Conflagration•Attack

Is Conflagration good in Slay the Spire 2?

In Slay the Spire 2, Conflagration is a rare attack from the Ironclad card pool. Its effect: Deal 8 damage to ALL enemies. Deals 2 additional damage for each other Attack you've played this turn. Right now it’s a premium pick that sits at B tier — one of the better cards you can add to a deck this run.

Over 52 tracked runs its win rate sits at 35.4%, 16.5% ahead of the 19.0% all-deck baseline. It sees niche play, included in only 1.4% of eligible runs. Within Ironclad runs it’s drafted 7.2% of the time, making it a regular part of that class’s decks. Decks that include it run about 1.1 copies on average.

Its standout pairing so far is Huddle Up, which lifts its win rate by +14.9% when the two share a deck. On the relic side, Reptile Trinket is its standout companion, worth a +20.7% win-rate swing alongside it. It costs 1 energy, gets upgraded 37.5% of the time, and tends to be picked up near floor 20.

Upgrading the card adds +1 CalculationBase, +1 ExtraDamage to its stat line. Of the runs that drafted it, 17 ended in victory against 31 deaths and 4 abandons. Its most common run-ender is Infested Prisms Elite, finishing 7.7% of the runs it shows up in. See the synergies, class split, and threats below for the full picture of where Conflagration fits a Ironclad deck.

Best Cards to Pair with Conflagration

Conflagration’s strongest card pairings so far are Huddle Up (+14.9%), Stoke (+14.9%), and Blood Wall (+14.8%), each shown with the win-rate lift it adds.

Huddle Up+14.9%3 runsStoke+14.9%5 runsBlood Wall+14.8%9 runsAshen Strike+14.8%9 runsInflame+12.5%12 runsJuggling+11.7%6 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Conflagration Win Rate by Class

Of the 2 classes that draft Conflagration, it performs best with Ironclad (36.2%) and Defect (0.0%).

The Ironclad36.2%51 runsThe Defect0.0%1 runs

Best Relics for Conflagration

The relics that swing Conflagration’s win rate the most are Reptile Trinket (+20.7%), Sparkling Rouge (+18.4%), and Lizard Tail (+18.0%), with each lift shown.

Reptile Trinket+20.7%7 runsSparkling Rouge+18.4%4 runsLizard Tail+18.0%6 runsPotion Belt+17.3%12 runsBag of Marbles+17.3%10 runsFresnel Lens+14.9%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Conflagration Card Details

A 1-energy rare attack, Conflagration is upgraded 37.5% of the time and tends to enter the deck around floor 20.

Deal 8 damage to ALL enemies. Deals 2 additional damage for each other Attack you've played this turn.

Upgrade: +1 CalculationBase, +1 ExtraDamage

What Ends Runs with Conflagration

Runs holding Conflagration end most often against Infested Prisms Elite (7.7%), Doormaker Boss (7.7%), and Queen Boss (7.7%) — the share of its runs each accounts for is shown.

• Infested Prisms Elite7.7% of runs
• Doormaker Boss7.7% of runs
• Queen Boss7.7% of runs
• Test Subject Boss7.7% of runs
• Knowledge Demon Boss3.8% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.