Pantheon - League of Legends Champion
Win Rate
49.5%
Pick Rate
4.4%

Pantheonvs Lissandra

DFighterAssassin
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Pantheon vs Lissandra is a decisive matchup in LoL patch 26.14. Pantheon wins with a 57.1% win rate (+14.3%) over Lissandra based on 7 games. Pantheon wins the early laning phase while Lissandra scales better into the late game. Below you'll find the best Pantheon build, runes, laning stats, and strategies for the Pantheon vs Lissandra matchup.

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Pantheon Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Pantheon performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Pantheon - 57.1% win rate in this matchup
Pantheon
57.1% WR
VS
Lissandra vs Pantheon matchup - 42.9% win rate
Lissandra
42.9% WR

Who Wins the Pantheon vs Lissandra Matchup?

Pantheon wins the Pantheon vs Lissandra matchup
Winner
Pantheon
Matches: 7
57.1%
Win Rate
42.9%
3.3
CS / min
4.6
694
DMG / min
731
10,427
Gold / game
11,076
139
Heal / min
121
682
DMG Mitigated / min
435
0.9
CC / min
1.9
75.0%
Early Game WR
25.0%
33.3%
Late Game WR
66.7%

Pantheon vs Lissandra Matchup Summary

The Pantheon vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Pantheon wins with a 57.1% win rate compared to Lissandra's 42.9%, giving Pantheon a 14.3 percentage point advantage. Game phase dynamics play a critical role here: Pantheon controls the early laning stage, but Lissandra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Pantheon needs to press advantages before Lissandra reaches their power spikes, while Lissandra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Lissandra leads by 1.1s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Pantheon players can confidently pick into Lissandra and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Lissandra away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Pantheon vs Lissandra Laning Phase Breakdown

Lissandra wins the laning phase against Pantheon in League of Legends

Lissandra is favored during the laning phase against Pantheon, winning 4 out of 5 key stat categories. Lissandra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
3.3Pantheon
4.6Lissandra
Lissandra significantly out-farms Pantheon by 1.3 CS per minute, accumulating an estimated 19 CS lead by mid game. This substantial farming gap gives Lissandra a major gold advantage and earlier item completions. Pantheon players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
694Pantheon
731Lissandra
Lissandra deals 37 more champion damage per minute than Pantheon. While noticeable in extended trades, this gap can be offset by Pantheon choosing favorable fight windows, such as engaging when Lissandra's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
10,427Pantheon
11,076Lissandra
Lissandra earns 649 more gold per game than Pantheon, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Lissandra slightly faster item completions.
Utility
0.9Pantheon
1.9Lissandra
Lissandra brings significantly more crowd control than Pantheon, with 1.1 more seconds of CC per minute. This large utility gap makes Lissandra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Pantheon should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
821Pantheon
556Lissandra
Pantheon vastly out-sustains Lissandra, healing and mitigating 264 more damage per minute. This massive durability gap means Pantheon can absorb significant punishment and remain in lane while Lissandra is forced to recall. Building grievous wounds early is essential for Lissandra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Pantheon Build Against Lissandra

Mercury's Treads is the optimal boots choice against Lissandra, providing the mobility and stats Pantheon needs most in this matchup. The top-performing core items for Pantheon against Lissandra are Voltaic Cyclosword, Edge of Night and Kaenic Rookern. This combination gives Pantheon an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Lissandra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Pantheon vs Lissandra matchup.

Early Game vs Late Game

Early Game
Pantheon
75.0%
+50.0% advantage
Pantheon early game win ratePantheon75.0%
Lissandra early game win rateLissandra25.0%
Late Game
Lissandra
66.7%
+33.3% advantage
Pantheon late game win ratePantheon33.3%
Lissandra late game win rateLissandra66.7%

Pantheon dominates the early game (first 15 minutes) with a commanding 75.0% win rate — a 50.0 percentage point lead over Lissandra. This lopsided early game means Pantheon can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Lissandra is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Pantheon. Extended games heavily favor Lissandra, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Pantheon must aggressively press their early advantage and close out the game before Lissandra reaches their scaling breakpoints. If Lissandra survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Pantheon Runes Against Lissandra

Precision rune tree - Pantheon primary runes vs LissandraPrecision
Conqueror - best Pantheon rune vs LissandraTriumph - best Pantheon rune vs LissandraLegend: Haste - best Pantheon rune vs LissandraCoup de Grace - best Pantheon rune vs Lissandra
Domination rune tree - Pantheon secondary runes vs LissandraDomination
Cheap Shot - best Pantheon rune vs LissandraRelentless Hunter - best Pantheon rune vs Lissandra
50.0% WR

Running Precision primary with Domination secondary allows Pantheon to press their advantage against Lissandra, amplifying the strengths that make this a favorable matchup.


Pantheon matchup data for League of Legends patch 26.14. The table below shows Pantheon's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Pantheon build, runes, laning stats, and early vs late game analysis for that specific matchup.

Pantheon matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
43.98%1661.667810,07146.0%42.4%
53.80%1581.969811,01241.2%59.8%
52.13%941.666210,31461.5%45.5%
48.86%881.669210,32242.9%52.8%
48.86%884.988411,01050.0%48.1%
49.40%831.670310,23751.7%48.1%
50.63%795.392011,52244.1%55.6%
61.04%771.767610,52148.0%67.3%
53.95%761.671910,24058.8%50.0%
40.79%761.669510,67139.3%41.7%
52.05%735.490711,13355.9%48.7%
49.30%714.794710,06950.0%48.8%
53.62%691.46399,89661.3%47.4%
32.84%672.893011,18620.0%38.3%
43.94%661.56428,91648.5%39.4%
44.26%615.41,02512,54652.2%39.5%
55.00%604.592110,99864.0%48.6%
44.07%594.37309,58542.3%45.5%
57.41%541.665710,60652.9%59.5%
50.00%522.188712,37250.0%50.0%
53.06%492.681210,18650.0%54.8%
56.25%484.379110,60057.9%55.2%
58.33%484.383311,17261.1%56.7%
57.45%474.585110,85552.9%60.0%
44.68%472.17019,51045.8%43.5%
59.09%443.992912,42445.0%70.8%
46.51%431.767210,03750.0%44.0%
30.23%431.55918,12429.2%31.6%
58.14%433.783311,17060.0%57.1%
60.47%432.47019,98061.1%60.0%
60.47%431.56269,41364.7%57.7%
61.90%424.91,15912,41453.3%66.7%
39.02%411.45709,71843.8%36.0%
43.90%411.85898,57344.4%43.5%
29.27%411.972711,28223.5%33.3%
56.10%414.799512,37969.2%50.0%
45.00%401.86559,76753.3%40.0%
47.37%385.888111,05933.3%56.5%
60.53%385.691811,73053.3%65.2%
44.44%365.588011,14763.6%36.0%
34.29%353.176712,10366.7%23.1%
45.71%352.991411,46046.7%45.0%
48.48%332.682310,98050.0%47.6%
54.55%335.091111,90554.5%54.5%
40.63%321.173213,18457.1%36.0%
37.50%321.178412,45525.0%45.0%
53.33%302.472010,86060.0%46.7%
43.33%304.99019,95530.8%52.9%
56.67%301.166611,47353.3%60.0%
58.62%291.672110,27562.5%53.9%
41.38%295.378510,24530.0%47.4%
39.29%285.586610,43754.5%29.4%
64.29%285.391610,02258.3%68.8%
57.14%286.084710,70650.0%64.3%
50.00%284.478910,55441.7%56.3%
44.44%271.069011,95630.0%52.9%
33.33%275.081211,29346.1%21.4%
53.85%261.97209,56270.0%43.8%
42.31%264.87359,95438.5%46.1%
46.15%265.31,17411,16545.5%46.7%
46.15%263.888010,62225.0%55.6%
56.00%255.090011,58050.0%61.5%
52.00%255.51,04013,17242.9%55.6%
32.00%251.45808,17341.7%23.1%
56.00%251.675910,85555.6%56.3%
45.83%241.268713,33933.3%50.0%
34.78%233.67159,09427.3%41.7%
69.57%231.57139,69484.6%50.0%
39.13%231.175611,70450.0%35.3%
47.83%234.583112,12350.0%47.4%
50.00%221.573910,73550.0%50.0%
59.09%225.587910,90761.5%55.6%
45.45%223.579312,55925.0%50.0%
22.73%222.46519,14316.7%30.0%
50.00%225.094512,70133.3%56.3%
50.00%225.391210,57155.6%46.1%
40.91%222.585711,30427.3%54.5%
33.33%212.472010,13322.2%41.7%
61.90%211.170011,94857.1%64.3%
47.62%215.091111,26450.0%46.1%
60.00%201.983310,04075.0%50.0%
55.00%203.588510,01863.6%44.4%
30.00%202.075910,89533.3%28.6%
65.00%202.065510,57057.1%69.2%
52.63%192.681810,59742.9%58.3%
36.84%193.083410,47644.4%30.0%
73.68%194.987310,74680.0%66.7%
50.00%185.988211,46957.1%45.5%
52.94%171.783312,0650.0%64.3%
41.18%174.486712,06050.0%36.4%
50.00%165.489911,28962.5%37.5%
56.25%165.079111,36171.4%44.4%
25.00%161.081110,03337.5%12.5%
50.00%164.192710,24757.1%44.4%
56.25%165.28399,59387.5%25.0%
56.25%162.884114,8950.0%56.3%
40.00%151.86829,62140.0%40.0%
26.67%155.51,15212,21540.0%20.0%
35.71%144.274310,48025.0%40.0%
42.86%145.390311,19133.3%50.0%
50.00%145.597812,71350.0%50.0%
46.15%131.580714,58733.3%50.0%
38.46%131.577712,73220.0%50.0%
53.85%134.583612,39640.0%62.5%
83.33%126.01,11311,04680.0%85.7%
50.00%121.379313,43275.0%37.5%
58.33%125.292711,37850.0%62.5%
75.00%121.166610,586100.0%57.1%
45.45%114.389112,43075.0%28.6%
63.64%111.374511,71833.3%75.0%
54.55%115.99079,71183.3%20.0%
54.55%116.01,22612,93475.0%42.9%
70.00%102.679410,99050.0%83.3%
30.00%103.099710,80550.0%16.7%
40.00%100.871812,64625.0%50.0%
60.00%103.16299,85175.0%50.0%
50.00%103.093012,5940.0%62.5%
50.00%100.963011,67650.0%50.0%
50.00%100.772712,84866.7%42.9%
80.00%101.082511,667100.0%66.7%
77.78%96.11,02312,35975.0%80.0%
44.44%92.182912,28333.3%50.0%
44.44%93.686111,893100.0%28.6%
37.50%83.77419,44650.0%25.0%
50.00%85.591411,19925.0%75.0%
37.50%84.18149,90666.7%20.0%
50.00%83.893810,89433.3%60.0%
85.71%75.01,20011,85875.0%100.0%
57.14%75.083413,55166.7%50.0%
71.43%75.183610,16750.0%80.0%
57.14%73.873712,2480.0%66.7%
57.14%73.369410,42775.0%33.3%
50.00%64.776911,1640.0%60.0%
50.00%65.51,20415,0730.0%50.0%
50.00%60.953812,35150.0%50.0%
33.33%64.392213,4050.0%33.3%
80.00%51.888313,868100.0%75.0%
80.00%53.399214,27066.7%100.0%
40.00%51.882813,0350.0%50.0%
60.00%51.67499,33650.0%66.7%
40.00%54.893613,8280.0%40.0%

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Pantheon vs Lissandra - Frequently Asked Questions

How does Pantheon do against Lissandra in League of Legends?

Pantheon wins the Pantheon vs Lissandra matchup with a 57.1% win rate compared to Lissandra's 42.9%, a 14.3 percentage point difference. This data is based on 7 recent ranked games in patch 26.14.

How does Pantheon do against Lissandra in the early game?

In the early game, Pantheon has the advantage against Lissandra with a 75.0% win rate versus 25.0%. Pantheon players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Pantheon do against Lissandra in the late game?

In the late game, Lissandra takes over the Pantheon vs Lissandra matchup with a 66.7% win rate compared to 33.3%. Lissandra scales better into team fights and objective contests after 25 minutes.

Who wins the Pantheon vs Lissandra matchup?

Pantheon wins the matchup against Lissandra with a 57.1% win rate in League of Legends patch 26.14. The 14.3 percentage point advantage means Pantheon is significantly favored in this lane matchup based on 7 games analyzed.

What is the best Pantheon build against Lissandra?

The best Pantheon build against Lissandra includes Voltaic Cyclosword, Edge of Night, Kaenic Rookern with Mercury's Treads. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Pantheon runes against Lissandra?

The best Pantheon runes against Lissandra use the Precision primary tree with Domination secondary. This rune setup achieves a 50.0% win rate in the Pantheon vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.

Does Pantheon counter Lissandra?

Yes, Pantheon has a favorable matchup against Lissandra with a 57.1% win rate. Pantheon strongly counters Lissandra in lane based on current patch 26.14 data.

How do I play Pantheon against Lissandra?

When playing Pantheon against Lissandra, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.