
Alchemical CofferRelic
Upon pickup, gain potion slots filled with random potions.
Is Alchemical Coffer good in Slay the Spire 2?
In Slay the Spire 2, Alchemical Coffer is an ancient relic you can pick up on your climb. Its effect: Upon pickup, gain potion slots filled with random potions. The data marks it as a weaker relic, settling at D tier — rarely a run-defining grab.
Over 25 tracked runs the win rate of decks holding it sits at 36.4%, 17.4% ahead of the 18.9% all-run baseline. It sees lighter play, carried in only 0.7% of runs. It does its best work in the hands of the Regent, who post a 66.7% win rate with it. Within Regent runs specifically, it’s carried 0.9% of the time.
Its standout card pairing is CHARGE!!, which lifts the relic’s win rate by +63.6% when both are in play. It also works nicely with Refine Blade, good for a +63.6% win-rate change. It typically enters the deck near floor 18. As an ancient relic, how often it’s offered depends on its rarity tier.
Of the runs that carried it, 8 ended in victory while 14 fell to a defeat. Its most common run-ender is Knowledge Demon Boss, finishing 20.0% of the runs it appears in. See the best cards, class split, and threats below for the full read on whether Alchemical Coffer is worth grabbing.
Alchemical Coffer Win Rate & Pick Rate
At a 36.4% win rate, Alchemical Coffer runs 17.4% ahead of the 18.9% all-run baseline — the bars below put the two side by side.
Run Outcomes with Alchemical Coffer
Across the 25 runs that carried Alchemical Coffer, 8 ended in a win and 17 in a loss — a 32.0% win share, counting abandons as losses.
- Wins 32.0%
- Losses 68.0%
Best Cards with Alchemical Coffer
The cards that gain the most from carrying Alchemical Coffer are CHARGE!! (+63.6%), Refine Blade (+63.6%), and Debt (+63.6%), each shown with its win-rate swing.
Based on small co-occurring samples — treat these as early signals, not final verdicts.
Alchemical Coffer Details
Carried in 0.7% of runs, Alchemical Coffer is an ancient relic typically acquired near floor 18.
Upon pickup, gain potion slots filled with random potions.
What Ends Runs with Alchemical Coffer
Runs carrying Alchemical Coffer end most often against Knowledge Demon Boss (20.0%) and Queen Boss (8.0%) — the share of its runs each accounts for is shown.
- Knowledge Demon Boss20.0% of runs
- Queen Boss8.0% of runs
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Alchemical Coffer – Frequently Asked Questions
Is Alchemical Coffer good in Slay the Spire 2?
Across 25 tracked runs carrying it, Alchemical Coffer wins 36.4% of the time — +17.4% above the average run. Win rate reflects how often runs with the relic end in victory.
What does Alchemical Coffer do in Slay the Spire 2?
Upon pickup, gain potion slots filled with random potions.
How rare is Alchemical Coffer in Slay the Spire 2?
Alchemical Coffer is an Ancient relic, picked up in 0.7% of tracked runs.
What is the best card to use with Alchemical Coffer?
In tracked runs, Alchemical Coffer has performed best alongside CHARGE!!, which lifts its win rate by +63.6% over 3 runs together.
Which class is Alchemical Coffer best in?
Alchemical Coffer has its highest win rate with The Regent (66.7%).
See Also
Keep exploring Slay the Spire 2 tier lists and stats below.