Cassiopeia - League of Legends Champion
Win Rate
48.3%
Pick Rate
0.9%

Cassiopeiavs Nasus

FMage
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Cassiopeia vs Nasus is a decisive matchup in LoL patch 26.14. Cassiopeia wins with a 85.7% win rate (+71.4%) over Nasus based on 7 games. Cassiopeia holds the advantage in both the early and late game. Below you'll find the best Cassiopeia build, runes, laning stats, and strategies for the Cassiopeia vs Nasus matchup.

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Cassiopeia Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Cassiopeia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Cassiopeia - 85.7% win rate in this matchup
Cassiopeia
85.7% WR
VS
Nasus vs Cassiopeia matchup - 14.3% win rate
Nasus
14.3% WR

Who Wins the Cassiopeia vs Nasus Matchup?

Cassiopeia wins the Cassiopeia vs Nasus matchup
Winner
Cassiopeia
Matches: 7
85.7%
Win Rate
14.3%
6.8
CS / min
6.3
1,021
DMG / min
532
12,042
Gold / game
10,148
266
Heal / min
402
557
DMG Mitigated / min
1,429
1.2
CC / min
0.6
100.0%
Early Game WR
0.0%
66.7%
Late Game WR
33.3%

Cassiopeia vs Nasus Matchup Summary

The Cassiopeia vs Nasus matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Cassiopeia wins with a 85.7% win rate compared to Nasus's 14.3%, giving Cassiopeia a 71.4 percentage point advantage. Cassiopeia dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Nasus players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Nasus leads by 1,008 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Cassiopeia players can confidently pick into Nasus and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Nasus away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Cassiopeia vs Nasus Laning Phase Breakdown

Cassiopeia wins the laning phase against Nasus in League of Legends

Cassiopeia is favored during the laning phase against Nasus, winning 4 out of 5 key stat categories. Cassiopeia holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
6.8Cassiopeia
6.3Nasus
Cassiopeia edges out Nasus by 0.6 CS per minute — a moderate farming advantage that adds up to roughly 9 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Cassiopeia.
Damage
1,021Cassiopeia
532Nasus
Cassiopeia heavily out-damages Nasus by 488 DMG/min, dominating both short trades and all-in fights. Nasus should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Cassiopeia's sustained damage advantage take over.
Economy
12,042Cassiopeia
10,148Nasus
Cassiopeia generates a commanding 1,893 more gold per game than Nasus. This substantial economic advantage means Cassiopeia consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Nasus should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.2Cassiopeia
0.6Nasus
Cassiopeia provides 0.6 seconds more crowd control per minute than Nasus, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Cassiopeia coordinate with their jungler and control the pace of skirmishes.
Sustain
823Cassiopeia
1,831Nasus
Nasus vastly out-sustains Cassiopeia, healing and mitigating 1,008 more damage per minute. This massive durability gap means Nasus can absorb significant punishment and remain in lane while Cassiopeia is forced to recall. Building grievous wounds early is essential for Cassiopeia, and focusing on burst trade patterns rather than sustained fights is critical.

Best Cassiopeia Build Against Nasus

Boots of Swiftness is the optimal boots choice against Nasus, providing the mobility and stats Cassiopeia needs most in this matchup. The top-performing core items for Cassiopeia against Nasus are Liandry's Torment, Rylai's Crystal Scepter and Seraph's Embrace. This combination gives Cassiopeia an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 66.7% win rate across 3 games — well above average and making it the top item path against Nasus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Cassiopeia vs Nasus matchup.

Early Game vs Late Game

Early Game
Cassiopeia
100.0%
+100.0% advantage
Cassiopeia early game win rateCassiopeia100.0%
Nasus early game win rateNasus0.0%
Late Game
Cassiopeia
66.7%
+33.3% advantage
Cassiopeia late game win rateCassiopeia66.7%
Nasus late game win rateNasus33.3%

Cassiopeia dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Nasus. This lopsided early game means Cassiopeia can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Cassiopeia is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Nasus. Extended games heavily favor Cassiopeia, whose kit and scaling make them a dominant force in team fights and objective control.

Cassiopeia holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Nasus players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Cassiopeia Runes Against Nasus

Precision rune tree - Cassiopeia primary runes vs NasusPrecision
Conqueror - best Cassiopeia rune vs NasusPresence of Mind - best Cassiopeia rune vs NasusLegend: Haste - best Cassiopeia rune vs NasusLast Stand - best Cassiopeia rune vs Nasus
Sorcery rune tree - Cassiopeia secondary runes vs NasusSorcery
Manaflow Band - best Cassiopeia rune vs NasusTranscendence - best Cassiopeia rune vs Nasus
100.0% WR

Running Precision primary with Sorcery secondary allows Cassiopeia to press their advantage against Nasus, amplifying the strengths that make this a favorable matchup.


Cassiopeia matchup data for League of Legends patch 26.14. The table below shows Cassiopeia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Cassiopeia build, runes, laning stats, and early vs late game analysis for that specific matchup.

Cassiopeia matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
43.24%376.687710,50526.7%54.5%
50.00%305.986510,45845.5%52.6%
46.67%306.576610,53142.9%50.0%
48.28%296.596411,07356.3%38.5%
29.63%276.584211,42727.3%31.3%
56.52%235.565010,05440.0%69.2%
54.55%226.371710,75233.3%69.2%
66.67%216.37939,59277.8%58.3%
77.78%186.483212,09887.5%70.0%
41.18%176.285910,9870.0%63.6%
47.06%176.891610,67333.3%62.5%
58.82%176.888311,90250.0%66.7%
58.82%176.586211,85957.1%60.0%
41.18%176.169610,42414.3%60.0%
68.75%166.672512,820100.0%61.5%
25.00%166.664410,61922.2%28.6%
60.00%156.786412,06180.0%50.0%
28.57%145.294711,21520.0%33.3%
64.29%146.393715,587100.0%58.3%
30.77%137.266010,23833.3%28.6%
46.15%136.388711,89860.0%37.5%
38.46%136.074911,49325.0%44.4%
58.33%126.079110,35466.7%50.0%
18.18%116.481613,1240.0%20.0%
36.36%116.579511,10620.0%50.0%
45.45%116.469811,23660.0%33.3%
20.00%106.471010,02220.0%20.0%
77.78%96.196912,63266.7%83.3%
22.22%96.095414,9540.0%28.6%
77.78%97.08358,42185.7%50.0%
44.44%96.593012,24866.7%33.3%
66.67%96.81,03312,45566.7%66.7%
77.78%96.086413,088100.0%71.4%
37.50%86.696514,89433.3%40.0%
37.50%86.473911,89950.0%33.3%
57.14%77.41,13111,888100.0%40.0%
71.43%76.891011,39175.0%66.7%
42.86%76.791011,03033.3%50.0%
42.86%75.26188,80525.0%66.7%
42.86%77.297413,0710.0%75.0%
85.71%76.492914,88250.0%100.0%
0.00%75.96439,8530.0%0.0%
42.86%76.385110,5390.0%75.0%
85.71%76.81,02112,042100.0%66.7%
42.86%76.483311,76233.3%50.0%
57.14%76.39008,83866.7%50.0%
42.86%77.773510,61850.0%33.3%
57.14%75.68649,854100.0%0.0%
42.86%76.270312,07250.0%40.0%
57.14%76.77769,86875.0%33.3%
33.33%66.17299,1760.0%50.0%
16.67%64.871711,9290.0%20.0%
33.33%66.26488,58266.7%0.0%
33.33%66.35988,92025.0%50.0%
50.00%66.694713,80550.0%50.0%
16.67%66.07129,87933.3%0.0%
50.00%66.083412,8820.0%75.0%
33.33%66.495213,2040.0%40.0%
50.00%67.21,0929,78425.0%100.0%
20.00%56.072010,7890.0%33.3%
60.00%57.21,06212,03050.0%66.7%
40.00%56.569212,20150.0%33.3%
80.00%58.293011,461100.0%50.0%

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Cassiopeia vs Nasus - Frequently Asked Questions

How does Cassiopeia do against Nasus in League of Legends?

Cassiopeia wins the Cassiopeia vs Nasus matchup with a 85.7% win rate compared to Nasus's 14.3%, a 71.4 percentage point difference. This data is based on 7 recent ranked games in patch 26.14.

How does Cassiopeia do against Nasus in the early game?

In the early game, Cassiopeia has the advantage against Nasus with a 100.0% win rate versus 0.0%. Cassiopeia players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Cassiopeia do against Nasus in the late game?

In the late game, Cassiopeia takes over the Cassiopeia vs Nasus matchup with a 66.7% win rate compared to 33.3%. Cassiopeia scales better into team fights and objective contests after 25 minutes.

Who wins the Cassiopeia vs Nasus matchup?

Cassiopeia wins the matchup against Nasus with a 85.7% win rate in League of Legends patch 26.14. The 71.4 percentage point advantage means Cassiopeia is significantly favored in this lane matchup based on 7 games analyzed.

What is the best Cassiopeia build against Nasus?

The best Cassiopeia build against Nasus includes Liandry's Torment, Rylai's Crystal Scepter, Seraph's Embrace with Boots of Swiftness. This build achieves a 66.7% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Cassiopeia runes against Nasus?

The best Cassiopeia runes against Nasus use the Precision primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Cassiopeia vs Nasus matchup. See the full rune breakdown in the matchup comparison above.

Does Cassiopeia counter Nasus?

Yes, Cassiopeia has a favorable matchup against Nasus with a 85.7% win rate. Cassiopeia strongly counters Nasus in lane based on current patch 26.14 data.

How do I play Cassiopeia against Nasus?

When playing Cassiopeia against Nasus, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.