Brimstone Relic

Is Brimstone good in Slay the Spire 2?

In Slay the Spire 2, Brimstone is a shop relic you can pick up on your climb. Its effect: At the start of your turn, gain Strength and ALL enemies gain Strength. The data marks it as a weaker relic, settling at D tier — rarely a run-defining grab.

Over 46 tracked runs the win rate of decks holding it sits at 45.6%, 31.8% ahead of the 13.8% all-run baseline. It sees lighter play, carried in only 0.2% of runs. It does its best work in the hands of the Ironclad, who post a 45.6% win rate with it. Within Ironclad runs specifically, it’s carried 1.0% of the time.

Its standout card pairing is Twin Strike, which lifts the relic’s win rate by +21.0% when both are in play. It also works nicely with Sword Boomerang, good for a +19.1% win-rate change. It typically enters the deck near floor 25. As a shop relic, how often it’s offered depends on its rarity tier.

Of the runs that carried it, 21 ended in victory while 25 fell to a defeat. Its most common run-ender is Test Subject Boss, finishing 10.9% of the runs it appears in. See the best cards, class split, and threats below for the full read on whether Brimstone is worth grabbing.

Pick or Skip: Brimstone

Players take Brimstone in 15.6% of the 295 offers it appears in; those runs win 45.6% against 21.3% for runs that passed, a pick lift of +20.0% over 46 decided runs.

Taken 46 times out of 295 offers.

Pick rate when offered counts offers, not runs: out of every time the game put this in front of a player, how often it was taken. It is not the same number as the share of runs that end up containing it.

Pick lift is the sample-adjusted gap between runs that took the option and runs that passed on it. It is the fair way to rank choices, because raw win rates put the smallest samples on top.

Best Cards with Brimstone

The cards that gain the most from carrying Brimstone are Twin Strike (+21.0%), Sword Boomerang (+19.1%), and Shrug It Off (+16.9%), each shown with its win-rate swing.

Twin Strike+21.0%21 runsSword Boomerang+19.1%17 runsShrug It Off+16.9%16 runsBreakthrough+16.9%16 runsThunderclap+15.5%18 runsExpect a Fight+14.3%15 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Brimstone Win Rate by Class

Brimstone’s class data comes mostly from the Ironclad, at a 45.6% win rate over 46 runs.

The Ironcladappears in 1.0% of its runs (46 tracked)

Brimstone Details

Carried in 0.2% of runs, Brimstone is a shop relic typically acquired near floor 25.

At the start of your turn, gain Strength and ALL enemies gain Strength.

What Ends Runs with Brimstone

Runs carrying Brimstone end most often against Test Subject Boss (10.9%), Decimillipede Elite (6.5%), and Kaiser Crab Boss (4.3%) — the share of its runs each accounts for is shown.

• Test Subject Boss10.9% of runs
• Decimillipede Elite6.5% of runs
• Kaiser Crab Boss4.3% of runs
• Queen Boss4.3% of runs
• Exoskeletons Normal4.3% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.