Lissandra - League of Legends Champion
Win Rate
51.6%
Pick Rate
1.7%

Lissandravs Pantheon

SMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 7, 2026
MethodologyData Methodology

Lissandra vs Pantheon is a decisive matchup in LoL patch 26.11. Pantheon wins with a 54.5% win rate (+9.1%) over Lissandra based on 11 games. Pantheon wins the early laning phase while Lissandra scales better into the late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Pantheon matchup.

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Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lissandra - 45.5% win rate in this matchup
Lissandra
45.5% WR
VS
Pantheon vs Lissandra matchup - 54.5% win rate
Pantheon
54.5% WR

Who Wins the Lissandra vs Pantheon Matchup?

Pantheon wins the Lissandra vs Pantheon matchup
Winner
Pantheon
Matches: 11
45.5%
Win Rate
54.5%
5.5
CS / min
4.3
904
DMG / min
906
12,094
Gold / game
12,422
139
Heal / min
180
529
DMG Mitigated / min
799
1.9
CC / min
0.8
25.0%
Early Game WR
75.0%
57.1%
Late Game WR
42.9%

Lissandra vs Pantheon Matchup Summary

The Lissandra vs Pantheon matchup is a decisive matchup in League of Legends ranked play. Based on 11 recent matches analyzed, Pantheon wins with a 54.5% win rate compared to Lissandra's 45.5%, giving Pantheon a 9.1 percentage point advantage. Game phase dynamics play a critical role here: Pantheon controls the early laning stage, but Lissandra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Pantheon needs to press advantages before Lissandra reaches their power spikes, while Lissandra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Lissandra leads by 1.1s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Pantheon has a strong advantage in this matchup. Lissandra players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Pantheon overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Pantheon Laning Phase Breakdown

Pantheon wins the laning phase against Lissandra in League of Legends

Pantheon is favored during the laning phase against Lissandra, winning 3 out of 5 key stat categories. Pantheon holds advantages in damage, gold income and sustain, making them the stronger laner in this matchup.

Farming
5.5Lissandra
4.3Pantheon
Lissandra significantly out-farms Pantheon by 1.2 CS per minute, accumulating an estimated 18 CS lead by mid game. This substantial farming gap gives Lissandra a major gold advantage and earlier item completions. Pantheon players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
904Lissandra
906Pantheon
Damage output is virtually even between Lissandra and Pantheon, with only 1 DMG/min separating them. Fights in this matchup are decided more by ability timing and positioning than raw damage numbers, making mechanical skill the deciding factor in trades.
Economy
12,094Lissandra
12,422Pantheon
Pantheon earns 328 more gold per game than Lissandra, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Pantheon slightly faster item completions.
Utility
1.9Lissandra
0.8Pantheon
Lissandra brings significantly more crowd control than Pantheon, with 1.1 more seconds of CC per minute. This large utility gap makes Lissandra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Pantheon should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
668Lissandra
979Pantheon
Pantheon vastly out-sustains Lissandra, healing and mitigating 311 more damage per minute. This massive durability gap means Pantheon can absorb significant punishment and remain in lane while Lissandra is forced to recall. Building grievous wounds early is essential for Lissandra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Lissandra Build Against Pantheon

Sorcerer's Shoes is the optimal boots choice against Pantheon, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Pantheon are Shadowflame, Zhonya's Hourglass and Void Staff. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 2 games — well above average and making it the top item path against Pantheon. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Pantheon matchup.

Early Game vs Late Game

Early Game
Pantheon
75.0%
+50.0% advantage
Lissandra early game win rateLissandra25.0%
Pantheon early game win ratePantheon75.0%
Late Game
Lissandra
57.1%
+14.3% advantage
Lissandra late game win rateLissandra57.1%
Pantheon late game win ratePantheon42.9%

Pantheon dominates the early game (first 15 minutes) with a commanding 75.0% win rate — a 50.0 percentage point lead over Lissandra. This lopsided early game means Pantheon can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Lissandra is far superior in the late game (25+ minutes), boasting a 57.1% win rate — 14.3 points above Pantheon. Extended games heavily favor Lissandra, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Pantheon must aggressively press their early advantage and close out the game before Lissandra reaches their scaling breakpoints. If Lissandra survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Lissandra Runes Against Pantheon

Domination rune tree - Lissandra primary runes vs PantheonDomination
Electrocute - best Lissandra rune vs PantheonCheap Shot - best Lissandra rune vs PantheonGrisly Mementos - best Lissandra rune vs PantheonUltimate Hunter - best Lissandra rune vs Pantheon
Sorcery rune tree - Lissandra secondary runes vs PantheonSorcery
Axiom Arcanist - best Lissandra rune vs PantheonTranscendence - best Lissandra rune vs Pantheon
100.0% WR

The Domination and Sorcery rune setup gives Lissandra the best tools to compete against Pantheon in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Lissandra matchup data for League of Legends patch 26.11. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
58.02%1316.885811,86355.0%60.6%
61.60%1256.791812,36268.6%56.8%
54.47%1236.988112,08353.1%55.4%
54.95%1116.874811,41055.8%54.2%
51.52%996.684011,78453.5%50.0%
50.00%986.985712,17845.0%53.5%
55.56%816.992811,72160.5%51.2%
44.74%766.878111,74844.1%45.2%
57.53%736.785911,06161.5%52.9%
52.86%706.487411,10854.3%51.4%
48.53%687.090811,10755.0%39.3%
53.73%676.178010,94653.1%54.3%
48.28%586.778112,35453.9%43.8%
41.07%566.774210,62436.7%46.1%
58.93%566.573210,32060.6%56.5%
53.70%546.488811,71551.9%55.6%
52.08%486.888112,08468.2%38.5%
55.32%476.384311,46055.6%55.2%
51.16%436.883412,58750.0%51.9%
43.59%396.482510,76435.0%52.6%
46.15%396.577310,88341.2%50.0%
39.47%386.680212,13937.5%40.9%
56.76%376.374210,61842.1%72.2%
56.76%376.878712,41658.8%55.0%
56.76%376.880811,53576.9%45.8%
32.43%377.080410,61129.4%35.0%
48.65%377.083812,68066.7%40.0%
33.33%336.992311,15131.3%35.3%
66.67%306.784412,08075.0%61.1%
65.52%296.986511,46770.6%58.3%
53.57%286.785811,89133.3%63.2%
61.54%267.193811,18175.0%40.0%
37.50%246.470111,94744.4%33.3%
58.33%247.382212,59060.0%57.1%
50.00%227.076411,84454.5%45.5%
54.55%226.61,01413,02066.7%50.0%
31.82%226.768410,84522.2%38.5%
33.33%216.874611,90044.4%25.0%
57.14%215.782310,46554.5%60.0%
73.68%196.980510,70775.0%72.7%
57.89%196.985412,58375.0%45.5%
61.11%187.488713,06550.0%70.0%
38.89%187.294812,87866.7%25.0%
58.82%176.51,06612,41342.9%70.0%
62.50%166.268611,07572.7%40.0%
56.25%166.892312,01450.0%57.1%
66.67%156.984213,080100.0%54.5%
64.29%146.190813,43275.0%60.0%
50.00%144.254910,94350.0%50.0%
64.29%146.779211,67883.3%50.0%
57.14%147.01,08911,13070.0%25.0%
53.85%136.693411,37550.0%57.1%
58.33%127.51,05412,44966.7%50.0%
63.64%116.090612,08133.3%100.0%
45.45%115.590412,09425.0%57.1%
63.64%112.682511,48750.0%71.4%
30.00%105.47418,70242.9%0.0%
70.00%107.194411,75183.3%50.0%
70.00%106.21,13613,233100.0%50.0%
50.00%106.889914,6330.0%62.5%
70.00%106.481112,0790.0%87.5%
55.56%96.281411,09650.0%66.7%
33.33%96.885511,75450.0%20.0%
66.67%96.578212,16033.3%83.3%
22.22%92.55189,7830.0%40.0%
85.71%77.71,15311,498100.0%66.7%
71.43%76.482813,449100.0%66.7%
57.14%77.384211,22350.0%66.7%
100.00%78.28329,161100.0%100.0%
57.14%72.986810,35560.0%50.0%
42.86%77.48559,99550.0%33.3%
57.14%77.080513,44150.0%66.7%
50.00%66.469210,47333.3%66.7%
33.33%66.78659,25050.0%0.0%
50.00%65.784212,7490.0%50.0%
80.00%56.88199,894100.0%66.7%
60.00%57.671711,88250.0%66.7%
60.00%57.593814,8270.0%75.0%
40.00%52.155411,1230.0%40.0%
60.00%56.576611,909100.0%50.0%
40.00%56.95498,21433.3%50.0%
80.00%53.669512,683100.0%50.0%
60.00%52.24318,35366.7%50.0%
60.00%57.51,17014,036100.0%33.3%
40.00%55.596514,4230.0%40.0%
80.00%57.31,24116,644100.0%75.0%
80.00%56.388712,12650.0%100.0%
60.00%56.074710,44750.0%100.0%
20.00%56.67479,3500.0%33.3%

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Lissandra vs Pantheon - Frequently Asked Questions

How does Lissandra do against Pantheon in League of Legends?

Pantheon wins the Lissandra vs Pantheon matchup with a 54.5% win rate compared to Lissandra's 45.5%, a 9.1 percentage point difference. This data is based on 11 recent ranked games in patch 26.11.

How does Lissandra do against Pantheon in the early game?

In the early game, Pantheon has the advantage against Lissandra with a 75.0% win rate versus 25.0%. Pantheon players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Pantheon in the late game?

In the late game, Lissandra takes over the Lissandra vs Pantheon matchup with a 57.1% win rate compared to 42.9%. Lissandra scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Pantheon matchup?

Pantheon wins the matchup against Lissandra with a 54.5% win rate in League of Legends patch 26.11. The 9.1 percentage point advantage means Pantheon is significantly favored in this lane matchup based on 11 games analyzed.

What is the best Lissandra build against Pantheon?

The best Lissandra build against Pantheon includes Shadowflame, Zhonya's Hourglass, Void Staff with Sorcerer's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Pantheon?

The best Lissandra runes against Pantheon use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Lissandra vs Pantheon matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Pantheon?

No, Lissandra struggles against Pantheon with only a 45.5% win rate. Pantheon has the advantage in this matchup. Lissandra players should focus on safe farming and avoiding extended trades to minimize Pantheon's lead.

How do I play Lissandra against Pantheon?

When playing Lissandra against Pantheon, play cautiously and avoid Pantheon's power spikes. Focus on safe farming — you outscale Pantheon in the late game. Use the matchup-specific build and runes above to optimize your chances.