Zoe - League of Legends Champion
Win Rate
50.4%
Pick Rate
1.9%

Zoevs Seraphine

BMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 20, 2026
MethodologyData Methodology

Zoe vs Seraphine is a decisive matchup in LoL patch 26.7. Zoe wins with a 80.0% win rate (+60.0%) over Seraphine based on 10 games. Zoe holds the advantage in both the early and late game. Below you'll find the best Zoe build, runes, laning stats, and strategies for the Zoe vs Seraphine matchup.

Zoe Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Zoe performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 80.0% win rateSeraphine(80.0%)
Zoe - 80.0% win rate in this matchup
Zoe
80.0% WR
VS
Seraphine vs Zoe matchup - 20.0% win rate
Seraphine
20.0% WR

Who Wins the Zoe vs Seraphine Matchup?

Zoe wins the Zoe vs Seraphine matchup
Winner
Zoe
Matches: 10
80.0%
Win Rate
20.0%
2.1
CS / min
1.9
819
DMG / min
444
11,386
Gold / game
9,657
138
Heal / min
297
305
DMG Mitigated / min
406
1.5
CC / min
1.2
100.0%
Early Game WR
0.0%
60.0%
Late Game WR
40.0%

Zoe vs Seraphine Matchup Summary

The Zoe vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 10 recent matches analyzed, Zoe wins with a 80.0% win rate compared to Seraphine's 20.0%, giving Zoe a 60.0 percentage point advantage. Zoe dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Seraphine players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in damage output, where Zoe leads by 376 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Zoe players can confidently pick into Seraphine and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Seraphine away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Zoe vs Seraphine Laning Phase Breakdown

Zoe wins the laning phase against Seraphine in League of Legends

Zoe is favored during the laning phase against Seraphine, winning 4 out of 5 key stat categories. Zoe holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
2.1Zoe
1.9Seraphine
Zoe and Seraphine farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
819Zoe
444Seraphine
Zoe heavily out-damages Seraphine by 376 DMG/min, dominating both short trades and all-in fights. Seraphine should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Zoe's sustained damage advantage take over.
Economy
11,386Zoe
9,657Seraphine
Zoe generates a commanding 1,729 more gold per game than Seraphine. This substantial economic advantage means Zoe consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Seraphine should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.5Zoe
1.2Seraphine
Zoe provides 0.3 seconds more crowd control per minute than Seraphine, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Zoe coordinate with their jungler and control the pace of skirmishes.
Sustain
442Zoe
704Seraphine
Seraphine vastly out-sustains Zoe, healing and mitigating 262 more damage per minute. This massive durability gap means Seraphine can absorb significant punishment and remain in lane while Zoe is forced to recall. Building grievous wounds early is essential for Zoe, and focusing on burst trade patterns rather than sustained fights is critical.

Best Zoe Build Against Seraphine

Sorcerer's Shoes is the optimal boots choice against Seraphine, providing the mobility and stats Zoe needs most in this matchup. The top-performing core items for Zoe against Seraphine are Luden's Echo, Stormsurge and Shurelya's Battlesong. This combination gives Zoe an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Zoe vs Seraphine matchup.

Early Game vs Late Game

Early Game
Zoe
100.0%
+100.0% advantage
Zoe early game win rateZoe100.0%
Seraphine early game win rateSeraphine0.0%
Late Game
Zoe
60.0%
+20.0% advantage
Zoe late game win rateZoe60.0%
Seraphine late game win rateSeraphine40.0%

Zoe dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Seraphine. This lopsided early game means Zoe can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Zoe is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Seraphine. Extended games heavily favor Zoe, whose kit and scaling make them a dominant force in team fights and objective control.

Zoe holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Seraphine players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Zoe Runes Against Seraphine

Domination rune tree - Zoe primary runes vs SeraphineDomination
Dark Harvest - best Zoe rune vs SeraphineSudden Impact - best Zoe rune vs SeraphineGrisly Mementos - best Zoe rune vs SeraphineTreasure Hunter - best Zoe rune vs Seraphine
Sorcery rune tree - Zoe secondary runes vs SeraphineSorcery
Absolute Focus - best Zoe rune vs SeraphineGathering Storm - best Zoe rune vs Seraphine
100.0% WR

Running Domination primary with Sorcery secondary allows Zoe to press their advantage against Seraphine, amplifying the strengths that make this a favorable matchup.


Zoe matchup data for League of Legends patch 26.7. The table below shows Zoe's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zoe build, runes, laning stats, and early vs late game analysis for that specific matchup.

Zoe matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
44.76%1056.088311,86338.0%50.9%
45.83%725.786211,52946.0%45.7%
45.31%646.279211,33034.4%56.3%
53.97%635.584810,58550.0%57.6%
63.46%525.892212,14360.0%65.6%
56.00%506.388711,56259.1%53.6%
40.00%505.281411,56237.5%41.2%
55.10%495.994511,50359.1%51.9%
42.55%474.379410,86318.8%54.8%
44.44%456.096511,85037.5%48.3%
60.00%405.992311,97271.4%53.9%
50.00%385.783311,63056.3%45.5%
51.35%376.290210,96842.1%61.1%
43.24%375.893611,49243.8%42.9%
50.00%345.898612,86545.5%52.2%
48.48%336.387410,32338.1%66.7%
51.52%335.889411,68861.1%40.0%
46.88%325.789811,12447.1%46.7%
50.00%325.989010,47652.6%46.1%
62.07%296.591811,99058.3%64.7%
62.07%296.294513,00463.6%61.1%
44.83%293.881310,72744.4%45.0%
30.77%265.486610,53055.6%17.6%
44.00%255.882010,45123.1%66.7%
36.00%256.295610,91050.0%26.7%
54.17%243.795310,32458.3%50.0%
45.83%245.588711,93350.0%43.8%
54.55%226.394512,25862.5%50.0%
54.55%226.187110,69455.6%53.9%
50.00%225.692711,85175.0%35.7%
42.86%215.691712,05950.0%40.0%
52.38%214.187311,83050.0%53.9%
52.38%216.297712,87266.7%46.7%
47.37%196.589812,10433.3%60.0%
31.58%191.37008,78730.0%33.3%
52.63%195.791611,86687.5%27.3%
50.00%182.181810,08855.6%44.4%
47.06%171.57149,35233.3%62.5%
41.18%171.48059,54157.1%30.0%
46.67%153.789412,48275.0%36.4%
57.14%146.787111,04454.5%66.7%
35.71%145.581710,95733.3%37.5%
69.23%137.01,08313,22075.0%60.0%
53.85%131.775310,60875.0%44.4%
61.54%131.67089,68383.3%42.9%
66.67%121.687111,22466.7%66.7%
75.00%124.890412,41675.0%75.0%
50.00%126.094311,92666.7%44.4%
41.67%126.28759,65525.0%75.0%
41.67%122.07199,62760.0%28.6%
63.64%111.67779,79783.3%40.0%
80.00%102.181911,386100.0%60.0%
60.00%105.786510,11550.0%75.0%
80.00%105.51,07211,159100.0%71.4%
55.56%92.784911,94750.0%57.1%
66.67%95.899612,035100.0%50.0%
55.56%91.37519,43860.0%50.0%
33.33%95.079512,25150.0%28.6%
66.67%91.68069,51080.0%50.0%
11.11%96.088910,03816.7%0.0%
62.50%81.57549,55150.0%100.0%
75.00%85.91,32513,267100.0%66.7%
37.50%81.777111,59933.3%40.0%
25.00%81.888610,68233.3%20.0%
50.00%81.475510,71025.0%75.0%
42.86%71.46266,35533.3%100.0%
42.86%75.191012,66375.0%0.0%
16.67%66.77199,85125.0%0.0%
50.00%65.81,00811,7100.0%100.0%
50.00%62.27239,85650.0%50.0%
100.00%66.879813,448100.0%100.0%
66.67%64.885310,36580.0%0.0%
100.00%51.663410,257100.0%100.0%
60.00%55.71,01412,48150.0%66.7%
20.00%56.26108,04420.0%0.0%
80.00%56.31,21111,720100.0%66.7%
60.00%55.689312,47266.7%50.0%
60.00%56.51,07013,251100.0%33.3%

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Zoe vs Seraphine - Frequently Asked Questions

How does Zoe do against Seraphine in League of Legends?

Zoe wins the Zoe vs Seraphine matchup with a 80.0% win rate compared to Seraphine's 20.0%, a 60.0 percentage point difference. This data is based on 10 recent ranked games in patch 26.7.

How does Zoe do against Seraphine in the early game?

In the early game, Zoe has the advantage against Seraphine with a 100.0% win rate versus 0.0%. Zoe players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Zoe do against Seraphine in the late game?

In the late game, Zoe takes over the Zoe vs Seraphine matchup with a 60.0% win rate compared to 40.0%. Zoe scales better into team fights and objective contests after 25 minutes.

Who wins the Zoe vs Seraphine matchup?

Zoe wins the matchup against Seraphine with a 80.0% win rate in League of Legends patch 26.7. The 60.0 percentage point advantage means Zoe is significantly favored in this lane matchup based on 10 games analyzed.

What is the best Zoe build against Seraphine?

The best Zoe build against Seraphine includes Luden's Echo, Stormsurge, Shurelya's Battlesong with Sorcerer's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Zoe runes against Seraphine?

The best Zoe runes against Seraphine use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Zoe vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Zoe counter Seraphine?

Yes, Zoe has a favorable matchup against Seraphine with a 80.0% win rate. Zoe strongly counters Seraphine in lane based on current patch 26.7 data.

How do I play Zoe against Seraphine?

When playing Zoe against Seraphine, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.