Diana - League of Legends Champion
Win Rate
50.2%
Pick Rate
4.4%

Dianavs Karthus

BFighterAssassin
Patch26.14
Matches226,800
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Diana vs Karthus is a decisive matchup in LoL patch 26.14. Diana wins with a 60.0% win rate (+20.0%) over Karthus based on 5 games. Karthus wins the early laning phase while Diana scales better into the late game. Below you'll find the best Diana build, runes, laning stats, and strategies for the Diana vs Karthus matchup.

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Diana Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Diana performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Diana - 60.0% win rate in this matchup
Diana
60.0% WR
VS
Karthus vs Diana matchup - 40.0% win rate
Karthus
40.0% WR

Who Wins the Diana vs Karthus Matchup?

Diana wins the Diana vs Karthus matchup
Winner
Diana
Matches: 5
60.0%
Win Rate
40.0%
1.7
CS / min
0.9
907
DMG / min
1,006
14,215
Gold / game
13,487
359
Heal / min
313
1,508
DMG Mitigated / min
522
0.4
CC / min
0.6
0.0%
Early Game WR
100.0%
75.0%
Late Game WR
25.0%

Diana vs Karthus Matchup Summary

The Diana vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Diana wins with a 60.0% win rate compared to Karthus's 40.0%, giving Diana a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Karthus controls the early laning stage, but Diana outscales as the game goes longer. The matchup shifts dramatically depending on game length — Karthus needs to press advantages before Diana reaches their power spikes, while Diana should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Diana leads by 1,033 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Diana players can confidently pick into Karthus and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Karthus away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Diana vs Karthus Laning Phase Breakdown

Diana wins the laning phase against Karthus in League of Legends

Diana is favored during the laning phase against Karthus, winning 3 out of 5 key stat categories. Diana holds advantages in farming, gold income and sustain, making them the stronger laner in this matchup.

Farming
1.7Diana
0.9Karthus
Diana edges out Karthus by 0.8 CS per minute — a moderate farming advantage that adds up to roughly 11 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Diana.
Damage
907Diana
1,006Karthus
Karthus heavily out-damages Diana by 99 DMG/min, dominating both short trades and all-in fights. Diana should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
14,215Diana
13,487Karthus
Diana earns 728 more gold per game than Karthus, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Diana slightly faster item completions.
Utility
0.4Diana
0.6Karthus
Both Diana and Karthus provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
1,867Diana
834Karthus
Diana vastly out-sustains Karthus, healing and mitigating 1,033 more damage per minute. This massive durability gap means Diana can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Diana Build Against Karthus

Mercury's Treads is the optimal boots choice against Karthus, providing the mobility and stats Diana needs most in this matchup. The top-performing core items for Diana against Karthus are Riftmaker, Rabadon's Deathcap and Spirit Visage. This combination gives Diana an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Karthus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Diana vs Karthus matchup.

Early Game vs Late Game

Early Game
Karthus
100.0%
+100.0% advantage
Diana early game win rateDiana0.0%
Karthus early game win rateKarthus100.0%
Late Game
Diana
75.0%
+50.0% advantage
Diana late game win rateDiana75.0%
Karthus late game win rateKarthus25.0%

Karthus dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Diana. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Diana is far superior in the late game (25+ minutes), boasting a 75.0% win rate — 50.0 points above Karthus. Extended games heavily favor Diana, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Karthus must aggressively press their early advantage and close out the game before Diana reaches their scaling breakpoints. If Diana survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Diana Runes Against Karthus

Precision rune tree - Diana primary runes vs KarthusPrecision
Press the Attack - best Diana rune vs KarthusTriumph - best Diana rune vs KarthusLegend: Alacrity - best Diana rune vs KarthusCoup de Grace - best Diana rune vs Karthus
Domination rune tree - Diana secondary runes vs KarthusDomination
Sudden Impact - best Diana rune vs KarthusTreasure Hunter - best Diana rune vs Karthus
100.0% WR

Running Precision primary with Domination secondary allows Diana to press their advantage against Karthus, amplifying the strengths that make this a favorable matchup.


Diana matchup data for League of Legends patch 26.14. The table below shows Diana's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Diana build, runes, laning stats, and early vs late game analysis for that specific matchup.

Diana matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
54.76%844.694512,32340.6%63.5%
48.10%794.394612,56543.3%51.0%
45.61%575.686611,64866.7%33.3%
47.27%551.469712,29560.0%36.7%
50.98%515.986211,72052.2%50.0%
35.42%485.899912,21025.0%42.9%
40.43%475.494013,00846.1%38.2%
38.30%471.569811,98532.0%45.5%
65.96%475.188411,74677.3%56.0%
37.21%435.884712,00935.7%37.9%
26.83%411.373012,04911.8%37.5%
29.27%411.370913,99437.5%24.0%
58.97%391.278313,03653.3%62.5%
50.00%381.271912,49045.0%55.6%
47.37%382.679912,44156.3%40.9%
47.22%363.680712,24642.1%52.9%
47.06%345.787812,82933.3%52.0%
42.42%336.183010,92143.8%41.2%
48.48%336.394012,48553.9%45.0%
54.55%331.564311,38263.6%50.0%
44.83%291.667411,83546.1%43.8%
48.28%291.768012,63640.0%57.1%
64.29%286.182510,89664.3%64.3%
46.43%281.272512,72446.1%46.7%
46.15%265.599010,42938.5%53.9%
53.85%261.469912,43145.5%60.0%
65.38%262.086913,07276.9%53.9%
47.83%231.374412,52254.5%41.7%
65.22%236.01,07411,67554.5%75.0%
63.64%223.792212,15763.6%63.6%
71.43%216.31,04513,07571.4%71.4%
28.57%211.167112,68825.0%30.8%
65.00%201.570011,74866.7%63.6%
75.00%201.783114,68383.3%71.4%
50.00%185.886810,85050.0%50.0%
61.11%181.477212,23166.7%55.6%
55.56%186.180811,32960.0%50.0%
61.11%182.594412,70133.3%75.0%
44.44%181.388812,82920.0%53.9%
50.00%181.468012,19044.4%55.6%
50.00%181.171511,20662.5%40.0%
50.00%182.382713,62040.0%53.9%
47.06%175.990112,20733.3%54.5%
64.71%171.373711,80560.0%71.4%
50.00%161.372311,40260.0%33.3%
43.75%165.985810,94120.0%83.3%
35.71%141.169411,3930.0%55.6%
57.14%141.262310,09450.0%66.7%
42.86%146.286710,91850.0%33.3%
42.86%145.61,09912,21050.0%40.0%
46.15%135.267110,84833.3%50.0%
46.15%133.169011,87580.0%25.0%
46.15%131.783915,13033.3%50.0%
76.92%135.975910,04371.4%83.3%
58.33%125.588010,71966.7%50.0%
50.00%125.86898,97962.5%25.0%
33.33%123.86857,69220.0%100.0%
54.55%111.469613,03660.0%50.0%
72.73%111.078812,68975.0%71.4%
40.00%101.370912,11850.0%33.3%
40.00%102.994711,91640.0%40.0%
20.00%106.37679,16428.6%0.0%
60.00%101.189914,8930.0%66.7%
70.00%106.096612,922100.0%57.1%
30.00%106.094210,11025.0%33.3%
22.22%91.565610,8550.0%50.0%
55.56%91.568411,31233.3%66.7%
55.56%96.491812,864100.0%33.3%
55.56%95.71,00611,46533.3%66.7%
75.00%84.395014,49066.7%80.0%
50.00%86.089011,09450.0%50.0%
62.50%86.21,05213,73075.0%50.0%
50.00%86.796513,447100.0%33.3%
71.43%71.676515,124100.0%66.7%
57.14%74.182212,4000.0%80.0%
28.57%72.575310,78233.3%25.0%
42.86%77.79239,20950.0%0.0%
71.43%76.51,13814,616100.0%60.0%
42.86%74.091411,6740.0%60.0%
33.33%62.166414,1500.0%40.0%
33.33%66.488913,633100.0%20.0%
33.33%66.485611,06066.7%0.0%
20.00%55.694212,5090.0%33.3%
80.00%51.270910,221100.0%50.0%
40.00%54.364111,39450.0%0.0%
60.00%50.85039,98666.7%50.0%
40.00%55.784412,63050.0%33.3%
60.00%51.790714,2150.0%75.0%
80.00%50.858313,482100.0%75.0%
40.00%56.181213,4210.0%50.0%
40.00%54.45749,6950.0%50.0%

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Diana vs Karthus - Frequently Asked Questions

How does Diana do against Karthus in League of Legends?

Diana wins the Diana vs Karthus matchup with a 60.0% win rate compared to Karthus's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.14.

How does Diana do against Karthus in the early game?

In the early game, Karthus has the advantage against Diana with a 100.0% win rate versus 0.0%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Diana do against Karthus in the late game?

In the late game, Diana takes over the Diana vs Karthus matchup with a 75.0% win rate compared to 25.0%. Diana scales better into team fights and objective contests after 25 minutes.

Who wins the Diana vs Karthus matchup?

Diana wins the matchup against Karthus with a 60.0% win rate in League of Legends patch 26.14. The 20.0 percentage point advantage means Diana is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Diana build against Karthus?

The best Diana build against Karthus includes Riftmaker, Rabadon's Deathcap, Spirit Visage with Mercury's Treads. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Diana runes against Karthus?

The best Diana runes against Karthus use the Precision primary tree with Domination secondary. This rune setup achieves a 100.0% win rate in the Diana vs Karthus matchup. See the full rune breakdown in the matchup comparison above.

Does Diana counter Karthus?

Yes, Diana has a favorable matchup against Karthus with a 60.0% win rate. Diana strongly counters Karthus in lane based on current patch 26.14 data.

How do I play Diana against Karthus?

When playing Diana against Karthus, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Karthus. Build the recommended items and runes for this specific matchup for the best results.