Vayne - League of Legends Champion
Win Rate
49.9%
Pick Rate
5.2%

Vaynevs Orianna

BMarksmanAssassin
Patch26.10
Matches1,361,747
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 19, 2026
MethodologyData Methodology

Vayne vs Orianna is a decisive matchup in LoL patch 26.10. Orianna wins with a 80.0% win rate (+60.0%) over Vayne based on 5 games. Orianna holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Orianna matchup.

Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Orianna - 20.0% win rateOrianna(20.0%)
Vayne - 20.0% win rate in this matchup
Vayne
20.0% WR
VS
Orianna vs Vayne matchup - 80.0% win rate
Orianna
80.0% WR

Who Wins the Vayne vs Orianna Matchup?

Orianna wins the Vayne vs Orianna matchup
Winner
Orianna
Matches: 5
20.0%
Win Rate
80.0%
6.5
CS / min
5.8
752
DMG / min
611
8,883
Gold / game
8,559
213
Heal / min
96
508
DMG Mitigated / min
347
0.4
CC / min
0.7
25.0%
Early Game WR
75.0%
0.0%
Late Game WR
100.0%

Vayne vs Orianna Matchup Summary

The Vayne vs Orianna matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Orianna wins with a 80.0% win rate compared to Vayne's 20.0%, giving Orianna a 60.0 percentage point advantage. Orianna dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Orianna leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Orianna has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Orianna overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Orianna Laning Phase Breakdown

Vayne wins the laning phase against Orianna in League of Legends

Vayne is favored during the laning phase against Orianna, winning 4 out of 5 key stat categories. Vayne holds advantages in farming, damage, gold income and sustain, making them the stronger laner in this matchup.

Farming
6.5Vayne
5.8Orianna
Vayne edges out Orianna by 0.7 CS per minute — a moderate farming advantage that adds up to roughly 11 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Vayne.
Damage
752Vayne
611Orianna
Vayne heavily out-damages Orianna by 141 DMG/min, dominating both short trades and all-in fights. Orianna should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
8,883Vayne
8,559Orianna
Vayne earns 324 more gold per game than Orianna, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Vayne slightly faster item completions.
Utility
0.4Vayne
0.7Orianna
Orianna provides 0.3 seconds more crowd control per minute than Vayne, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Orianna coordinate with their jungler and control the pace of skirmishes.
Sustain
722Vayne
442Orianna
Vayne vastly out-sustains Orianna, healing and mitigating 279 more damage per minute. This massive durability gap means Vayne can absorb significant punishment and remain in lane while Orianna is forced to recall. Building grievous wounds early is essential for Orianna, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Orianna

Chainlaced Crushers is the optimal boots choice against Orianna, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Orianna are Voltaic Cyclosword, Umbral Glaive and Mortal Reminder. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Orianna. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Orianna matchup.

Early Game vs Late Game

Early Game
Orianna
75.0%
+50.0% advantage
Vayne early game win rateVayne25.0%
Orianna early game win rateOrianna75.0%
Late Game
Orianna
100.0%
+100.0% advantage
Vayne late game win rateVayne0.0%
Orianna late game win rateOrianna100.0%

Orianna dominates the early game (first 15 minutes) with a commanding 75.0% win rate — a 50.0 percentage point lead over Vayne. This lopsided early game means Orianna can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Orianna is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Vayne. Extended games heavily favor Orianna, whose kit and scaling make them a dominant force in team fights and objective control.

Orianna holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Vayne Runes Against Orianna

Domination rune tree - Vayne primary runes vs OriannaDomination
Hail of Blades - best Vayne rune vs OriannaSudden Impact - best Vayne rune vs OriannaGrisly Mementos - best Vayne rune vs OriannaUltimate Hunter - best Vayne rune vs Orianna
Precision rune tree - Vayne secondary runes vs OriannaPrecision
Coup de Grace - best Vayne rune vs OriannaLegend: Bloodline - best Vayne rune vs Orianna
100.0% WR

The Domination and Precision rune setup gives Vayne the best tools to compete against Orianna in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Vayne matchup data for League of Legends patch 26.10. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
43.15%8696.188113,42442.8%43.4%
47.85%6736.079012,84346.5%48.8%
45.71%6306.081912,95944.4%46.8%
54.01%5246.284913,32452.6%55.1%
52.37%5066.081313,01650.7%53.5%
48.66%4855.776212,22346.6%50.4%
51.05%3806.285513,00348.0%53.7%
53.72%3096.390513,51747.5%58.9%
54.67%2146.188613,04254.6%54.7%
50.49%2066.081612,39444.8%55.5%
45.27%2015.978113,41949.4%42.5%
48.22%1976.082413,42947.4%48.8%
47.34%1696.377112,79448.8%46.1%
55.69%1676.596712,40557.1%54.6%
50.30%1656.081613,13446.1%54.0%
44.85%1655.978912,39443.5%45.8%
42.04%1575.660610,83837.1%46.0%
49.01%1516.784413,47045.2%51.7%
58.78%1486.388811,67850.0%65.5%
56.25%1446.092011,48454.8%57.3%
47.69%1305.980113,28740.7%52.6%
32.26%1245.757710,44322.2%40.0%
51.26%1196.282112,85846.8%56.1%
48.70%1156.383613,14054.5%45.1%
41.96%1126.389512,77840.0%43.5%
47.75%1115.991711,84556.3%41.3%
54.81%1046.083512,19055.1%54.5%
41.75%1035.986413,38435.9%45.3%
54.08%986.61,13613,35544.2%61.8%
53.33%906.271710,50748.8%57.5%
47.06%855.789611,33345.0%48.9%
42.68%826.11,27011,83738.9%45.6%
56.52%696.688111,66350.0%62.9%
41.79%676.292212,16534.8%45.5%
58.21%675.81,10012,33455.6%60.0%
59.09%666.887312,12456.7%61.1%
43.94%666.397612,39759.3%33.3%
54.10%616.286412,01063.0%47.1%
48.33%606.397811,86454.5%44.7%
58.62%586.51,00712,50869.2%50.0%
46.43%566.086511,11038.7%56.0%
62.50%566.288011,96961.5%63.3%
58.49%536.31,05013,88652.4%62.5%
46.15%525.782613,09344.4%47.1%
42.00%506.181512,67056.3%35.3%
56.00%505.881012,20861.1%53.1%
64.00%506.485912,80872.7%57.1%
48.98%496.579411,89153.6%42.9%
52.08%486.01,01611,72952.4%51.9%
55.32%476.173512,81655.0%55.6%
50.00%466.394713,31152.4%48.0%
52.27%446.285511,93948.1%58.8%
55.81%435.281011,90945.0%65.2%
55.81%436.189912,90342.9%68.2%
53.66%416.293211,34360.9%44.4%
41.46%415.578912,33646.7%38.5%
63.16%386.299112,59246.1%72.0%
45.95%376.487612,63244.4%47.4%
55.56%366.293211,04338.1%80.0%
63.89%364.284711,28761.9%66.7%
36.11%365.668910,09931.6%41.2%
51.43%356.184212,53453.3%50.0%
57.14%356.396311,53756.3%57.9%
47.06%345.184912,52033.3%54.5%
67.65%346.171712,13866.7%68.4%
51.52%336.575812,35557.1%47.4%
50.00%326.070511,31158.8%40.0%
40.63%326.389012,53931.3%50.0%
54.84%316.180112,60550.0%57.1%
46.67%306.01,01212,58850.0%44.4%
44.83%296.398611,55145.5%44.4%
48.28%296.489813,85441.7%52.9%
48.15%275.669611,17541.7%53.3%
48.15%275.371910,01935.3%70.0%
59.26%275.774912,64454.5%62.5%
42.31%266.096513,44720.0%47.6%
50.00%266.588012,57350.0%50.0%
56.00%255.281111,56938.5%75.0%
24.00%256.069611,67216.7%30.8%
45.83%245.876310,28641.7%50.0%
43.48%236.082212,80530.0%53.9%
40.91%224.769411,78245.5%36.4%
40.91%226.187411,62350.0%33.3%
59.09%223.21,00613,64863.6%54.5%
61.90%216.388614,11057.1%64.3%
31.58%196.31,04411,85822.2%40.0%
33.33%186.076411,76728.6%36.4%
47.06%176.082613,30225.0%53.9%
35.29%176.260910,41444.4%25.0%
52.94%174.21,08013,54450.0%55.6%
47.06%176.51,04512,79440.0%50.0%
56.25%166.71,02512,42571.4%44.4%
56.25%166.091814,3370.0%64.3%
50.00%166.789612,79855.6%42.9%
33.33%156.371310,67562.5%0.0%
57.14%145.971511,03642.9%71.4%
61.54%134.587512,07237.5%100.0%
66.67%125.91,03311,79671.4%60.0%
54.55%114.61,02014,29766.7%50.0%
72.73%115.587213,36260.0%83.3%
27.27%113.655611,17750.0%14.3%
45.45%112.977712,07350.0%42.9%
45.45%113.583711,90940.0%50.0%
45.45%115.91,01412,55550.0%44.4%
45.45%113.181214,07920.0%66.7%
45.45%115.192012,92433.3%50.0%
60.00%102.55799,61742.9%100.0%
50.00%106.181310,09342.9%66.7%
50.00%104.571514,1370.0%55.6%
44.44%92.78729,71933.3%66.7%
33.33%92.572112,37620.0%50.0%
44.44%96.799110,35560.0%25.0%
55.56%93.71,00314,542100.0%50.0%
75.00%84.51,07215,357100.0%71.4%
25.00%86.582013,32025.0%25.0%
42.86%75.766911,682100.0%33.3%
57.14%71.479612,46666.7%50.0%
50.00%64.399614,68650.0%50.0%
66.67%66.91,18714,237100.0%33.3%
50.00%62.687612,3100.0%60.0%
50.00%63.990214,77450.0%50.0%
16.67%61.069413,42133.3%0.0%
20.00%55.26959,22225.0%0.0%
40.00%54.472112,97950.0%33.3%
40.00%55.97827,8020.0%100.0%
20.00%56.88278,48825.0%0.0%
80.00%56.269210,724100.0%50.0%
80.00%54.890313,95450.0%100.0%
20.00%56.57528,88325.0%0.0%

Get the MetaBot Desktop App

Level up your gameplay with real-time overlays, automatic game detection, and instant stats — all on your desktop.

In-game overlaysAuto game detectionMulti-game supportPersonal dashboard
Download NowFree download
🔍

Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.

Report an Issue

Vayne vs Orianna - Frequently Asked Questions

How does Vayne do against Orianna in League of Legends?

Orianna wins the Vayne vs Orianna matchup with a 80.0% win rate compared to Vayne's 20.0%, a 60.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.

How does Vayne do against Orianna in the early game?

In the early game, Orianna has the advantage against Vayne with a 75.0% win rate versus 25.0%. Orianna players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Orianna in the late game?

In the late game, Orianna takes over the Vayne vs Orianna matchup with a 100.0% win rate compared to 0.0%. Orianna scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Orianna matchup?

Orianna wins the matchup against Vayne with a 80.0% win rate in League of Legends patch 26.10. The 60.0 percentage point advantage means Orianna is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Vayne build against Orianna?

The best Vayne build against Orianna includes Voltaic Cyclosword, Umbral Glaive, Mortal Reminder with Chainlaced Crushers. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Orianna?

The best Vayne runes against Orianna use the Domination primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Orianna matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Orianna?

No, Vayne struggles against Orianna with only a 20.0% win rate. Orianna has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Orianna's lead.

How do I play Vayne against Orianna?

When playing Vayne against Orianna, play cautiously and avoid Orianna's power spikes. Look for jungle assistance and team-dependent plays since Orianna has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.