 4.0 | 897 | 13,290 | 55.6% | 45.5% | |
| 56.52% | 69 | 1.7 | 779 | 13,481 | 54.8% | 57.9% | |
| 54.41% | 68 | 6.2 | 954 | 13,293 | 53.6% | 55.0% | |
| 49.23% | 65 | 5.9 | 881 | 12,352 | 54.8% | 44.1% | |
| 45.31% | 64 | 5.9 | 856 | 11,960 | 39.4% | 51.6% | |
| 46.03% | 63 | 6.2 | 865 | 12,223 | 42.9% | 48.6% | |
| 57.14% | 63 | 5.2 | 863 | 12,404 | 56.0% | 57.9% | |
| 56.14% | 57 | 6.0 | 998 | 12,198 | 48.3% | 64.3% | |
| 52.63% | 57 | 5.7 | 869 | 11,312 | 51.7% | 53.6% | |
| 51.79% | 56 | 5.8 | 897 | 12,437 | 61.3% | 40.0% | |
| 59.26% | 54 | 3.4 | 925 | 14,291 | 69.6% | 51.6% | |
| 37.74% | 53 | 1.4 | 850 | 12,885 | 38.5% | 37.0% | |
| 49.02% | 51 | 5.9 | 906 | 12,443 | 40.9% | 55.2% | |
| 43.48% | 46 | 6.0 | 795 | 11,944 | 47.6% | 40.0% | |
| 54.35% | 46 | 1.4 | 783 | 13,556 | 43.8% | 60.0% | |
| 50.00% | 44 | 6.0 | 883 | 11,931 | 63.6% | 36.4% | |
| 35.71% | 42 | 6.3 | 854 | 11,483 | 34.8% | 36.8% | |
| 53.66% | 41 | 1.6 | 801 | 12,955 | 45.8% | 64.7% | |
| 47.50% | 40 | 1.4 | 701 | 13,419 | 60.0% | 40.0% | |
| 41.03% | 39 | 3.9 | 823 | 12,599 | 41.2% | 40.9% | |
| 36.84% | 38 | 6.0 | 790 | 11,313 | 43.8% | 31.8% | |
| 59.46% | 37 | 1.2 | 742 | 13,677 | 70.6% | 50.0% | |
| 45.95% | 37 | 1.2 | 702 | 11,961 | 42.1% | 50.0% | |
| 57.14% | 35 | 6.0 | 933 | 13,408 | 84.6% | 40.9% | |
| 57.14% | 35 | 1.5 | 691 | 12,158 | 55.6% | 58.8% | |
| 52.94% | 34 | 1.1 | 704 | 12,144 | 60.0% | 47.4% | |
| 66.67% | 33 | 6.1 | 850 | 11,578 | 64.7% | 68.8% | |
| 78.79% | 33 | 5.6 | 1,001 | 12,837 | 76.9% | 80.0% | |
| 43.75% | 32 | 2.1 | 785 | 13,773 | 63.6% | 33.3% | |
| 46.88% | 32 | 1.3 | 735 | 12,193 | 50.0% | 41.7% | |
| 48.39% | 31 | 2.4 | 772 | 12,712 | 58.3% | 42.1% | |
| 41.94% | 31 | 1.6 | 871 | 12,547 | 41.2% | 42.9% | |
| 43.33% | 30 | 2.6 | 853 | 11,672 | 44.4% | 41.7% | |
| 63.33% | 30 | 5.4 | 869 | 12,216 | 50.0% | 72.2% | |
| 51.72% | 29 | 1.4 | 804 | 13,537 | 53.9% | 50.0% | |
| 48.28% | 29 | 1.6 | 909 | 12,536 | 43.8% | 53.9% | |
| 68.97% | 29 | 6.0 | 916 | 12,064 | 78.6% | 60.0% | |
| 57.14% | 28 | 1.4 | 852 | 14,019 | 60.0% | 55.6% | |
| 53.57% | 28 | 5.7 | 928 | 12,389 | 61.5% | 46.7% | |
| 48.15% | 27 | 1.4 | 778 | 14,610 | 54.5% | 43.8% | |
| 70.37% | 27 | 6.2 | 895 | 11,947 | 70.6% | 70.0% | |
| 48.15% | 27 | 1.3 | 720 | 12,155 | 58.3% | 40.0% | |
| 66.67% | 27 | 1.3 | 810 | 13,650 | 66.7% | 66.7% | |
| 34.62% | 26 | 1.8 | 778 | 13,339 | 46.1% | 23.1% | |
| 46.15% | 26 | 5.1 | 968 | 12,221 | 46.1% | 46.1% | |
| 44.00% | 25 | 1.3 | 768 | 13,357 | 50.0% | 38.5% | |
| 58.33% | 24 | 1.4 | 776 | 12,851 | 50.0% | 64.3% | |
| 54.17% | 24 | 6.0 | 967 | 14,328 | 50.0% | 56.3% | |
| 47.83% | 23 | 4.0 | 847 | 12,729 | 41.7% | 54.5% | |
| 45.45% | 22 | 5.9 | 974 | 13,214 | 62.5% | 35.7% | |
| 40.91% | 22 | 6.2 | 860 | 11,642 | 46.1% | 33.3% | |
| 61.90% | 21 | 2.1 | 726 | 11,963 | 75.0% | 44.4% | |
| 60.00% | 20 | 1.4 | 753 | 11,432 | 75.0% | 50.0% | |
| 50.00% | 20 | 2.3 | 771 | 13,596 | 50.0% | 50.0% | |
| 57.89% | 19 | 1.3 | 977 | 14,945 | 66.7% | 53.9% | |
| 42.11% | 19 | 1.3 | 682 | 12,096 | 44.4% | 40.0% | |
| 50.00% | 18 | 2.0 | 769 | 12,259 | 45.5% | 57.1% | |
| 44.44% | 18 | 1.7 | 868 | 13,915 | 71.4% | 27.3% | |
| 55.56% | 18 | 2.3 | 670 | 12,449 | 61.5% | 40.0% | |
| 52.94% | 17 | 4.7 | 829 | 13,106 | 42.9% | 60.0% | |
| 52.94% | 17 | 1.4 | 803 | 13,458 | 66.7% | 37.5% | |
| 23.53% | 17 | 1.1 | 648 | 12,158 | 33.3% | 12.5% | |
| 52.94% | 17 | 5.8 | 838 | 12,180 | 42.9% | 60.0% | |
| 50.00% | 16 | 5.8 | 1,015 | 13,104 | 50.0% | 50.0% | |
| 62.50% | 16 | 6.3 | 969 | 12,462 | 100.0% | 40.0% | |
| 66.67% | 15 | 6.2 | 927 | 14,084 | 50.0% | 69.2% | |
| 46.67% | 15 | 2.3 | 687 | 11,718 | 66.7% | 16.7% | |
| 26.67% | 15 | 4.3 | 717 | 11,868 | 28.6% | 25.0% | |
| 50.00% | 14 | 6.4 | 973 | 12,832 | 62.5% | 33.3% | |
| 42.86% | 14 | 4.7 | 837 | 12,242 | 44.4% | 40.0% | |
| 42.86% | 14 | 3.0 | 755 | 12,081 | 33.3% | 50.0% | |
| 42.86% | 14 | 1.1 | 778 | 10,999 | 40.0% | 50.0% | |
| 64.29% | 14 | 5.8 | 1,051 | 13,622 | 75.0% | 60.0% | |
| 35.71% | 14 | 3.1 | 795 | 12,923 | 40.0% | 33.3% | |
| 64.29% | 14 | 4.9 | 927 | 12,455 | 50.0% | 75.0% | |
| 69.23% | 13 | 5.0 | 939 | 12,965 | 100.0% | 60.0% | |
| 53.85% | 13 | 1.6 | 915 | 14,043 | 40.0% | 62.5% | |
| 76.92% | 13 | 6.2 | 922 | 9,860 | 80.0% | 66.7% | |
| 75.00% | 12 | 1.9 | 714 | 12,010 | 87.5% | 50.0% | |
| 66.67% | 12 | 1.8 | 720 | 12,105 | 57.1% | 80.0% | |
| 45.45% | 11 | 5.5 | 790 | 12,306 | 50.0% | 40.0% | |
| 36.36% | 11 | 4.8 | 1,035 | 13,430 | 66.7% | 25.0% | |
| 27.27% | 11 | 5.6 | 732 | 10,892 | 50.0% | 0.0% | |
| 63.64% | 11 | 5.6 | 1,149 | 12,888 | 40.0% | 83.3% | |
| 50.00% | 10 | 4.1 | 755 | 15,055 | 50.0% | 50.0% | |
| 44.44% | 9 | 1.6 | 813 | 13,797 | 33.3% | 50.0% | |
| 44.44% | 9 | 6.9 | 935 | 12,819 | 33.3% | 66.7% | |
| 66.67% | 9 | 1.1 | 746 | 11,691 | 50.0% | 100.0% | |
| 44.44% | 9 | 4.6 | 859 | 13,106 | 50.0% | 42.9% | |
| 44.44% | 9 | 6.2 | 887 | 10,783 | 66.7% | 0.0% | |
| 25.00% | 8 | 1.5 | 538 | 10,593 | 20.0% | 33.3% | |
| 28.57% | 7 | 3.1 | 738 | 10,939 | 50.0% | 0.0% | |
| 28.57% | 7 | 4.5 | 855 | 12,066 | 50.0% | 0.0% | |
| 42.86% | 7 | 2.4 | 960 | 15,101 | 50.0% | 40.0% | |
| 28.57% | 7 | 5.2 | 1,077 | 13,666 | 66.7% | 0.0% | |
| 57.14% | 7 | 4.1 | 933 | 15,594 | 50.0% | 60.0% | |
| 42.86% | 7 | 5.5 | 1,010 | 17,043 | 0.0% | 42.9% | |
| 50.00% | 6 | 5.5 | 928 | 14,680 | 0.0% | 50.0% | |
| 40.00% | 5 | 4.9 | 1,043 | 13,769 | 0.0% | 50.0% | |
| 60.00% | 5 | 0.9 | 723 | 12,175 | 50.0% | 100.0% | |
| 20.00% | 5 | 7.0 | 982 | 12,747 | 33.3% | 0.0% | |
| 40.00% | 5 | 1.2 | 735 | 13,087 | 66.7% | 0.0% | |
| 80.00% | 5 | 6.0 | 775 | 10,838 | 100.0% | 50.0% | |
| 40.00% | 5 | 3.2 | 887 | 14,902 | 33.3% | 50.0% | |
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Diana vs Karthus - Frequently Asked Questions
How does Diana do against Karthus in League of Legends?
Karthus wins the Diana vs Karthus matchup with a 76.5% win rate compared to Diana's 23.5%, a 52.9 percentage point difference. This data is based on 17 recent ranked games in patch 26.7.
How does Diana do against Karthus in the early game?
In the early game, Karthus has the advantage against Diana with a 66.7% win rate versus 33.3%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Diana do against Karthus in the late game?
In the late game, Karthus takes over the Diana vs Karthus matchup with a 87.5% win rate compared to 12.5%. Karthus scales better into team fights and objective contests after 25 minutes.
Who wins the Diana vs Karthus matchup?
Karthus wins the matchup against Diana with a 76.5% win rate in League of Legends patch 26.7. The 52.9 percentage point advantage means Karthus is significantly favored in this lane matchup based on 17 games analyzed.
What is the best Diana build against Karthus?
The best Diana build against Karthus includes Riftmaker, Zhonya's Hourglass, Dusk and Dawn with Sorcerer's Shoes. This build achieves a 33.3% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Diana runes against Karthus?
The best Diana runes against Karthus use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Diana vs Karthus matchup. See the full rune breakdown in the matchup comparison above.
Does Diana counter Karthus?
No, Diana struggles against Karthus with only a 23.5% win rate. Karthus has the advantage in this matchup. Diana players should focus on safe farming and avoiding extended trades to minimize Karthus's lead.
How do I play Diana against Karthus?
When playing Diana against Karthus, play cautiously and avoid Karthus's power spikes. Look for jungle assistance and team-dependent plays since Karthus has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.