Vayne - League of Legends Champion
Win Rate
49.5%
Pick Rate
5.3%

Vaynevs Ambessa

DMarksmanAssassin
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 21, 2026
MethodologyData Methodology

Vayne vs Ambessa is a very close matchup in LoL patch 26.7. Vayne wins with a 50.0% win rate (+0.0%) over Ambessa based on 18 games. Ambessa wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Ambessa matchup.

Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Ambessa - 50.0% win rateAmbessa(50.0%)
Vayne - 50.0% win rate in this matchup
Vayne
50.0% WR
VS
Ambessa vs Vayne matchup - 50.0% win rate
Ambessa
50.0% WR

Who Wins the Vayne vs Ambessa Matchup?

Vayne wins the Vayne vs Ambessa matchup
Winner
Vayne
Matches: 18
50.0%
Win Rate
50.0%
5.8
CS / min
5.6
754
DMG / min
860
12,373
Gold / game
12,425
238
Heal / min
235
524
DMG Mitigated / min
1,340
0.3
CC / min
0.5
28.6%
Early Game WR
71.4%
63.6%
Late Game WR
36.4%

Vayne vs Ambessa Matchup Summary

The Vayne vs Ambessa matchup is essentially a coin-flip matchup in League of Legends ranked play. Based on 18 recent matches analyzed, Vayne wins with a 50.0% win rate compared to Ambessa's 50.0%, giving Vayne a 0.0 percentage point advantage. Game phase dynamics play a critical role here: Ambessa controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Ambessa needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Ambessa leads by 814 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a statistical edge, but the margin is close enough that respecting Ambessa's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Ambessa Laning Phase Breakdown

Ambessa wins the laning phase against Vayne in League of Legends

Ambessa is favored during the laning phase against Vayne, winning 4 out of 5 key stat categories. Ambessa holds advantages in damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
5.8Vayne
5.6Ambessa
Vayne and Ambessa farm at nearly identical rates in this matchup, with only a 0.2 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
754Vayne
860Ambessa
Ambessa heavily out-damages Vayne by 106 DMG/min, dominating both short trades and all-in fights. Vayne should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Ambessa's sustained damage advantage take over.
Economy
12,373Vayne
12,425Ambessa
Vayne and Ambessa generate nearly equal gold per game, with just a 52 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
0.3Vayne
0.5Ambessa
Both Vayne and Ambessa provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
762Vayne
1,575Ambessa
Ambessa vastly out-sustains Vayne, healing and mitigating 814 more damage per minute. This massive durability gap means Ambessa can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Ambessa

Berserker's Greaves is the optimal boots choice against Ambessa, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Ambessa are Essence Reaver, Stormrazor and Experimental Hexplate. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 66.7% win rate across 3 games — well above average and making it the top item path against Ambessa. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Ambessa matchup.

Early Game vs Late Game

Early Game
Ambessa
71.4%
+42.9% advantage
Vayne early game win rateVayne28.6%
Ambessa early game win rateAmbessa71.4%
Late Game
Vayne
63.6%
+27.3% advantage
Vayne late game win rateVayne63.6%
Ambessa late game win rateAmbessa36.4%

Ambessa dominates the early game (first 15 minutes) with a commanding 71.4% win rate — a 42.9 percentage point lead over Vayne. This lopsided early game means Ambessa can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Vayne is far superior in the late game (25+ minutes), boasting a 63.6% win rate — 27.3 points above Ambessa. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Ambessa must aggressively press their early advantage and close out the game before Vayne reaches their scaling breakpoints. If Vayne survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Vayne Runes Against Ambessa

Precision rune tree - Vayne primary runes vs AmbessaPrecision
Fleet Footwork - best Vayne rune vs AmbessaAbsorb Life - best Vayne rune vs AmbessaLegend: Alacrity - best Vayne rune vs AmbessaCut Down - best Vayne rune vs Ambessa
Sorcery rune tree - Vayne secondary runes vs AmbessaSorcery
Celerity - best Vayne rune vs AmbessaNimbus Cloak - best Vayne rune vs Ambessa
100.0% WR

The Precision primary with Sorcery secondary combination helps Vayne maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Ambessa.


Vayne matchup data for League of Legends patch 26.7. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.02%3576.081713,23145.3%52.0%
52.47%3246.289813,59649.3%55.2%
48.09%3146.283212,81944.0%52.7%
49.01%3025.982512,93747.5%50.3%
52.94%2726.083913,07152.8%53.1%
45.37%2276.496014,25446.9%44.2%
50.00%2226.493713,71750.0%50.0%
52.71%2036.585613,74148.9%56.0%
52.32%1516.582813,28755.4%49.4%
58.39%1496.695312,70051.6%63.5%
51.30%1155.881313,71761.5%42.9%
47.71%1096.088213,23938.2%57.4%
55.67%976.488012,62559.6%51.1%
51.55%976.380612,73552.5%50.0%
50.00%945.983213,59546.7%53.1%
36.36%886.279012,98330.0%41.7%
47.44%786.692813,28446.3%48.6%
61.33%756.692412,10266.7%55.6%
55.56%726.185813,24745.2%63.4%
57.35%686.085313,57456.0%58.1%
36.76%686.288112,39436.7%36.8%
52.54%596.383712,51848.5%57.7%
42.37%596.287012,82834.4%51.9%
38.60%575.760511,22540.0%37.0%
37.50%565.560110,77030.4%42.4%
43.40%536.21,04512,46744.4%42.3%
44.00%506.188613,06147.8%40.7%
53.06%496.11,21413,80450.0%55.2%
65.91%446.186913,29266.7%65.4%
56.82%445.692114,04761.1%53.9%
43.18%445.799611,54831.3%50.0%
50.00%406.384813,58435.3%60.9%
55.00%405.989314,58823.1%70.4%
57.50%406.395114,24860.0%56.7%
48.72%396.595213,49157.9%40.0%
57.89%386.01,02912,41355.0%61.1%
42.11%386.192313,74144.4%40.0%
54.05%377.092811,69252.4%56.3%
40.54%375.880412,22541.2%40.0%
40.00%355.71,14111,80838.9%41.2%
55.88%346.585611,12557.9%53.3%
50.00%326.098613,59966.7%43.5%
66.67%306.289612,54050.0%81.3%
56.67%306.298113,89653.9%58.8%
48.28%296.785812,18028.6%66.7%
55.17%296.31,02413,69462.5%46.1%
51.85%275.798412,39145.5%56.3%
61.54%266.185111,71961.5%61.5%
64.00%256.080811,77055.6%68.8%
44.00%256.892712,26342.9%45.5%
33.33%246.483511,60541.7%25.0%
56.52%235.592112,42462.5%53.3%
43.48%236.383712,92160.0%30.8%
40.91%226.678811,10141.7%40.0%
52.38%215.992313,47740.0%63.6%
60.00%205.290914,35220.0%73.3%
47.37%196.91,00811,89263.6%25.0%
50.00%186.273213,04560.0%37.5%
50.00%186.21,05312,78455.6%44.4%
44.44%186.483711,79542.9%45.5%
50.00%185.875412,37328.6%63.6%
76.47%176.91,02114,29680.0%75.0%
29.41%176.982911,89737.5%22.2%
41.18%176.086215,19160.0%33.3%
43.75%166.083811,77362.5%25.0%
56.25%166.690711,52757.1%55.6%
37.50%165.465913,20816.7%50.0%
68.75%166.793713,92583.3%60.0%
53.33%155.968611,41937.5%71.4%
73.33%156.485112,62177.8%66.7%
50.00%145.785111,11416.7%75.0%
42.86%144.364512,05114.3%71.4%
53.85%133.388514,16275.0%44.4%
53.85%135.71,05513,76250.0%55.6%
58.33%125.656210,02757.1%60.0%
25.00%124.586213,08325.0%25.0%
50.00%126.378413,32833.3%66.7%
27.27%116.277113,46233.3%25.0%
63.64%116.387415,82666.7%62.5%
36.36%116.665110,70650.0%20.0%
45.45%115.591912,62950.0%40.0%
72.73%116.474510,85071.4%75.0%
45.45%116.01,06414,50840.0%50.0%
70.00%106.699613,49075.0%66.7%
40.00%106.887613,21633.3%50.0%
55.56%96.393712,28633.3%100.0%
44.44%96.21,07715,702100.0%28.6%
33.33%96.877411,06920.0%50.0%
25.00%85.569310,37825.0%25.0%
50.00%85.99738,78533.3%100.0%
37.50%81.983414,72733.3%40.0%
42.86%75.690112,809100.0%20.0%
0.00%76.655810,7000.0%0.0%
42.86%74.665114,53850.0%40.0%
71.43%76.168213,12675.0%66.7%
57.14%75.588812,31625.0%100.0%
57.14%75.489512,10050.0%66.7%
42.86%74.077311,64333.3%50.0%
57.14%72.51,31315,57625.0%100.0%
33.33%64.65709,10525.0%50.0%
66.67%65.91,08915,49350.0%75.0%
50.00%65.776213,18250.0%50.0%
50.00%61.989114,832100.0%40.0%
16.67%65.384410,4420.0%33.3%
0.00%65.979510,7240.0%0.0%
83.33%66.196311,361100.0%50.0%
50.00%66.380413,574100.0%40.0%
40.00%54.793914,778100.0%0.0%
60.00%51.71,19517,6480.0%75.0%
20.00%51.56919,37833.3%0.0%
60.00%55.31,10015,380100.0%50.0%
20.00%56.891512,5530.0%33.3%
40.00%56.51,02117,6030.0%40.0%

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Vayne vs Ambessa - Frequently Asked Questions

How does Vayne do against Ambessa in League of Legends?

Vayne wins the Vayne vs Ambessa matchup with a 50.0% win rate compared to Ambessa's 50.0%, a 0.0 percentage point difference. This data is based on 18 recent ranked games in patch 26.7.

How does Vayne do against Ambessa in the early game?

In the early game, Ambessa has the advantage against Vayne with a 71.4% win rate versus 28.6%. Ambessa players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Ambessa in the late game?

In the late game, Vayne takes over the Vayne vs Ambessa matchup with a 63.6% win rate compared to 36.4%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Ambessa matchup?

Vayne wins the matchup against Ambessa with a 50.0% win rate in League of Legends patch 26.7. The 0.0 percentage point advantage means Vayne is slightly favored in this lane matchup based on 18 games analyzed.

What is the best Vayne build against Ambessa?

The best Vayne build against Ambessa includes Essence Reaver, Stormrazor, Experimental Hexplate with Berserker's Greaves. This build achieves a 66.7% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Ambessa?

The best Vayne runes against Ambessa use the Precision primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Ambessa matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Ambessa?

Yes, Vayne has a favorable matchup against Ambessa with a 50.0% win rate. Vayne slightly edges out Ambessa in lane based on current patch 26.7 data.

How do I play Vayne against Ambessa?

When playing Vayne against Ambessa, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Ambessa. Build the recommended items and runes for this specific matchup for the best results.