Vayne - League of Legends Champion
Win Rate
47.9%
Pick Rate
4.8%

Vaynevs Brand

FMarksmanAssassin
Patch26.14
Matches134,440
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 20, 2026
MethodologyData Methodology

Vayne vs Brand is a decisive matchup in LoL patch 26.14. Brand wins with a 66.7% win rate (+33.3%) over Vayne based on 6 games. Vayne wins the early laning phase while Brand scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Brand matchup.

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Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 33.3% win rate in this matchup
Vayne
33.3% WR
VS
Brand vs Vayne matchup - 66.7% win rate
Brand
66.7% WR

Who Wins the Vayne vs Brand Matchup?

Brand wins the Vayne vs Brand matchup
Winner
Brand
Matches: 6
33.3%
Win Rate
66.7%
6.2
CS / min
5.9
903
DMG / min
893
13,024
Gold / game
10,625
230
Heal / min
114
454
DMG Mitigated / min
304
0.4
CC / min
0.9
50.0%
Early Game WR
50.0%
25.0%
Late Game WR
75.0%

Vayne vs Brand Matchup Summary

The Vayne vs Brand matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Brand wins with a 66.7% win rate compared to Vayne's 33.3%, giving Brand a 33.3 percentage point advantage. Game phase dynamics play a critical role here: Vayne controls the early laning stage, but Brand outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vayne needs to press advantages before Brand reaches their power spikes, while Brand should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Brand leads by 0.5s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Brand has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Brand overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Brand Laning Phase Breakdown

Vayne wins the laning phase against Brand in League of Legends

Vayne is favored during the laning phase against Brand, winning 4 out of 5 key stat categories. Vayne holds advantages in farming, damage, gold income and sustain, making them the stronger laner in this matchup.

Farming
6.2Vayne
5.9Brand
Vayne and Brand farm at nearly identical rates in this matchup, with only a 0.2 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
903Vayne
893Brand
Damage output is virtually even between Vayne and Brand, with only 10 DMG/min separating them. Fights in this matchup are decided more by ability timing and positioning than raw damage numbers, making mechanical skill the deciding factor in trades.
Economy
13,024Vayne
10,625Brand
Vayne generates a commanding 2,399 more gold per game than Brand. This substantial economic advantage means Vayne consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Brand should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.4Vayne
0.9Brand
Brand provides 0.5 seconds more crowd control per minute than Vayne, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Brand coordinate with their jungler and control the pace of skirmishes.
Sustain
684Vayne
418Brand
Vayne vastly out-sustains Brand, healing and mitigating 265 more damage per minute. This massive durability gap means Vayne can absorb significant punishment and remain in lane while Brand is forced to recall. Building grievous wounds early is essential for Brand, and focusing on burst trade patterns rather than sustained fights is critical.

Early Game vs Late Game

Early Game
Vayne
50.0%
+0.0% advantage
Vayne early game win rateVayne50.0%
Brand early game win rateBrand50.0%
Late Game
Brand
75.0%
+50.0% advantage
Vayne late game win rateVayne25.0%
Brand late game win rateBrand75.0%

The early game (first 15 minutes) is a toss-up between Vayne and Brand, with Vayne holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Brand is far superior in the late game (25+ minutes), boasting a 75.0% win rate — 50.0 points above Vayne. Extended games heavily favor Brand, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Vayne has the edge early, but Brand gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Vayne Runes Against Brand

Precision rune tree - Vayne primary runes vs BrandPrecision
Lethal Tempo - best Vayne rune vs BrandTriumph - best Vayne rune vs BrandLegend: Alacrity - best Vayne rune vs BrandCoup de Grace - best Vayne rune vs Brand
Resolve rune tree - Vayne secondary runes vs BrandResolve
Conditioning - best Vayne rune vs BrandOvergrowth - best Vayne rune vs Brand
100.0% WR

The Precision and Resolve rune setup gives Vayne the best tools to compete against Brand in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Vayne matchup data for League of Legends patch 26.14. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
48.39%935.883812,74245.2%50.0%
46.99%836.385412,66042.9%50.0%
53.01%835.987313,59358.1%50.0%
48.72%786.286213,82135.0%53.5%
46.77%626.382510,60241.7%53.9%
36.54%526.173912,14111.1%50.0%
51.02%496.494213,18130.0%65.5%
33.33%426.382113,28025.0%36.7%
51.61%316.181612,32450.0%52.4%
40.00%306.080211,18235.7%43.8%
40.00%306.388012,92944.4%38.1%
41.67%246.093713,41744.4%40.0%
43.48%235.970411,49130.0%53.9%
59.09%226.281411,07366.7%53.9%
50.00%205.790912,85257.1%46.1%
26.32%195.776910,39020.0%33.3%
57.89%196.390411,95150.0%63.6%
63.16%196.275310,65175.0%42.9%
61.11%185.888013,02580.0%53.9%
41.18%175.875611,40716.7%54.5%
66.67%155.581111,03883.3%55.6%
40.00%156.088714,12640.0%40.0%
42.86%146.375812,37728.6%57.1%
50.00%146.31,08313,08740.0%55.6%
50.00%146.671411,38233.3%80.0%
57.14%146.01,01611,73057.1%57.1%
46.15%136.880711,33428.6%66.7%
84.62%136.81,30913,21880.0%87.5%
38.46%135.87979,95022.2%75.0%
61.54%136.375715,01433.3%70.0%
33.33%126.589715,6330.0%40.0%
72.73%115.969612,05150.0%85.7%
40.00%106.082811,0040.0%57.1%
30.00%105.91,09210,36820.0%40.0%
40.00%105.375111,0470.0%66.7%
77.78%97.079010,74683.3%66.7%
66.67%96.11,02415,000100.0%62.5%
44.44%96.178013,51650.0%42.9%
37.50%86.594812,7660.0%60.0%
50.00%86.38268,12950.0%50.0%
71.43%76.01,24813,755100.0%60.0%
71.43%77.21,35616,04850.0%80.0%
66.67%66.785212,325100.0%50.0%
16.67%65.996912,6300.0%33.3%
66.67%65.765712,40550.0%75.0%
33.33%66.290313,02450.0%25.0%
50.00%66.583813,1700.0%75.0%
66.67%66.694911,83950.0%75.0%
50.00%66.097112,154100.0%40.0%
33.33%67.475312,492100.0%20.0%
66.67%63.61,00510,165100.0%0.0%
33.33%65.772612,8680.0%40.0%
50.00%66.41,18513,5870.0%60.0%
40.00%56.083912,463100.0%25.0%
40.00%56.01,05714,8920.0%50.0%
40.00%55.974410,886100.0%25.0%
40.00%55.399213,924100.0%25.0%
40.00%55.71,01014,069100.0%25.0%

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Vayne vs Brand - Frequently Asked Questions

How does Vayne do against Brand in League of Legends?

Brand wins the Vayne vs Brand matchup with a 66.7% win rate compared to Vayne's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.14.

How does Vayne do against Brand in the early game?

In the early game, Vayne has the advantage against Brand with a 50.0% win rate versus 50.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Brand in the late game?

In the late game, Brand takes over the Vayne vs Brand matchup with a 75.0% win rate compared to 25.0%. Brand scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Brand matchup?

Brand wins the matchup against Vayne with a 66.7% win rate in League of Legends patch 26.14. The 33.3 percentage point advantage means Brand is significantly favored in this lane matchup based on 6 games analyzed.

What is the best Vayne build against Brand?

The best Vayne build against Brand includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Brand?

The best Vayne runes against Brand use the Precision primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Brand matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Brand?

No, Vayne struggles against Brand with only a 33.3% win rate. Brand has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Brand's lead.

How do I play Vayne against Brand?

When playing Vayne against Brand, play cautiously and avoid Brand's power spikes. Look for jungle assistance and team-dependent plays since Brand has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.