Seraphine - League of Legends Champion
Win Rate
51.4%
Pick Rate
7.6%

Seraphinevs Syndra

ASupportMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 2, 2026
MethodologyData Methodology

Seraphine vs Syndra is a decisive matchup in LoL patch 26.11. Syndra wins with a 69.2% win rate (+38.5%) over Seraphine based on 13 games. Syndra holds the advantage in both the early and late game. Below you'll find the best Seraphine build, runes, laning stats, and strategies for the Seraphine vs Syndra matchup.

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Seraphine Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Seraphine performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 30.8% win rate in this matchup
Seraphine
30.8% WR
VS
Syndra vs Seraphine matchup - 69.2% win rate
Syndra
69.2% WR

Who Wins the Seraphine vs Syndra Matchup?

Syndra wins the Seraphine vs Syndra matchup
Winner
Syndra
Matches: 13
30.8%
Win Rate
69.2%
4.1
CS / min
4.8
603
DMG / min
935
9,877
Gold / game
12,624
186
Heal / min
88
359
DMG Mitigated / min
323
1.0
CC / min
1.5
33.3%
Early Game WR
66.7%
28.6%
Late Game WR
71.4%

Seraphine vs Syndra Matchup Summary

The Seraphine vs Syndra matchup is a decisive matchup in League of Legends ranked play. Based on 13 recent matches analyzed, Syndra wins with a 69.2% win rate compared to Seraphine's 30.8%, giving Syndra a 38.5 percentage point advantage. Syndra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Seraphine players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in damage output, where Syndra leads by 332 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra has a strong advantage in this matchup. Seraphine players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Syndra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Seraphine vs Syndra Laning Phase Breakdown

Syndra wins the laning phase against Seraphine in League of Legends

Syndra is favored during the laning phase against Seraphine, winning 4 out of 5 key stat categories. Syndra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
4.1Seraphine
4.8Syndra
Syndra edges out Seraphine by 0.6 CS per minute — a moderate farming advantage that adds up to roughly 10 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Syndra.
Damage
603Seraphine
935Syndra
Syndra heavily out-damages Seraphine by 332 DMG/min, dominating both short trades and all-in fights. Seraphine should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Syndra's sustained damage advantage take over.
Economy
9,877Seraphine
12,624Syndra
Syndra generates a commanding 2,747 more gold per game than Seraphine. This substantial economic advantage means Syndra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Seraphine should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.0Seraphine
1.5Syndra
Syndra provides 0.5 seconds more crowd control per minute than Seraphine, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Syndra coordinate with their jungler and control the pace of skirmishes.
Sustain
545Seraphine
412Syndra
Seraphine heals and mitigates 133 more damage per minute than Syndra, providing moderate extra durability. This sustain edge allows Seraphine to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Syndra.

Best Seraphine Build Against Syndra

Crimson Lucidity is the optimal boots choice against Syndra, providing the mobility and stats Seraphine needs most in this matchup. The top-performing core items for Seraphine against Syndra are Rylai's Crystal Scepter, Seraph's Embrace and Blackfire Torch. This combination gives Seraphine an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Seraphine vs Syndra matchup.

Early Game vs Late Game

Early Game
Syndra
66.7%
+33.3% advantage
Seraphine early game win rateSeraphine33.3%
Syndra early game win rateSyndra66.7%
Late Game
Syndra
71.4%
+42.9% advantage
Seraphine late game win rateSeraphine28.6%
Syndra late game win rateSyndra71.4%

Syndra dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Seraphine. This lopsided early game means Syndra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Syndra is far superior in the late game (25+ minutes), boasting a 71.4% win rate — 42.9 points above Seraphine. Extended games heavily favor Syndra, whose kit and scaling make them a dominant force in team fights and objective control.

Syndra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Seraphine players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Seraphine Runes Against Syndra

Sorcery rune tree - Seraphine primary runes vs SyndraSorcery
Deathfire Touch - best Seraphine rune vs SyndraManaflow Band - best Seraphine rune vs SyndraTranscendence - best Seraphine rune vs SyndraScorch - best Seraphine rune vs Syndra
Precision rune tree - Seraphine secondary runes vs SyndraPrecision
Legend: Haste - best Seraphine rune vs SyndraCoup de Grace - best Seraphine rune vs Syndra
100.0% WR

The Sorcery and Precision rune setup gives Seraphine the best tools to compete against Syndra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Seraphine matchup data for League of Legends patch 26.11. The table below shows Seraphine's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Seraphine build, runes, laning stats, and early vs late game analysis for that specific matchup.

Seraphine matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.75%7791.74669,35944.9%49.5%
50.91%5501.44939,17358.0%45.0%
49.45%5481.44879,00751.2%48.0%
50.83%5431.44879,19746.8%53.9%
52.69%5011.54979,35248.8%55.5%
50.21%4781.85269,25551.6%49.0%
48.69%4211.54709,01249.2%48.3%
50.00%3341.44539,01050.4%49.7%
50.91%3301.95249,71553.4%49.2%
51.72%3191.44699,56046.7%55.4%
52.44%3071.44938,93052.7%52.2%
53.17%2841.74839,53147.7%56.6%
52.84%2821.44878,90149.2%55.8%
50.78%2581.54449,24750.5%51.0%
47.97%2461.54669,32744.7%50.4%
54.85%2371.85849,76454.8%54.9%
54.85%2371.44528,96551.9%57.4%
53.07%2281.53918,66358.8%46.8%
54.63%2271.84989,66455.6%54.0%
43.13%2111.35028,90135.6%48.8%
52.22%2031.45229,03758.4%47.4%
43.22%1991.54988,96147.1%40.4%
48.44%1921.44979,41851.2%46.3%
53.45%1741.84629,23249.4%56.7%
49.70%1691.66149,70344.4%52.2%
52.26%1551.44799,11856.9%48.2%
57.53%1461.45699,69067.9%51.1%
54.48%1454.566211,52162.3%50.0%
52.52%1391.44899,05164.1%42.7%
61.29%1241.64819,07567.7%54.8%
50.00%1221.44628,51250.8%49.1%
50.00%1201.45089,23252.8%47.8%
51.30%1151.44638,90542.2%57.1%
59.13%1156.281412,23054.7%62.9%
53.49%861.54809,03567.5%41.3%
54.88%825.867711,89860.0%51.9%
61.25%804.878912,00275.9%52.9%
56.76%746.880712,47863.9%50.0%
53.42%732.05109,99152.0%54.2%
56.16%731.55149,44956.8%55.6%
46.88%641.54679,51052.0%43.6%
43.33%601.65579,12160.7%28.1%
48.33%602.14408,59548.3%48.4%
54.24%596.283112,84042.1%60.0%
54.24%593.359210,05860.9%50.0%
60.34%585.375111,90651.9%67.7%
63.16%572.056710,73279.0%55.3%
44.23%521.75759,42052.0%37.0%
51.06%472.04629,10847.6%53.9%
50.00%402.260810,02652.6%47.6%
56.76%376.389112,39562.5%52.4%
44.44%362.55159,08730.8%52.2%
60.61%334.259811,53455.6%62.5%
51.52%335.366611,60061.5%45.0%
42.42%336.281310,73542.1%42.9%
51.52%336.878711,42658.8%43.8%
65.63%321.64749,16373.3%58.8%
65.63%324.168110,15666.7%64.7%
58.06%311.64859,79966.7%52.6%
56.67%306.673310,93362.5%50.0%
41.38%291.45019,36630.8%50.0%
44.44%275.167710,72263.6%31.3%
62.96%271.649810,32862.5%63.2%
54.17%244.26249,65645.5%61.5%
50.00%222.45679,74940.0%58.3%
45.45%223.04909,41825.0%57.1%
63.64%222.250811,56760.0%64.7%
40.00%206.580113,55633.3%41.2%
55.00%206.779212,47966.7%45.5%
55.00%202.04629,45857.1%53.9%
45.00%205.871411,07240.0%50.0%
70.00%201.464510,69887.5%58.3%
63.16%191.443410,16060.0%64.3%
61.11%185.67038,05964.3%50.0%
58.82%176.286512,02650.0%63.6%
35.29%171.244610,23775.0%23.1%
75.00%166.791813,62771.4%77.8%
37.50%161.54798,92840.0%36.4%
60.00%156.776112,98866.7%55.6%
40.00%155.359710,54633.3%44.4%
60.00%151.646310,50775.0%54.5%
50.00%143.264710,32850.0%50.0%
50.00%142.65519,74250.0%50.0%
42.86%144.85849,77450.0%37.5%
53.85%136.392112,20066.7%42.9%
30.77%134.16039,87733.3%28.6%
61.54%133.15949,46842.9%83.3%
58.33%126.78259,19670.0%0.0%
50.00%124.36669,42433.3%66.7%
58.33%126.076411,19160.0%57.1%
72.73%116.175811,907100.0%66.7%
27.27%114.55499,3630.0%50.0%
54.55%116.266011,06050.0%60.0%
60.00%105.680311,24250.0%75.0%
80.00%101.44777,16187.5%50.0%
66.67%94.552110,244100.0%62.5%
44.44%91.84238,69366.7%33.3%
37.50%86.293011,95740.0%33.3%
62.50%81.66239,74233.3%80.0%
37.50%81.53958,01025.0%50.0%
37.50%81.34679,59625.0%50.0%
25.00%85.367010,06850.0%16.7%
25.00%83.45779,67325.0%25.0%
62.50%81.457011,7740.0%71.4%
75.00%85.470711,28850.0%83.3%
50.00%81.14638,69050.0%50.0%
50.00%86.298713,25366.7%40.0%
75.00%81.648710,73550.0%83.3%
85.71%71.45378,417100.0%0.0%
42.86%71.949210,03133.3%50.0%
71.43%73.163510,657100.0%60.0%
57.14%73.473912,184100.0%50.0%
100.00%73.15957,466100.0%100.0%
71.43%73.05208,01175.0%66.7%
33.33%67.382210,97625.0%50.0%
100.00%62.35489,903100.0%100.0%
83.33%62.247410,918100.0%80.0%
50.00%61.63829,86350.0%50.0%
100.00%55.957011,5490.0%100.0%
40.00%51.649610,44750.0%33.3%
60.00%51.256510,3000.0%75.0%
40.00%56.06469,77425.0%100.0%
40.00%53.864610,54966.7%0.0%
80.00%51.549910,15550.0%100.0%

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Seraphine vs Syndra - Frequently Asked Questions

How does Seraphine do against Syndra in League of Legends?

Syndra wins the Seraphine vs Syndra matchup with a 69.2% win rate compared to Seraphine's 30.8%, a 38.5 percentage point difference. This data is based on 13 recent ranked games in patch 26.11.

How does Seraphine do against Syndra in the early game?

In the early game, Syndra has the advantage against Seraphine with a 66.7% win rate versus 33.3%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Seraphine do against Syndra in the late game?

In the late game, Syndra takes over the Seraphine vs Syndra matchup with a 71.4% win rate compared to 28.6%. Syndra scales better into team fights and objective contests after 25 minutes.

Who wins the Seraphine vs Syndra matchup?

Syndra wins the matchup against Seraphine with a 69.2% win rate in League of Legends patch 26.11. The 38.5 percentage point advantage means Syndra is significantly favored in this lane matchup based on 13 games analyzed.

What is the best Seraphine build against Syndra?

The best Seraphine build against Syndra includes Rylai's Crystal Scepter, Seraph's Embrace, Blackfire Torch with Crimson Lucidity. Check the matchup breakdown above for the full item path and build order.

What are the best Seraphine runes against Syndra?

The best Seraphine runes against Syndra use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Seraphine vs Syndra matchup. See the full rune breakdown in the matchup comparison above.

Does Seraphine counter Syndra?

No, Seraphine struggles against Syndra with only a 30.8% win rate. Syndra has the advantage in this matchup. Seraphine players should focus on safe farming and avoiding extended trades to minimize Syndra's lead.

How do I play Seraphine against Syndra?

When playing Seraphine against Syndra, play cautiously and avoid Syndra's power spikes. Look for jungle assistance and team-dependent plays since Syndra has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.