Vayne - League of Legends Champion
Win Rate
49.5%
Pick Rate
5.3%

Vaynevs Brand

DMarksmanAssassin
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 19, 2026
MethodologyData Methodology

Vayne vs Brand is a decisive matchup in LoL patch 26.7. Brand wins with a 56.0% win rate (+12.0%) over Vayne based on 50 games. Brand holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Brand matchup.

Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Brand - 44.0% win rateBrand(44.0%)
Vayne - 44.0% win rate in this matchup
Vayne
44.0% WR
VS
Brand vs Vayne matchup - 56.0% win rate
Brand
56.0% WR

Who Wins the Vayne vs Brand Matchup?

Brand wins the Vayne vs Brand matchup
Winner
Brand
Matches: 50
44.0%
Win Rate
56.0%
6.1
CS / min
6.4
886
DMG / min
1,089
13,061
Gold / game
13,047
231
Heal / min
90
499
DMG Mitigated / min
378
0.3
CC / min
1.4
47.8%
Early Game WR
52.2%
40.7%
Late Game WR
59.3%

Vayne vs Brand Matchup Summary

The Vayne vs Brand matchup is a decisive matchup in League of Legends ranked play. Based on 50 recent matches analyzed, Brand wins with a 56.0% win rate compared to Vayne's 44.0%, giving Brand a 12.0 percentage point advantage. Brand dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Brand leads by 1.0s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Brand has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Brand overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Brand Laning Phase Breakdown

Brand wins the laning phase against Vayne in League of Legends

Brand is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Brand holds advantages in farming, damage and crowd control, making them the stronger laner in this matchup.

Farming
6.1Vayne
6.4Brand
Brand edges out Vayne by 0.3 CS per minute — a moderate farming advantage that adds up to roughly 5 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Brand.
Damage
886Vayne
1,089Brand
Brand heavily out-damages Vayne by 203 DMG/min, dominating both short trades and all-in fights. Vayne should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Brand's sustained damage advantage take over.
Economy
13,061Vayne
13,047Brand
Vayne and Brand generate nearly equal gold per game, with just a 14 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
0.3Vayne
1.4Brand
Brand brings significantly more crowd control than Vayne, with 1.0 more seconds of CC per minute. This large utility gap makes Brand far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Vayne should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
730Vayne
469Brand
Vayne vastly out-sustains Brand, healing and mitigating 261 more damage per minute. This massive durability gap means Vayne can absorb significant punishment and remain in lane while Brand is forced to recall. Building grievous wounds early is essential for Brand, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Brand

Gunmetal Greaves is the optimal boots choice against Brand, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Brand are Blade of The Ruined King, Guinsoo's Rageblade and Experimental Hexplate. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Brand matchup.

Early Game vs Late Game

Early Game
Brand
52.2%
+4.3% advantage
Vayne early game win rateVayne47.8%
Brand early game win rateBrand52.2%
Late Game
Brand
59.3%
+18.5% advantage
Vayne late game win rateVayne40.7%
Brand late game win rateBrand59.3%

During the early laning phase (first 15 minutes), Brand has a meaningful 52.2% win rate, outperforming Vayne by 4.3 percentage points. Brand players should look to press this advantage through aggressive trades, wave priority, and early jungle coordination.

Brand is far superior in the late game (25+ minutes), boasting a 59.3% win rate — 18.5 points above Vayne. Extended games heavily favor Brand, whose kit and scaling make them a dominant force in team fights and objective control.

Brand holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Vayne Runes Against Brand

Precision rune tree - Vayne primary runes vs BrandPrecision
Lethal Tempo - best Vayne rune vs BrandTriumph - best Vayne rune vs BrandLegend: Alacrity - best Vayne rune vs BrandCut Down - best Vayne rune vs Brand
Inspiration rune tree - Vayne secondary runes vs BrandInspiration
Magical Footwear - best Vayne rune vs BrandTriple Tonic - best Vayne rune vs Brand
100.0% WR

The Precision and Inspiration rune setup gives Vayne the best tools to compete against Brand in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Vayne matchup data for League of Legends patch 26.7. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.02%3576.081713,23145.3%52.0%
52.47%3246.289813,59649.3%55.2%
48.09%3146.283212,81944.0%52.7%
49.01%3025.982512,93747.5%50.3%
52.94%2726.083913,07152.8%53.1%
45.37%2276.496014,25446.9%44.2%
50.00%2226.493713,71750.0%50.0%
52.71%2036.585613,74148.9%56.0%
52.32%1516.582813,28755.4%49.4%
58.39%1496.695312,70051.6%63.5%
51.30%1155.881313,71761.5%42.9%
47.71%1096.088213,23938.2%57.4%
55.67%976.488012,62559.6%51.1%
51.55%976.380612,73552.5%50.0%
50.00%945.983213,59546.7%53.1%
36.36%886.279012,98330.0%41.7%
47.44%786.692813,28446.3%48.6%
61.33%756.692412,10266.7%55.6%
55.56%726.185813,24745.2%63.4%
57.35%686.085313,57456.0%58.1%
36.76%686.288112,39436.7%36.8%
52.54%596.383712,51848.5%57.7%
42.37%596.287012,82834.4%51.9%
38.60%575.760511,22540.0%37.0%
37.50%565.560110,77030.4%42.4%
43.40%536.21,04512,46744.4%42.3%
44.00%506.188613,06147.8%40.7%
53.06%496.11,21413,80450.0%55.2%
65.91%446.186913,29266.7%65.4%
56.82%445.692114,04761.1%53.9%
43.18%445.799611,54831.3%50.0%
50.00%406.384813,58435.3%60.9%
55.00%405.989314,58823.1%70.4%
57.50%406.395114,24860.0%56.7%
48.72%396.595213,49157.9%40.0%
57.89%386.01,02912,41355.0%61.1%
42.11%386.192313,74144.4%40.0%
54.05%377.092811,69252.4%56.3%
40.54%375.880412,22541.2%40.0%
40.00%355.71,14111,80838.9%41.2%
55.88%346.585611,12557.9%53.3%
50.00%326.098613,59966.7%43.5%
66.67%306.289612,54050.0%81.3%
56.67%306.298113,89653.9%58.8%
48.28%296.785812,18028.6%66.7%
55.17%296.31,02413,69462.5%46.1%
51.85%275.798412,39145.5%56.3%
61.54%266.185111,71961.5%61.5%
64.00%256.080811,77055.6%68.8%
44.00%256.892712,26342.9%45.5%
33.33%246.483511,60541.7%25.0%
56.52%235.592112,42462.5%53.3%
43.48%236.383712,92160.0%30.8%
40.91%226.678811,10141.7%40.0%
52.38%215.992313,47740.0%63.6%
60.00%205.290914,35220.0%73.3%
47.37%196.91,00811,89263.6%25.0%
50.00%186.273213,04560.0%37.5%
50.00%186.21,05312,78455.6%44.4%
44.44%186.483711,79542.9%45.5%
50.00%185.875412,37328.6%63.6%
76.47%176.91,02114,29680.0%75.0%
29.41%176.982911,89737.5%22.2%
41.18%176.086215,19160.0%33.3%
43.75%166.083811,77362.5%25.0%
56.25%166.690711,52757.1%55.6%
37.50%165.465913,20816.7%50.0%
68.75%166.793713,92583.3%60.0%
53.33%155.968611,41937.5%71.4%
73.33%156.485112,62177.8%66.7%
50.00%145.785111,11416.7%75.0%
42.86%144.364512,05114.3%71.4%
53.85%133.388514,16275.0%44.4%
53.85%135.71,05513,76250.0%55.6%
58.33%125.656210,02757.1%60.0%
25.00%124.586213,08325.0%25.0%
50.00%126.378413,32833.3%66.7%
27.27%116.277113,46233.3%25.0%
63.64%116.387415,82666.7%62.5%
36.36%116.665110,70650.0%20.0%
45.45%115.591912,62950.0%40.0%
72.73%116.474510,85071.4%75.0%
45.45%116.01,06414,50840.0%50.0%
70.00%106.699613,49075.0%66.7%
40.00%106.887613,21633.3%50.0%
55.56%96.393712,28633.3%100.0%
44.44%96.21,07715,702100.0%28.6%
33.33%96.877411,06920.0%50.0%
25.00%85.569310,37825.0%25.0%
50.00%85.99738,78533.3%100.0%
37.50%81.983414,72733.3%40.0%
42.86%75.690112,809100.0%20.0%
0.00%76.655810,7000.0%0.0%
42.86%74.665114,53850.0%40.0%
71.43%76.168213,12675.0%66.7%
57.14%75.588812,31625.0%100.0%
57.14%75.489512,10050.0%66.7%
42.86%74.077311,64333.3%50.0%
57.14%72.51,31315,57625.0%100.0%
33.33%64.65709,10525.0%50.0%
66.67%65.91,08915,49350.0%75.0%
50.00%65.776213,18250.0%50.0%
50.00%61.989114,832100.0%40.0%
16.67%65.384410,4420.0%33.3%
0.00%65.979510,7240.0%0.0%
83.33%66.196311,361100.0%50.0%
50.00%66.380413,574100.0%40.0%
40.00%54.793914,778100.0%0.0%
60.00%51.71,19517,6480.0%75.0%
20.00%51.56919,37833.3%0.0%
60.00%55.31,10015,380100.0%50.0%
20.00%56.891512,5530.0%33.3%
40.00%56.51,02117,6030.0%40.0%

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Vayne vs Brand - Frequently Asked Questions

How does Vayne do against Brand in League of Legends?

Brand wins the Vayne vs Brand matchup with a 56.0% win rate compared to Vayne's 44.0%, a 12.0 percentage point difference. This data is based on 50 recent ranked games in patch 26.7.

How does Vayne do against Brand in the early game?

In the early game, Brand has the advantage against Vayne with a 52.2% win rate versus 47.8%. Brand players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Brand in the late game?

In the late game, Brand takes over the Vayne vs Brand matchup with a 59.3% win rate compared to 40.7%. Brand scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Brand matchup?

Brand wins the matchup against Vayne with a 56.0% win rate in League of Legends patch 26.7. The 12.0 percentage point advantage means Brand is significantly favored in this lane matchup based on 50 games analyzed.

What is the best Vayne build against Brand?

The best Vayne build against Brand includes Blade of The Ruined King, Guinsoo's Rageblade, Experimental Hexplate with Gunmetal Greaves. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Brand?

The best Vayne runes against Brand use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Brand matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Brand?

No, Vayne struggles against Brand with only a 44.0% win rate. Brand has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Brand's lead.

How do I play Vayne against Brand?

When playing Vayne against Brand, play cautiously and avoid Brand's power spikes. Look for jungle assistance and team-dependent plays since Brand has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.