Cassiopeia - League of Legends Champion
Win Rate
50.3%
Pick Rate
0.7%

Cassiopeiavs Nasus

BMage
Patch26.5
Matches469,660
LaneAll Lanes
TierAll Tiers
Last UpdatedMar 12, 2026
MethodologyData Methodology

Cassiopeia vs Nasus is a decisive matchup in LoL patch 26.5. Nasus wins with a 62.5% win rate (+25.0%) over Cassiopeia based on 8 games. Nasus holds the advantage in both the early and late game. Below you'll find the best Cassiopeia build, runes, laning stats, and strategies for the Cassiopeia vs Nasus matchup.

Cassiopeia Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Cassiopeia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Nasus - 37.5% win rateNasus(37.5%)
Cassiopeia - 37.5% win rate in this matchup
Cassiopeia
37.5% WR
VS
Nasus vs Cassiopeia matchup - 62.5% win rate
Nasus
62.5% WR

Who Wins the Cassiopeia vs Nasus Matchup?

Nasus wins the Cassiopeia vs Nasus matchup
Winner
Nasus
Matches: 8
37.5%
Win Rate
62.5%
6.7
CS / min
6.6
885
DMG / min
670
11,605
Gold / game
12,415
267
Heal / min
480
632
DMG Mitigated / min
1,572
1.2
CC / min
0.6
40.0%
Early Game WR
60.0%
33.3%
Late Game WR
66.7%

Cassiopeia vs Nasus Matchup Summary

The Cassiopeia vs Nasus matchup is a decisive matchup in League of Legends ranked play. Based on 8 recent matches analyzed, Nasus wins with a 62.5% win rate compared to Cassiopeia's 37.5%, giving Nasus a 25.0 percentage point advantage. Nasus dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Cassiopeia players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Nasus leads by 1,152 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Nasus has a strong advantage in this matchup. Cassiopeia players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Nasus overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Cassiopeia vs Nasus Laning Phase Breakdown

Cassiopeia wins the laning phase against Nasus in League of Legends

Cassiopeia is favored during the laning phase against Nasus, winning 3 out of 5 key stat categories. Cassiopeia holds advantages in farming, damage and crowd control, making them the stronger laner in this matchup.

Farming
6.7Cassiopeia
6.6Nasus
Cassiopeia and Nasus farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
885Cassiopeia
670Nasus
Cassiopeia heavily out-damages Nasus by 215 DMG/min, dominating both short trades and all-in fights. Nasus should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Cassiopeia's sustained damage advantage take over.
Economy
11,605Cassiopeia
12,415Nasus
Nasus generates a commanding 810 more gold per game than Cassiopeia. This substantial economic advantage means Nasus consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Cassiopeia should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.2Cassiopeia
0.6Nasus
Cassiopeia provides 0.6 seconds more crowd control per minute than Nasus, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Cassiopeia coordinate with their jungler and control the pace of skirmishes.
Sustain
899Cassiopeia
2,051Nasus
Nasus vastly out-sustains Cassiopeia, healing and mitigating 1,152 more damage per minute. This massive durability gap means Nasus can absorb significant punishment and remain in lane while Cassiopeia is forced to recall. Building grievous wounds early is essential for Cassiopeia, and focusing on burst trade patterns rather than sustained fights is critical.

Best Cassiopeia Build Against Nasus

Boots of Swiftness is the optimal boots choice against Nasus, providing the mobility and stats Cassiopeia needs most in this matchup. The top-performing core items for Cassiopeia against Nasus are Rod of Ages, Liandry's Torment and Zhonya's Hourglass. This combination gives Cassiopeia an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Cassiopeia vs Nasus matchup.

Early Game vs Late Game

Early Game
Nasus
60.0%
+20.0% advantage
Cassiopeia early game win rateCassiopeia40.0%
Nasus early game win rateNasus60.0%
Late Game
Nasus
66.7%
+33.3% advantage
Cassiopeia late game win rateCassiopeia33.3%
Nasus late game win rateNasus66.7%

Nasus dominates the early game (first 15 minutes) with a commanding 60.0% win rate — a 20.0 percentage point lead over Cassiopeia. This lopsided early game means Nasus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Nasus is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Cassiopeia. Extended games heavily favor Nasus, whose kit and scaling make them a dominant force in team fights and objective control.

Nasus holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Cassiopeia players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Cassiopeia Runes Against Nasus

Precision rune tree - Cassiopeia primary runes vs NasusPrecision
Conqueror - best Cassiopeia rune vs NasusPresence of Mind - best Cassiopeia rune vs NasusLegend: Haste - best Cassiopeia rune vs NasusLast Stand - best Cassiopeia rune vs Nasus
Resolve rune tree - Cassiopeia secondary runes vs NasusResolve
Conditioning - best Cassiopeia rune vs NasusOvergrowth - best Cassiopeia rune vs Nasus
100.0% WR

The Precision and Resolve rune setup gives Cassiopeia the best tools to compete against Nasus in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Cassiopeia matchup data for League of Legends patch 26.5. The table below shows Cassiopeia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Cassiopeia build, runes, laning stats, and early vs late game analysis for that specific matchup.

Cassiopeia matchup win rates and stats in League of Legends patch 26.5
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
40.54%376.770111,21235.3%45.0%
73.08%266.489211,87266.7%78.6%
47.37%196.77859,87666.7%14.3%
50.00%166.277611,82040.0%54.5%
81.25%166.790213,12485.7%77.8%
50.00%146.493014,221100.0%36.4%
35.71%146.785511,80622.2%60.0%
50.00%145.987612,81620.0%66.7%
30.77%136.580313,74133.3%30.0%
46.15%136.67449,90040.0%50.0%
46.15%136.268712,18975.0%33.3%
61.54%135.88009,47257.1%66.7%
58.33%127.288112,49933.3%66.7%
58.33%126.686111,17133.3%83.3%
50.00%127.688211,65871.4%20.0%
27.27%117.26329,69828.6%25.0%
40.00%106.464110,20260.0%20.0%
60.00%106.36539,46566.7%50.0%
33.33%96.81,11413,0380.0%42.9%
55.56%96.284611,12766.7%33.3%
66.67%96.888012,16766.7%66.7%
66.67%96.31,12714,36850.0%71.4%
50.00%86.267010,65333.3%60.0%
37.50%87.278810,15833.3%50.0%
50.00%85.671210,55966.7%40.0%
37.50%86.788511,60540.0%33.3%
25.00%85.377311,3690.0%33.3%
42.86%77.578110,70550.0%33.3%
83.33%66.91,07711,883100.0%50.0%
50.00%67.496412,15733.3%66.7%
66.67%67.11,10015,3690.0%66.7%
33.33%67.47589,00440.0%0.0%
66.67%66.584410,90475.0%50.0%
66.67%65.681611,28150.0%75.0%
83.33%66.764412,117100.0%75.0%
60.00%56.57529,95966.7%50.0%
100.00%57.078913,086100.0%100.0%
40.00%55.976010,76433.3%50.0%
40.00%56.595412,8600.0%100.0%
80.00%55.890413,292100.0%66.7%
40.00%55.556610,0730.0%66.7%
40.00%57.21,01411,92050.0%33.3%
100.00%26.89507,998100.0%0.0%

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Cassiopeia vs Nasus - Frequently Asked Questions

How does Cassiopeia do against Nasus in League of Legends?

Nasus wins the Cassiopeia vs Nasus matchup with a 62.5% win rate compared to Cassiopeia's 37.5%, a 25.0 percentage point difference. This data is based on 8 recent ranked games in patch 26.5.

How does Cassiopeia do against Nasus in the early game?

In the early game, Nasus has the advantage against Cassiopeia with a 60.0% win rate versus 40.0%. Nasus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Cassiopeia do against Nasus in the late game?

In the late game, Nasus takes over the Cassiopeia vs Nasus matchup with a 66.7% win rate compared to 33.3%. Nasus scales better into team fights and objective contests after 25 minutes.

Who wins the Cassiopeia vs Nasus matchup?

Nasus wins the matchup against Cassiopeia with a 62.5% win rate in League of Legends patch 26.5. The 25.0 percentage point advantage means Nasus is significantly favored in this lane matchup based on 8 games analyzed.

What is the best Cassiopeia build against Nasus?

The best Cassiopeia build against Nasus includes Rod of Ages, Liandry's Torment, Zhonya's Hourglass with Boots of Swiftness. Check the matchup breakdown above for the full item path and build order.

What are the best Cassiopeia runes against Nasus?

The best Cassiopeia runes against Nasus use the Precision primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Cassiopeia vs Nasus matchup. See the full rune breakdown in the matchup comparison above.

Does Cassiopeia counter Nasus?

No, Cassiopeia struggles against Nasus with only a 37.5% win rate. Nasus has the advantage in this matchup. Cassiopeia players should focus on safe farming and avoiding extended trades to minimize Nasus's lead.

How do I play Cassiopeia against Nasus?

When playing Cassiopeia against Nasus, play cautiously and avoid Nasus's power spikes. Look for jungle assistance and team-dependent plays since Nasus has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.