Seraphine - League of Legends Champion
Win Rate
51.8%
Pick Rate
4.8%

Seraphinevs Syndra

SSupportMage
Patch26.7
Matches508,082
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 15, 2026
MethodologyData Methodology

Seraphine vs Syndra is a decisive matchup in LoL patch 26.7. Syndra wins with a 60.0% win rate (+20.0%) over Seraphine based on 5 games. Syndra wins the early laning phase while Seraphine scales better into the late game. Below you'll find the best Seraphine build, runes, laning stats, and strategies for the Seraphine vs Syndra matchup.

Seraphine Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Seraphine performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Syndra - 40.0% win rateSyndra(40.0%)
Seraphine - 40.0% win rate in this matchup
Seraphine
40.0% WR
VS
Syndra vs Seraphine matchup - 60.0% win rate
Syndra
60.0% WR

Who Wins the Seraphine vs Syndra Matchup?

Syndra wins the Seraphine vs Syndra matchup
Winner
Syndra
Matches: 5
40.0%
Win Rate
60.0%
6.0
CS / min
7.3
777
DMG / min
956
11,015
Gold / game
12,897
157
Heal / min
114
496
DMG Mitigated / min
340
1.6
CC / min
1.4
33.3%
Early Game WR
66.7%
50.0%
Late Game WR
50.0%

Seraphine vs Syndra Matchup Summary

The Seraphine vs Syndra matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Syndra wins with a 60.0% win rate compared to Seraphine's 40.0%, giving Syndra a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Syndra controls the early laning stage, but Seraphine outscales as the game goes longer. The matchup shifts dramatically depending on game length — Syndra needs to press advantages before Seraphine reaches their power spikes, while Seraphine should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Seraphine leads by 199 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra has a strong advantage in this matchup. Seraphine players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Syndra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Seraphine vs Syndra Laning Phase Breakdown

Syndra wins the laning phase against Seraphine in League of Legends

Syndra is favored during the laning phase against Seraphine, winning 3 out of 5 key stat categories. Syndra holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
6.0Seraphine
7.3Syndra
Syndra significantly out-farms Seraphine by 1.3 CS per minute, accumulating an estimated 20 CS lead by mid game. This substantial farming gap gives Syndra a major gold advantage and earlier item completions. Seraphine players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
777Seraphine
956Syndra
Syndra heavily out-damages Seraphine by 179 DMG/min, dominating both short trades and all-in fights. Seraphine should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Syndra's sustained damage advantage take over.
Economy
11,015Seraphine
12,897Syndra
Syndra generates a commanding 1,882 more gold per game than Seraphine. This substantial economic advantage means Syndra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Seraphine should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.6Seraphine
1.4Syndra
Both Seraphine and Syndra provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
653Seraphine
454Syndra
Seraphine vastly out-sustains Syndra, healing and mitigating 199 more damage per minute. This massive durability gap means Seraphine can absorb significant punishment and remain in lane while Syndra is forced to recall. Building grievous wounds early is essential for Syndra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Seraphine Build Against Syndra

Crimson Lucidity is the optimal boots choice against Syndra, providing the mobility and stats Seraphine needs most in this matchup. The top-performing core items for Seraphine against Syndra are Luden's Echo, Liandry's Torment and Rylai's Crystal Scepter. This combination gives Seraphine an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Syndra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Seraphine vs Syndra matchup.

Early Game vs Late Game

Early Game
Syndra
66.7%
+33.3% advantage
Seraphine early game win rateSeraphine33.3%
Syndra early game win rateSyndra66.7%
Late Game
Seraphine
50.0%
+0.0% advantage
Seraphine late game win rateSeraphine50.0%
Syndra late game win rateSyndra50.0%

Syndra dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Seraphine. This lopsided early game means Syndra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Seraphine at 50.0% win rate — only 0.0 points ahead of Syndra. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

The power dynamics shift as the game progresses — Syndra has the edge early, but Seraphine gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Seraphine Runes Against Syndra

Sorcery rune tree - Seraphine primary runes vs SyndraSorcery
Summon Aery - best Seraphine rune vs SyndraManaflow Band - best Seraphine rune vs SyndraTranscendence - best Seraphine rune vs SyndraScorch - best Seraphine rune vs Syndra
Inspiration rune tree - Seraphine secondary runes vs SyndraInspiration
Biscuit Delivery - best Seraphine rune vs SyndraCosmic Insight - best Seraphine rune vs Syndra
100.0% WR

The Sorcery and Inspiration rune setup gives Seraphine the best tools to compete against Syndra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Seraphine matchup data for League of Legends patch 26.7. The table below shows Seraphine's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Seraphine build, runes, laning stats, and early vs late game analysis for that specific matchup.

Seraphine matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
54.18%2991.64439,72745.0%59.6%
44.49%2631.34388,73041.4%48.0%
53.94%2411.34619,24352.6%55.2%
53.01%1831.44589,30748.8%56.4%
53.59%1811.44469,09849.4%57.5%
53.66%1641.44779,15159.3%48.2%
51.57%1591.54879,18454.3%49.4%
56.96%1581.44609,12365.1%51.6%
51.45%1381.44108,92450.8%52.1%
57.58%1321.44559,01657.4%57.8%
44.44%1261.34078,50942.9%46.0%
48.72%1171.655210,13343.2%51.3%
55.17%1161.54939,75339.1%65.7%
48.28%1161.754110,06752.2%45.7%
54.29%1051.34268,52558.2%50.0%
47.57%1031.54449,60136.6%54.8%
53.92%1021.44648,93753.9%54.0%
50.50%1011.43578,58654.9%46.0%
65.31%982.04699,74265.0%65.5%
51.11%901.45449,00546.1%54.9%
60.67%891.45258,87651.2%69.6%
48.05%771.64329,06447.1%48.8%
48.48%661.64499,83052.0%46.3%
56.06%661.446210,05756.0%56.1%
59.09%661.34709,19553.3%63.9%
51.52%661.45339,38642.9%57.9%
50.00%561.34318,78350.0%50.0%
50.91%555.059410,15445.7%60.0%
61.11%541.45039,73561.1%61.1%
45.10%511.45549,19748.0%42.3%
56.00%501.64589,66571.4%44.8%
68.09%471.34338,79683.3%52.2%
41.30%461.44408,44340.7%42.1%
55.26%386.575312,73061.1%50.0%
41.67%361.55229,34566.7%23.8%
45.71%351.45389,51041.2%50.0%
51.43%356.577612,68062.5%42.1%
41.18%341.95239,70342.9%40.0%
62.50%324.466312,14861.5%63.2%
61.54%261.45069,89770.0%56.3%
57.69%265.866912,09666.7%50.0%
72.00%253.654911,21477.8%68.8%
47.83%231.34387,54662.5%14.3%
39.13%231.34279,80042.9%37.5%
45.45%225.768813,31257.1%40.0%
42.86%212.04569,77930.0%54.5%
60.00%206.873212,63062.5%58.3%
68.42%192.25288,37271.4%60.0%
52.63%194.566310,72362.5%45.5%
77.78%185.262111,90780.0%75.0%
50.00%182.23929,53214.3%72.7%
17.65%171.95419,5550.0%30.0%
68.75%166.175711,132100.0%44.4%
56.25%165.061711,17950.0%58.3%
37.50%161.44408,74328.6%44.4%
40.00%155.879112,89180.0%20.0%
53.33%152.65158,83558.3%33.3%
60.00%156.969012,35375.0%42.9%
57.14%141.65038,97662.5%50.0%
50.00%126.066912,17266.7%33.3%
58.33%121.95109,80057.1%60.0%
41.67%124.362911,9680.0%50.0%
50.00%125.572511,57837.5%75.0%
45.45%111.83348,40757.1%25.0%
45.45%111.448611,0260.0%50.0%
20.00%101.94449,6570.0%40.0%
30.00%106.083411,91850.0%16.7%
66.67%95.04869,88271.4%50.0%
66.67%96.791812,31350.0%100.0%
44.44%91.652310,69633.3%50.0%
66.67%95.06849,58460.0%75.0%
55.56%95.878611,74075.0%40.0%
62.50%86.375213,234100.0%50.0%
62.50%84.164710,851100.0%0.0%
62.50%86.072611,59850.0%75.0%
50.00%81.63948,88825.0%75.0%
50.00%82.659011,57450.0%50.0%
37.50%84.34689,60866.7%20.0%
50.00%86.075212,12750.0%50.0%
75.00%81.84619,71750.0%100.0%
50.00%84.75939,70720.0%100.0%
28.57%71.54699,3480.0%50.0%
57.14%72.24578,64566.7%50.0%
85.71%71.55068,91275.0%100.0%
42.86%71.44499,4630.0%60.0%
50.00%63.866510,38850.0%50.0%
50.00%61.253910,07150.0%50.0%
50.00%62.45769,27866.7%33.3%
50.00%65.060611,31766.7%33.3%
40.00%56.077711,01533.3%50.0%
20.00%55.151210,8920.0%25.0%
60.00%55.872310,033100.0%50.0%
20.00%51.43949,2580.0%33.3%
80.00%54.677910,15775.0%100.0%
40.00%52.76589,47233.3%50.0%

Get the MetaBot Desktop App

Level up your gameplay with real-time overlays, automatic game detection, and instant stats — all on your desktop.

In-game overlaysAuto game detectionMulti-game supportPersonal dashboard
Download NowFree download
🔍

Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.

Report an Issue

Seraphine vs Syndra - Frequently Asked Questions

How does Seraphine do against Syndra in League of Legends?

Syndra wins the Seraphine vs Syndra matchup with a 60.0% win rate compared to Seraphine's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.7.

How does Seraphine do against Syndra in the early game?

In the early game, Syndra has the advantage against Seraphine with a 66.7% win rate versus 33.3%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Seraphine do against Syndra in the late game?

In the late game, Seraphine takes over the Seraphine vs Syndra matchup with a 50.0% win rate compared to 50.0%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Seraphine vs Syndra matchup?

Syndra wins the matchup against Seraphine with a 60.0% win rate in League of Legends patch 26.7. The 20.0 percentage point advantage means Syndra is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Seraphine build against Syndra?

The best Seraphine build against Syndra includes Luden's Echo, Liandry's Torment, Rylai's Crystal Scepter with Crimson Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Seraphine runes against Syndra?

The best Seraphine runes against Syndra use the Sorcery primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Seraphine vs Syndra matchup. See the full rune breakdown in the matchup comparison above.

Does Seraphine counter Syndra?

No, Seraphine struggles against Syndra with only a 40.0% win rate. Syndra has the advantage in this matchup. Seraphine players should focus on safe farming and avoiding extended trades to minimize Syndra's lead.

How do I play Seraphine against Syndra?

When playing Seraphine against Syndra, play cautiously and avoid Syndra's power spikes. Focus on safe farming — you outscale Syndra in the late game. Use the matchup-specific build and runes above to optimize your chances.