Zoe - League of Legends Champion
Win Rate
47.8%
Pick Rate
1.9%

Zoevs Seraphine

FMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 7, 2026
MethodologyData Methodology

Zoe vs Seraphine is a moderate matchup in LoL patch 26.11. Seraphine wins with a 51.1% win rate (+2.1%) over Zoe based on 47 games. Zoe wins the early laning phase while Seraphine scales better into the late game. Below you'll find the best Zoe build, runes, laning stats, and strategies for the Zoe vs Seraphine matchup.

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Zoe Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Zoe performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Zoe - 48.9% win rate in this matchup
Zoe
48.9% WR
VS
Seraphine vs Zoe matchup - 51.1% win rate
Seraphine
51.1% WR

Who Wins the Zoe vs Seraphine Matchup?

Seraphine wins the Zoe vs Seraphine matchup
Winner
Seraphine
Matches: 47
48.9%
Win Rate
51.1%
1.9
CS / min
2.0
683
DMG / min
462
9,593
Gold / game
9,108
92
Heal / min
298
300
DMG Mitigated / min
379
1.4
CC / min
1.0
52.4%
Early Game WR
47.6%
46.1%
Late Game WR
53.9%

Zoe vs Seraphine Matchup Summary

The Zoe vs Seraphine matchup is a very close matchup in League of Legends ranked play. Based on 47 recent matches analyzed, Seraphine wins with a 51.1% win rate compared to Zoe's 48.9%, giving Seraphine a 2.1 percentage point advantage. Game phase dynamics play a critical role here: Zoe controls the early laning stage, but Seraphine outscales as the game goes longer. The matchup shifts dramatically depending on game length — Zoe needs to press advantages before Seraphine reaches their power spikes, while Seraphine should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Seraphine leads by 284 HP/min — a difference that heavily influences the outcome of trades and skirmishes. While Seraphine is slightly favored, Zoe can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Seraphine's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Zoe vs Seraphine Laning Phase Breakdown

Zoe wins the laning phase against Seraphine in League of Legends

Zoe is favored during the laning phase against Seraphine, winning 3 out of 5 key stat categories. Zoe holds advantages in damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
1.9Zoe
2.0Seraphine
Zoe and Seraphine farm at nearly identical rates in this matchup, with only a 0.0 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
683Zoe
462Seraphine
Zoe heavily out-damages Seraphine by 220 DMG/min, dominating both short trades and all-in fights. Seraphine should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Zoe's sustained damage advantage take over.
Economy
9,593Zoe
9,108Seraphine
Zoe earns 485 more gold per game than Seraphine, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Zoe slightly faster item completions.
Utility
1.4Zoe
1.0Seraphine
Zoe provides 0.4 seconds more crowd control per minute than Seraphine, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Zoe coordinate with their jungler and control the pace of skirmishes.
Sustain
393Zoe
676Seraphine
Seraphine vastly out-sustains Zoe, healing and mitigating 284 more damage per minute. This massive durability gap means Seraphine can absorb significant punishment and remain in lane while Zoe is forced to recall. Building grievous wounds early is essential for Zoe, and focusing on burst trade patterns rather than sustained fights is critical.

Best Zoe Build Against Seraphine

Sorcerer's Shoes is the optimal boots choice against Seraphine, providing the mobility and stats Zoe needs most in this matchup. The top-performing core items for Zoe against Seraphine are Luden's Echo, Stormsurge and Shadowflame. This combination gives Zoe an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 75.0% win rate across 4 games — well above average and making it the top item path against Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Zoe vs Seraphine matchup.

Early Game vs Late Game

Early Game
Zoe
52.4%
+4.8% advantage
Zoe early game win rateZoe52.4%
Seraphine early game win rateSeraphine47.6%
Late Game
Seraphine
53.9%
+7.7% advantage
Zoe late game win rateZoe46.1%
Seraphine late game win rateSeraphine53.9%

During the early laning phase (first 15 minutes), Zoe has a meaningful 52.4% win rate, outperforming Seraphine by 4.8 percentage points. Zoe players should look to press this advantage through aggressive trades, wave priority, and early jungle coordination.

Seraphine is far superior in the late game (25+ minutes), boasting a 53.9% win rate — 7.7 points above Zoe. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Zoe must aggressively press their early advantage and close out the game before Seraphine reaches their scaling breakpoints. If Seraphine survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Zoe Runes Against Seraphine

Domination rune tree - Zoe primary runes vs SeraphineDomination
Electrocute - best Zoe rune vs SeraphineTaste of Blood - best Zoe rune vs SeraphineGrisly Mementos - best Zoe rune vs SeraphineTreasure Hunter - best Zoe rune vs Seraphine
Sorcery rune tree - Zoe secondary runes vs SeraphineSorcery
Manaflow Band - best Zoe rune vs SeraphineScorch - best Zoe rune vs Seraphine
55.6% WR

The Domination primary with Sorcery secondary combination helps Zoe maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Seraphine.


Zoe matchup data for League of Legends patch 26.11. The table below shows Zoe's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zoe build, runes, laning stats, and early vs late game analysis for that specific matchup.

Zoe matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
52.32%1515.891411,00053.4%51.3%
55.88%1024.380810,65257.8%54.4%
46.88%965.881211,27634.3%54.1%
45.98%875.488611,53237.5%50.9%
55.70%794.687511,43953.9%56.6%
48.72%785.585611,76346.9%50.0%
45.95%745.794411,28055.6%40.4%
56.34%715.790811,07457.1%55.6%
52.17%695.886611,22158.1%47.4%
43.48%695.684011,39631.0%52.5%
48.39%625.390310,34648.3%48.5%
45.00%605.385211,27933.3%52.8%
49.12%575.987610,85555.6%43.3%
47.37%575.485610,84740.6%56.0%
48.94%471.96839,59352.4%46.1%
44.68%473.480011,20035.7%48.5%
66.67%455.691311,25472.2%63.0%
51.16%435.094810,58866.7%40.0%
57.50%405.592811,93047.1%65.2%
35.90%391.869110,06052.6%20.0%
53.85%395.991611,36935.0%73.7%
41.03%393.772310,01129.4%50.0%
57.89%381.47639,41957.9%57.9%
43.24%375.896012,15446.7%40.9%
48.65%375.688112,10554.5%46.1%
66.67%366.096110,57375.0%56.3%
38.89%365.890412,57333.3%40.7%
62.86%352.07189,58870.6%55.6%
35.29%343.97449,78733.3%36.4%
44.12%345.884711,13746.1%42.9%
61.76%345.387110,95560.0%63.2%
51.52%335.886410,53457.9%42.9%
29.03%316.089511,40440.0%23.8%
53.33%306.390810,53550.0%57.1%
60.00%301.780810,67462.5%59.1%
55.17%295.590011,08563.6%50.0%
42.86%286.21,00011,15957.1%28.6%
57.14%285.898012,65066.7%50.0%
53.85%265.589310,89545.5%60.0%
23.08%266.08959,49617.6%33.3%
38.46%261.66209,90145.5%33.3%
50.00%241.76708,51060.0%33.3%
45.83%242.173310,97444.4%46.7%
62.50%246.01,01313,00355.6%66.7%
54.17%245.689411,31666.7%46.7%
30.43%235.288810,73020.0%38.5%
57.14%212.56698,22863.6%50.0%
47.62%215.696412,12445.5%50.0%
47.62%213.784710,74466.7%40.0%
20.00%203.381311,4550.0%30.8%
60.00%205.074010,26077.8%45.5%
55.00%205.491712,31937.5%66.7%
42.11%191.64678,45044.4%40.0%
57.89%191.771210,20150.0%66.7%
27.78%181.67189,76511.1%44.4%
58.82%176.195311,08975.0%44.4%
35.29%172.170110,09475.0%23.1%
43.75%162.65998,13330.0%66.7%
43.75%164.174311,53550.0%41.7%
33.33%151.47709,89440.0%30.0%
73.33%155.01,06412,03180.0%70.0%
35.71%141.36689,31437.5%33.3%
46.15%135.99269,92162.5%20.0%
69.23%135.492612,54150.0%77.8%
61.54%131.56399,849100.0%37.5%
46.15%132.986310,72133.3%57.1%
46.15%131.556410,05633.3%57.1%
53.85%132.17409,89740.0%62.5%
41.67%121.57399,09175.0%25.0%
81.82%113.072110,662100.0%75.0%
40.00%104.786310,3290.0%57.1%
30.00%104.889711,26350.0%25.0%
50.00%105.51,05613,0630.0%55.6%
22.22%95.071710,66033.3%16.7%
50.00%86.087312,3190.0%66.7%
62.50%81.659510,27380.0%33.3%
57.14%75.974412,40766.7%50.0%
42.86%75.81,18413,4260.0%60.0%
57.14%74.872311,31166.7%50.0%
57.14%71.37828,951100.0%40.0%
57.14%71.36169,11050.0%66.7%
28.57%76.11,07412,8530.0%40.0%
33.33%65.77319,43266.7%0.0%
16.67%61.25806,6560.0%33.3%
16.67%64.59118,72233.3%0.0%
66.67%65.16879,18566.7%66.7%
50.00%65.78559,61633.3%66.7%
0.00%65.27179,7150.0%0.0%
60.00%54.79968,75866.7%50.0%
80.00%55.394711,156100.0%50.0%
20.00%55.781011,5700.0%33.3%
20.00%56.077210,15850.0%0.0%
40.00%55.287012,0140.0%66.7%

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Zoe vs Seraphine - Frequently Asked Questions

How does Zoe do against Seraphine in League of Legends?

Seraphine wins the Zoe vs Seraphine matchup with a 51.1% win rate compared to Zoe's 48.9%, a 2.1 percentage point difference. This data is based on 47 recent ranked games in patch 26.11.

How does Zoe do against Seraphine in the early game?

In the early game, Zoe has the advantage against Seraphine with a 52.4% win rate versus 47.6%. Zoe players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Zoe do against Seraphine in the late game?

In the late game, Seraphine takes over the Zoe vs Seraphine matchup with a 53.9% win rate compared to 46.1%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Zoe vs Seraphine matchup?

Seraphine wins the matchup against Zoe with a 51.1% win rate in League of Legends patch 26.11. The 2.1 percentage point advantage means Seraphine is moderately favored in this lane matchup based on 47 games analyzed.

What is the best Zoe build against Seraphine?

The best Zoe build against Seraphine includes Luden's Echo, Stormsurge, Shadowflame with Sorcerer's Shoes. This build achieves a 75.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Zoe runes against Seraphine?

The best Zoe runes against Seraphine use the Domination primary tree with Sorcery secondary. This rune setup achieves a 55.6% win rate in the Zoe vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Zoe counter Seraphine?

No, Zoe struggles against Seraphine with only a 48.9% win rate. Seraphine has the advantage in this matchup. Zoe players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.

How do I play Zoe against Seraphine?

When playing Zoe against Seraphine, play cautiously and avoid Seraphine's power spikes. Look for jungle assistance and team-dependent plays since Seraphine has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.