Slice•Attack

Is Slice good in Slay the Spire 2?

Slice is a common Silent attack in Slay the Spire 2. In combat it resolves as: Deal 6 damage. It currently underperforms most alternatives, sitting at D tier in our Slay the Spire 2 card rankings.

Across 129 recorded runs, decks running it win 22.9% of the time, comfortably clear of the 18.9% average, by 3.9%. It’s a more selective pick, turning up in just 3.4% of decks that could run it. Defect players keep it in 0.5% of their runs, so it’s a familiar sight in those decks. On average it shows up 1.4 times in the decks that take it.

It performs best next to Fan of Knives — together they post a +21.4% swing in win rate. It also has strong chemistry with the relic Snecko Skull, which moves its win rate by +25.9%. At 0 energy, it’s upgraded in 19.0% of runs and usually joins the deck around floor 12.

Upgraded, it gains +3 Damage, which is why so many decks invest a rest-site upgrade in it. That’s 27 wins, 91 deaths, and 11 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is Entomancer Elite, which closes out 6.2% of its appearances. Read on for Slice’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Silent run.

Best Cards to Pair with Slice

Ranked by win-rate lift, Slice performs best alongside Fan of Knives (+21.4%), Knife Trap (+20.7%), and Ultimate Defend (+19.0%).

Fan of Knives+21.4%12 runsKnife Trap+20.7%9 runsUltimate Defend+19.0%6 runsOmnislice+17.8%3 runsAll for One+17.8%3 runsAfterimage+15.8%14 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Slice Win Rate by Class

Slice is played across 4 classes, led by Defect (66.7%), Silent (22.1%), and Necrobinder (0.0%) by win rate.

The Defect66.7%3 runsThe Silent22.1%124 runsThe Necrobinder0.0%1 runsThe Regent0.0%1 runs

Best Relics for Slice

Slice pairs best with the relics Snecko Skull (+25.9%), Razor Tooth (+25.7%), and Gorget (+24.6%), ranked by win-rate lift.

Snecko Skull+25.9%7 runsRazor Tooth+25.7%6 runsGorget+24.6%20 runsLizard Tail+22.7%6 runsForgotten Soul+22.7%6 runsSignet Ring+22.0%4 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Slice Card Details

Slice is a common attack costing 0 energy; it’s upgraded in 19.0% of runs and usually picked up by floor 12.

Deal 6 damage.

Upgrade: +3 Damage

What Ends Runs with Slice

Slice’s most common run-enders are Entomancer Elite (6.2%), Kaiser Crab Boss (6.2%), and Queen Boss (5.4%).

• Entomancer Elite6.2% of runs
• Kaiser Crab Boss6.2% of runs
• Queen Boss5.4% of runs
• Knowledge Demon Boss5.4% of runs
• The Kin Boss4.7% of runs

See Also

Compare Slice with the rest of the best Slay the Spire 2 cards, relics, and classes below.