Pantheon - League of Legends Champion
Win Rate
49.5%
Pick Rate
3.8%

Pantheonvs Lissandra

DFighterAssassin
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 19, 2026
MethodologyData Methodology

Pantheon vs Lissandra is a decisive matchup in LoL patch 26.7. Pantheon wins with a 60.0% win rate (+20.0%) over Lissandra based on 10 games. Lissandra wins the early laning phase while Pantheon scales better into the late game. Below you'll find the best Pantheon build, runes, laning stats, and strategies for the Pantheon vs Lissandra matchup.

Pantheon Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Pantheon performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lissandra - 60.0% win rateLissandra(60.0%)
Pantheon - 60.0% win rate in this matchup
Pantheon
60.0% WR
VS
Lissandra vs Pantheon matchup - 40.0% win rate
Lissandra
40.0% WR

Who Wins the Pantheon vs Lissandra Matchup?

Pantheon wins the Pantheon vs Lissandra matchup
Winner
Pantheon
Matches: 10
60.0%
Win Rate
40.0%
5.0
CS / min
6.8
799
DMG / min
825
11,788
Gold / game
12,831
188
Heal / min
170
879
DMG Mitigated / min
513
0.9
CC / min
1.8
33.3%
Early Game WR
66.7%
71.4%
Late Game WR
28.6%

Pantheon vs Lissandra Matchup Summary

The Pantheon vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 10 recent matches analyzed, Pantheon wins with a 60.0% win rate compared to Lissandra's 40.0%, giving Pantheon a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Lissandra controls the early laning stage, but Pantheon outscales as the game goes longer. The matchup shifts dramatically depending on game length — Lissandra needs to press advantages before Pantheon reaches their power spikes, while Pantheon should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Lissandra leads by 0.9s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Pantheon players can confidently pick into Lissandra and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Lissandra away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Pantheon vs Lissandra Laning Phase Breakdown

Lissandra wins the laning phase against Pantheon in League of Legends

Lissandra is favored during the laning phase against Pantheon, winning 4 out of 5 key stat categories. Lissandra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
5.0Pantheon
6.8Lissandra
Lissandra significantly out-farms Pantheon by 1.8 CS per minute, accumulating an estimated 26 CS lead by mid game. This substantial farming gap gives Lissandra a major gold advantage and earlier item completions. Pantheon players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
799Pantheon
825Lissandra
Damage output is virtually even between Pantheon and Lissandra, with only 26 DMG/min separating them. Fights in this matchup are decided more by ability timing and positioning than raw damage numbers, making mechanical skill the deciding factor in trades.
Economy
11,788Pantheon
12,831Lissandra
Lissandra generates a commanding 1,044 more gold per game than Pantheon. This substantial economic advantage means Lissandra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Pantheon should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.9Pantheon
1.8Lissandra
Lissandra brings significantly more crowd control than Pantheon, with 0.9 more seconds of CC per minute. This large utility gap makes Lissandra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Pantheon should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
1,067Pantheon
683Lissandra
Pantheon vastly out-sustains Lissandra, healing and mitigating 384 more damage per minute. This massive durability gap means Pantheon can absorb significant punishment and remain in lane while Lissandra is forced to recall. Building grievous wounds early is essential for Lissandra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Pantheon Build Against Lissandra

Chainlaced Crushers is the optimal boots choice against Lissandra, providing the mobility and stats Pantheon needs most in this matchup. The top-performing core items for Pantheon against Lissandra are Eclipse, Sundered Sky and Black Cleaver. This combination gives Pantheon an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Lissandra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Pantheon vs Lissandra matchup.

Early Game vs Late Game

Early Game
Lissandra
66.7%
+33.3% advantage
Pantheon early game win ratePantheon33.3%
Lissandra early game win rateLissandra66.7%
Late Game
Pantheon
71.4%
+42.9% advantage
Pantheon late game win ratePantheon71.4%
Lissandra late game win rateLissandra28.6%

Lissandra dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Pantheon. This lopsided early game means Lissandra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Pantheon is far superior in the late game (25+ minutes), boasting a 71.4% win rate — 42.9 points above Lissandra. Extended games heavily favor Pantheon, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Lissandra must aggressively press their early advantage and close out the game before Pantheon reaches their scaling breakpoints. If Pantheon survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Pantheon Runes Against Lissandra

Domination rune tree - Pantheon primary runes vs LissandraDomination
Electrocute - best Pantheon rune vs LissandraSudden Impact - best Pantheon rune vs LissandraSixth Sense - best Pantheon rune vs LissandraTreasure Hunter - best Pantheon rune vs Lissandra
Precision rune tree - Pantheon secondary runes vs LissandraPrecision
Triumph - best Pantheon rune vs LissandraLegend: Haste - best Pantheon rune vs Lissandra
100.0% WR

Running Domination primary with Precision secondary allows Pantheon to press their advantage against Lissandra, amplifying the strengths that make this a favorable matchup.


Pantheon matchup data for League of Legends patch 26.7. The table below shows Pantheon's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Pantheon build, runes, laning stats, and early vs late game analysis for that specific matchup.

Pantheon matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
58.41%1135.792412,05259.6%57.4%
55.45%1012.266610,63658.7%52.7%
53.26%921.56479,84044.9%62.8%
46.67%751.565210,93146.4%46.8%
41.67%721.66499,78033.3%47.6%
50.00%701.771010,58150.0%50.0%
42.42%665.690212,13554.8%31.4%
43.94%661.567111,03844.0%43.9%
49.21%635.485711,60648.0%50.0%
49.12%571.670410,80747.8%50.0%
47.37%571.570310,35343.5%50.0%
50.00%562.077811,16956.5%45.5%
44.44%541.67049,86544.4%44.4%
34.62%532.683710,60131.8%36.7%
46.15%525.11,01011,32153.9%38.5%
55.77%521.969811,14947.8%62.1%
54.90%514.575310,22557.1%52.2%
52.00%501.475410,29950.0%53.9%
44.90%493.599312,72550.0%41.4%
54.17%481.669810,33044.8%68.4%
51.06%471.463810,34740.0%59.3%
44.68%471.566710,84041.2%46.7%
44.68%473.183412,34025.0%54.8%
62.22%455.790812,11276.2%50.0%
53.33%455.283210,86654.5%52.2%
43.18%443.982311,88459.1%27.3%
60.00%404.888112,23961.1%59.1%
38.46%394.882010,68341.7%33.3%
46.15%391.464310,29858.8%36.4%
48.65%376.088310,81755.0%41.2%
48.65%371.46269,62257.9%38.9%
64.86%371.467610,13060.0%70.6%
61.11%361.571911,89541.7%70.8%
55.56%361.665210,26263.2%47.1%
44.44%361.670711,96345.5%44.0%
44.12%341.779512,15344.4%43.8%
55.88%345.890211,58850.0%62.5%
58.82%344.372411,54260.0%57.9%
48.48%334.397012,37546.1%50.0%
36.36%331.370612,11737.5%35.3%
48.48%331.273010,88063.6%40.9%
50.00%322.661910,71150.0%50.0%
50.00%321.470512,15242.9%55.6%
41.94%314.183111,03947.1%35.7%
41.94%311.163011,81343.8%40.0%
43.33%300.871911,88550.0%37.5%
60.00%304.282610,99247.6%88.9%
58.62%296.081711,36656.3%61.5%
37.93%293.690412,39630.8%43.8%
64.29%281.465611,34258.8%72.7%
28.57%281.364510,29723.1%33.3%
53.57%283.595912,66746.7%61.5%
35.71%282.879511,27236.4%35.3%
67.86%283.385212,31191.7%50.0%
71.43%285.493410,33258.8%90.9%
40.74%272.467410,07450.0%30.8%
44.44%271.378813,06550.0%42.1%
59.26%275.897813,28463.6%56.3%
34.62%265.280211,23127.3%40.0%
61.54%264.794212,05250.0%68.8%
36.00%255.580611,62935.7%36.4%
40.00%254.786012,90222.2%50.0%
44.00%255.494712,17033.3%50.0%
48.00%251.575410,78446.7%50.0%
50.00%243.688412,43360.0%42.9%
62.50%245.21,05411,77369.2%54.5%
78.26%235.387412,15066.7%85.7%
65.22%231.672910,82442.9%75.0%
52.17%233.276411,68758.3%45.5%
47.83%235.61,00812,81571.4%37.5%
43.48%234.681710,08653.9%30.0%
50.00%222.876612,87833.3%56.3%
68.18%221.373712,61257.1%73.3%
31.82%220.957610,80528.6%37.5%
68.18%225.893011,31375.0%64.3%
36.36%225.592310,31038.5%33.3%
52.38%215.386311,60366.7%46.7%
61.90%210.976913,778100.0%50.0%
50.00%204.679210,43560.0%40.0%
45.00%200.965111,60940.0%50.0%
65.00%201.669011,34970.0%60.0%
60.00%204.486912,85550.0%64.3%
45.00%204.589211,05011.1%72.7%
31.58%191.77069,04733.3%28.6%
15.79%191.567212,0110.0%21.4%
61.11%180.884112,79655.6%66.7%
44.44%183.285211,57566.7%33.3%
52.94%171.474610,74950.0%55.6%
47.06%172.174312,92850.0%45.5%
52.94%175.889610,11455.6%50.0%
41.18%170.878412,29442.9%40.0%
56.25%165.487612,95180.0%45.5%
37.50%165.675111,85937.5%37.5%
37.50%162.692111,55325.0%50.0%
43.75%165.893011,76237.5%50.0%
56.25%160.875213,67150.0%58.3%
31.25%165.496113,86360.0%18.2%
53.33%154.37499,87355.6%50.0%
53.33%153.585512,53525.0%63.6%
60.00%155.485013,56975.0%54.5%
78.57%145.699812,48260.0%88.9%
50.00%145.577810,38883.3%25.0%
64.29%141.46179,82762.5%66.7%
35.71%143.371210,50250.0%16.7%
57.14%145.21,09512,66960.0%55.6%
35.71%141.469612,14866.7%12.5%
21.43%144.459010,07320.0%22.2%
28.57%144.689713,67016.7%37.5%
38.46%131.069112,32833.3%42.9%
53.85%130.979313,16350.0%57.1%
38.46%132.26069,51333.3%50.0%
30.77%134.985912,26940.0%25.0%
53.85%134.374810,89462.5%40.0%
16.67%124.880411,72825.0%12.5%
72.73%114.379311,72562.5%100.0%
27.27%113.179212,11150.0%14.3%
54.55%110.859911,12475.0%42.9%
50.00%103.782513,04366.7%42.9%
20.00%101.86309,68616.7%25.0%
50.00%104.795512,05920.0%80.0%
60.00%105.079911,78833.3%71.4%
50.00%105.91,11013,42325.0%66.7%
40.00%106.094512,69450.0%33.3%
60.00%105.08028,26260.0%60.0%
55.56%95.079612,02866.7%50.0%
55.56%95.190910,91157.1%50.0%
44.44%95.490811,48133.3%50.0%
44.44%95.573611,74333.3%66.7%
62.50%85.291713,9590.0%71.4%
62.50%80.968612,33360.0%66.7%
50.00%85.71,06510,83950.0%50.0%
50.00%81.274513,6060.0%66.7%
62.50%82.882811,415100.0%50.0%
57.14%74.47229,13340.0%100.0%
57.14%71.388411,11425.0%100.0%
57.14%73.272611,82250.0%66.7%
85.71%72.275812,01775.0%100.0%
42.86%72.895114,45850.0%40.0%
42.86%74.391714,1130.0%50.0%
57.14%70.774613,01950.0%60.0%
42.86%71.777912,46450.0%40.0%
33.33%63.789912,43350.0%0.0%
50.00%64.477412,32650.0%50.0%
50.00%64.868312,816100.0%25.0%
50.00%60.879312,58966.7%33.3%
33.33%65.066711,57250.0%25.0%
33.33%60.975011,6580.0%50.0%
83.33%60.679613,3340.0%100.0%
100.00%52.490212,862100.0%100.0%
40.00%51.964013,3560.0%50.0%
40.00%54.171012,55766.7%0.0%
80.00%54.47578,94366.7%100.0%

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Pantheon vs Lissandra - Frequently Asked Questions

How does Pantheon do against Lissandra in League of Legends?

Pantheon wins the Pantheon vs Lissandra matchup with a 60.0% win rate compared to Lissandra's 40.0%, a 20.0 percentage point difference. This data is based on 10 recent ranked games in patch 26.7.

How does Pantheon do against Lissandra in the early game?

In the early game, Lissandra has the advantage against Pantheon with a 66.7% win rate versus 33.3%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Pantheon do against Lissandra in the late game?

In the late game, Pantheon takes over the Pantheon vs Lissandra matchup with a 71.4% win rate compared to 28.6%. Pantheon scales better into team fights and objective contests after 25 minutes.

Who wins the Pantheon vs Lissandra matchup?

Pantheon wins the matchup against Lissandra with a 60.0% win rate in League of Legends patch 26.7. The 20.0 percentage point advantage means Pantheon is significantly favored in this lane matchup based on 10 games analyzed.

What is the best Pantheon build against Lissandra?

The best Pantheon build against Lissandra includes Eclipse, Sundered Sky, Black Cleaver with Chainlaced Crushers. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Pantheon runes against Lissandra?

The best Pantheon runes against Lissandra use the Domination primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Pantheon vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.

Does Pantheon counter Lissandra?

Yes, Pantheon has a favorable matchup against Lissandra with a 60.0% win rate. Pantheon strongly counters Lissandra in lane based on current patch 26.7 data.

How do I play Pantheon against Lissandra?

When playing Pantheon against Lissandra, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Lissandra. Build the recommended items and runes for this specific matchup for the best results.