Seraphine - League of Legends Champion
Win Rate
52.3%
Pick Rate
7.8%

Seraphinevs Anivia

SSupportMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 5, 2026
MethodologyData Methodology

Seraphine vs Anivia is a very close matchup in LoL patch 26.11. Seraphine wins with a 50.0% win rate (+0.0%) over Anivia based on 40 games. Seraphine wins the early laning phase while Anivia scales better into the late game. Below you'll find the best Seraphine build, runes, laning stats, and strategies for the Seraphine vs Anivia matchup.

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Seraphine Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Seraphine performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 50.0% win rate in this matchup
Seraphine
50.0% WR
VS
Anivia vs Seraphine matchup - 50.0% win rate
Anivia
50.0% WR

Who Wins the Seraphine vs Anivia Matchup?

Seraphine wins the Seraphine vs Anivia matchup
Winner
Seraphine
Matches: 40
50.0%
Win Rate
50.0%
2.2
CS / min
2.6
608
DMG / min
546
10,026
Gold / game
10,098
297
Heal / min
156
390
DMG Mitigated / min
436
1.2
CC / min
1.6
52.6%
Early Game WR
47.4%
47.6%
Late Game WR
52.4%

Seraphine vs Anivia Matchup Summary

The Seraphine vs Anivia matchup is essentially a coin-flip matchup in League of Legends ranked play. Based on 40 recent matches analyzed, Seraphine wins with a 50.0% win rate compared to Anivia's 50.0%, giving Seraphine a 0.0 percentage point advantage. Game phase dynamics play a critical role here: Seraphine controls the early laning stage, but Anivia outscales as the game goes longer. The matchup shifts dramatically depending on game length — Seraphine needs to press advantages before Anivia reaches their power spikes, while Anivia should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Anivia leads by 0.4s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine has a statistical edge, but the margin is close enough that respecting Anivia's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Seraphine vs Anivia Laning Phase Breakdown

Anivia wins the laning phase against Seraphine in League of Legends

Anivia is favored during the laning phase against Seraphine, winning 3 out of 5 key stat categories. Anivia holds advantages in farming, gold income and crowd control, making them the stronger laner in this matchup.

Farming
2.2Seraphine
2.6Anivia
Anivia edges out Seraphine by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 6 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Anivia.
Damage
608Seraphine
546Anivia
Seraphine deals 62 more champion damage per minute than Anivia. While noticeable in extended trades, this gap can be offset by Anivia choosing favorable fight windows, such as engaging when Seraphine's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
10,026Seraphine
10,098Anivia
Seraphine and Anivia generate nearly equal gold per game, with just a 72 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
1.2Seraphine
1.6Anivia
Anivia provides 0.4 seconds more crowd control per minute than Seraphine, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Anivia coordinate with their jungler and control the pace of skirmishes.
Sustain
687Seraphine
592Anivia
Seraphine heals and mitigates 96 more damage per minute than Anivia, providing moderate extra durability. This sustain edge allows Seraphine to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Anivia.

Best Seraphine Build Against Anivia

Ionian Boots of Lucidity is the optimal boots choice against Anivia, providing the mobility and stats Seraphine needs most in this matchup. The top-performing core items for Seraphine against Anivia are Echoes of Helia, Rylai's Crystal Scepter and Diadem of Songs. This combination gives Seraphine an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 66.7% win rate across 3 games — well above average and making it the top item path against Anivia. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Seraphine vs Anivia matchup.

Early Game vs Late Game

Early Game
Seraphine
52.6%
+5.3% advantage
Seraphine early game win rateSeraphine52.6%
Anivia early game win rateAnivia47.4%
Late Game
Anivia
52.4%
+4.8% advantage
Seraphine late game win rateSeraphine47.6%
Anivia late game win rateAnivia52.4%

Seraphine dominates the early game (first 15 minutes) with a commanding 52.6% win rate — a 5.3 percentage point lead over Anivia. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

In the late game (25+ minutes), Anivia takes over with a 52.4% win rate, leading Seraphine by 4.8 percentage points. Anivia scales more effectively into team fights and objective contests.

This matchup features a dramatic power shift: Seraphine must aggressively press their early advantage and close out the game before Anivia reaches their scaling breakpoints. If Anivia survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Seraphine Runes Against Anivia

Sorcery rune tree - Seraphine primary runes vs AniviaSorcery
Summon Aery - best Seraphine rune vs AniviaManaflow Band - best Seraphine rune vs AniviaTranscendence - best Seraphine rune vs AniviaGathering Storm - best Seraphine rune vs Anivia
Resolve rune tree - Seraphine secondary runes vs AniviaResolve
Font of Life - best Seraphine rune vs AniviaRevitalize - best Seraphine rune vs Anivia
47.4% WR

The Sorcery primary with Resolve secondary combination helps Seraphine maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Anivia.


Seraphine matchup data for League of Legends patch 26.11. The table below shows Seraphine's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Seraphine build, runes, laning stats, and early vs late game analysis for that specific matchup.

Seraphine matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.75%7791.74669,35944.9%49.5%
50.91%5501.44939,17358.0%45.0%
49.45%5481.44879,00751.2%48.0%
50.83%5431.44879,19746.8%53.9%
52.69%5011.54979,35248.8%55.5%
50.21%4781.85269,25551.6%49.0%
48.69%4211.54709,01249.2%48.3%
50.00%3341.44539,01050.4%49.7%
50.91%3301.95249,71553.4%49.2%
51.72%3191.44699,56046.7%55.4%
52.44%3071.44938,93052.7%52.2%
53.17%2841.74839,53147.7%56.6%
52.84%2821.44878,90149.2%55.8%
50.78%2581.54449,24750.5%51.0%
47.97%2461.54669,32744.7%50.4%
54.85%2371.85849,76454.8%54.9%
54.85%2371.44528,96551.9%57.4%
53.07%2281.53918,66358.8%46.8%
54.63%2271.84989,66455.6%54.0%
43.13%2111.35028,90135.6%48.8%
52.22%2031.45229,03758.4%47.4%
43.22%1991.54988,96147.1%40.4%
48.44%1921.44979,41851.2%46.3%
53.45%1741.84629,23249.4%56.7%
49.70%1691.66149,70344.4%52.2%
52.26%1551.44799,11856.9%48.2%
57.53%1461.45699,69067.9%51.1%
54.48%1454.566211,52162.3%50.0%
52.52%1391.44899,05164.1%42.7%
61.29%1241.64819,07567.7%54.8%
50.00%1221.44628,51250.8%49.1%
50.00%1201.45089,23252.8%47.8%
51.30%1151.44638,90542.2%57.1%
59.13%1156.281412,23054.7%62.9%
53.49%861.54809,03567.5%41.3%
54.88%825.867711,89860.0%51.9%
61.25%804.878912,00275.9%52.9%
56.76%746.880712,47863.9%50.0%
53.42%732.05109,99152.0%54.2%
56.16%731.55149,44956.8%55.6%
46.88%641.54679,51052.0%43.6%
43.33%601.65579,12160.7%28.1%
48.33%602.14408,59548.3%48.4%
54.24%596.283112,84042.1%60.0%
54.24%593.359210,05860.9%50.0%
60.34%585.375111,90651.9%67.7%
63.16%572.056710,73279.0%55.3%
44.23%521.75759,42052.0%37.0%
51.06%472.04629,10847.6%53.9%
50.00%402.260810,02652.6%47.6%
56.76%376.389112,39562.5%52.4%
44.44%362.55159,08730.8%52.2%
60.61%334.259811,53455.6%62.5%
51.52%335.366611,60061.5%45.0%
42.42%336.281310,73542.1%42.9%
51.52%336.878711,42658.8%43.8%
65.63%321.64749,16373.3%58.8%
65.63%324.168110,15666.7%64.7%
58.06%311.64859,79966.7%52.6%
56.67%306.673310,93362.5%50.0%
41.38%291.45019,36630.8%50.0%
44.44%275.167710,72263.6%31.3%
62.96%271.649810,32862.5%63.2%
54.17%244.26249,65645.5%61.5%
50.00%222.45679,74940.0%58.3%
45.45%223.04909,41825.0%57.1%
63.64%222.250811,56760.0%64.7%
40.00%206.580113,55633.3%41.2%
55.00%206.779212,47966.7%45.5%
55.00%202.04629,45857.1%53.9%
45.00%205.871411,07240.0%50.0%
70.00%201.464510,69887.5%58.3%
63.16%191.443410,16060.0%64.3%
61.11%185.67038,05964.3%50.0%
58.82%176.286512,02650.0%63.6%
35.29%171.244610,23775.0%23.1%
75.00%166.791813,62771.4%77.8%
37.50%161.54798,92840.0%36.4%
60.00%156.776112,98866.7%55.6%
40.00%155.359710,54633.3%44.4%
60.00%151.646310,50775.0%54.5%
50.00%143.264710,32850.0%50.0%
50.00%142.65519,74250.0%50.0%
42.86%144.85849,77450.0%37.5%
53.85%136.392112,20066.7%42.9%
30.77%134.16039,87733.3%28.6%
61.54%133.15949,46842.9%83.3%
58.33%126.78259,19670.0%0.0%
50.00%124.36669,42433.3%66.7%
58.33%126.076411,19160.0%57.1%
72.73%116.175811,907100.0%66.7%
27.27%114.55499,3630.0%50.0%
54.55%116.266011,06050.0%60.0%
60.00%105.680311,24250.0%75.0%
80.00%101.44777,16187.5%50.0%
66.67%94.552110,244100.0%62.5%
44.44%91.84238,69366.7%33.3%
37.50%86.293011,95740.0%33.3%
62.50%81.66239,74233.3%80.0%
37.50%81.53958,01025.0%50.0%
37.50%81.34679,59625.0%50.0%
25.00%85.367010,06850.0%16.7%
25.00%83.45779,67325.0%25.0%
62.50%81.457011,7740.0%71.4%
75.00%85.470711,28850.0%83.3%
50.00%81.14638,69050.0%50.0%
50.00%86.298713,25366.7%40.0%
75.00%81.648710,73550.0%83.3%
85.71%71.45378,417100.0%0.0%
42.86%71.949210,03133.3%50.0%
71.43%73.163510,657100.0%60.0%
57.14%73.473912,184100.0%50.0%
100.00%73.15957,466100.0%100.0%
71.43%73.05208,01175.0%66.7%
33.33%67.382210,97625.0%50.0%
100.00%62.35489,903100.0%100.0%
83.33%62.247410,918100.0%80.0%
50.00%61.63829,86350.0%50.0%
100.00%55.957011,5490.0%100.0%
40.00%51.649610,44750.0%33.3%
60.00%51.256510,3000.0%75.0%
40.00%56.06469,77425.0%100.0%
40.00%53.864610,54966.7%0.0%
80.00%51.549910,15550.0%100.0%

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Seraphine vs Anivia - Frequently Asked Questions

How does Seraphine do against Anivia in League of Legends?

Seraphine wins the Seraphine vs Anivia matchup with a 50.0% win rate compared to Anivia's 50.0%, a 0.0 percentage point difference. This data is based on 40 recent ranked games in patch 26.11.

How does Seraphine do against Anivia in the early game?

In the early game, Seraphine has the advantage against Anivia with a 52.6% win rate versus 47.4%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Seraphine do against Anivia in the late game?

In the late game, Anivia takes over the Seraphine vs Anivia matchup with a 52.4% win rate compared to 47.6%. Anivia scales better into team fights and objective contests after 25 minutes.

Who wins the Seraphine vs Anivia matchup?

Seraphine wins the matchup against Anivia with a 50.0% win rate in League of Legends patch 26.11. The 0.0 percentage point advantage means Seraphine is slightly favored in this lane matchup based on 40 games analyzed.

What is the best Seraphine build against Anivia?

The best Seraphine build against Anivia includes Echoes of Helia, Rylai's Crystal Scepter, Diadem of Songs with Ionian Boots of Lucidity. This build achieves a 66.7% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Seraphine runes against Anivia?

The best Seraphine runes against Anivia use the Sorcery primary tree with Resolve secondary. This rune setup achieves a 47.4% win rate in the Seraphine vs Anivia matchup. See the full rune breakdown in the matchup comparison above.

Does Seraphine counter Anivia?

Yes, Seraphine has a favorable matchup against Anivia with a 50.0% win rate. Seraphine slightly edges out Anivia in lane based on current patch 26.11 data.

How do I play Seraphine against Anivia?

When playing Seraphine against Anivia, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.