Karthus - League of Legends Champion
Win Rate
50.2%
Pick Rate
1.2%

Karthusvs Dr. Mundo

BMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 2, 2026
MethodologyData Methodology

Karthus vs Dr. Mundo is a decisive matchup in LoL patch 26.11. Dr. Mundo wins with a 66.7% win rate (+33.3%) over Karthus based on 9 games. Dr. Mundo holds the advantage in both the early and late game. Below you'll find the best Karthus build, runes, laning stats, and strategies for the Karthus vs Dr. Mundo matchup.

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Karthus Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Karthus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karthus - 33.3% win rate in this matchup
Karthus
33.3% WR
VS
Dr. Mundo vs Karthus matchup - 66.7% win rate
Dr. Mundo
66.7% WR

Who Wins the Karthus vs Dr. Mundo Matchup?

Dr. Mundo wins the Karthus vs Dr. Mundo matchup
Winner
Dr. Mundo
Matches: 9
33.3%
Win Rate
66.7%
2.1
CS / min
1.8
1,195
DMG / min
794
13,834
Gold / game
14,233
287
Heal / min
1,090
495
DMG Mitigated / min
1,660
0.6
CC / min
0.6
33.3%
Early Game WR
66.7%
33.3%
Late Game WR
66.7%

Karthus vs Dr. Mundo Matchup Summary

The Karthus vs Dr. Mundo matchup is a decisive matchup in League of Legends ranked play. Based on 9 recent matches analyzed, Dr. Mundo wins with a 66.7% win rate compared to Karthus's 33.3%, giving Dr. Mundo a 33.3 percentage point advantage. Dr. Mundo dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Karthus players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Dr. Mundo leads by 1,968 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Dr. Mundo has a strong advantage in this matchup. Karthus players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Dr. Mundo overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Karthus vs Dr. Mundo Laning Phase Breakdown

Karthus wins the laning phase against Dr. Mundo in League of Legends

Karthus is favored during the laning phase against Dr. Mundo, winning 3 out of 5 key stat categories. Karthus holds advantages in farming, damage and crowd control, making them the stronger laner in this matchup.

Farming
2.1Karthus
1.8Dr. Mundo
Karthus and Dr. Mundo farm at nearly identical rates in this matchup, with only a 0.3 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
1,195Karthus
794Dr. Mundo
Karthus heavily out-damages Dr. Mundo by 401 DMG/min, dominating both short trades and all-in fights. Dr. Mundo should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
13,834Karthus
14,233Dr. Mundo
Dr. Mundo earns 399 more gold per game than Karthus, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Dr. Mundo slightly faster item completions.
Utility
0.6Karthus
0.6Dr. Mundo
Both Karthus and Dr. Mundo provide similar amounts of crowd control (0.0s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
782Karthus
2,750Dr. Mundo
Dr. Mundo vastly out-sustains Karthus, healing and mitigating 1,968 more damage per minute. This massive durability gap means Dr. Mundo can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Karthus Build Against Dr. Mundo

Sorcerer's Shoes is the optimal boots choice against Dr. Mundo, providing the mobility and stats Karthus needs most in this matchup. The top-performing core items for Karthus against Dr. Mundo are Shadowflame, Zhonya's Hourglass and Rabadon's Deathcap. This combination gives Karthus an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Dr. Mundo. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karthus vs Dr. Mundo matchup.

Early Game vs Late Game

Early Game
Dr. Mundo
66.7%
+33.3% advantage
Karthus early game win rateKarthus33.3%
Dr. Mundo early game win rateDr. Mundo66.7%
Late Game
Dr. Mundo
66.7%
+33.3% advantage
Karthus late game win rateKarthus33.3%
Dr. Mundo late game win rateDr. Mundo66.7%

Dr. Mundo dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Karthus. This lopsided early game means Dr. Mundo can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Dr. Mundo is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Karthus. Extended games heavily favor Dr. Mundo, whose kit and scaling make them a dominant force in team fights and objective control.

Dr. Mundo holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Karthus players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Karthus Runes Against Dr. Mundo

Sorcery rune tree - Karthus primary runes vs Dr. MundoSorcery
Deathfire Touch - best Karthus rune vs Dr. MundoAxiom Arcanist - best Karthus rune vs Dr. MundoAbsolute Focus - best Karthus rune vs Dr. MundoGathering Storm - best Karthus rune vs Dr. Mundo
Precision rune tree - Karthus secondary runes vs Dr. MundoPrecision
Coup de Grace - best Karthus rune vs Dr. MundoTriumph - best Karthus rune vs Dr. Mundo
100.0% WR

The Sorcery and Precision rune setup gives Karthus the best tools to compete against Dr. Mundo in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Karthus matchup data for League of Legends patch 26.11. The table below shows Karthus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karthus build, runes, laning stats, and early vs late game analysis for that specific matchup.

Karthus matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.09%551.41,03012,95747.8%50.0%
43.64%551.71,17013,03740.0%46.7%
45.10%511.61,05713,34631.8%55.2%
59.18%496.31,29113,60950.0%65.5%
52.08%481.51,25914,65547.1%54.8%
42.22%451.51,01713,07143.8%41.4%
37.78%451.31,02712,76840.9%34.8%
64.44%456.51,32616,02286.7%53.3%
50.00%426.61,19713,07066.7%33.3%
43.59%396.31,21513,23850.0%36.8%
57.89%381.41,26313,76053.3%60.9%
47.37%381.51,14413,40237.5%54.5%
34.21%381.91,06712,86740.0%30.4%
43.24%371.81,21213,46357.1%34.8%
38.24%347.01,24713,84233.3%42.1%
46.88%321.81,14612,84538.5%52.6%
43.33%301.81,29414,56958.3%33.3%
55.17%296.11,20312,39066.7%42.9%
46.43%281.41,03012,47453.3%38.5%
57.14%286.61,42315,21450.0%62.5%
40.74%271.31,33515,99216.7%47.6%
28.00%251.81,16313,29530.0%26.7%
66.67%241.61,14614,33775.0%58.3%
45.45%221.51,30714,90550.0%44.4%
66.67%212.21,20113,57277.8%58.3%
55.00%201.61,26713,96860.0%50.0%
68.42%195.61,49616,092100.0%60.0%
63.16%191.31,11614,40962.5%63.6%
38.89%181.51,44814,53542.9%36.4%
55.56%186.41,27613,45466.7%44.4%
72.22%185.11,12111,32260.0%87.5%
35.29%171.51,05612,45536.4%33.3%
52.94%171.31,37015,16157.1%50.0%
76.47%176.51,26315,48280.0%75.0%
47.06%171.596012,24444.4%50.0%
52.94%176.51,33013,71966.7%45.5%
43.75%161.41,24415,49750.0%41.7%
56.25%161.31,08013,22180.0%45.5%
53.33%155.41,37313,67875.0%45.5%
35.71%141.61,23913,56744.4%20.0%
28.57%146.71,35911,93450.0%12.5%
42.86%142.41,25014,77740.0%44.4%
50.00%141.61,08215,54125.0%60.0%
69.23%136.51,30513,96557.1%83.3%
61.54%136.51,25612,93960.0%62.5%
53.85%132.51,05212,27675.0%44.4%
58.33%125.91,02710,26957.1%60.0%
83.33%121.31,22913,18380.0%85.7%
50.00%125.41,34014,96775.0%37.5%
45.45%111.41,03113,14557.1%25.0%
72.73%111.61,02712,997100.0%57.1%
27.27%115.91,13213,2320.0%42.9%
30.00%103.21,05913,47225.0%33.3%
70.00%107.41,27115,568100.0%57.1%
70.00%102.91,14415,271100.0%62.5%
50.00%107.21,13812,21650.0%50.0%
40.00%102.91,37615,5780.0%44.4%
55.56%95.51,26613,15150.0%60.0%
33.33%94.992710,92520.0%50.0%
44.44%96.21,07210,46733.3%66.7%
55.56%93.31,21214,875100.0%42.9%
55.56%91.41,25215,076100.0%42.9%
77.78%92.91,16514,15366.7%83.3%
33.33%92.11,19513,83433.3%33.3%
87.50%81.31,11314,33780.0%100.0%
25.00%81.31,28513,22250.0%16.7%
87.50%86.41,18214,46450.0%100.0%
75.00%81.71,65016,96550.0%83.3%
75.00%86.71,19715,02375.0%75.0%
62.50%82.099113,519100.0%50.0%
37.50%81.799613,5240.0%50.0%
57.14%76.31,63217,174100.0%50.0%
42.86%72.91,10811,95025.0%66.7%
14.29%71.190712,62625.0%0.0%
71.43%76.91,20214,28450.0%80.0%
85.71%75.51,33217,1080.0%85.7%
42.86%74.11,21013,9640.0%50.0%
28.57%76.01,44213,3670.0%40.0%
57.14%77.01,42713,69033.3%75.0%
57.14%72.41,12412,10740.0%100.0%
85.71%71.01,06214,10450.0%100.0%
50.00%67.11,38812,74350.0%50.0%
33.33%66.81,14411,4860.0%66.7%
66.67%64.21,44015,135100.0%60.0%
33.33%62.39659,7790.0%50.0%
33.33%62.51,07412,12050.0%0.0%
33.33%66.61,31611,4480.0%66.7%
16.67%65.81,30313,2700.0%25.0%
50.00%62.51,43716,7350.0%75.0%
20.00%56.31,40913,9390.0%33.3%
40.00%55.37986,5180.0%100.0%
40.00%51.11,41814,8040.0%50.0%
40.00%53.41,19015,0350.0%50.0%
60.00%54.61,65613,73266.7%50.0%
80.00%56.71,33110,47066.7%100.0%
60.00%52.01,29214,405100.0%50.0%
20.00%56.01,20610,84633.3%0.0%
40.00%56.71,01212,7100.0%50.0%
40.00%56.31,48213,690100.0%25.0%
60.00%55.91,40013,38366.7%50.0%
40.00%56.51,1899,67725.0%100.0%

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Karthus vs Dr. Mundo - Frequently Asked Questions

How does Karthus do against Dr. Mundo in League of Legends?

Dr. Mundo wins the Karthus vs Dr. Mundo matchup with a 66.7% win rate compared to Karthus's 33.3%, a 33.3 percentage point difference. This data is based on 9 recent ranked games in patch 26.11.

How does Karthus do against Dr. Mundo in the early game?

In the early game, Dr. Mundo has the advantage against Karthus with a 66.7% win rate versus 33.3%. Dr. Mundo players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Karthus do against Dr. Mundo in the late game?

In the late game, Dr. Mundo takes over the Karthus vs Dr. Mundo matchup with a 66.7% win rate compared to 33.3%. Dr. Mundo scales better into team fights and objective contests after 25 minutes.

Who wins the Karthus vs Dr. Mundo matchup?

Dr. Mundo wins the matchup against Karthus with a 66.7% win rate in League of Legends patch 26.11. The 33.3 percentage point advantage means Dr. Mundo is significantly favored in this lane matchup based on 9 games analyzed.

What is the best Karthus build against Dr. Mundo?

The best Karthus build against Dr. Mundo includes Shadowflame, Zhonya's Hourglass, Rabadon's Deathcap with Sorcerer's Shoes. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Karthus runes against Dr. Mundo?

The best Karthus runes against Dr. Mundo use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Karthus vs Dr. Mundo matchup. See the full rune breakdown in the matchup comparison above.

Does Karthus counter Dr. Mundo?

No, Karthus struggles against Dr. Mundo with only a 33.3% win rate. Dr. Mundo has the advantage in this matchup. Karthus players should focus on safe farming and avoiding extended trades to minimize Dr. Mundo's lead.

How do I play Karthus against Dr. Mundo?

When playing Karthus against Dr. Mundo, play cautiously and avoid Dr. Mundo's power spikes. Look for jungle assistance and team-dependent plays since Dr. Mundo has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.