Snecko Skull•Relic

Is Snecko Skull good in Slay the Spire 2?

In Slay the Spire 2, Snecko Skull is a common relic you can pick up on your climb. Its effect: Whenever you apply Poison, apply an additional Poison. Performance-wise it’s a steady, unspectacular pick rated C tier overall.

Over 170 tracked runs the win rate of decks holding it sits at 45.6%, 31.6% ahead of the 14.0% all-run baseline. It sees lighter play, carried in only 1.5% of runs. It does its best work in the hands of the Silent, who post a 45.6% win rate with it. Within Silent runs specifically, it’s carried 5.9% of the time.

Its standout card pairing is Well-Laid Plans, which lifts the relic’s win rate by +31.7% when both are in play. It also works nicely with Knife Trap, good for a +25.9% win-rate change. It typically enters the deck near floor 24. As a common relic, how often it’s offered depends on its rarity tier.

Of the runs that carried it, 77 ended in victory while 92 fell to a defeat. Its most common run-ender is Test Subject Boss, finishing 6.5% of the runs it appears in. See the best cards, class split, and threats below for the full read on whether Snecko Skull is worth grabbing.

Pick or Skip: Snecko Skull

Players take Snecko Skull in 56.9% of the 304 offers it appears in; those runs win 45.9% against 37.6% for runs that passed, a pick lift of +7.9% over 172 decided runs.

Taken 173 times out of 304 offers.

Pick rate when offered counts offers, not runs: out of every time the game put this in front of a player, how often it was taken. It is not the same number as the share of runs that end up containing it.

Pick lift is the sample-adjusted gap between runs that took the option and runs that passed on it. It is the fair way to rank choices, because raw win rates put the smallest samples on top.

Best Cards with Snecko Skull

The cards that gain the most from carrying Snecko Skull are Well-Laid Plans (+31.7%), Knife Trap (+25.9%), and Burst (+25.9%), each shown with its win-rate swing.

Well-Laid Plans+31.7%23 runsKnife Trap+25.9%29 runsBurst+25.9%22 runsExpertise+23.2%16 runsBubble Bubble+22.3%28 runsTactician+21.1%33 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Snecko Skull Win Rate by Class

Snecko Skull’s class data comes mostly from the Silent, at a 45.6% win rate over 170 runs.

The Silentappears in 5.9% of its runs (170 tracked)

Snecko Skull Details

Carried in 1.5% of runs, Snecko Skull is a common relic typically acquired near floor 24.

Whenever you apply Poison, apply an additional Poison.

What Ends Runs with Snecko Skull

Runs carrying Snecko Skull end most often against Test Subject Boss (6.5%), Queen Boss (6.5%), and Kaiser Crab Boss (5.3%) — the share of its runs each accounts for is shown.

• Test Subject Boss6.5% of runs
• Queen Boss6.5% of runs
• Kaiser Crab Boss5.3% of runs
• The Insatiable Boss3.5% of runs
• Aeonglass Boss3.5% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.