
Zoevs Lissandra
Zoe vs Lissandra is a decisive matchup in LoL patch 26.14. Lissandra wins with a 57.1% win rate (+14.3%) over Zoe based on 14 games. Lissandra holds the advantage in both the early and late game. Below you'll find the best Zoe build, runes, laning stats, and strategies for the Zoe vs Lissandra matchup.
Zoe Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Zoe performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Zoe vs Lissandra Matchup?

Zoe vs Lissandra Matchup Summary
The Zoe vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 14 recent matches analyzed, Lissandra wins with a 57.1% win rate compared to Zoe's 42.9%, giving Lissandra a 14.3 percentage point advantage. Lissandra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Zoe players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Lissandra leads by 0.4s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra has a strong advantage in this matchup. Zoe players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Lissandra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Zoe vs Lissandra Laning Phase Breakdown
Lissandra is favored during the laning phase against Zoe, winning 4 out of 5 key stat categories. Lissandra holds advantages in farming, gold income, crowd control and sustain, making them the stronger laner in this matchup.
Best Zoe Build Against Lissandra
Crimson Lucidity is the optimal boots choice against Lissandra, providing the mobility and stats Zoe needs most in this matchup. The top-performing core items for Zoe against Lissandra are Luden's Echo, Shadowflame and Lich Bane. This combination gives Zoe an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Lissandra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Zoe vs Lissandra matchup.
Early Game vs Late Game
Lissandra dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Zoe. This lopsided early game means Lissandra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Lissandra is far superior in the late game (25+ minutes), boasting a 54.5% win rate — 9.1 points above Zoe. Extended games heavily favor Lissandra, whose kit and scaling make them a dominant force in team fights and objective control.
Lissandra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Zoe players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Zoe Runes Against Lissandra
The Domination and Sorcery rune setup gives Zoe the best tools to compete against Lissandra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Zoe matchup data for League of Legends patch 26.14. The table below shows Zoe's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zoe build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 50.57% | 87 | 4.1 | 806 | 11,041 | 50.0% | 50.9% | |
| 46.75% | 77 | 5.7 | 932 | 10,372 | 43.2% | 50.0% | |
| 45.90% | 61 | 5.2 | 934 | 11,560 | 70.6% | 36.4% | |
| 56.67% | 60 | 5.6 | 920 | 10,975 | 61.9% | 53.9% | |
| 50.00% | 54 | 5.5 | 1,006 | 10,332 | 57.7% | 42.9% | |
| 52.83% | 53 | 5.8 | 863 | 11,161 | 55.0% | 51.5% | |
| 50.00% | 50 | 5.5 | 819 | 9,887 | 55.0% | 46.7% | |
| 56.41% | 39 | 5.0 | 901 | 11,411 | 44.4% | 60.0% | |
| 56.41% | 39 | 5.5 | 851 | 11,175 | 15.4% | 76.9% | |
| 35.90% | 39 | 5.8 | 844 | 11,211 | 58.3% | 25.9% | |
| 50.00% | 38 | 4.9 | 928 | 10,530 | 81.8% | 37.0% | |
| 51.35% | 37 | 5.5 | 857 | 9,777 | 73.3% | 36.4% | |
| 61.76% | 34 | 5.6 | 977 | 11,259 | 50.0% | 68.2% | |
| 58.82% | 34 | 5.6 | 872 | 11,366 | 90.9% | 43.5% | |
| 63.64% | 33 | 1.6 | 753 | 10,091 | 53.9% | 70.0% | |
| 54.55% | 33 | 5.3 | 828 | 11,623 | 66.7% | 50.0% | |
| 45.16% | 31 | 5.2 | 698 | 10,370 | 40.0% | 47.6% | |
| 46.43% | 28 | 5.5 | 960 | 10,965 | 46.1% | 46.7% | |
| 52.17% | 23 | 5.2 | 913 | 11,193 | 45.5% | 58.3% | |
| 47.83% | 23 | 5.2 | 868 | 10,056 | 55.6% | 42.9% | |
| 59.09% | 22 | 6.2 | 914 | 11,225 | 37.5% | 71.4% | |
| 40.91% | 22 | 5.8 | 976 | 10,852 | 36.4% | 45.5% | |
| 40.00% | 20 | 6.1 | 846 | 10,074 | 37.5% | 41.7% | |
| 42.11% | 19 | 5.6 | 950 | 11,189 | 57.1% | 33.3% | |
| 57.89% | 19 | 6.1 | 762 | 8,129 | 61.5% | 50.0% | |
| 42.11% | 19 | 4.8 | 1,021 | 10,754 | 25.0% | 54.5% | |
| 42.11% | 19 | 5.7 | 852 | 11,442 | 50.0% | 40.0% | |
| 55.56% | 18 | 5.9 | 1,135 | 12,422 | 66.7% | 50.0% | |
| 61.11% | 18 | 5.9 | 867 | 11,098 | 85.7% | 45.5% | |
| 37.50% | 16 | 3.6 | 787 | 10,044 | 16.7% | 50.0% | |
| 62.50% | 16 | 1.4 | 692 | 9,445 | 66.7% | 57.1% | |
| 56.25% | 16 | 3.5 | 843 | 9,979 | 85.7% | 33.3% | |
| 40.00% | 15 | 5.6 | 864 | 11,285 | 50.0% | 33.3% | |
| 60.00% | 15 | 6.3 | 1,038 | 10,104 | 57.1% | 62.5% | |
| 78.57% | 14 | 5.7 | 934 | 10,929 | 85.7% | 71.4% | |
| 57.14% | 14 | 5.6 | 858 | 9,978 | 42.9% | 71.4% | |
| 42.86% | 14 | 5.3 | 813 | 11,336 | 33.3% | 45.5% | |
| 69.23% | 13 | 5.1 | 1,020 | 10,448 | 66.7% | 71.4% | |
| 61.54% | 13 | 5.2 | 1,034 | 10,005 | 40.0% | 75.0% | |
| 41.67% | 12 | 1.6 | 698 | 9,563 | 50.0% | 37.5% | |
| 58.33% | 12 | 1.7 | 707 | 9,670 | 50.0% | 62.5% | |
| 66.67% | 12 | 5.3 | 757 | 9,708 | 66.7% | 66.7% | |
| 72.73% | 11 | 4.7 | 774 | 11,106 | 100.0% | 62.5% | |
| 18.18% | 11 | 5.5 | 827 | 8,730 | 28.6% | 0.0% | |
| 27.27% | 11 | 1.6 | 719 | 9,274 | 16.7% | 40.0% | |
| 36.36% | 11 | 2.6 | 713 | 10,903 | 25.0% | 42.9% | |
| 54.55% | 11 | 3.8 | 783 | 10,715 | 75.0% | 42.9% | |
| 30.00% | 10 | 2.7 | 821 | 10,819 | 100.0% | 22.2% | |
| 30.00% | 10 | 2.6 | 951 | 11,656 | 50.0% | 16.7% | |
| 30.00% | 10 | 1.6 | 522 | 7,423 | 33.3% | 25.0% | |
| 44.44% | 9 | 5.8 | 1,055 | 14,903 | 0.0% | 44.4% | |
| 22.22% | 9 | 2.0 | 719 | 10,615 | 25.0% | 20.0% | |
| 44.44% | 9 | 1.8 | 764 | 10,817 | 75.0% | 20.0% | |
| 50.00% | 8 | 5.0 | 1,074 | 10,633 | 33.3% | 60.0% | |
| 37.50% | 8 | 1.5 | 545 | 7,413 | 33.3% | 50.0% | |
| 75.00% | 8 | 1.9 | 782 | 10,185 | 33.3% | 100.0% | |
| 50.00% | 8 | 1.8 | 804 | 11,166 | 100.0% | 33.3% | |
| 57.14% | 7 | 2.4 | 936 | 9,884 | 50.0% | 66.7% | |
| 42.86% | 7 | 1.7 | 718 | 9,491 | 100.0% | 20.0% | |
| 71.43% | 7 | 6.3 | 872 | 10,367 | 75.0% | 66.7% | |
| 42.86% | 7 | 1.2 | 814 | 11,530 | 50.0% | 40.0% | |
| 57.14% | 7 | 1.6 | 684 | 9,604 | 33.3% | 75.0% | |
| 66.67% | 6 | 7.1 | 943 | 11,014 | 100.0% | 33.3% | |
| 50.00% | 6 | 3.4 | 779 | 12,856 | 100.0% | 40.0% | |
| 50.00% | 6 | 2.5 | 700 | 10,747 | 100.0% | 25.0% | |
| 80.00% | 5 | 2.7 | 775 | 10,968 | 50.0% | 100.0% | |
| 40.00% | 5 | 2.4 | 669 | 9,817 | 33.3% | 50.0% | |
| 40.00% | 5 | 1.3 | 747 | 10,508 | 50.0% | 33.3% | |
| 60.00% | 5 | 5.2 | 680 | 9,128 | 50.0% | 66.7% | |
| 60.00% | 5 | 5.7 | 905 | 9,720 | 33.3% | 100.0% | |
| 60.00% | 5 | 2.0 | 530 | 9,401 | 66.7% | 50.0% | |
| 60.00% | 5 | 6.4 | 855 | 8,852 | 66.7% | 50.0% | |
| 40.00% | 5 | 4.0 | 1,025 | 14,043 | 0.0% | 50.0% | |
| 20.00% | 5 | 5.3 | 768 | 12,108 | 0.0% | 25.0% | |
| 40.00% | 5 | 5.5 | 927 | 10,444 | 50.0% | 33.3% | |
| 60.00% | 5 | 5.6 | 917 | 13,371 | 100.0% | 50.0% | |
| 60.00% | 5 | 5.8 | 986 | 11,795 | 100.0% | 50.0% | |
| 80.00% | 5 | 3.9 | 915 | 13,836 | 100.0% | 75.0% | |
| 60.00% | 5 | 5.3 | 1,052 | 12,462 | 100.0% | 50.0% | |
| 40.00% | 5 | 1.6 | 654 | 12,330 | 0.0% | 40.0% | |
| 80.00% | 5 | 4.2 | 1,146 | 14,134 | 100.0% | 66.7% | |
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Zoe vs Lissandra - Frequently Asked Questions
How does Zoe do against Lissandra in League of Legends?
Lissandra wins the Zoe vs Lissandra matchup with a 57.1% win rate compared to Zoe's 42.9%, a 14.3 percentage point difference. This data is based on 14 recent ranked games in patch 26.14.
How does Zoe do against Lissandra in the early game?
In the early game, Lissandra has the advantage against Zoe with a 66.7% win rate versus 33.3%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Zoe do against Lissandra in the late game?
In the late game, Lissandra takes over the Zoe vs Lissandra matchup with a 54.5% win rate compared to 45.5%. Lissandra scales better into team fights and objective contests after 25 minutes.
Who wins the Zoe vs Lissandra matchup?
Lissandra wins the matchup against Zoe with a 57.1% win rate in League of Legends patch 26.14. The 14.3 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 14 games analyzed.
What is the best Zoe build against Lissandra?
The best Zoe build against Lissandra includes Luden's Echo, Shadowflame, Lich Bane with Crimson Lucidity. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Zoe runes against Lissandra?
The best Zoe runes against Lissandra use the Domination primary tree with Sorcery secondary. This rune setup achieves a 42.9% win rate in the Zoe vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.
Does Zoe counter Lissandra?
No, Zoe struggles against Lissandra with only a 42.9% win rate. Lissandra has the advantage in this matchup. Zoe players should focus on safe farming and avoiding extended trades to minimize Lissandra's lead.
How do I play Zoe against Lissandra?
When playing Zoe against Lissandra, play cautiously and avoid Lissandra's power spikes. Look for jungle assistance and team-dependent plays since Lissandra has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.
