Seraphine - League of Legends Champion
Win Rate
52.4%
Pick Rate
10.0%

Seraphinevs Senna

SSupportMage
Patch26.14
Matches226,800
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Seraphine vs Senna is a moderate matchup in LoL patch 26.14. Senna wins with a 51.7% win rate (+3.4%) over Seraphine based on 147 games. Seraphine wins the early laning phase while Senna scales better into the late game. Below you'll find the best Seraphine build, runes, laning stats, and strategies for the Seraphine vs Senna matchup.

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Seraphine Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Seraphine performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 48.3% win rate in this matchup
Seraphine
48.3% WR
VS
Senna vs Seraphine matchup - 51.7% win rate
Senna
51.7% WR

Who Wins the Seraphine vs Senna Matchup?

Senna wins the Seraphine vs Senna matchup
Winner
Senna
Matches: 147
48.3%
Win Rate
51.7%
1.9
CS / min
2.0
532
DMG / min
606
9,706
Gold / game
10,696
251
Heal / min
442
379
DMG Mitigated / min
338
1.2
CC / min
1.2
51.0%
Early Game WR
49.0%
46.9%
Late Game WR
53.1%

Seraphine vs Senna Matchup Summary

The Seraphine vs Senna matchup is a moderate matchup in League of Legends ranked play. Based on 147 recent matches analyzed, Senna wins with a 51.7% win rate compared to Seraphine's 48.3%, giving Senna a 3.4 percentage point advantage. Game phase dynamics play a critical role here: Seraphine controls the early laning stage, but Senna outscales as the game goes longer. The matchup shifts dramatically depending on game length — Seraphine needs to press advantages before Senna reaches their power spikes, while Senna should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Senna leads by 150 HP/min — a difference that heavily influences the outcome of trades and skirmishes. While Senna is slightly favored, Seraphine can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Senna's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Seraphine vs Senna Laning Phase Breakdown

Senna wins the laning phase against Seraphine in League of Legends

Senna is favored during the laning phase against Seraphine, winning 4 out of 5 key stat categories. Senna holds advantages in farming, damage, gold income and sustain, making them the stronger laner in this matchup.

Farming
1.9Seraphine
2.0Senna
Seraphine and Senna farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
532Seraphine
606Senna
Senna deals 73 more champion damage per minute than Seraphine. While noticeable in extended trades, this gap can be offset by Seraphine choosing favorable fight windows, such as engaging when Senna's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
9,706Seraphine
10,696Senna
Senna generates a commanding 990 more gold per game than Seraphine. This substantial economic advantage means Senna consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Seraphine should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.2Seraphine
1.2Senna
Both Seraphine and Senna provide similar amounts of crowd control (0.0s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
630Seraphine
780Senna
Senna vastly out-sustains Seraphine, healing and mitigating 150 more damage per minute. This massive durability gap means Senna can absorb significant punishment and remain in lane while Seraphine is forced to recall. Building grievous wounds early is essential for Seraphine, and focusing on burst trade patterns rather than sustained fights is critical.

Best Seraphine Build Against Senna

Ionian Boots of Lucidity is the optimal boots choice against Senna, providing the mobility and stats Seraphine needs most in this matchup. The top-performing core items for Seraphine against Senna are Echoes of Helia, Moonstone Renewer and Rylai's Crystal Scepter. This combination gives Seraphine an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 71.4% win rate across 7 games — well above average and making it the top item path against Senna. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Seraphine vs Senna matchup.

Early Game vs Late Game

Early Game
Seraphine
51.0%
+2.0% advantage
Seraphine early game win rateSeraphine51.0%
Senna early game win rateSenna49.0%
Late Game
Senna
53.1%
+6.3% advantage
Seraphine late game win rateSeraphine46.9%
Senna late game win rateSenna53.1%

The early game (first 15 minutes) is a toss-up between Seraphine and Senna, with Seraphine holding a razor-thin 51.0% win rate edge (+2.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Senna is far superior in the late game (25+ minutes), boasting a 53.1% win rate — 6.3 points above Seraphine. Extended games heavily favor Senna, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Seraphine has the edge early, but Senna gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Seraphine Runes Against Senna

Sorcery rune tree - Seraphine primary runes vs SennaSorcery
Arcane Comet - best Seraphine rune vs SennaManaflow Band - best Seraphine rune vs SennaTranscendence - best Seraphine rune vs SennaScorch - best Seraphine rune vs Senna
Inspiration rune tree - Seraphine secondary runes vs SennaInspiration
Biscuit Delivery - best Seraphine rune vs SennaCosmic Insight - best Seraphine rune vs Senna
60.0% WR

The Sorcery and Inspiration rune setup gives Seraphine the best tools to compete against Senna in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Seraphine matchup data for League of Legends patch 26.14. The table below shows Seraphine's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Seraphine build, runes, laning stats, and early vs late game analysis for that specific matchup.

Seraphine matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
55.85%2991.74719,29548.1%60.0%
49.76%2071.55128,84357.0%45.3%
47.70%1741.55109,00848.0%47.4%
49.13%1731.44618,48850.0%48.5%
49.12%1711.64808,75953.7%46.1%
47.06%1531.55109,22549.1%45.8%
48.30%1471.95329,70651.0%46.9%
50.38%1331.54679,03049.0%51.2%
45.97%1241.44288,53360.0%36.5%
48.21%1121.44729,01753.3%44.8%
54.55%1102.35059,68744.4%59.5%
46.79%1091.55018,61150.0%44.4%
57.41%1081.45369,50765.8%52.2%
55.32%941.85399,07347.4%60.7%
50.56%891.44849,28360.0%45.8%
52.87%871.34668,26252.8%52.9%
57.65%851.54169,35765.6%52.8%
57.50%805.372411,20659.3%56.6%
45.45%771.64769,99525.0%50.8%
63.16%761.55059,33854.8%68.9%
57.89%761.75148,58067.6%48.7%
50.00%721.64569,53364.0%42.5%
50.00%662.04959,25747.8%51.2%
50.77%651.46317,61950.0%51.6%
53.85%656.077710,54060.0%48.6%
46.88%641.34479,18159.1%40.5%
52.46%611.54608,55950.0%54.0%
51.72%581.45178,94657.7%46.9%
53.45%581.35148,75145.5%58.3%
43.86%571.45249,59460.0%38.1%
54.55%551.55419,53777.8%43.2%
52.83%531.44887,86337.5%65.5%
52.94%513.765010,65950.0%54.3%
53.49%436.17089,63055.2%50.0%
56.10%411.44789,02957.1%55.0%
36.84%385.975311,16633.3%38.5%
51.52%331.55048,36043.8%58.8%
54.55%331.44978,85036.4%63.6%
62.50%325.476410,80441.7%75.0%
35.48%311.54698,95836.4%35.0%
54.84%311.94618,75463.6%50.0%
55.17%293.267211,13925.0%66.7%
60.71%284.15919,88872.7%52.9%
32.14%286.176410,58033.3%31.3%
69.23%265.776110,57085.7%50.0%
70.83%241.45079,19650.0%81.3%
56.52%236.182912,78350.0%60.0%
56.52%231.85069,03258.3%54.5%
47.62%213.564410,63366.7%40.0%
57.14%211.66148,42960.0%54.5%
42.86%211.648511,10033.3%44.4%
63.16%195.569112,81460.0%64.3%
63.16%191.75289,58566.7%60.0%
47.37%196.387810,25960.0%33.3%
50.00%186.580110,04650.0%50.0%
50.00%186.280711,85837.5%60.0%
50.00%186.885311,27550.0%50.0%
56.25%165.472113,6070.0%69.2%
50.00%164.861610,99950.0%50.0%
56.25%165.866011,976100.0%36.4%
75.00%162.24547,74077.8%71.4%
80.00%152.472410,151100.0%66.7%
66.67%152.474310,11660.0%70.0%
42.86%145.879310,92340.0%44.4%
61.54%131.44069,43660.0%62.5%
66.67%126.279211,77420.0%100.0%
33.33%125.16559,89640.0%28.6%
54.55%113.46429,30060.0%50.0%
40.00%101.35288,42020.0%60.0%
40.00%105.289411,60625.0%50.0%
80.00%102.254811,212100.0%71.4%
55.56%94.86278,88680.0%25.0%
44.44%96.47018,84342.9%50.0%
55.56%91.655510,08533.3%66.7%
25.00%85.075011,78850.0%16.7%
85.71%75.55249,75775.0%100.0%
57.14%71.55089,13366.7%50.0%
42.86%75.566910,94833.3%50.0%
85.71%76.187613,23166.7%100.0%
42.86%74.36429,62220.0%100.0%
57.14%73.050210,97250.0%60.0%
57.14%72.667710,02866.7%50.0%
71.43%73.04619,27766.7%75.0%
28.57%73.673212,7790.0%33.3%
66.67%65.886412,97750.0%75.0%
50.00%64.85639,34966.7%33.3%
33.33%66.786113,96850.0%25.0%
66.67%65.56098,223100.0%0.0%
83.33%64.062711,888100.0%80.0%
50.00%64.249210,633100.0%25.0%
100.00%64.68619,415100.0%100.0%
80.00%52.45339,18466.7%100.0%
60.00%51.55748,068100.0%33.3%
80.00%55.787512,964100.0%75.0%
40.00%51.64836,62350.0%33.3%
60.00%53.08026,67733.3%100.0%
100.00%52.36298,546100.0%100.0%
60.00%54.26028,77833.3%100.0%
60.00%54.74626,532100.0%33.3%
40.00%56.485013,194100.0%0.0%
20.00%53.473711,9840.0%33.3%
100.00%55.51,02313,201100.0%100.0%

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Seraphine vs Senna - Frequently Asked Questions

How does Seraphine do against Senna in League of Legends?

Senna wins the Seraphine vs Senna matchup with a 51.7% win rate compared to Seraphine's 48.3%, a 3.4 percentage point difference. This data is based on 147 recent ranked games in patch 26.14.

How does Seraphine do against Senna in the early game?

In the early game, Seraphine has the advantage against Senna with a 51.0% win rate versus 49.0%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Seraphine do against Senna in the late game?

In the late game, Senna takes over the Seraphine vs Senna matchup with a 53.1% win rate compared to 46.9%. Senna scales better into team fights and objective contests after 25 minutes.

Who wins the Seraphine vs Senna matchup?

Senna wins the matchup against Seraphine with a 51.7% win rate in League of Legends patch 26.14. The 3.4 percentage point advantage means Senna is moderately favored in this lane matchup based on 147 games analyzed.

What is the best Seraphine build against Senna?

The best Seraphine build against Senna includes Echoes of Helia, Moonstone Renewer, Rylai's Crystal Scepter with Ionian Boots of Lucidity. This build achieves a 71.4% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Seraphine runes against Senna?

The best Seraphine runes against Senna use the Sorcery primary tree with Inspiration secondary. This rune setup achieves a 60.0% win rate in the Seraphine vs Senna matchup. See the full rune breakdown in the matchup comparison above.

Does Seraphine counter Senna?

No, Seraphine struggles against Senna with only a 48.3% win rate. Senna has the advantage in this matchup. Seraphine players should focus on safe farming and avoiding extended trades to minimize Senna's lead.

How do I play Seraphine against Senna?

When playing Seraphine against Senna, play cautiously and avoid Senna's power spikes. Look for jungle assistance and team-dependent plays since Senna has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.