Orianna - League of Legends Champion
Win Rate
47.5%
Pick Rate
1.5%

Oriannavs Vayne

FMageSupport
Patch26.10
Matches1,361,747
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 19, 2026
MethodologyData Methodology

Orianna vs Vayne is a decisive matchup in LoL patch 26.10. Orianna wins with a 80.0% win rate (+60.0%) over Vayne based on 5 games. Orianna holds the advantage in both the early and late game. Below you'll find the best Orianna build, runes, laning stats, and strategies for the Orianna vs Vayne matchup.

Orianna Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Orianna performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 80.0% win rateVayne(80.0%)
Orianna - 80.0% win rate in this matchup
Orianna
80.0% WR
VS
Vayne vs Orianna matchup - 20.0% win rate
Vayne
20.0% WR

Who Wins the Orianna vs Vayne Matchup?

Orianna wins the Orianna vs Vayne matchup
Winner
Orianna
Matches: 5
80.0%
Win Rate
20.0%
5.8
CS / min
6.5
611
DMG / min
752
8,559
Gold / game
8,883
96
Heal / min
213
347
DMG Mitigated / min
508
0.7
CC / min
0.4
75.0%
Early Game WR
25.0%
100.0%
Late Game WR
0.0%

Orianna vs Vayne Matchup Summary

The Orianna vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Orianna wins with a 80.0% win rate compared to Vayne's 20.0%, giving Orianna a 60.0 percentage point advantage. Orianna dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Orianna leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Orianna players can confidently pick into Vayne and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vayne away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Orianna vs Vayne Laning Phase Breakdown

Vayne wins the laning phase against Orianna in League of Legends

Vayne is favored during the laning phase against Orianna, winning 4 out of 5 key stat categories. Vayne holds advantages in farming, damage, gold income and sustain, making them the stronger laner in this matchup.

Farming
5.8Orianna
6.5Vayne
Vayne edges out Orianna by 0.7 CS per minute — a moderate farming advantage that adds up to roughly 11 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Vayne.
Damage
611Orianna
752Vayne
Vayne heavily out-damages Orianna by 141 DMG/min, dominating both short trades and all-in fights. Orianna should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
8,559Orianna
8,883Vayne
Vayne earns 324 more gold per game than Orianna, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Vayne slightly faster item completions.
Utility
0.7Orianna
0.4Vayne
Orianna provides 0.3 seconds more crowd control per minute than Vayne, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Orianna coordinate with their jungler and control the pace of skirmishes.
Sustain
442Orianna
722Vayne
Vayne vastly out-sustains Orianna, healing and mitigating 279 more damage per minute. This massive durability gap means Vayne can absorb significant punishment and remain in lane while Orianna is forced to recall. Building grievous wounds early is essential for Orianna, and focusing on burst trade patterns rather than sustained fights is critical.

Early Game vs Late Game

Early Game
Orianna
75.0%
+50.0% advantage
Orianna early game win rateOrianna75.0%
Vayne early game win rateVayne25.0%
Late Game
Orianna
100.0%
+100.0% advantage
Orianna late game win rateOrianna100.0%
Vayne late game win rateVayne0.0%

Orianna dominates the early game (first 15 minutes) with a commanding 75.0% win rate — a 50.0 percentage point lead over Vayne. This lopsided early game means Orianna can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Orianna is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Vayne. Extended games heavily favor Orianna, whose kit and scaling make them a dominant force in team fights and objective control.

Orianna holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Orianna Runes Against Vayne

Sorcery rune tree - Orianna primary runes vs VayneSorcery
Summon Aery - best Orianna rune vs VayneManaflow Band - best Orianna rune vs VayneTranscendence - best Orianna rune vs VayneScorch - best Orianna rune vs Vayne
Precision rune tree - Orianna secondary runes vs VaynePrecision
Presence of Mind - best Orianna rune vs VayneLegend: Haste - best Orianna rune vs Vayne
100.0% WR

Running Sorcery primary with Precision secondary allows Orianna to press their advantage against Vayne, amplifying the strengths that make this a favorable matchup.


Orianna matchup data for League of Legends patch 26.10. The table below shows Orianna's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Orianna build, runes, laning stats, and early vs late game analysis for that specific matchup.

Orianna matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
43.21%1626.979911,95842.7%43.7%
43.06%1446.876512,01636.7%46.3%
48.84%1296.778712,12143.5%51.8%
34.04%946.269610,98432.6%35.3%
48.35%916.875711,05443.2%53.2%
48.89%906.781511,74445.6%52.3%
40.91%886.476710,73528.9%50.0%
45.35%866.784211,73937.9%49.1%
46.15%786.771611,06546.1%46.1%
40.79%766.883410,90842.2%38.7%
53.42%736.480011,94051.5%55.0%
41.67%726.776210,53744.1%39.5%
39.13%696.677711,60226.7%48.7%
40.30%676.682011,45731.0%47.4%
48.44%646.577412,03841.4%54.3%
49.18%617.284511,41744.8%53.1%
47.46%596.798611,38553.3%41.4%
54.24%596.776911,19244.4%62.5%
46.30%546.878010,66041.9%52.2%
58.49%536.179811,44159.1%58.1%
36.00%506.773011,50127.8%40.6%
57.45%476.678011,48452.6%60.7%
44.44%456.484510,47739.1%50.0%
38.64%446.771010,95842.9%34.8%
51.16%437.072610,03855.6%43.8%
55.81%436.877011,03245.0%65.2%
48.78%416.481111,78550.0%47.6%
45.00%407.080211,33728.6%63.2%
58.97%396.48409,66854.5%64.7%
43.59%396.773211,61444.4%42.9%
54.05%376.676011,72660.0%50.0%
59.38%326.474411,23258.3%60.0%
48.28%296.877710,85950.0%46.7%
51.72%297.091512,41654.5%50.0%
35.71%286.892312,52110.0%50.0%
62.96%276.775312,76066.7%61.1%
56.00%257.389510,91361.5%50.0%
50.00%245.77479,49950.0%50.0%
43.48%236.682111,19144.4%42.9%
52.17%235.874310,13030.0%69.2%
47.62%216.468211,59942.9%50.0%
42.11%196.988311,71322.2%60.0%
47.37%195.976810,64850.0%42.9%
55.56%186.886511,89337.5%70.0%
38.89%186.979910,29440.0%37.5%
47.06%176.169411,15428.6%60.0%
73.33%156.61,03713,12280.0%70.0%
53.33%156.278011,15650.0%57.1%
53.33%156.888213,02285.7%25.0%
71.43%145.674610,42487.5%50.0%
28.57%143.257710,70042.9%14.3%
30.77%136.377210,71242.9%16.7%
70.00%102.04248,01371.4%66.7%
80.00%102.245510,93850.0%87.5%
60.00%107.579312,00150.0%66.7%
77.78%96.992813,73375.0%80.0%
33.33%94.558210,77933.3%33.3%
44.44%91.84137,62957.1%0.0%
37.50%85.576611,4040.0%60.0%
62.50%85.91,02911,11133.3%80.0%
0.00%86.08037,4100.0%0.0%
62.50%86.81,09812,121100.0%50.0%
75.00%85.782012,12475.0%75.0%
62.50%85.862210,30050.0%66.7%
25.00%87.47828,96033.3%0.0%
75.00%87.379310,69380.0%66.7%
57.14%76.885212,23950.0%66.7%
57.14%76.084214,112100.0%50.0%
14.29%76.593711,5010.0%20.0%
71.43%72.16219,98766.7%75.0%
42.86%71.53558,57825.0%66.7%
100.00%73.560310,121100.0%100.0%
71.43%76.61,00112,61266.7%75.0%
66.67%61.24399,993100.0%50.0%
33.33%65.61,03013,81233.3%33.3%
66.67%65.77759,17966.7%66.7%
66.67%66.384210,08366.7%66.7%
33.33%62.338210,73250.0%25.0%
100.00%66.665513,600100.0%100.0%
80.00%55.86118,55975.0%100.0%
40.00%56.55979,05033.3%50.0%
40.00%54.86089,67233.3%50.0%

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Orianna vs Vayne - Frequently Asked Questions

How does Orianna do against Vayne in League of Legends?

Orianna wins the Orianna vs Vayne matchup with a 80.0% win rate compared to Vayne's 20.0%, a 60.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.

How does Orianna do against Vayne in the early game?

In the early game, Orianna has the advantage against Vayne with a 75.0% win rate versus 25.0%. Orianna players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Orianna do against Vayne in the late game?

In the late game, Orianna takes over the Orianna vs Vayne matchup with a 100.0% win rate compared to 0.0%. Orianna scales better into team fights and objective contests after 25 minutes.

Who wins the Orianna vs Vayne matchup?

Orianna wins the matchup against Vayne with a 80.0% win rate in League of Legends patch 26.10. The 60.0 percentage point advantage means Orianna is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Orianna build against Vayne?

The best Orianna build against Vayne includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Orianna runes against Vayne?

The best Orianna runes against Vayne use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Orianna vs Vayne matchup. See the full rune breakdown in the matchup comparison above.

Does Orianna counter Vayne?

Yes, Orianna has a favorable matchup against Vayne with a 80.0% win rate. Orianna strongly counters Vayne in lane based on current patch 26.10 data.

How do I play Orianna against Vayne?

When playing Orianna against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.