
Zoevs Lissandra
Zoe vs Lissandra is a decisive matchup in LoL patch 26.11. Zoe wins with a 62.5% win rate (+25.0%) over Lissandra based on 24 games. Zoe holds the advantage in both the early and late game. Below you'll find the best Zoe build, runes, laning stats, and strategies for the Zoe vs Lissandra matchup.
Zoe Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Zoe performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Zoe vs Lissandra Matchup?

Zoe vs Lissandra Matchup Summary
The Zoe vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 24 recent matches analyzed, Zoe wins with a 62.5% win rate compared to Lissandra's 37.5%, giving Zoe a 25.0 percentage point advantage. Zoe dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Lissandra players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Lissandra leads by 190 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Zoe players can confidently pick into Lissandra and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Lissandra away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Zoe vs Lissandra Laning Phase Breakdown
Lissandra is favored during the laning phase against Zoe, winning 3 out of 5 key stat categories. Lissandra holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.
Best Zoe Build Against Lissandra
Spellslinger's Shoes is the optimal boots choice against Lissandra, providing the mobility and stats Zoe needs most in this matchup. The top-performing core items for Zoe against Lissandra are Luden's Echo, Shadowflame and Lich Bane. This combination gives Zoe an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 66.7% win rate across 3 games — well above average and making it the top item path against Lissandra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Zoe vs Lissandra matchup.
Early Game vs Late Game
Zoe dominates the early game (first 15 minutes) with a commanding 55.6% win rate — a 11.1 percentage point lead over Lissandra. This lopsided early game means Zoe can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Zoe is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Lissandra. Extended games heavily favor Zoe, whose kit and scaling make them a dominant force in team fights and objective control.
Zoe holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Lissandra players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Zoe Runes Against Lissandra
Running Domination primary with Sorcery secondary allows Zoe to press their advantage against Lissandra, amplifying the strengths that make this a favorable matchup.
Zoe matchup data for League of Legends patch 26.11. The table below shows Zoe's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zoe build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 52.32% | 151 | 5.8 | 914 | 11,000 | 53.4% | 51.3% | |
| 55.88% | 102 | 4.3 | 808 | 10,652 | 57.8% | 54.4% | |
| 46.88% | 96 | 5.8 | 812 | 11,276 | 34.3% | 54.1% | |
| 45.98% | 87 | 5.4 | 886 | 11,532 | 37.5% | 50.9% | |
| 55.70% | 79 | 4.6 | 875 | 11,439 | 53.9% | 56.6% | |
| 48.72% | 78 | 5.5 | 856 | 11,763 | 46.9% | 50.0% | |
| 45.95% | 74 | 5.7 | 944 | 11,280 | 55.6% | 40.4% | |
| 56.34% | 71 | 5.7 | 908 | 11,074 | 57.1% | 55.6% | |
| 52.17% | 69 | 5.8 | 866 | 11,221 | 58.1% | 47.4% | |
| 43.48% | 69 | 5.6 | 840 | 11,396 | 31.0% | 52.5% | |
| 48.39% | 62 | 5.3 | 903 | 10,346 | 48.3% | 48.5% | |
| 45.00% | 60 | 5.3 | 852 | 11,279 | 33.3% | 52.8% | |
| 49.12% | 57 | 5.9 | 876 | 10,855 | 55.6% | 43.3% | |
| 47.37% | 57 | 5.4 | 856 | 10,847 | 40.6% | 56.0% | |
| 48.94% | 47 | 1.9 | 683 | 9,593 | 52.4% | 46.1% | |
| 44.68% | 47 | 3.4 | 800 | 11,200 | 35.7% | 48.5% | |
| 66.67% | 45 | 5.6 | 913 | 11,254 | 72.2% | 63.0% | |
| 51.16% | 43 | 5.0 | 948 | 10,588 | 66.7% | 40.0% | |
| 57.50% | 40 | 5.5 | 928 | 11,930 | 47.1% | 65.2% | |
| 35.90% | 39 | 1.8 | 691 | 10,060 | 52.6% | 20.0% | |
| 53.85% | 39 | 5.9 | 916 | 11,369 | 35.0% | 73.7% | |
| 41.03% | 39 | 3.7 | 723 | 10,011 | 29.4% | 50.0% | |
| 57.89% | 38 | 1.4 | 763 | 9,419 | 57.9% | 57.9% | |
| 43.24% | 37 | 5.8 | 960 | 12,154 | 46.7% | 40.9% | |
| 48.65% | 37 | 5.6 | 881 | 12,105 | 54.5% | 46.1% | |
| 66.67% | 36 | 6.0 | 961 | 10,573 | 75.0% | 56.3% | |
| 38.89% | 36 | 5.8 | 904 | 12,573 | 33.3% | 40.7% | |
| 62.86% | 35 | 2.0 | 718 | 9,588 | 70.6% | 55.6% | |
| 35.29% | 34 | 3.9 | 744 | 9,787 | 33.3% | 36.4% | |
| 44.12% | 34 | 5.8 | 847 | 11,137 | 46.1% | 42.9% | |
| 61.76% | 34 | 5.3 | 871 | 10,955 | 60.0% | 63.2% | |
| 51.52% | 33 | 5.8 | 864 | 10,534 | 57.9% | 42.9% | |
| 29.03% | 31 | 6.0 | 895 | 11,404 | 40.0% | 23.8% | |
| 53.33% | 30 | 6.3 | 908 | 10,535 | 50.0% | 57.1% | |
| 60.00% | 30 | 1.7 | 808 | 10,674 | 62.5% | 59.1% | |
| 55.17% | 29 | 5.5 | 900 | 11,085 | 63.6% | 50.0% | |
| 42.86% | 28 | 6.2 | 1,000 | 11,159 | 57.1% | 28.6% | |
| 57.14% | 28 | 5.8 | 980 | 12,650 | 66.7% | 50.0% | |
| 53.85% | 26 | 5.5 | 893 | 10,895 | 45.5% | 60.0% | |
| 23.08% | 26 | 6.0 | 895 | 9,496 | 17.6% | 33.3% | |
| 38.46% | 26 | 1.6 | 620 | 9,901 | 45.5% | 33.3% | |
| 50.00% | 24 | 1.7 | 670 | 8,510 | 60.0% | 33.3% | |
| 45.83% | 24 | 2.1 | 733 | 10,974 | 44.4% | 46.7% | |
| 62.50% | 24 | 6.0 | 1,013 | 13,003 | 55.6% | 66.7% | |
| 54.17% | 24 | 5.6 | 894 | 11,316 | 66.7% | 46.7% | |
| 30.43% | 23 | 5.2 | 888 | 10,730 | 20.0% | 38.5% | |
| 57.14% | 21 | 2.5 | 669 | 8,228 | 63.6% | 50.0% | |
| 47.62% | 21 | 5.6 | 964 | 12,124 | 45.5% | 50.0% | |
| 47.62% | 21 | 3.7 | 847 | 10,744 | 66.7% | 40.0% | |
| 20.00% | 20 | 3.3 | 813 | 11,455 | 0.0% | 30.8% | |
| 60.00% | 20 | 5.0 | 740 | 10,260 | 77.8% | 45.5% | |
| 55.00% | 20 | 5.4 | 917 | 12,319 | 37.5% | 66.7% | |
| 42.11% | 19 | 1.6 | 467 | 8,450 | 44.4% | 40.0% | |
| 57.89% | 19 | 1.7 | 712 | 10,201 | 50.0% | 66.7% | |
| 27.78% | 18 | 1.6 | 718 | 9,765 | 11.1% | 44.4% | |
| 58.82% | 17 | 6.1 | 953 | 11,089 | 75.0% | 44.4% | |
| 35.29% | 17 | 2.1 | 701 | 10,094 | 75.0% | 23.1% | |
| 43.75% | 16 | 2.6 | 599 | 8,133 | 30.0% | 66.7% | |
| 43.75% | 16 | 4.1 | 743 | 11,535 | 50.0% | 41.7% | |
| 33.33% | 15 | 1.4 | 770 | 9,894 | 40.0% | 30.0% | |
| 73.33% | 15 | 5.0 | 1,064 | 12,031 | 80.0% | 70.0% | |
| 35.71% | 14 | 1.3 | 668 | 9,314 | 37.5% | 33.3% | |
| 46.15% | 13 | 5.9 | 926 | 9,921 | 62.5% | 20.0% | |
| 69.23% | 13 | 5.4 | 926 | 12,541 | 50.0% | 77.8% | |
| 61.54% | 13 | 1.5 | 639 | 9,849 | 100.0% | 37.5% | |
| 46.15% | 13 | 2.9 | 863 | 10,721 | 33.3% | 57.1% | |
| 46.15% | 13 | 1.5 | 564 | 10,056 | 33.3% | 57.1% | |
| 53.85% | 13 | 2.1 | 740 | 9,897 | 40.0% | 62.5% | |
| 41.67% | 12 | 1.5 | 739 | 9,091 | 75.0% | 25.0% | |
| 81.82% | 11 | 3.0 | 721 | 10,662 | 100.0% | 75.0% | |
| 40.00% | 10 | 4.7 | 863 | 10,329 | 0.0% | 57.1% | |
| 30.00% | 10 | 4.8 | 897 | 11,263 | 50.0% | 25.0% | |
| 50.00% | 10 | 5.5 | 1,056 | 13,063 | 0.0% | 55.6% | |
| 22.22% | 9 | 5.0 | 717 | 10,660 | 33.3% | 16.7% | |
| 50.00% | 8 | 6.0 | 873 | 12,319 | 0.0% | 66.7% | |
| 62.50% | 8 | 1.6 | 595 | 10,273 | 80.0% | 33.3% | |
| 57.14% | 7 | 5.9 | 744 | 12,407 | 66.7% | 50.0% | |
| 42.86% | 7 | 5.8 | 1,184 | 13,426 | 0.0% | 60.0% | |
| 57.14% | 7 | 4.8 | 723 | 11,311 | 66.7% | 50.0% | |
| 57.14% | 7 | 1.3 | 782 | 8,951 | 100.0% | 40.0% | |
| 57.14% | 7 | 1.3 | 616 | 9,110 | 50.0% | 66.7% | |
| 28.57% | 7 | 6.1 | 1,074 | 12,853 | 0.0% | 40.0% | |
| 33.33% | 6 | 5.7 | 731 | 9,432 | 66.7% | 0.0% | |
| 16.67% | 6 | 1.2 | 580 | 6,656 | 0.0% | 33.3% | |
| 16.67% | 6 | 4.5 | 911 | 8,722 | 33.3% | 0.0% | |
| 66.67% | 6 | 5.1 | 687 | 9,185 | 66.7% | 66.7% | |
| 50.00% | 6 | 5.7 | 855 | 9,616 | 33.3% | 66.7% | |
| 0.00% | 6 | 5.2 | 717 | 9,715 | 0.0% | 0.0% | |
| 60.00% | 5 | 4.7 | 996 | 8,758 | 66.7% | 50.0% | |
| 80.00% | 5 | 5.3 | 947 | 11,156 | 100.0% | 50.0% | |
| 20.00% | 5 | 5.7 | 810 | 11,570 | 0.0% | 33.3% | |
| 20.00% | 5 | 6.0 | 772 | 10,158 | 50.0% | 0.0% | |
| 40.00% | 5 | 5.2 | 870 | 12,014 | 0.0% | 66.7% | |
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Zoe vs Lissandra - Frequently Asked Questions
How does Zoe do against Lissandra in League of Legends?
Zoe wins the Zoe vs Lissandra matchup with a 62.5% win rate compared to Lissandra's 37.5%, a 25.0 percentage point difference. This data is based on 24 recent ranked games in patch 26.11.
How does Zoe do against Lissandra in the early game?
In the early game, Zoe has the advantage against Lissandra with a 55.6% win rate versus 44.4%. Zoe players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Zoe do against Lissandra in the late game?
In the late game, Zoe takes over the Zoe vs Lissandra matchup with a 66.7% win rate compared to 33.3%. Zoe scales better into team fights and objective contests after 25 minutes.
Who wins the Zoe vs Lissandra matchup?
Zoe wins the matchup against Lissandra with a 62.5% win rate in League of Legends patch 26.11. The 25.0 percentage point advantage means Zoe is significantly favored in this lane matchup based on 24 games analyzed.
What is the best Zoe build against Lissandra?
The best Zoe build against Lissandra includes Luden's Echo, Shadowflame, Lich Bane with Spellslinger's Shoes. This build achieves a 66.7% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Zoe runes against Lissandra?
The best Zoe runes against Lissandra use the Domination primary tree with Sorcery secondary. This rune setup achieves a 60.0% win rate in the Zoe vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.
Does Zoe counter Lissandra?
Yes, Zoe has a favorable matchup against Lissandra with a 62.5% win rate. Zoe strongly counters Lissandra in lane based on current patch 26.11 data.
How do I play Zoe against Lissandra?
When playing Zoe against Lissandra, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.
