Anivia - League of Legends Champion
Win Rate
50.0%
Pick Rate
2.0%

Aniviavs Seraphine

CMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 4, 2026
MethodologyData Methodology

Anivia vs Seraphine is a very close matchup in LoL patch 26.11. Anivia wins with a 50.0% win rate (+0.0%) over Seraphine based on 40 games. Seraphine wins the early laning phase while Anivia scales better into the late game. Below you'll find the best Anivia build, runes, laning stats, and strategies for the Anivia vs Seraphine matchup.

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Anivia Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Anivia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Anivia - 50.0% win rate in this matchup
Anivia
50.0% WR
VS
Seraphine vs Anivia matchup - 50.0% win rate
Seraphine
50.0% WR

Who Wins the Anivia vs Seraphine Matchup?

Anivia wins the Anivia vs Seraphine matchup
Winner
Anivia
Matches: 40
50.0%
Win Rate
50.0%
2.6
CS / min
2.2
546
DMG / min
608
10,098
Gold / game
10,026
156
Heal / min
297
436
DMG Mitigated / min
390
1.6
CC / min
1.2
47.4%
Early Game WR
52.6%
52.4%
Late Game WR
47.6%

Anivia vs Seraphine Matchup Summary

The Anivia vs Seraphine matchup is essentially a coin-flip matchup in League of Legends ranked play. Based on 40 recent matches analyzed, Anivia wins with a 50.0% win rate compared to Seraphine's 50.0%, giving Anivia a 0.0 percentage point advantage. Game phase dynamics play a critical role here: Seraphine controls the early laning stage, but Anivia outscales as the game goes longer. The matchup shifts dramatically depending on game length — Seraphine needs to press advantages before Anivia reaches their power spikes, while Anivia should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Anivia leads by 0.4s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Anivia has a statistical edge, but the margin is close enough that respecting Seraphine's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Anivia vs Seraphine Laning Phase Breakdown

Anivia wins the laning phase against Seraphine in League of Legends

Anivia is favored during the laning phase against Seraphine, winning 3 out of 5 key stat categories. Anivia holds advantages in farming, gold income and crowd control, making them the stronger laner in this matchup.

Farming
2.6Anivia
2.2Seraphine
Anivia edges out Seraphine by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 6 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Anivia.
Damage
546Anivia
608Seraphine
Seraphine deals 62 more champion damage per minute than Anivia. While noticeable in extended trades, this gap can be offset by Anivia choosing favorable fight windows, such as engaging when Seraphine's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
10,098Anivia
10,026Seraphine
Anivia and Seraphine generate nearly equal gold per game, with just a 72 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
1.6Anivia
1.2Seraphine
Anivia provides 0.4 seconds more crowd control per minute than Seraphine, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Anivia coordinate with their jungler and control the pace of skirmishes.
Sustain
592Anivia
687Seraphine
Seraphine heals and mitigates 96 more damage per minute than Anivia, providing moderate extra durability. This sustain edge allows Seraphine to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Anivia.

Best Anivia Build Against Seraphine

Sorcerer's Shoes is the optimal boots choice against Seraphine, providing the mobility and stats Anivia needs most in this matchup. The top-performing core items for Anivia against Seraphine are Rod of Ages, Zhonya's Hourglass and Malignance. This combination gives Anivia an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Anivia vs Seraphine matchup.

Early Game vs Late Game

Early Game
Seraphine
52.6%
+5.3% advantage
Anivia early game win rateAnivia47.4%
Seraphine early game win rateSeraphine52.6%
Late Game
Anivia
52.4%
+4.8% advantage
Anivia late game win rateAnivia52.4%
Seraphine late game win rateSeraphine47.6%

Seraphine dominates the early game (first 15 minutes) with a commanding 52.6% win rate — a 5.3 percentage point lead over Anivia. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

In the late game (25+ minutes), Anivia takes over with a 52.4% win rate, leading Seraphine by 4.8 percentage points. Anivia scales more effectively into team fights and objective contests.

This matchup features a dramatic power shift: Seraphine must aggressively press their early advantage and close out the game before Anivia reaches their scaling breakpoints. If Anivia survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Anivia Runes Against Seraphine

Sorcery rune tree - Anivia primary runes vs SeraphineSorcery
Arcane Comet - best Anivia rune vs SeraphineManaflow Band - best Anivia rune vs SeraphineTranscendence - best Anivia rune vs SeraphineScorch - best Anivia rune vs Seraphine
Precision rune tree - Anivia secondary runes vs SeraphinePrecision
Coup de Grace - best Anivia rune vs SeraphinePresence of Mind - best Anivia rune vs Seraphine
60.0% WR

The Sorcery primary with Precision secondary combination helps Anivia maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Seraphine.


Anivia matchup data for League of Legends patch 26.11. The table below shows Anivia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Anivia build, runes, laning stats, and early vs late game analysis for that specific matchup.

Anivia matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
52.88%1046.971411,69144.0%61.1%
52.81%896.778510,93155.8%48.6%
42.05%886.774011,12647.4%38.0%
47.67%865.265810,92533.3%58.0%
44.05%846.479911,26241.7%45.8%
52.17%696.869510,94858.1%47.4%
53.62%696.772411,66353.3%53.9%
38.71%626.485011,89147.8%33.3%
43.55%626.068710,82543.8%43.3%
44.26%616.672611,46340.0%47.2%
46.55%586.471910,85942.3%50.0%
49.09%556.267710,15451.4%45.0%
55.10%496.370911,61352.6%56.7%
50.00%486.264510,97842.1%55.2%
60.42%486.770912,00353.9%62.9%
68.18%446.086910,83873.9%61.9%
53.49%436.573111,46243.8%59.3%
39.02%416.874912,14042.9%37.0%
52.50%406.777212,00658.8%47.8%
50.00%402.654610,09847.4%52.4%
48.65%375.977311,31441.7%52.0%
47.22%366.787111,73656.3%40.0%
61.11%364.868711,97158.3%62.5%
38.24%341.95458,83236.4%41.7%
38.24%343.363310,98241.7%36.4%
45.45%335.970910,68550.0%42.9%
51.52%336.275810,94450.0%52.9%
50.00%326.379710,53760.0%41.2%
53.13%326.482810,73550.0%56.3%
41.94%314.081910,78738.5%44.4%
41.94%316.878212,06446.1%38.9%
38.71%316.67619,64735.3%42.9%
46.67%302.16249,30545.5%47.4%
44.83%297.072710,78335.7%53.3%
44.83%295.764010,80036.4%50.0%
46.43%286.676712,35066.7%36.8%
35.71%286.369410,36633.3%38.5%
42.31%262.55789,38636.4%46.7%
46.15%266.67039,61642.9%50.0%
56.00%256.57499,37956.3%55.6%
41.67%242.460510,00537.5%43.8%
58.33%246.771311,38933.3%73.3%
54.17%245.46138,48457.1%50.0%
50.00%246.176811,50263.6%38.5%
62.50%247.36959,81664.3%60.0%
41.67%246.565610,52830.8%54.5%
39.13%236.583912,71425.0%42.1%
50.00%226.269211,49328.6%60.0%
31.82%225.368810,29122.2%38.5%
38.10%212.15637,85328.6%57.1%
61.90%216.386710,86444.4%75.0%
30.00%206.16979,34937.5%25.0%
75.00%207.076210,60790.0%60.0%
55.00%207.170611,28160.0%50.0%
60.00%206.175811,19466.7%54.5%
36.84%196.879610,68328.6%41.7%
57.89%196.877811,67255.6%60.0%
61.11%186.384412,58633.3%75.0%
35.29%174.087811,30650.0%27.3%
23.53%176.972712,39412.5%33.3%
43.75%167.57199,02641.7%50.0%
50.00%166.289310,01260.0%45.5%
62.50%166.874211,72060.0%63.6%
31.25%167.078412,22628.6%33.3%
26.67%152.852410,3090.0%36.4%
60.00%152.246010,33342.9%75.0%
73.33%151.95479,23055.6%100.0%
53.33%156.783311,37850.0%57.1%
66.67%156.595211,02166.7%66.7%
40.00%156.674011,87520.0%50.0%
64.29%147.478011,12555.6%80.0%
35.71%146.374510,28557.1%14.3%
57.14%141.96108,78760.0%55.6%
28.57%147.277911,06028.6%28.6%
38.46%132.04899,70033.3%42.9%
61.54%136.61,06910,68842.9%83.3%
46.15%131.95278,75650.0%42.9%
46.15%136.584611,98580.0%25.0%
38.46%131.74598,57433.3%42.9%
61.54%132.15319,81762.5%60.0%
53.85%136.979812,12650.0%55.6%
58.33%127.085211,01571.4%40.0%
27.27%116.689811,49950.0%22.2%
40.00%106.675212,88266.7%28.6%
50.00%105.672213,026100.0%37.5%
30.00%103.14569,9990.0%60.0%
70.00%101.64557,65366.7%75.0%
60.00%105.582813,202100.0%55.6%
40.00%106.872912,28350.0%37.5%
40.00%105.471310,84833.3%50.0%
55.56%94.071712,35333.3%66.7%
44.44%96.275110,02266.7%33.3%
33.33%95.576713,0980.0%37.5%
55.56%96.079411,629100.0%42.9%
88.89%96.772912,355100.0%75.0%
25.00%86.379611,15425.0%25.0%
50.00%86.274411,58150.0%50.0%
87.50%86.967912,488100.0%83.3%
62.50%82.05498,28880.0%33.3%
62.50%86.465810,97566.7%60.0%
37.50%84.74577,57040.0%33.3%
25.00%81.75539,25020.0%33.3%
37.50%85.258610,29225.0%50.0%
42.86%76.463610,67075.0%0.0%
71.43%76.966510,57850.0%100.0%
14.29%72.65748,96520.0%0.0%
71.43%76.58519,21750.0%100.0%
42.86%76.067310,37633.3%50.0%
28.57%76.674212,5870.0%40.0%
83.33%67.370510,68575.0%100.0%
50.00%62.36308,70450.0%50.0%
33.33%66.77168,39250.0%0.0%
16.67%67.074611,60133.3%0.0%
50.00%65.56898,26640.0%100.0%
80.00%56.364912,607100.0%75.0%
20.00%56.04778,04250.0%0.0%
40.00%53.668110,2360.0%66.7%
80.00%54.16588,54080.0%0.0%
40.00%56.95839,08350.0%33.3%
60.00%56.073814,7160.0%60.0%
80.00%51.858511,8900.0%80.0%
60.00%55.467111,7600.0%75.0%

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Anivia vs Seraphine - Frequently Asked Questions

How does Anivia do against Seraphine in League of Legends?

Anivia wins the Anivia vs Seraphine matchup with a 50.0% win rate compared to Seraphine's 50.0%, a 0.0 percentage point difference. This data is based on 40 recent ranked games in patch 26.11.

How does Anivia do against Seraphine in the early game?

In the early game, Seraphine has the advantage against Anivia with a 52.6% win rate versus 47.4%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Anivia do against Seraphine in the late game?

In the late game, Anivia takes over the Anivia vs Seraphine matchup with a 52.4% win rate compared to 47.6%. Anivia scales better into team fights and objective contests after 25 minutes.

Who wins the Anivia vs Seraphine matchup?

Anivia wins the matchup against Seraphine with a 50.0% win rate in League of Legends patch 26.11. The 0.0 percentage point advantage means Anivia is slightly favored in this lane matchup based on 40 games analyzed.

What is the best Anivia build against Seraphine?

The best Anivia build against Seraphine includes Rod of Ages, Zhonya's Hourglass, Malignance with Sorcerer's Shoes. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Anivia runes against Seraphine?

The best Anivia runes against Seraphine use the Sorcery primary tree with Precision secondary. This rune setup achieves a 60.0% win rate in the Anivia vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Anivia counter Seraphine?

Yes, Anivia has a favorable matchup against Seraphine with a 50.0% win rate. Anivia slightly edges out Seraphine in lane based on current patch 26.11 data.

How do I play Anivia against Seraphine?

When playing Anivia against Seraphine, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Seraphine. Build the recommended items and runes for this specific matchup for the best results.