Kai'Sa, League of Legends champion
Win Rate
49.0%
Pick Rate
6.4%
Ban Rate
2.8%

Kai'Sa vs Seraphine

Kai'Sa D TierMarksmanMage
Patch
26.19
Games
5,795
Lane
All Lanes
Tier
All Tiers
Last Updated
Oct 5, 2026 UTC
Methodology
Data Methodology

Kai'Sa vs Seraphine is a decisive matchup in LoL patch 26.19. Kai'Sa wins with a 55.6% win rate (+11.1%) over Seraphine based on 27 games. Kai'Sa holds the advantage in both the early and late game. Below you'll find the best Kai'Sa build, runes, laning stats, and strategies for the Kai'Sa vs Seraphine matchup.

Kai'Sa Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Kai'Sa performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Kai'Sa
Kai'Sa
57.4%
VS
Seraphine
42.6%
Seraphine

Who wins Kai'Sa vs Seraphine?

Slight Kai'Sa edgeLow confidence

Kai'Sa wins 57.4% of these games. With this many games the true rate is most likely between 43.3% and 70.5% (95% range).

Expected
49.4%
From both champions' overall Bot win rates
Matchup effect
+8.1 pts
Observed minus expected
Sample
47 games
Lane: Bot
vs patch 26.18
—
Not enough games on both patches

Lane: Bot · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.19 · Sep 24 – Sep 28

Key takeaways

  • Current data slightly favors Kai'Sa, but the sample is too limited for a strong conclusion: Kai'Sa wins 57.4% of 47 games (95% range 43.3–70.5%).
  • Both champions' overall Bot win rates predict 49.4% for Kai'Sa; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
  • Neither side reliably wins the lane: the average gold difference at 15 minutes is 241, within the margin of error (47 games).
  • Kai'Sa players pick Terminus far more often against Seraphine: 38.9% of their other Bot games, 59.6% here.
How we calculate this

Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.

A game only counts when Kai'Sa and Seraphine played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.

The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.

Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.

"What changes" compares Kai'Sa's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).

Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.

Kai'Sa vs Seraphine Laning Stats

Kai'SaSeraphine

At 15 minutes

Gold difference
+241
Within the margin of error
95% range −219 to +701
XP difference
−165
Within the margin of error
95% range −417 to +87
CS difference
+8.0
Kai'Sa ahead
95% range +2.1 to +14.0
2.87
Kills before 15 min
2.64
2.55
Deaths before 15 min
2.30
0.21
Solo kills before 15 min
0.17
10.6%
First blood
8.5%

Whole-game averages

6.9
CS / min
6.4
873
DMG / min
769
15,021
Gold / game
12,810
172
Heal / min
120
523
DMG Mitigated / min
395
0.1
CC / min
1.3

Kai'Sa vs Seraphine Win Rate by Game Length

Kai'Sa's win rate against Seraphine by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.

Too few games
Under 20 min
2 games
Too few games
20–25 min
7 games
Too few games
25–30 min
14 games
Too few games
30–35 min
10 games
Too few games
35+ min
14 games
Kai'Sa vs Seraphine95% rangeKai'Sa usual (Bot)

No game length stands out: Kai'Sa's results against Seraphine in short and long games are within the margin of error of each other.

Kai'Sa vs Seraphine Power Spikes

Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.

  1. Lane (15 min)EvenKai'Sa gold at 15: +241
  2. First itemSeraphineKai'Sa: 12.3 min · Seraphine: 11.5 min
  3. Games under 20 minInsufficient data
  4. 20–30 min gamesInsufficient data
  5. 30+ min gamesInsufficient data

What Kai'Sa Changes Against Seraphine

Choices Kai'Sa players make noticeably more or less often in this matchup than in their other Bot games.

  • Terminus
    Usually
    38.9%
    vs Seraphine
    59.6%
    +20.7 pts60.7% WR here
  • Statikk Shiv
    Usually
    35.7%
    vs Seraphine
    21.3%
    −14.4 pts
  • Bloodthirster
    Usually
    1.5%
    vs Seraphine
    6.4%
    +4.9 pts
  • Celerity
    Usually
    0.7%
    vs Seraphine
    4.3%
    +3.6 pts

Best Kai'Sa Build vs Seraphine

Against Seraphine

Not enough matchup-specific build data: only 12 of 37 Kai'Sa games against Seraphine carried a complete build, which is too few to recommend an item path from. Use Kai'Sa's standard build instead.

  • Kai'Sa usually completes Kraken Slayer first, at 12.3 min (median of 35 games).
  • Seraphine usually completes Blackfire Torch first, at 11.5 min (median of 30 games).
  • Skill priority: Q > E > W — the same as usual.

Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.

Best Kai'Sa Runes vs Seraphine

Usual Kai'Sa runes (Bot)

Lethal TempoLethal Tempo
Precision
Presence of MindLegend: BloodlineCoup de Grace
Inspiration
Magical FootwearTriple Tonic
Attack Speed (offense)Adaptive Force (flex)Health Scaling (defense)

70.4% win rate · 27 games

Against Seraphine

Too few games for a matchup-specific rune page yet — use the usual page.

MetaBot Desktop

Plan your Kai'Sa draft in Draft Lab

Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.

  • Full 5v5 draft board
  • Lane matchup win rates
  • Pick and ban suggestions
Draft Lab in MetaBot Desktop

Kai'Sa matchup data for League of Legends patch 26.19. The table below shows Kai'Sa's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Kai'Sa build, runes, laning stats, and early vs late game analysis for that specific matchup.

Other Kai'Sa Matchups

Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.

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Kai'Sa vs Seraphine FAQ - Patch 26.19

Who wins Kai'Sa vs Seraphine?

Current data slightly favors Kai'Sa, but the sample is too limited for a strong conclusion: Kai'Sa wins 57.4% of 47 games (95% range 43.3–70.5%).

What is Kai'Sa's win rate against Seraphine?

Kai'Sa wins 57.4% of 47 Bot games against Seraphine on patch 26.19 (95% range 43.3–70.5%). Based on both champions' overall Bot win rates, 49.4% would be expected.

Does Kai'Sa counter Seraphine?

Not clearly. Kai'Sa wins 57.4% of 47 games against Seraphine, and the 95% range (43.3–70.5%) includes 50%, so neither champion reliably counters the other on current data.

Who wins lane, Kai'Sa or Seraphine?

Neither side reliably wins the lane: the average gold difference at 15 minutes is 241, within the margin of error (47 games).

Does Kai'Sa outscale Seraphine?

There are too few games of each length to tell yet.

When is Seraphine strongest against Kai'Sa?

Seraphine is measurably ahead in: First item.

What should Kai'Sa build against Seraphine?

There are not enough games for a matchup-specific core, so use Kai'Sa's usual Bot core: Runaan's Hurricane, Lord Dominik's Regards, Yun Tal Wildarrows. The biggest change against Seraphine: Terminus (38.9% usually, 59.6% here).

What runes should Kai'Sa use against Seraphine?

Use Kai'Sa's usual Lethal Tempo page (Precision + Inspiration); there are too few games for a matchup-specific page. The biggest change against Seraphine: Celerity (0.7% usually, 4.3% here).